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102 条记录 (耗时 0.074 秒)

    Remedy for Diabetes
    1.
    发明申请
    Remedy for Diabetes 审中-公开
    补救糖尿病

    公开(公告)号：US20070259927A1

    公开(公告)日：2007-11-08

    申请号：US11660939

    申请日：2005-08-25

    申请人： Nobuhiro Suzuki ,  Yusuke Moritoh ,  Masanori Watanabe

    发明人： Nobuhiro Suzuki ,  Yusuke Moritoh ,  Masanori Watanabe

    IPC分类号： A61K31/4436 ,  A61K31/4439 ,  A61P3/10

    CPC分类号： A61K31/40 ,  A61K31/4439 ,  A61K31/455 ,  A61K31/4985 ,  A61K45/06

    摘要： The present invention provides an agent for increasing the pancreatic insulin content useful for the treatment of diabetes and the like. In one embodiment, the present invention provides an agent for increasing the pancreatic insulin content, which contains a blood glucose lowering drug that does not stimulate insulin secretion, and a dipeptidyl-peptidase IV inhibitor in combination.

    摘要翻译： 本发明提供了用于增加可用于治疗糖尿病等的胰岛素含量的药剂。 在一个实施方案中，本发明提供了用于增加胰岛素含量的试剂，其含有不刺激胰岛素分泌的降血糖药物和组合的二肽基肽酶IV抑制剂。

    Bread packaging system
    2.
    发明授权
    Bread packaging system 有权
    面包包装系统

    公开(公告)号：US08887476B2

    公开(公告)日：2014-11-18

    申请号：US12929165

    申请日：2011-01-05

    申请人： Nobuhiro Suzuki ,  Shuichi Iribe ,  Michinori Watanabe ,  Seiichi Akutsu

    发明人： Nobuhiro Suzuki ,  Shuichi Iribe ,  Michinori Watanabe ,  Seiichi Akutsu

    IPC分类号： B65B5/06

    CPC分类号： B65B25/16

    摘要： A bread packaging system comprising: a movable member on which a scoop for holding a packaging member to package bread is mounted; a guide member for defining a moving path along which the movable member is moved; a reciprocating motion mechanism having an endless revolving member for reciprocating the movable member along the guide member; and a link member for linking the endless revolving member with the movable member, wherein the bread packaging system is configured to reciprocate the movable member along the guide member by revolving the endless revolving member in one direction.

    摘要翻译： 一种面包包装系统，包括：可移动部件，其上安装有用于保持包装部件以包装面包的勺子; 引导构件，用于限定可移动构件沿其移动的移动路径; 往复运动机构，其具有用于使可动构件沿导向件往复运动的环形旋转构件; 以及用于将环形旋转构件与可动构件连接的连杆构件，其中，所述面包包装系统构造成通过使所述环形旋转构件沿一个方向旋转来使所述可动构件沿着所述引导构件往复运动。

    Thienopyrimidine compounds and use thereof
    3.
    发明授权
    Thienopyrimidine compounds and use thereof 有权
    噻吩并嘧啶化合物及其用途

    公开(公告)号：US08735401B2

    公开(公告)日：2014-05-27

    申请号：US13242541

    申请日：2011-09-23

    申请人： Nobuo Cho ,  Takashi Imada ,  Takenori Hitaka ,  Kazuhiro Miwa ,  Masami Kusuka ,  Nobuhiro Suzuki

    发明人： Nobuo Cho ,  Takashi Imada ,  Takenori Hitaka ,  Kazuhiro Miwa ,  Masami Kusuka ,  Nobuhiro Suzuki

    IPC分类号： A61K31/519 ,  A61P35/04 ,  C07D495/04

    CPC分类号： C07D495/04 ,  A61K31/519

    摘要： The present invention provides a compound represented by the formula: wherein R1 is a C1-4 alkyl; R2 is (1) a 5- to 7-membered nitrogen-containing heterocyclic group which may have a substituent selected from the group consisting of (1′) a halogen, (2′) a hydroxy group, (3′) a C1-4 alkyl and (4′) a C1-4 alkoxy, (2) a phenyl which may have a substituent selected from the group consisting of (1′) a halogen, (2′) a C1-4 alkoxy-C1-4 alkyl, (3′) a mono-C1-4 alkyl-carbamoyl-C1-4 alkyl, (4′) a C1-4 alkoxy and (5′) a mono-C1-4 alkylcarbamoyl-C1-4 alkoxy, or the like; R3 is a C1-4 alkyl; R4 is a C1-4 alkoxy, or the like; n is an integer of 1 to 4; or a salt thereof, as a thienopyrimidine compound having gonadotropin-releasing hormone antagonistic activity.

