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    Methods and reagents for discovering and using mammalian melanocortin receptor agonists and antagonists to modulate feeding behavior in animals
    1.
    发明授权
    Methods and reagents for discovering and using mammalian melanocortin receptor agonists and antagonists to modulate feeding behavior in animals 失效
    用于发现和使用哺乳动物黑皮质素受体激动剂和拮抗剂调节动物饲养行为的方法和试剂

    公开(公告)号：US06476187B1

    公开(公告)日：2002-11-05

    申请号：US09353099

    申请日：1999-07-14

    申请人： Roger D. Cone ,  Wei Fan ,  Bruce A. Boston ,  Robert A. Kesterton ,  Dongsi Lu ,  Wenbiao Chen

    发明人： Roger D. Cone ,  Wei Fan ,  Bruce A. Boston ,  Robert A. Kesterton ,  Dongsi Lu ,  Wenbiao Chen

    IPC分类号： A61K3800

    CPC分类号： C07K14/72 ,  A61K38/00 ,  C07K7/56 ,  C07K14/723 ,  C12Q1/6876 ,  C12Q1/6886 ,  C12Q1/6897 ,  C12Q2600/136 ,  G01N33/74 ,  G01N2333/68 ,  G01N2333/695 ,  G01N2333/72 ,  G01N2333/726 ,  G01N2500/00

    摘要： The present invention provides recombinant expression constructs comprising nucleic acid encoding mammalian melanocortin receptors, and mammalian cells into which said recombinant expression constructs have been introduced that express functional mammalian melanocortin receptors. The invention provides a panel of such transformed mammalian cells expressing melanocortin receptors for screening compounds for receptor agonist and antagonist activity. The invention also provides methods for using such panels of melanocortin receptor-expressing mammalian cells to specifically-detect and identify agonists and antagonists for each melanocortin receptor, as well as patterns of agonist and antagonist activity of said compounds for the class of melanocortin receptors. Such screening methods provide a means for identifying compounds with patterns of melanocortin agonist and antagonist activity which is associated with the capacity to influence or modify metabolism and behavior, particularly feeding behavior.

    摘要翻译： 本发明提供包含编码哺乳动物黑皮质素受体的核酸的重组表达构建体和已经引入表达功能性哺乳动物黑皮质素受体的所述重组表达构建体的哺乳动物细胞。 本发明提供了一组这样的转化的哺乳动物细胞，其表达用于筛选受体激动剂和拮抗剂活性的化合物的黑皮质素受体。 本发明还提供了使用这样的黑皮质素受体表达哺乳动物细胞的这种面板来特异性检测和鉴定每种黑皮质素受体的激动剂和拮抗剂的方法，以及所述化合物对黑皮质素受体类型的激动剂和拮抗剂活性的模式。 这种筛选方法提供用于鉴定与影响或修饰代谢和行为，特别是进食行为的能力相关的黑皮质素激动剂和拮抗剂活性的化合物的方法。

    CHARGE SHARING SYSTEM AND METHOD OF LCOS DISPLAY
    4.
    发明申请
    CHARGE SHARING SYSTEM AND METHOD OF LCOS DISPLAY 审中-公开
    充电共享系统和LCOS显示方法

    公开(公告)号：US20120050245A1

    公开(公告)日：2012-03-01

    申请号：US13265447

    申请日：2010-09-16

    申请人： Yongping Dai ,  Xuhuai Dong ,  Wei Fan ,  Yi Fan

    发明人： Yongping Dai ,  Xuhuai Dong ,  Wei Fan ,  Yi Fan

    IPC分类号： G09G3/36 ,  G06F3/038

    CPC分类号： G09G3/3688 ,  G09G2310/0248 ,  G09G2330/021

    摘要： In the field of a liquid crystal on silicon (LCoS) display, a charge sharing system and a charge sharing method of an LCoS display are provided. The system includes: a column driving circuit, a row driving circuit, a pixel matrix, a control circuit, a gamma reference voltage circuit, and a first switching module. The column driving circuit includes a second switching module, a buffer, a shift register, a latch, and a digital-to-analog (D/A) converter. The second switching module is serially connected between the D/A converter and the buffer. The control circuit simultaneously outputs a signal for controlling turn-off of the buffer, a signal for controlling turn-off of a switch in the second switching module, and a signal for controlling turn-off of the gamma reference voltage circuit. The control circuit outputs a signal for controlling turn-on of a switch in the first switching module. The control circuit outputs a signal for controlling the row driving circuit. The control circuit simultaneously outputs a signal for controlling turn-on of the buffer, a signal for controlling turn-on of the switch in the second switching module, and a signal for controlling turn-on of the gamma reference voltage circuit.

