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    FLUID CONTROLLING APPARATUS AND METHOD OF CONTROLLING FLUID BY USING THE SAME
    3.
    发明申请
    FLUID CONTROLLING APPARATUS AND METHOD OF CONTROLLING FLUID BY USING THE SAME 有权
    流体控制装置及其使用方法控制流体

    公开(公告)号：US20130086998A1

    公开(公告)日：2013-04-11

    申请号：US13571202

    申请日：2012-08-09

    申请人： June-young LEE ,  Sang-hyun BAEK ,  Hyo-young JEONG ,  Tae-seok SIM ,  Jeong-gun LEE

    发明人： June-young LEE ,  Sang-hyun BAEK ,  Hyo-young JEONG ,  Tae-seok SIM ,  Jeong-gun LEE

    IPC分类号： G01N1/20

    CPC分类号： B01L3/502753 ,  B01L3/5027 ,  B01L2200/0621 ,  B01L2200/141 ,  B01L2300/0681 ,  B01L2300/0861 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2400/0487 ,  G01N2035/00237 ,  G01N2035/0437 ,  Y10T137/4259

    摘要： A fluid controlling apparatus including at least one sample chamber for holding a fluid containing target materials; a cleaning chamber for holding a cleaning solution; a first multi-port connected to the at least one sample chamber through a first channel and connected to the cleaning chamber through a second channel; a filter portion, connected to the first multi-port through a third channel, for filtering the target materials; and a first pump, connected to the filter portion, for applying a pressure; and a method of controlling a fluid using the fluid controlling apparatus, which comprises passing the fluid containing the target materials from the at least one sample chamber to the filter portion; and cleaning a path of the fluid by passing the cleaning solution through the path.

    摘要翻译： 一种流体控制装置，包括用于保持含有目标材料的流体的至少一个样品室; 用于保持清洁溶液的清洁室; 第一多端口，其通过第一通道连接到所述至少一个样品室，并通过第二通道连接到所述清洁室; 过滤器部分，通过第三通道连接到第一多端口，用于过滤目标材料; 以及连接到过滤器部分的用于施加压力的第一泵; 以及使用所述流体控制装置控制流体的方法，所述方法包括将包含所述目标材料的流体从所述至少一个样品室传送到所述过滤器部分; 以及通过使清洁溶液通过路径来清洁流体的路径。

    DEVICE AND METHOD OF SEPARATING CELLS BY USING MAGNETIC FORCE
    8.
    发明申请
    DEVICE AND METHOD OF SEPARATING CELLS BY USING MAGNETIC FORCE 有权
    使用磁力分离细胞的装置和方法

    公开(公告)号：US20120077267A1

    公开(公告)日：2012-03-29

    申请号：US13051251

    申请日：2011-03-18

    申请人： Hun-joo LEE ,  Jeong-gun LEE ,  Mi-jeong SONG ,  Jong-myeon PARK ,  Tae-seok SIM ,  Min-seok S. KIM

    发明人： Hun-joo LEE ,  Jeong-gun LEE ,  Mi-jeong SONG ,  Jong-myeon PARK ,  Tae-seok SIM ,  Min-seok S. KIM

    IPC分类号： C12N5/00 ,  C12M1/00

    CPC分类号： C12M47/04 ,  B01L3/502753 ,  B01L3/502761 ,  B01L2300/0864 ,  B03C1/02 ,  B03C1/14 ,  B03C1/145 ,  C12M1/266 ,  G01N1/4077 ,  Y10T436/25

    摘要： A cell separation device includes a channel or chamber in which a sample flows or moves, the sample including target cells marked with magnetic particles, and non-target cells, and a magnet which generates a magnetic first force in a first direction with respect to the sample within the channel or chamber. The channel or chamber of the cell separation device is applied with a second force in a second direction opposite to the first direction of the magnetic force. According to the cell separation device and a method of separating cells, the target cells move in the first direction by the magnetic force, and the non-target cells move in the second direction by the second force, by simultaneously applying the magnetic force and the second force in opposing directions, thereby separating the target cells from the non-target cells.

