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1.发明授权Organic solid state switches incorporating porphyrin compounds and method for producing organic solid state optical switches 失效掺有卟啉化合物的有机固态开关和制造有机固态光开关的方法
公开(公告)号：US5539100A
公开(公告)日：1996-07-23
申请号：US84093
申请日：1993-07-01
申请人： Michael R. Wasielewski , George L. Gaines , Mark P. Niemczyk , Douglas G. Johnson , David J. Gosztola , Michael P. O'Neil
发明人： Michael R. Wasielewski , George L. Gaines , Mark P. Niemczyk , Douglas G. Johnson , David J. Gosztola , Michael P. O'Neil
IPC分类号： C07D487/22 , C07D519/00 , G02F1/01 , H01L51/30 , H01L31/04
CPC分类号： H01L51/0053 , B82Y10/00 , C07D519/00 , G02F1/0126 , H01L51/0077 , H01L51/0595 , H01L51/42 , Y02E10/549
摘要： A light-intensity dependent molecular switch comprised of a compound which shuttles an electron or a plurality of electrons from a plurality of electron donors to an electron acceptor upon being stimulated with light of predetermined wavelengths, said donors selected from porphyrins and other compounds, and a method for making said compound.
摘要翻译： 一种光强依赖性分子开关，其由在预定波长的光刺激下将电子或多个电子从多个电子给体穿过电子受体的化合物组成，所述供体选自卟啉和其它化合物，以及 制备所述化合物的方法。
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公开(公告)号：US20190046286A1
公开(公告)日：2019-02-14
申请号：US16054292
申请日：2018-08-03
申请人： Michael P. O'Neil , Robert E. Grove
发明人： Michael P. O'Neil , Robert E. Grove
摘要： A system and method for the reduction or inhibition of laser-induced plumes in dermatological and surgical treatments includes a substantially optically clear physical barrier, that does not degrade due to laser exposure, applied to a treatment area. The dermatological treatment is carried out directly through the barrier. In one embodiment, a barrier may be formed by applying to a treatment area a spray or liquid that polymerizes or cures in situ. In another embodiment, the barrier is pre-formed and placed over the treatment area. The barrier acts to reduce or inhibit the dissipation of the plume that would otherwise result from the laser treatment.
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公开(公告)号：US20130053757A1
公开(公告)日：2013-02-28
申请号：US13436087
申请日：2012-03-30
申请人： Michael P. O'Neil
发明人： Michael P. O'Neil
CPC分类号： A61K8/70 , A61B18/203 , A61B2017/00769 , A61B2018/00458 , A61B2018/0047 , A61B2018/00577 , A61K8/0208 , A61K31/025 , A61K41/00 , A61K2800/81 , A61M35/006 , A61N5/0616 , A61N5/062 , A61Q1/145 , A61Q19/00
摘要： A treatment system and method includes use of a chemical facilitator to provide a result-effective event against one or more negative therapeutic effects related to exposing to a light output a skin portion including a condition treatable in whole or in part with light. In one exemplary embodiment for skin treatment including tattoo removal, perfluorodecalin is used to inhibit or resolve whitening, for example to speed a laser therapy session.
摘要翻译： 治疗系统和方法包括使用化学促进器来提供结果有效的事件，以抵抗与光输出相关的一个或多个负面治疗效果，该皮肤部分包括全部或部分可用光治疗的疾病。 在用于包括纹身去除的皮肤处理的一个示例性实施方案中，全氟萘烷用于抑制或分解美白，例如加速激光治疗会话。
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公开(公告)号：US20100069898A1
公开(公告)日：2010-03-18
申请号：US12554831
申请日：2009-09-04
申请人： Michael P. O'Neil , Mark V. Weckwerth , Patrick V. Reichert , Harvey I. Liu , Charles A. Schuetz , Tobin C. Island , Robert E. Grove
发明人： Michael P. O'Neil , Mark V. Weckwerth , Patrick V. Reichert , Harvey I. Liu , Charles A. Schuetz , Tobin C. Island , Robert E. Grove
CPC分类号： A61B18/203 , A61B2017/00057 , A61B2017/00061 , A61B2017/00066 , A61B2017/00172 , A61B2017/00734 , A61B2018/00005 , A61B2018/00452 , A61B2018/00476 , A61B2018/00708 , A61B2018/00827 , A61B2018/2261 , A61B2090/065 , A61N5/0616 , A61N2005/007 , A61N2005/0644 , A61N2005/0652 , A61N2005/0662
摘要： An acne treatment system, device and method includes optical visualization means for identifying areas of skin colonized by the P. acnes bacteria, and further comprises methods, techniques and apparatus for the reduction or elimination of such colonies through the use of light of a power density and wavelength configured to be absorbed by porphyrins produced by the bacteria, resulting in a quenching. Various alternative embodiments are disclosed, including eye safe embodiments, embodiments in which a treatment regimen is provided on a disposable cartridge, embodiments in which the authenticity of the cartridge is verified to ensure proper operation, as well as others.
