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    NOVEL COMPOUNDS
    3.
    发明申请
    NOVEL COMPOUNDS 审中-公开
    新型化合物

    公开(公告)号：US20080004295A1

    公开(公告)日：2008-01-03

    申请号：US11548343

    申请日：2006-10-11

    申请人： Paul Gore ,  Vipulkumar Patel ,  Ann Walker

    发明人： Paul Gore ,  Vipulkumar Patel ,  Ann Walker

    IPC分类号： A61K31/519 ,  A61P11/00 ,  A61P11/02 ,  A61P19/02 ,  A61P37/08 ,  A61P9/10 ,  C07D487/04

    CPC分类号： C07D487/04

    摘要： Pyrrolopyrimidine derivatives of formula (I) are inhibitors of Spleen Tyrosine kinase (Syk) and therefore of potential therapeutic benefit in the treatment of diseases and conditions associated with inappropriate Syk activity, in particular in the treatment of inflammatory and allergic diseases.

    摘要翻译： 式（I）的吡咯并嘧啶衍生物是脾脏酪氨酸激酶（Syk）的抑制剂，因此在治疗与不适当的Syk活性相关的疾病和病症方面具有潜在的治疗益处，特别是治疗炎性和过敏性疾病。

    Offset launch mode from nanotaper waveguide into multimode fiber
    6.
    发明授权
    Offset launch mode from nanotaper waveguide into multimode fiber 有权
    从纳米孔波导到多模光纤的偏移发射模式

    公开(公告)号：US07706644B2

    公开(公告)日：2010-04-27

    申请号：US12218367

    申请日：2008-07-15

    申请人： Mark Webster ,  Prakash Gothoskar ,  Vipulkumar Patel ,  David Piede

    发明人： Mark Webster ,  Prakash Gothoskar ,  Vipulkumar Patel ,  David Piede

    IPC分类号： G02B6/26

    CPC分类号： G02B6/30 ,  G02B6/3598 ,  G02B6/3636 ,  G02B6/3652 ,  G02B6/3692 ,  G02B6/4249

    摘要： One or more nanotaper coupling waveguides formed within an optical substrate allows for straightforward, reproducible offset launch conditions to be achieved between an incoming signal and the core region of a multimode fiber (which may be disposed along an alignment fixture formed in the optical substrate), fiber array or other multimode waveguiding structure. Offset launching of a single mode signal into a multimode fiber couples the signal into favorable spatial modes which reduce the presence of differential mode dispersion along the fiber. This approach to providing single mode signal coupling into legacy multimode fiber is considered to be an improvement over the prior art which required the use of an interface element between a single mode fiber and multimode fiber, limiting the number of propagating signals and applications for the legacy multimode fiber. An optical switch may be used to select the specific nanotaper(s) for coupling into the multimode fiber.

    摘要翻译： 形成在光学衬底内的一个或多个纳米锥耦合波导允许在多模光纤（其可以沿着形成在光学衬底中的对准夹具设置）的入射信号和芯区域之间实现简单，可再现的偏移发射条件， 光纤阵列或其他多模波导结构。 偏移将单模信号发射到多模光纤中将信号耦合到有利的空间模式，这降低了沿着光纤的差分色散的存在。 将单模信号耦合提供给传统多模光纤的这种方法被认为是对需要使用单模光纤和多模光纤之间的接口元件的现有技术的改进，限制了传播信号的数量和遗留的应用 多模光纤 可以使用光学开关来选择用于耦合到多模光纤的特定纳米锥。

    Silicon modulator offset tuning arrangement
    7.
    发明授权
    Silicon modulator offset tuning arrangement 有权
    硅调制器偏移调谐布置

    公开(公告)号：US07447395B2

    公开(公告)日：2008-11-04

    申请号：US11810591

    申请日：2007-06-06

    申请人： Robert Keith Montgomery ,  Margaret Ghiron ,  Prakash Gothoskar ,  Paulius Mindaugas Mosinskis ,  Vipulkumar Patel ,  Kalpendu Shastri ,  Mark Webster