    摘要翻译： 细胞分离装置包括样品流动或移动的通道或室，包括标记有磁性颗粒的靶细胞的样品和非靶细胞，以及相对于第一方向产生第一方向的磁性第一力的磁体 样品在通道或室内。 细胞分离装置的通道或腔室以与磁力的第一方向相反的第二方向施加第二力。 根据细胞分离装置和分离细胞的方法，靶细胞通过磁力在第一方向上移动，非靶细胞通过第二力在第二方向上移动，同时施加磁力和 从而将目标细胞与非靶细胞分离。

    TARGET PARTICLES-SEPARATING DEVICE AND METHOD USING MULTI-ORIFICE FLOW FRACTIONATION CHANNEL
    9.
    发明申请
    TARGET PARTICLES-SEPARATING DEVICE AND METHOD USING MULTI-ORIFICE FLOW FRACTIONATION CHANNEL 有权
    目标颗粒分离装置和使用多元流动分离通道的方法

    公开(公告)号：US20110303586A1

    公开(公告)日：2011-12-15

    申请号：US13156630

    申请日：2011-06-09

    申请人： Tae-seok SIM ,  Jeong-gun LEE ,  Hyo-il JUNG ,  Ki-ho KWON

    发明人： Tae-seok SIM ,  Jeong-gun LEE ,  Hyo-il JUNG ,  Ki-ho KWON

    IPC分类号： B03B7/00 ,  B07B1/00

    CPC分类号： B01L3/502761 ,  B01L3/502753 ,  B01L2200/0652 ,  B01L2300/087 ,  B01L2400/0487

    摘要： A device separating target particles in a fluid sample includes first through third multi-orifice flow fractionation (“MOFF”) channels, each including a multi-orifice segment with an inlet and an outlet at opposite ends, and an alternating series of contraction channels and expansion chambers interconnected in a lengthwise direction; a first separation unit including a first separation channel which is interconnected in fluid communication with a center region of the outlet of the first MOFF channel, and first branch channels which are interconnected in fluid communication with sidewall regions of the outlet of the first MOFF channel, and respectively with inlets of the second and third MOFF channels; and buffer inlets which are connected to the inlets of the second and third MOFF channels and through which a buffer flows into the second and third MOFF channels.

    摘要翻译： 分离流体样品中的目标颗粒的装置包括第一至第三多孔流动分馏（“MOFF”）通道，每个通道包括具有相对端的入口和出口的多孔段，以及交替的一系列收缩通道和 膨胀室沿长度方向互相连接; 第一分离单元，包括与第一MOFF通道的出口的中心区域流体连通的第一分离通道和与第一MOFF通道的出口的侧壁区域流体连通地互连的第一分支通道， 并分别具有第二和第三MOFF通道的入口; 以及连接到第二和第三MOFF通道的入口并且缓冲器通过其流入第二和第三MOFF通道的缓冲器入口。

    DEVICE AND METHOD FOR DIFFERENTIATING TARGET CELL
    10.
    发明申请
    DEVICE AND METHOD FOR DIFFERENTIATING TARGET CELL 审中-公开
    用于鉴别目标细胞的装置和方法

    公开(公告)号：US20130055473A1

    公开(公告)日：2013-02-28

    申请号：US13591571

    申请日：2012-08-22

    申请人： Young-nam KWON ,  Kee-won KIM ,  Min-seok KIM ,  Hyouk-soo HAN ,  Jeong-gun LEE ,  Hee-goo KIM

    发明人： Young-nam KWON ,  Kee-won KIM ,  Min-seok KIM ,  Hyouk-soo HAN ,  Jeong-gun LEE ,  Hee-goo KIM

    IPC分类号： G01Q20/00

    CPC分类号： G01Q30/04 ,  G01Q60/42

    摘要： A device for differentiating a target cell includes a cantilever including a fixed end and a free end, where the cantilever is elastically deformable, a tip disposed on the free end of the cantilever, where the tip contacts a surface of a cell, a measurement unit connected to the fixed end of the cantilever, where the measurement unit measures a degree of a repulsive force based on an elastic deformation of the cantilever, and a conversion unit which converts the repulsive force measured by the measurement unit into a modulus of elasticity derived from the surface of the cell.

    摘要翻译： 用于区分目标单元的装置包括悬臂，其包括固定端和自由端，其中悬臂可弹性变形，设置在悬臂的自由端上的尖端，其中尖端接触单元表面，测量单元 连接到悬臂的固定端，其中测量单元基于悬臂的弹性变形来测量排斥力的程度;以及转换单元，其将由测量单元测量的排斥力转换为由 电池的表面。