摘要翻译： 痤疮治疗系统，装置和方法包括用于识别由痤疮丙酸杆菌细菌定植的皮肤区域的光学可视化装置，并且还包括通过使用功率密度的光来减少或消除这种菌落的方法，技术和装置 配置为由细菌产生的卟啉吸收的波长，导致猝灭。 公开了各种替代实施例，包括眼睛安全实施例，其中在一次性药筒上提供治疗方案的实施例，其中验证药筒的真实性以确保正确操作的实施例以及其它实施例。
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公开(公告)号：US20080078401A1
公开(公告)日：2008-04-03
申请号：US11529827
申请日：2006-09-29
申请人： Michael P. O'Neil , Joel C. Colburn , Gary L. Crumback , Charles E. Porges , Alfred Chung , David Hyde
发明人： Michael P. O'Neil , Joel C. Colburn , Gary L. Crumback , Charles E. Porges , Alfred Chung , David Hyde
CPC分类号： A61M16/04 , A61M16/0427 , A61M16/0431 , A61M16/0443 , A61M16/0452 , A61M16/0459 , A61M16/0463 , A61M16/0484 , A61M2205/0266
摘要： There is disclosed an endotracheal tube which has a minimal cross-sectional profile for easy viewing of anatomical features during intubation. After the tube is placed into the trachea, the tube is adapted to increase the diameter. In this manner the tube diameter may be expanded to allow for decreased Work of Breathing (WOB) for patient, while not having so large a diameter as to cause tracheal discomfort.
摘要翻译： 公开了一种气管内管，其具有最小的横截面轮廓，以便于在插管期间容易地观察解剖特征。 在将管置于气管中之后，管适于增加直径。 以这种方式，管直径可以被扩张以允许减少患者的呼吸作用（WOB），而没有如此大的直径导致气管不适。
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公开(公告)号：US20160317421A1
公开(公告)日：2016-11-03
申请号：US15201469
申请日：2016-07-03
申请人： Michael P. O'Neil
发明人： Michael P. O'Neil
CPC分类号： A61K8/70 , A61B18/203 , A61B2017/00769 , A61B2018/00458 , A61B2018/0047 , A61B2018/00577 , A61K8/0208 , A61K31/025 , A61K41/00 , A61K2800/81 , A61M35/006 , A61N5/0616 , A61N5/062 , A61Q1/145 , A61Q19/00
摘要： A treatment system and method includes use of a chemical facilitator to provide a result-effective event against one or more negative therapeutic effects related to exposing to a light output a skin portion including a condition treatable in whole or in part with light. In one exemplary embodiment for skin treatment including tattoo removal, perfluorodecalin is used to inhibit or resolve whitening, for example to speed a laser therapy session.
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公开(公告)号：US09402817B2
公开(公告)日：2016-08-02
申请号：US14832398
申请日：2015-08-21
申请人： Michael P. O'Neil
发明人： Michael P. O'Neil
IPC分类号： A61K33/24 , A61K47/02 , A61K47/14 , A61K47/26 , A61K47/38 , A61K31/025 , A61F13/40 , A61N5/06 , A61Q19/00 , A61B18/20 , A61Q1/14 , A61K8/70 , A61K41/00 , A61B18/00 , A61B17/00
CPC分类号： A61K8/70 , A61B18/203 , A61B2017/00769 , A61B2018/00458 , A61B2018/0047 , A61B2018/00577 , A61K8/0208 , A61K31/025 , A61K41/00 , A61K2800/81 , A61M35/006 , A61N5/0616 , A61N5/062 , A61Q1/145 , A61Q19/00
摘要： A treatment system and method includes use of a chemical facilitator to provide a result-effective event against one or more negative therapeutic effects related to exposing to a light output a skin portion including a condition treatable in whole or in part with light. In one exemplary embodiment for skin treatment including tattoo removal, perfluorodecalin is used to inhibit or resolve whitening, for example to speed a laser therapy session.
