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13 条记录 (耗时 0.051 秒)

    Voice coil motor for a disc drive
    1.
    发明授权
    Voice coil motor for a disc drive 失效
    用于磁盘驱动器的音圈电机

    公开(公告)号：US5654848A

    公开(公告)日：1997-08-05

    申请号：US954981

    申请日：1992-09-30

    申请人： Michael Alan Maiers ,  Michael John Raffetto ,  Chul Soo Kim ,  Fredrick Frank Kazmierczak ,  Bradley Kelemen

    发明人： Michael Alan Maiers ,  Michael John Raffetto ,  Chul Soo Kim ,  Fredrick Frank Kazmierczak ,  Bradley Kelemen

    IPC分类号： G11B21/08 ,  G11B5/012

    CPC分类号： G11B21/083

    摘要： A reduced-height structure for a voice coil motor which forms a portion of the actuator in a disc drive data storage device includes a through opening in the base member of the disc drive housing within which the lower pole piece of the voice coil motor is mounted. A top pole piece of the Voice coil motor is mounted directly to the top cover of the disc drive housing and proper spacing between the top pole piece and the voice coil motor components mounted to the base a member is determined and maintained by a precisely machined surface in the base member. The lower pole piece is preferably mounted to the base member with cold-flowed brass rivets.

    摘要翻译： 用于在盘驱动数据存储装置中形成致动器的一部分的音圈电动机的降低高度结构包括在盘驱动器壳体的基底构件中的通孔，其中安装有音圈电机的下极片 。 音圈电机的顶极件直接安装在磁盘驱动器外壳的顶盖上，顶极件与安装在基座上的音圈电机部件之间的适当间距由精确加工的表面确定并保持 在基地的成员。 下极靴优选地用冷流黄铜铆钉安装到基座部件上。

    Proteorhodopsin mutants with improved optical characteristics
    2.
    发明申请
    Proteorhodopsin mutants with improved optical characteristics 失效
    具有改善的光学特性的蛋白质视紫红质突变体

    公开(公告)号：US20050095605A1

    公开(公告)日：2005-05-05

    申请号：US10724264

    申请日：2003-11-26

    申请人： Rasmus Jensen ,  Bradley Kelemen

    发明人： Rasmus Jensen ,  Bradley Kelemen

    IPC分类号： C07H21/04 ,  C07K14/705 ,  C12Q1/68 ,  F21L4/04 ,  G11B7/246

    CPC分类号： C07H21/04 ,  B42D2035/24 ,  C07K14/195 ,  C07K14/705 ,  G11B7/245 ,  G11B7/246 ,  G11B7/2531 ,  G11B7/2532 ,  G11B7/2533 ,  G11B7/2539

    摘要： The present invention is directed to a proteorhodopsin mutant having improved optical characteristics. One improved optical characteristic is having a lower pH (pKrh) at which equal concentrations of the acidic and basic spectral form of the proteorhodopsin molecules are present. Another improved optical characteristic is having a smaller difference in maximum absorption wavelength between the basic and the acidic form. The mutant comprises a mutation in a conserved amino acid residue of a proteorhodopsin variant, which causes spectral shifts. A preferred mutation site is a conserved histidine residue at amino acid position 75 of Bac31A8, or position 77 of Hot75m1, or its equivalent position of a proteorhodopsin variant. Another preferred mutation site is a conserved arginine residue at amino acid position 94 of Bac31A8, or position 96 of Hot75m1, or its equivalent position of a proteorhodopsin variant.

    摘要翻译： 本发明涉及具有改善的光学特性的蛋白质视紫红质突变体。 一个改进的光学特性是具有较低的pH（pK），其中存在等同浓度的蛋白质视紫红质分子的酸性和碱性光谱形式。 另一改进的光学特性在碱性和酸性形式之间的最大吸收波长的差异较小。 突变体包含蛋白质视紫红质变体的保守氨基酸残基中的突变，其导致光谱偏移。 优选的突变位点是Bac31A8的氨基酸位置75处的保守的组氨酸残基，或Hot75m1的77位或其蛋白质视紫红质变体的等同位置。 另一个优选的突变位点是Bac31A8的氨基酸位置94的保守精氨酸残基，或Hot75m1的位置96或其蛋白质视紫红质变体的等同位置。