    发明人： Robert Keith Montgomery ,  Margaret Ghiron ,  Prakash Gothoskar ,  Paulius Mindaugas Mosinskis ,  Vipulkumar Patel ,  Kalpendu Shastri ,  Mark Webster

    IPC分类号： G02B6/12 ,  G02F1/295

    CPC分类号： G02F1/025 ,  G02F1/0147 ,  G02F1/225 ,  G02F2201/126

    摘要： A silicon-based optical modulator structure includes one or more separate localized heating elements for changing the refractive index of an associated portion of the structure and thereby providing corrective adjustments to address unwanted variations in device performance. Heating is provided by thermo-optic devices such as, for example, silicon-based resistors, silicide resistors, forward-biased PN junctions, and the like, where any of these structures may easily be incorporated with a silicon-based optical modulator. The application of a DC voltage to any of these structures will generate heat, which then transfers into the waveguiding area. The increase in local temperature of the waveguiding area will, in turn, increase the refractive index of the waveguiding in the area. Control of the applied DC voltage results in controlling the refractive index.

    摘要翻译： 基于硅的光学调制器结构包括一个或多个单独的局部加热元件，用于改变结构的相关部分的折射率，从而提供校正调整以解决器件性能的不期望的变化。 加热由诸如硅基电阻器，硅化物电阻器，正向偏置PN结等的热光器件提供，其中这些结构中的任何一种可以容易地与硅基光学调制器结合。 对这些结构中的任何一个施加直流电压将产生热量，然后传递到波导区域。 波导区域的局部温度的增加又将增加该区域中波导的折射率。 施加的直流电压的控制导致控制折射率。

    Vertical stacking of multiple integrated circuits including SOI-based optical components
    8.
    发明申请
    Vertical stacking of multiple integrated circuits including SOI-based optical components 审中-公开
    包括基于SOI的光学元件的多个集成电路的垂直堆叠

    公开(公告)号：US20060177173A1

    公开(公告)日：2006-08-10

    申请号：US11346718

    申请日：2006-02-03

    申请人： Kalpendu Shastri ,  Vipulkumar Patel ,  David Piede ,  John Fangman

    发明人： Kalpendu Shastri ,  Vipulkumar Patel ,  David Piede ,  John Fangman

    IPC分类号： G02B6/12 ,  G02B6/26 ,  G02B6/42 ,  G02B6/10

    CPC分类号： G02B6/42 ,  G02B6/4214 ,  G02B6/43 ,  G02F1/025 ,  H01L31/12

    摘要： A vertical stack of integrated circuits includes at least one CMOS electronic integrated circuit (IC), an SOI-based opto-electronic integrated circuit structure, and an optical input/output coupling element. A plurality of metalized vias may be formed through the thickness of the stack so that electrical connections can be made between each integrated circuit. Various types of optical input/output coupling can be used, such as prism coupling, gratings, inverse tapers, and the like. By separating the optical and electrical functions onto separate ICs, the functionalities of each may be modified without requiring a re-design of the remaining system. By virtue of using SOI-based opto-electronics with the CMOS electronic ICs, a portion of the SOI structure may be exposed to provide access to the waveguiding SOI layer for optical coupling purposes.

    摘要翻译： 集成电路的垂直堆叠包括至少一个CMOS电子集成电路（IC），基于SOI的光电集成电路结构以及光输入/输出耦合元件。 可以通过堆叠的厚度形成多个金属化通孔，使得可以在每个集成电路之间进行电连接。 可以使用各种类型的光输入/输出耦合，例如棱镜耦合，光栅，逆锥等。 通过将光学和电气功能分离到单独的IC上，可以修改每个功能，而不需要重新设计剩余的系统。 通过使用具有CMOS电子IC的基于SOI的光电子器件，SOI结构的一部分可能被暴露以提供对波导SOI层的访问以用于光学耦合目的。