    摘要翻译： 在液晶硅（LCoS）显示领域，提供LCoS显示的电荷共享系统和电荷共享方法。 该系统包括：列驱动电路，行驱动电路，像素矩阵，控制电路，伽马参考电压电路和第一开关模块。 列驱动电路包括第二开关模块，缓冲器，移位寄存器，锁存器和数模（D / A）转换器。 第二开关模块串联连接在D / A转换器和缓冲器之间。 控制电路同时输出用于控制缓冲器的关断的信号，用于控制第二开关模块中的开关的关断的信号和用于控制伽马参考电压电路的关断的信号。 控制电路输出用于控制第一开关模块中的开关的接通的信号。 控制电路输出用于控制行驱动电路的信号。 控制电路同时输出用于控制缓冲器的接通的信号，用于控制第二开关模块中的开关的导通的信号和用于控制伽马参考电压电路的导通的信号。

    Method and system for predicting resource usage of reusable stream processing elements
    5.
    发明授权
    Method and system for predicting resource usage of reusable stream processing elements 有权
    用于预测可重用流处理元素资源使用的方法和系统

    公开(公告)号：US07941387B2

    公开(公告)日：2011-05-10

    申请号：US11935079

    申请日：2007-11-05

    申请人： Lisa Amini ,  Henrique Andrade ,  Wei Fan ,  James R. Giles ,  Kirsten W. Hildrum ,  Deepak Rajan ,  Deepak S. Turaga ,  Rohit Wagle ,  Joel L. Wolf ,  Philip S. Yu

    发明人： Lisa Amini ,  Henrique Andrade ,  Wei Fan ,  James R. Giles ,  Kirsten W. Hildrum ,  Deepak Rajan ,  Deepak S. Turaga ,  Rohit Wagle ,  Joel L. Wolf ,  Philip S. Yu

    IPC分类号： G06F17/00 ,  G06N5/02

    CPC分类号： G06N99/005

    摘要： A method is provided for generating a resource function estimate of resource usage by an instance of a processing element configured to consume zero or more input data streams in a stream processing system having a set of available resources that comprises receiving at least one specified performance metric for the zero or more input data streams and a processing power of the set of available resources, wherein one specified performance metric is stream rate; generating a multi-part signature of executable-specific information for the processing element and a multi-part signature of context-specific information for the instance; accessing a database of resource functions to identify a static resource function corresponding to the executable-specific information and a context-dependent resource function corresponding to the context-specific information; combining the static resource function and the context-dependent resource function to form a composite resource function for the instance; and applying the resource function to the at least one specified performance metric and the processing power to generate the resource function estimate of the at least one specified performance metric for processing by the instance.

    摘要翻译： 提供了一种用于通过被配置为在具有一组可用资源的流处理系统中消耗零个或多个输入数据流的处理元件的实例来生成资源使用的资源功能估计的方法，所述流处理系统包括：一组可用资源，其包括接收至少一个指定的性能度量 零个或多个输入数据流和可用资源集合的处理能力，其中一个指定的性能度量是流速率; 生成用于处理元件的可执行特定信息的多部分签名和该实例的上下文特定信息的多部分签名; 访问资源功能的数据库以识别与所述可执行特定信息相对应的静态资源功能以及与所述上下文特定信息相对应的与上下文相关的资源功能; 结合静态资源功能和上下文相关资源功能，形成实例的复合资源功能; 以及将所述资源功能应用于所述至少一个指定的性能度量和所述处理能力，以生成所述至少一个指定的性能度量的资源功能估计，以供所述实例处理。

    Heating apparatus with enhanced thermal uniformity and method for making thereof
    6.
    发明授权
    Heating apparatus with enhanced thermal uniformity and method for making thereof 有权
    具有增强的热均匀性的加热装置及其制造方法

