Process for preparing bioactive protein-enriched whey products
    6.
    发明申请
    Process for preparing bioactive protein-enriched whey products 审中-公开
    制备富含生物活性蛋白的乳清产品的方法

    公开(公告)号:US20050208638A1

    公开(公告)日:2005-09-22

    申请号:US10806053

    申请日:2004-03-22

    摘要: The present invention involves the discovery that various liquid (whey) streams drained or expelled from cheese curd after salt addition in the preparation of cheese contain enriched levels of bioactive proteins such as lactoferrin, lactoperoxidase, immunoglobulins, and growth factors. According to the invention, these proteins may be further enriched through manipulation of the cheese salting process as described herein. The methods of the invention may be used to produce various whey products with enriched levels of all the above bioactive proteins present and, through manipulation of salting conditions, to enrich these proteins selectively.

    摘要翻译: 本发明涉及发现,在酪乳制品中加入盐后,从干酪凝乳中排出或排出的各种液体(乳清)流含有富含水平的生物活性蛋白如乳铁蛋白,乳过氧化物酶,免疫球蛋白和生长因子。 根据本发明,这些蛋白质可以通过如本文所述的奶酪盐化过程的操作进一步富集。 本发明的方法可用于生产具有所有上述生物活性蛋白质富集水平的各种乳清产品,并且通过操作盐析条件来选择性富集这些蛋白质。

    Whey treatment process for achieving high concentration of &agr;-lactalbumin
    7.
    发明授权
    Whey treatment process for achieving high concentration of &agr;-lactalbumin 有权
    用于实现高浓度α-乳清蛋白的乳清处理过程

    公开(公告)号:US06312755B1

    公开(公告)日:2001-11-06

    申请号:US09356124

    申请日:1999-07-16

    申请人: Chao Wu

    发明人: Chao Wu

    IPC分类号: A23J100

    摘要: A method of making an &agr;-lactalbumin enriched whey protein product is described. The method involves the treatment of a whey protein product with an acid to lower the pH of the whey protein product to 4.0 or below. This pH-lowering step allows the &agr;-lactalbumin molecules to be concentrated more efficiently.

    摘要翻译: 描述了制备富含α-乳白蛋白的乳清蛋白产物的方法。 该方法涉及用酸处理乳清蛋白产物以将乳清蛋白产物的pH降至4.0或更低。 该pH降低步骤可以更有效地浓缩α-乳白蛋白分子。

    Aryl (ethanoic) propanoic acid ascorbyl ester, preparation method thereof and medicament containing the same
    8.
    发明授权
    Aryl (ethanoic) propanoic acid ascorbyl ester, preparation method thereof and medicament containing the same 有权
    (乙酸)丙酸抗坏血酸酯,其制备方法和含有它的药物

    公开(公告)号:US08703975B2

    公开(公告)日:2014-04-22

    申请号:US13320101

    申请日:2009-12-24

    IPC分类号: C07D307/62

    摘要: The present invention designs and synthesizes the ascorbyl ester derivatives of the aryl (ethanoic) propanoic acid non-steroidal anti-inflammatory medicaments, such as ibuprofen, ketoprofen and naproxen, and addition salt of the derivatives with pharmaceutical acid or pharmaceutical alkaline. The non-steroidal anti-inflammatory medicament which takes the ibuprofen as the representative is a common antipyretic analgesic medicament. The invention has remarkable antipyretic and analgesic effects and good safety except for anti-inflammatory effect, thus being not only suitable for adults, but also suitable for the elderly people, infants and children. The aryl (ethanoic) propanoic acid ascorbyl ester can be converted into ascorbyl ester derivatives and the addition salts of the derivatives with pharmaceutical acid or pharmaceutical alkaline, which can improve the water solubility thereof, facilitate intravenously administration, reduce the onset time, improve the bioavailability, reduce the stimulation effect to gastrointestinal tract, and enhance the penetrating capacity to hemato encephalic barrier, and can be used as a novel medicament to be applied for antiphlogistic, antipyresis, analgesia, treatment of arthritis, dysmenorrheal, multiple sclerosis, pneumonia cystic fibrosis and patent ductus arteriosus of premature infants, and prevention and treatment of cerebral apoplexy, hypoxic-ischemic brain damage, senile dementia and certain cancers.

