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    Implantable stimulator that prevents DC current flow without the use of discrete output coupling capacitors
    4.
    发明授权
    Implantable stimulator that prevents DC current flow without the use of discrete output coupling capacitors 失效
    可植入式刺激器，可防止直流电流流动而不使用离散输出耦合电容

    公开(公告)号：US06035237A

    公开(公告)日：2000-03-07

    申请号：US447455

    申请日：1995-05-23

    申请人： Joseph H. Schulman ,  Alfred E. Mann ,  John C. Gord ,  Ronald J. Lebel

    发明人： Joseph H. Schulman ,  Alfred E. Mann ,  John C. Gord ,  Ronald J. Lebel

    IPC分类号： A61N1/08 ,  A61N1/32 ,  A61N1/36 ,  A61N1/16

    CPC分类号： A61N1/36142 ,  A61N1/36125

    摘要： An implantable living tissue stimulator avoids the use of conventional coupling capacitors in its output stage, yet still prevents an average dc current flow from flowing through living tissue in electrical contact with the stimulator. The output stage generates and applies a biphasic stimulating current pulse to selected paired output terminals. The terminals, in turn, are electrically connected to respective electrodes which are positioned so as to contact the living tissue to be stimulated. In one embodiment, special circuitry is employed within the output stage to block dc current flow through the living tissue and to balance the electrical charge that is delivered to the living tissue. In another embodiment, the electrodes themselves are made from a material that allows them to function as a capacitor. In yet an additional embodiment, the coupling capacitors are integrated into the leads that connect the output terminals of the output stage with the electrodes.

    摘要翻译： 植入式生物组织刺激器避免了在其输出阶段使用传统的耦合电容器，但仍然阻止平均直流电流流过活组织与刺激器电接触。 输出级产生并将双相刺激电流脉冲施加到选定的配对输出端子。 这些端子又电连接到相应的电极，这些电极定位成接触待刺激的生物体组织。 在一个实施例中，在输出级内采用特殊电路来阻止直流电流流过活组织并平衡输送到生物体组织的电荷。 在另一个实施例中，电极本身由允许它们用作电容器的材料制成。 在又一个实施例中，耦合电容器集成到将输出级的输出端与电极连接的引线中。

    Implantable substrate sensor with back-to-back electrodes
    6.
    发明授权
    Implantable substrate sensor with back-to-back electrodes 有权
    具有背对背电极的可植入衬底传感器

    公开(公告)号：US07555328B2

    公开(公告)日：2009-06-30

    申请号：US11392163

    申请日：2006-03-29

    申请人： Joseph H. Schulman ,  Charles L. Byers ,  John C. Gord ,  Rajiv Shah ,  Lyle Dean Canfield

    发明人： Joseph H. Schulman ,  Charles L. Byers ,  John C. Gord ,  Rajiv Shah ,  Lyle Dean Canfield

    IPC分类号： A61B5/145

    CPC分类号： A61N1/36585 ,  A61B5/0031 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/14865 ,  A61B5/4839 ,  A61B2560/0219 ,  A61M5/1723 ,  A61N1/05 ,  A61N1/372 ,  A61N1/3754 ,  H01L23/3107 ,  H01L29/0657 ,  H01L2924/0002 ,  H01L2924/19041 ,  H01L2924/00

    摘要： An implantable substrate sensor has electronic circuitry and electrodes formed on opposite sides of a substrate. A protective coating covers the substrate, effectively hermetically sealing the electronic circuitry under the coating. Exposed areas of the electrodes are selectively left uncovered by the protective coating, thereby allowing such electrodes to be exposed to body tissue and fluids when the sensor is implanted in living tissue. The substrate on which the electronic circuitry and electrodes are formed is the same substrate or “chip” on which an integrated circuit (IC) is formed, which integrated circuit contains the desired electronic circuitry. Such approach eliminates the need for an hermetically sealed lid or cover to cover hybrid electronic circuitry, and allows the sensor to be made much thinner than would otherwise be possible. In one embodiment, two such substrate sensor may be placed back-to-back, with the electrodes facing outward. As required, capacitors that form part of the sensor's electronic circuits are formed on the substrate by placing metalization layers and a dielectric in vacant areas of the substrate surface.