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公开(公告)号：US07992561B2
公开(公告)日：2011-08-09
申请号：US11526860
申请日：2006-09-25
CPC分类号： A61B5/091 , A61B5/0836 , A61B5/087 , A61B5/412 , A61M16/0057 , A61M16/04 , A61M16/0415 , A61M16/042 , A61M16/0434 , A61M16/0443 , A61M16/0459 , A61M16/0475 , A61M16/0486 , A61M16/08 , A61M2016/0413 , A61M2016/103 , A61M2230/40 , A61M2230/432
摘要： An airway device is provided that may track the flow of respiratory gases through the device with sensing elements at a plurality of locations along the gas flow path of the device. Such a device may be useful for assessing a variety of clinical states, for adjusting patient ventilator settings, or for determining whether or not an airway device has been properly inserted into a patient airway.
摘要翻译： 提供了一种气道装置，其可以沿着装置的气体流动路径沿着多个位置跟踪具有感测元件的通过装置的呼吸气体的流动。 这样的装置可用于评估各种临床状态，用于调节患者呼吸机设置，或用于确定气道装置是否已被正确地插入到患者气道中。
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公开(公告)号：US20100196343A1
公开(公告)日：2010-08-05
申请号：US12554872
申请日：2009-09-04
申请人： Michael P. O'Neil , Joel Rubin , Drake Stimson
发明人： Michael P. O'Neil , Joel Rubin , Drake Stimson
CPC分类号： A61K8/365 , A61B18/203 , A61B2017/00039 , A61B2017/00057 , A61B2017/00061 , A61B2017/00066 , A61B2017/00172 , A61B2017/00734 , A61B2018/00005 , A61B2018/00452 , A61B2018/00476 , A61B2018/2261 , A61B2090/065 , A61K8/046 , A61K8/31 , A61K8/66 , A61K8/673 , A61K8/922 , A61K2800/28 , A61K2800/81 , A61K2800/88 , A61N5/0616 , A61N5/062 , A61N2005/007 , A61N2005/0644 , A61N2005/0652 , A61N2005/0662 , A61N2005/0663 , A61Q19/00 , A61Q19/10
摘要： Accordingly, a need has arisen for improved compositions, methods, devices, and systems for skin care including, without limitation, topical compositions and phototherapy devices and methods. A skin care method may comprise, in some embodiments, contacting at least a portion of the skin of a subject with a homogeneous, stable, self-foaming composition, illuminating the at least a portion of the skin exclusively with light of a desired wavelength (e.g., from about 390 nm to about 430 nm, and contacting the at least a portion of the skin with an anti-oxidant serum composition.
摘要翻译： 因此，需要改进用于皮肤护理的组合物，方法，装置和系统，包括但不限于局部组合物和光疗装置和方法。 在一些实施方案中，皮肤护理方法可以包括使受试者的至少一部分皮肤与均匀的，稳定的自发泡组合物接触，仅使用所需波长的光照射皮肤的至少一部分（ 例如约390nm至约430nm，并使皮肤的至少一部分与抗氧化血清组合物接触。
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公开(公告)号：US20090216096A1
公开(公告)日：2009-08-27
申请号：US12345377
申请日：2008-12-29
申请人： Matthew B. Bloom , Dana L. Deardorff , Gilbert Hausmann , Paul D. Mannheimer , Michael P. O'Neil , Shannon E. Campbell , Rafael Ostrowski
发明人： Matthew B. Bloom , Dana L. Deardorff , Gilbert Hausmann , Paul D. Mannheimer , Michael P. O'Neil , Shannon E. Campbell , Rafael Ostrowski
IPC分类号： A61B5/1455
CPC分类号： A61B5/0059
摘要： A method and apparatus is provided for measuring a sterol, such as cholesterol, deposited in the skin. Light of two or more wavelengths is emitted toward or into a skin sample and the light is differentially absorbed by the sterol in the skin sample. The differentially absorbed light is detected and the amount of sterol in the skin sample is determined based on the differential absorption.
摘要翻译： 提供了一种测量沉积在皮肤中的固醇如胆固醇的方法和装置。 将两个或更多个波长的光发射到皮肤样品中或向皮肤样品中发射，并且光被皮肤样品中的固醇区别地吸收。 检测差异吸收的光，并且基于差异吸收确定皮肤样品中的固醇的量。
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