    摘要翻译: 本发明设计和合成芳基(乙酸)丙酸非甾体抗炎药物如布洛芬,酮洛芬和萘普生的抗坏血酸酯衍生物,以及衍生物与药物酸或药物碱的加成盐。 以布洛芬为代表的非甾体抗炎药是常见的解热止痛药。 本发明除抗炎作用外,具有明显的解热镇痛作用,安全性好,不仅适用于成人,而且适用于老年人,婴儿和儿童。 芳基(乙酸)丙酸抗坏血酸酯可以转化为抗坏血酸酯衍生物,并且衍生物的加成盐与药物酸或药物碱性可以改善其水溶性,有助于静脉内施用,减少发病时间,提高生物利用度 降低对胃肠道的刺激作用,增强血液渗透屏障的穿透能力,可用作新型药物,用于消炎止痛,止痛,止痛,治疗关节炎,痛经,多发性硬化,肺炎囊性纤维化,以及 早产儿动脉导管未闭,预防和治疗脑中风,缺氧缺血性脑损伤,老年性痴呆和某些癌症。

    Process for preparing bioactive protein-enriched whey products
    9.
    发明授权
    Process for preparing bioactive protein-enriched whey products 有权
    制备富含生物活性蛋白的乳清产品的方法

    公开(公告)号:US08389039B2

    公开(公告)日:2013-03-05

    申请号:US12366343

    申请日:2009-02-05

    IPC分类号: A23C21/00

    摘要: The present invention involves the discovery that various liquid (whey) streams drained or expelled from cheese curd after salt addition in the preparation of cheese contain enriched levels of bioactive proteins such as lactoferrin, lactoperoxidase, immunoglobulins, and growth factors. According to the invention, these proteins may be further enriched through manipulation of the cheese salting process as described herein. The methods of the invention may be used to produce various whey products with enriched levels of all the above bioactive proteins present and, through manipulation of salting conditions, to enrich these proteins selectively.

    摘要翻译: 本发明涉及发现,在酪乳制品中加入盐后,从干酪凝乳中排出或排出的各种液体(乳清)流含有富含水平的生物活性蛋白如乳铁蛋白,乳过氧化物酶,免疫球蛋白和生长因子。 根据本发明,这些蛋白质可以通过如本文所述的奶酪盐化过程的操作进一步富集。 本发明的方法可用于生产具有所有上述生物活性蛋白质富集水平的各种乳清产品,并且通过操作盐析条件来选择性富集这些蛋白质。

    Method of dynamically controlling program verify levels in multilevel memory cells
    10.
    发明申请
    Method of dynamically controlling program verify levels in multilevel memory cells 有权
    在多级存储单元中动态控制程序验证级别的方法

    公开(公告)号:US20060164884A1

    公开(公告)日:2006-07-27

    申请号:US11043854

    申请日:2005-01-25

    申请人: Chao Wu

    发明人: Chao Wu

    IPC分类号: G11C16/04

    摘要: Pre-program verify levels for a multilevel read-only memory cell are generated dynamically. A determination takes into account a program verify level, an over-program budget, and a second-bit effect budget to generate pre-program verify levels. The generated pre-program verify levels mitigate issues of over-programming, hard-to-program, and second-bit effect.

    摘要翻译: 动态生成多级只读存储单元的预编程验证级别。 确定考虑到程序验证级别,过程计划预算和第二位效应预算,以生成预编程验证级别。 生成的预编程验证级别可以减轻过度编程,难以编程和第二位影响的问题。