    摘要翻译： 本发明提供由下式表示的化合物：其中R1是C1-4烷基; R2是（1）可以具有选自（1'）卤素，（2'）羟基，（3'），C 1〜C 6的取代基的5〜7元含氮杂环基， 4烷基和（4'）C 1-4烷氧基，（2）可具有选自（1'）卤素，（2'）C 1-4烷氧基-C 1-4烷基的取代基的苯基 ，（3'）单-C 1-4烷基 - 氨基甲酰基-C 1-4烷基，（4'）C 1-4烷氧基和（5'）单-C 1-4烷基氨基甲酰基-C 1-4烷氧基等 ; R3是C1-4烷基; R4是C1-4烷氧基等; n为1〜4的整数， 或其盐作为具有促性腺激素释放激素拮抗活性的噻吩并嘧啶化合物。

    Speed Change Control System for Industrial Vehicle
    5.
    发明申请
    Speed Change Control System for Industrial Vehicle 有权
    工业车辆变速控制系统

    公开(公告)号：US20100071987A1

    公开(公告)日：2010-03-25

    申请号：US12516965

    申请日：2007-11-30

    申请人： Koji Hyodo ,  Tetsuji Tanaka ,  Eiichi Sakai ,  Nobuhiro Suzuki ,  Koji Takano

    发明人： Koji Hyodo ,  Tetsuji Tanaka ,  Eiichi Sakai ,  Nobuhiro Suzuki ,  Koji Takano

    IPC分类号： F16H61/00 ,  G06F19/00

    CPC分类号： F16H61/0213 ,  E02F9/2079 ,  E02F9/2083 ,  E02F9/2253 ,  F16H59/44 ,  F16H59/68 ,  F16H2059/467 ,  Y10T477/60 ,  Y10T477/62427 ,  Y10T477/6934

    摘要： A speed change control system for an industrial vehicle includes: a speed ratio detecting unit that detects a speed ratio of speeds of an input shaft and of an output shaft of a torque converter; a torque converter speed ratio-based speed changer that shifts up or shifts down a speed stage of a transmission 3 in response to the detected speed ratio; a vehicle speed detection unit that detects a speed of the vehicle; a mode selection unit that selects any one of an L-mode and an H-mode; and a speed change control unit that permits an upshift provided that the vehicle speed is equal to or higher than a first predetermined value when the L-mode is selected whereas permits the upshift provided that the vehicle speed is higher than another predetermined value which is larger that the predetermined value when the H-mode is selected.

    摘要翻译： 一种用于工业车辆的变速控制系统包括：速比检测单元，其检测变矩器的输入轴和输出轴的速度的速度比; 基于变速器速比的变速器，其响应于所检测的速比而向变速器3的转速级向上或向下移动; 车速检测单元，其检测车辆的速度; 模式选择单元，其选择L模式和H模式中的任一个; 以及变速控制单元，其允许升档，条件是当选择L模式时，车速等于或高于第一预定值，而允许升档，只要车速高于另一个较大的预定值 选择H模式时的预定值。

    THIENOPYRIMIDINE COMPOUNDS AND USE THEREOF
    7.
    发明申请
    THIENOPYRIMIDINE COMPOUNDS AND USE THEREOF 有权
    噻吗啉化合物及其用途

    公开(公告)号：US20080108623A1

    公开(公告)日：2008-05-08

    申请号：US11848939

    申请日：2007-08-31

    申请人： Nobuo Cho ,  Takashi Imada ,  Takenori Hitaka ,  Kazuhiro Miwa ,  Masami Kusaka ,  Nobuhiro Suzuki

    发明人： Nobuo Cho ,  Takashi Imada ,  Takenori Hitaka ,  Kazuhiro Miwa ,  Masami Kusaka ,  Nobuhiro Suzuki