    公开(公告)号：US07901509B2

    公开(公告)日：2011-03-08

    申请号：US11549968

    申请日：2006-10-16

    申请人： John Mariner ,  Ajit Sane ,  Toshiki Ebata ,  Marc Schaepkens ,  Xiang Liu ,  Wei Fan

    发明人： John Mariner ,  Ajit Sane ,  Toshiki Ebata ,  Marc Schaepkens ,  Xiang Liu ,  Wei Fan

    IPC分类号： C23C16/00 ,  H01L21/306

    CPC分类号： C23C16/4586 ,  H01L21/67103

    摘要： A heating apparatus for regulating/controlling the surface temperature of a substrate is provided. At least a thermal pyrolytic graphite (TPG) layer is embedded in the heater to diffuse the temperature difference of the various components in the heating apparatus and provide temporal and spatial control of the surface temperature of the substrate, for a relatively uniform substrate temperature with the difference between the maximum and minimum temperature points on the substrate of less than 10° C.

    摘要翻译： 提供一种用于调节/控制基板的表面温度的加热装置。 至少一个热解石墨（TPG）层被嵌入在加热器中以扩散加热装置中的各种组分的温度差，并提供衬底的表面温度的时间和空间控制，对于相对均匀的衬底温度， 基板上最大和最小温度点之间的差值小于10°C

    SELF-POWERED IN-PIPE FLUID METER AND PIPING NETWORK COMPRISING A PLURALITY OF SUCH FLUID METERS
    7.
    发明申请
    SELF-POWERED IN-PIPE FLUID METER AND PIPING NETWORK COMPRISING A PLURALITY OF SUCH FLUID METERS 失效
    自供电的管内流量计和包含这种流量计的多重流量的管网

    公开(公告)号：US20100085211A1

    公开(公告)日：2010-04-08

    申请号：US12376733

    申请日：2007-08-06

    申请人： Zhenfeng Wang ,  Ser Yong Lim ,  Wei Fan ,  Danhong Zhang

    发明人： Zhenfeng Wang ,  Ser Yong Lim ,  Wei Fan ,  Danhong Zhang

    IPC分类号： G08B1/00

    CPC分类号： G01N33/18 ,  G01F1/10 ,  G01F15/063

    摘要： A self-powered in-pipe fluid meter to be mounted inside of a pipe carrying a fluid therein. The fluid meter comprises at least one sensing unit capable of measuring one or more parameters of the fluid inside of the pipe; a telemetric data transmission unit capable of telemetrically transmitting data including a measured fluid parameter to a host terminal and/or another fluid meter; and at least one fluid-driven power source unit capable of generating power from the fluid flow within the pipe and supplying power to the sensing unit and/or the transmission unit.

    摘要翻译： 一种自供电的管内流量计，安装在其中携带流体的管道的内部。 所述流量计包括能够测量所述管内部的流体的一个或多个参数的至少一个传感单元; 遥测数据传输单元，其能够将包括测量的流体参数的数据遥测地传送到主机终端和/或另一个流量计; 以及至少一个流体驱动的电源单元，其能够从管道内的流体流产生功率，并向感测单元和/或传输单元供电。

    METHOD AND APPARATUS FOR STRUCTURAL DATA CLASSIFICATION
    8.
    发明申请
    METHOD AND APPARATUS FOR STRUCTURAL DATA CLASSIFICATION 有权
    用于结构数据分类的方法和装置

    公开(公告)号：US20090319457A1

    公开(公告)日：2009-12-24

    申请号：US12141251

    申请日：2008-06-18

    申请人： Hong Cheng ,  Wei Fan ,  Xifeng Yan ,  Philip Shi-lung Yu

    发明人： Hong Cheng ,  Wei Fan ,  Xifeng Yan ,  Philip Shi-lung Yu

    IPC分类号： G06N5/02

    CPC分类号： G06N99/005

    摘要： Techniques for classifying structural data with skewed distribution are disclosed. By way of example, a method classifying structural input data comprises a computer system performing the following steps. Multiple classifiers are constructed, wherein each classifier is constructed on a subset of training data, using one or more selected composite features from the subset of training data. A consensus among the multiple classifiers is computed in accordance with a voting scheme such that at least a portion of the structural input data is assigned to a particular class in accordance with the computed consensus. Such techniques for structured data classification are capable of handling skewed class distribution and partial feature coverage issues.