    Sensor inserter methods of use
    3.
    发明申请
    Sensor inserter methods of use 有权
    传感器插入器使用方法

    公开(公告)号：US20080064941A1

    公开(公告)日：2008-03-13

    申请号：US11899870

    申请日：2007-09-06

    申请人： Jeffery Funderburk ,  Duane Yamasaki ,  Brian VanHiel ,  Stephen Flynn ,  Bradley Kelemen

    发明人： Jeffery Funderburk ,  Duane Yamasaki ,  Brian VanHiel ,  Stephen Flynn ,  Bradley Kelemen

    IPC分类号： A61B5/145

    CPC分类号： A61B5/1473 ,  A61B5/1451 ,  A61B5/14532 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/6833 ,  A61B5/6849 ,  A61B17/3468 ,  A61M2205/3507 ,  A61M2230/201 ,  A61N1/05 ,  A61N1/08

    摘要： An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte, such as blood glucose. An inserter having a retractable introducer is provided for subcutaneously implanting the sensor in a predictable and reliable fashion.

    摘要翻译： 分析物监测器包括传感器，传感器控制单元和显示单元。 传感器控制单元通常具有适于放置在皮肤上并适于接收电化学传感器的一部分的壳体。 传感器控制单元还包括设置在壳体上并被配置为耦合到传感器上的两个或更多个接触垫的两个或更多个导电触头。 发射器设置在壳体中并且耦合到多个导电接触件，用于传送使用传感器获得的数据。 显示单元具有用于接收由传感器控制单元的发送器发送的数据的接收器和耦合到接收器的显示器，用于显示诸如血糖的分析物的水平的指示。 提供具有可伸缩导引器的插入器，用于以可预测和可靠的方式皮下植入传感器。

    Proteorhodopsin mutants with improved optical characteristics
    6.
    发明授权
    Proteorhodopsin mutants with improved optical characteristics 失效
    具有改善的光学特性的蛋白质视紫红质突变体

    公开(公告)号：US07501488B2

    公开(公告)日：2009-03-10

    申请号：US10724264

    申请日：2003-11-26

    申请人： Rasmus B. Jensen ,  Bradley Kelemen

    发明人： Rasmus B. Jensen ,  Bradley Kelemen

    IPC分类号： C07K1/00 ,  C12P21/06

    CPC分类号： C07H21/04 ,  B42D2035/24 ,  C07K14/195 ,  C07K14/705 ,  G11B7/245 ,  G11B7/246 ,  G11B7/2531 ,  G11B7/2532 ,  G11B7/2533 ,  G11B7/2539

    摘要： The present invention is directed to a proteorhodopsin mutant having improved optical characteristics. One improved optical characteristic is having a lower pH (pKrh) at which equal concentrations of the acidic and basic spectral form of the proteorhodopsin molecules are present. Another improved optical characteristic is having a smaller difference in maximum absorption wavelength between the basic and the acidic form. The mutant comprises a mutation in a conserved amino acid residue of a proteorhodopsin variant, which causes spectral shifts. A preferred mutation site is a conserved histidine residue at amino acid position 75 of Bac31A8, or position 77 of Hot75m1, or its equivalent position of a proteorhodopsin variant. Another preferred mutation site is a conserved arginine residue at amino acid position 94 of Bac31A8, or position 96 of Hot75m1, or its equivalent position of a proteorhodopsin variant.

    摘要翻译： 本发明涉及具有改善的光学特性的蛋白质视紫红质突变体。 一个改进的光学特征是具有较低的pH（pKrh），在该pH下，蛋白质视紫红质分子的酸性和碱性光谱形式的等浓度存在。 另一改进的光学特性在碱性和酸性形式之间的最大吸收波长的差异较小。 突变体包含蛋白质视紫红质变体的保守氨基酸残基中的突变，其导致光谱偏移。 优选的突变位点是Bac31A8的氨基酸位置75处的保守的组氨酸残基，或Hot75m1的77位或其蛋白质视紫红质变体的等同位置。 另一个优选的突变位点是Bac31A8的氨基酸位置94的保守精氨酸残基，或Hot75m1的位置96或其蛋白质视紫红质变体的等同位置。