    IPC分类号： A61K31/495 ,  A61K31/519 ,  C07D495/04 ,  C07D401/02 ,  A61P5/04

    CPC分类号： C07D495/04 ,  A61K31/519

    摘要： The present invention provides a compound represented by the formula: wherein R1 is a C1-4 alkyl; R2 is (1) a 5- to 7-membered nitrogen-containing heterocyclic group which may have a substituent selected from the group consisting of (1′) a halogen, (2′) a hydroxy group, (3′) a C1-4 alkyl and (4′) a C1-4 alkoxy, (2) a phenyl which may have a substituent selected from the group consisting of (1′) a halogen, (2′) a C1-4 alkoxy-C1-4 alkyl, (3′) a mono-C1-4 alkyl-carbamoyl-C1-4 alkyl, (4′) a C1-4 alkoxy and (5′) a mono-C1-4 alkylcarbamoyl-C1-4 alkoxy, or the like; R3 is a C1-4 alkyl; R4 is a C1-4 alkoxy, or the like; n is an integer of 1 to 4; or a salt thereof, as a thienopyrimidine compound having gonadotropin-releasing hormone antagonistic activity.

    摘要翻译： 本发明提供由下式表示的化合物：其中R 1是C 1-4烷基; R 2是（1）可以具有选自（1'）卤素，（2'）羟基的取代基的5-至7-元含氮杂环基 ，（3'）C 1-4烷基和（4'）C 1-4烷氧基，（2）可以具有选自以下的取代基的苯基： （1'）卤素，（2'），C 1-4烷氧基-C 1-4烷基，（3'）单-C 烷基 - 氨基甲酰基-C 1-4烷基，（4'）C 1-4烷氧基和（5'）单 -C 1-4烷基氨基甲酰基-C 1-4烷氧基等; R 3是C 1-4烷基; R 4是C 1-4烷氧基等; n为1〜4的整数， 或其盐作为具有促性腺激素释放激素拮抗活性的噻吩并嘧啶化合物。

    Quinoline compound
    9.
    发明授权
    Quinoline compound 失效
    喹啉化合物

    公开(公告)号：US07183415B2

    公开(公告)日：2007-02-27

    申请号：US10493427

    申请日：2002-10-24

    申请人： Yuji Ishihara ,  Makoto Kamata ,  Shiro Takekawa ,  Nobuhiro Suzuki ,  Koki Kato

    发明人： Yuji Ishihara ,  Makoto Kamata ,  Shiro Takekawa ,  Nobuhiro Suzuki ,  Koki Kato

    IPC分类号： C07D215/38 ,  C07D215/14

    CPC分类号： C07D401/06 ,  A61K31/47 ,  A61K31/4709 ,  A61K31/496 ,  A61K31/5377 ,  A61K31/55 ,  C07D215/38 ,  C07D401/12 ,  C07D405/12 ,  C07D409/12 ,  C07D471/04

    摘要： A compound, which has a melanin-concentrating hormone antagonistic action and useful as an agent for preventing or treating obesity, and which is represented by the formula: wherein Ar is a cyclic group optionally having substituent(s); X is a bond or a spacer having a main chain of 1 to 6 atoms; R1 and R2 are the same or different and each is a hydrogen atom or a hydrocarbon group optionally having substituent(s), or R1 and R2 may form, together with the adjacent nitrogen atom, a nitrogen-containing heterocycle optionally having substituent(s); Y is a divalent hydrocarbon group optionally having substituent(s) (except CO); R3 is a hydrogen atom or a hydrocarbon group optionally having substituent(s); and ring A and ring B may further have substituents, and when ring B further has a substituent, the substituent may be linked to R1 to form a ring, or a salt thereof, or a prodrug thereof, is provided.

    摘要翻译： 一种化合物，其具有黑色素浓集激素拮抗作用并且可用作预防或治疗肥胖症的药剂，并且其由下式表示：其中Ar是任选具有取代基的环状基团; X是具有1至6个原子的主链的键或间隔基; R 1和R 2相同或不同，各自为氢原子或任选具有取代基的烃基，或R 1〜 >和R 2可以与相邻的氮原子一起形成任选具有取代基的含氮杂环; Y是任选具有取代基（CO除外）的二价烃基; R 3是氢原子或任选具有取代基的烃基; 并且环A和环B可以进一步具有取代基，并且当环B还具有取代基时，取代基可以与R 1连接形成环，或其盐或其前药， 被提供。