摘要:
A cathode-ray tube apparatus capable of reducing a high frequency electric field radiated from the deflection yoke and the deflection and high voltage circuit to the outside of the cathode-ray tube apparatus. Mounted on the deflection yoke or on the cathode-ray tube are an induction coil for generating a pulse voltage opposite in polarity to a high pulse voltage applied to the h and an electric field cancellation electrode made of a conductive wire to which the opposite polarity pulse voltage is applied. When the opposite polarity pulse voltage is applied to the electric field cancellation electrode, the electric field cancellation electrode radiates an electric field opposite in polarity to the high frequency electric field radiated from the deflection yoke to the outside of the cathode-ray tube apparatus to reduce the intensity of the high frequency electric field.
摘要:
A cathode-ray tube apparatus capable of reducing a high frequency electric field radiated from the deflection yoke and the deflection and high voltage circuit to the outside of the cathode-ray tube apparatus. Mounted on the deflection yoke or on the cathode-ray tube are an induction coil for generating a pulse voltage opposite in polarity to a high pulse voltage applied to the h and an electric field cancellation electrode made of a conductive wire to which the opposite polarity pulse voltage is applied. When the opposite polarity pulse voltage is applied to the electric field cancellation electrode, the electric field cancellation electrode radiates an electric field opposite in polarity to the high frequency electric field radiated from the deflection yoke to the outside of the cathode-ray tube apparatus to reduce the intensity of the high frequency electric field.
摘要:
A deflection yoke having cancelling loop coils for reducing undesired portions of a horizontal deflection magnetic field generated by a deflection yoke body without mislanding. The cancelling loop coils generate a cancelling magnetic field which includes two peaks in a front region and a rear region of the deflection yoke body in which the undesired field portions exist, respectively. The peaks are opposite in direction to the horizontal magnetic field generated by the deflection yoke body, respectively, with same ratio to the deflection magnetic field, so that the undesired magnetic field portions are under-corrected in the front portion and over-corrected in the rear portion.
摘要:
A compound represented by the general formula (I), a pharmaceutically acceptable acid addition salt thereof or a pharmaceutically acceptable C1-C6 alkyl addition salt thereof, and their medical applications. These compounds inhibit the action of chemokines such as MIP-1&agr; and/or MCP-1 on target cells, and are useful as therapeutic and/or preventative drugs in diseases, such as atherosclerosis, rheumatoid arthritis, and the like where blood monocytes and lymphocytes infiltrate into tissues.
摘要:
Specific optically active 4- hydroxy-2-cyclopentenone derivatives and mixtures thereof having the formula (I): ##STR1## and an anticancer-agent and a bone formation accelerator containing the same as effective active ingredients.
摘要:
The present invention provides a method of searching for a target molecule for a ligand immobilized on a metal surface or analyzing the interaction between a ligand and a target molecule, characterized in that the immobilization of the ligand on the metal surface via a hydrophilic spacers, and the method eliminates or suppresses a nonspecific interaction that prevents analysis of intermolecular interaction on a metal surface, and can intensify specific intermolecular interactions.
摘要:
A compound represented by the general formula (I), a pharmaceutically acceptable acid addition salt thereof or a pharmaceutically acceptable C1-C6 alkyl addition salt thereof, and their medical applications. These compounds inhibit the action of chemokines such as MIP-1&agr; and/or MCP-1 on target cells, and are useful as therapeutic and/or preventative drugs in diseases, such as atherosclerosis, rheumatoid arthritis, and the like where blood monocytes and lymphocytes infiltrate into tissues.
摘要:
The present invention is intended to elucidate a molecular target of an antidiabetic such as a thiazolidine derivative. The present invention provides a screening method for an antidiabetic, comprising the steps of: bringing a candidate substance to be screened into contact with a protein represented by the following (a) or (b): (a) a protein comprising the amino acid sequence represented by SEQ ID NO: 2; or (b) a protein comprising an amino acid sequence derived from the amino acid sequence represented by SEQ ID NO: 2 with the deletion, substitution, addition, or insertion of one or plural amino acids and interacting with the antidiabetic; and detecting the interaction between the candidate substance and the protein.
摘要翻译:本发明旨在阐明抗糖尿病药如噻唑烷衍生物的分子靶标。 本发明提供一种抗糖尿病的筛选方法,其特征在于,包括以下步骤:使候选物质与下列(a)或(b)所示蛋白质接触:(a)含有氨基酸序列 由SEQ ID NO:2表示; 或者(b)包含来源于SEQ ID NO:2所示的氨基酸序列的氨基酸序列的蛋白质与一个或多个氨基酸的缺失,取代,添加或插入并与抗糖尿病相互作用的蛋白质; 并检测候选物质与蛋白质之间的相互作用。
摘要:
A compound represented by the general formula (I), a pharmaceutically acceptable acid addition salt thereof or a pharmaceutically acceptable C1-C6 alkyl addition salt thereof, and their medical applications. These compounds inhibit the action of chemokines such as MIP-1&agr; and/or MCP-1 on target cells, and are useful as therapeutic and/or preventative drugs in diseases, such as atheroclerosis, rheumatoid arthritis, and the like where blood monocytes and lymphocytes infiltrate into tissues.
摘要:
The present invention provides a method of suppressing the nonspecific interaction between molecules, characterized in that in a process to immobilize a molecule onto a solid phase carrier and analyze the specific interaction between the molecule and a molecule that specifically interacts with the molecule on the solid phase, the hydrophobic property of the solid phase surface in the solid phase carrier is regulated, particularly a hydrophilic spacer is interlaid at the time of immobilization of the molecule onto the solid phase carrier, which method makes it possible to suppress the nonspecific interaction between the molecules, and to reduce nonspecific adsorption to the solid phase.