    摘要翻译： 公开了分布具有偏斜分布的结构数据的技术。 作为示例，分类结构输入数据的方法包括执行以下步骤的计算机系统。 构建多个分类器，其中使用来自训练数据的子集的一个或多个选定的复合特征，在训练数据的子集上构建每个分类器。 根据投票方案计算多个分类器之间的共识，使得至少一部分结构输入数据根据所计算的一致性被分配给特定类别。 这种用于结构化数据分类的技术能够处理倾斜的类分布和部分特征覆盖问题。

    Optimized auction commodity distribution system, method, and computer program product
    9.
    发明授权
    Optimized auction commodity distribution system, method, and computer program product 有权
    优化拍卖商品分销系统，方法和计算机程序产品

    公开(公告)号：US07636675B1

    公开(公告)日：2009-12-22

    申请号：US10632799

    申请日：2003-08-04

    申请人： Jie Cheng ,  Jie Du ,  Wei Fan

    发明人： Jie Cheng ,  Jie Du ,  Wei Fan

    IPC分类号： G06Q30/00

    CPC分类号： G06Q10/04 ,  G06Q30/08

    摘要： A commodity product distribution plan is used to instruct source sites as to how commodity products are to be distributed among target sites. Where the commodity products are to be sold at auction, a wide range of auction prices can be expected due to mixed models, model years, commodity attributes such as color or optional features, economic conditions, and the auction site location itself. Additional factors that contribute to realized auction prices include depreciation and interest rate costs as well as constraints on shipments and auction site capacities. The present invention provides forecast auction prices for the commodity products, taking these various factors into consideration. In this way, an optimized distribution planned aimed at maximizing the potential profit for the commodity products to be sold at auction is generated.

    摘要翻译： 商品产品分配计划用于指示源站点如何在目标站点之间分发商品产品。 如果商品在拍卖会上出售，由于混合模型，模特年份，颜色或可选特征，经济条件和拍卖地点本身等商品属性，可以预期拍卖价格范围广泛。 促成实现拍卖价格的其他因素包括折旧和利率成本以及出货和拍卖现场能力的限制。 本发明提供了商品的预测拍卖价格，并考虑了这些因素。 这样就可以产生一个优化的分销计划，旨在最大限度地提高在拍卖会上出售的商品的潜在利润。

    System and method for mining time-changing data streams
    10.
    发明授权
    System and method for mining time-changing data streams 有权
    挖掘时变数据流的系统和方法

    公开(公告)号：US07565369B2

    公开(公告)日：2009-07-21

    申请号：US10857030

    申请日：2004-05-28

    申请人： Wei Fan ,  Haixun Wang ,  Philip S. Yu

    发明人： Wei Fan ,  Haixun Wang ,  Philip S. Yu

    IPC分类号： G06F17/30

    CPC分类号： G06N99/005 ,  Y10S707/99943 ,  Y10S707/99945

    摘要： A general framework for mining concept-drifting data streams using weighted ensemble classifiers. An ensemble of classification models, such as C4.5, RIPPER, naive Bayesian, etc., is trained from sequential chunks of the data stream. The classifiers in the ensemble are judiciously weighted based on their expected classification accuracy on the test data under the time-evolving environment. Thus, the ensemble approach improves both the efficiency in learning the model and the accuracy in performing classification. An empirical study shows that the proposed methods have substantial advantage over single-classifier approaches in prediction accuracy, and the ensemble framework is effective for a variety of classification models.

    摘要翻译： 采用加权综合分类器挖掘概念漂移数据流的一般框架。 分类模型的集合，例如C4.5，RIPPER，朴素贝叶斯等，是从数据流的连续块中训练出来的。 根据其在时间不断变化的环境下的测试数据的预期分类精度，合理地加权集合中的分类器。 因此，综合方法提高了学习模型的效率和执行分类的准确性。 实证研究表明，所提出的方法在预测精度方面具有优于单分类器方法的优势，并且整体框架对于各种分类模型是有效的。