    摘要翻译： 可植入衬底传感器具有形成在衬底的相对侧上的电子电路和电极。 保护涂层覆盖基材，有效地气密地密封涂层下的电子电路。 电极的暴露区域选择性地被保护涂层覆盖，从而当传感器植入生物体组织时允许这样的电极暴露于身体组织和流体。 其上形成有电子电路和电极的基板是与其上形成有集成电路（IC）的相同的基板或“芯片”，该集成电路包含所需的电子电路。 这种方法消除了密封的盖或盖以覆盖混合电子电路的需要，并且允许传感器制造得比其他可能的薄得多。 在一个实施例中，两个这样的衬底传感器可以背靠背放置，电极面向外。 根据需要，通过将金属化层和电介质放置在基板表面的空的区域中，形成在传感器的电子电路的一部分的电容器。

    Fully implantable cochlear implant system
    7.
    发明授权
    Fully implantable cochlear implant system 有权
    完全植入式耳蜗植入系统

    公开(公告)号：US06308101B1

    公开(公告)日：2001-10-23

    申请号：US09404966

    申请日：1999-09-24

    申请人： Michael A. Faltys ,  Janusz A. Kuzma ,  John C. Gord

    发明人： Michael A. Faltys ,  Janusz A. Kuzma ,  John C. Gord

    IPC分类号： A61N136

    CPC分类号： A61N1/08 ,  A61N1/36036 ,  A61N1/375 ,  A61N1/3787

    摘要： A fully implantable cochlear implant system (170) and method includes an implantable cochlear stimulator (ICS) unit (212) that is connected to an implantable speech processor (ISP) unit (210). Both the ISP unit and the ICS unit reside in separate, hermetically-sealed, cases. The ICS unit has a coil (220) permanently connected thereto through which magnetic or inductive coupling may occur with a similar coil located externally during recharging, programming, or externally-controlled modes of operation. The ICS unit further has a cochlear electrode array (114) permanently connected thereto via a first multi-conductor cable (116). The ICS unit 212 also has a second multi-conductor cable (222) attached thereto, which second cable contains no more than five conductors. The second cable is detachably connected to the ISP unit via a connector (224) located on the case of the ISP unit. The ISP unit includes an implantable subcutaneous microphone (218) as an integral part thereof, and further includes ISP circuitry (214) and a replenishable power source (216), e.g., a rechargeable battery.

    摘要翻译： 完全植入式人工耳蜗植入系统（170）和方法包括连接到可植入语音处理器（ISP）单元（210）的可植入人工耳蜗刺激器（ICS）单元（212）。 ISP单元和ICS单元均位于单独的密封的情况下。 ICS单元具有永久连接到其上的线圈（220），通过该线圈可以在再充电，编程或外部控制的操作模式期间与位于外部的类似线圈发生磁耦合或电感耦合。 ICS单元还具有经由第一多导体电缆（116）永久地连接到其上的耳蜗电极阵列（114）。 ICS单元212还具有附接到其上的第二多导体电缆（222），该第二电缆包含不超过五个导体。 第二电缆通过位于ISP单元壳体上的连接器（224）可拆卸地连接到ISP单元。 ISP单元包括可植入式皮下麦克风（218）作为其整体部分，并且还包括ISP电路（214）和可补充电源（216），例如可再充电电池。

    System of implantable devices for monitoring and/or affecting body parameters
    8.
    发明授权
    System of implantable devices for monitoring and/or affecting body parameters 失效
    用于监测和/或影响身体参数的可植入装置的系统

    公开(公告)号：US6164284A

    公开(公告)日：2000-12-26

    申请号：US48827

    申请日：1998-03-25

    申请人： Joseph H. Schulman ,  Robert Dan Dell ,  John C. Gord

    发明人： Joseph H. Schulman ,  Robert Dan Dell ,  John C. Gord

    IPC分类号： A61B5/00 ,  A61B5/053 ,  A61B5/07 ,  A61B19/00 ,  A61F2/50 ,  A61F2/70 ,  A61F2/72 ,  A61N1/372 ,  A61N1/378

    CPC分类号： A61N1/37211 ,  A61B5/0031 ,  A61B5/053 ,  A61B5/07 ,  A61B5/145 ,  A61B5/14532 ,  A61B5/4519 ,  A61B5/4528 ,  A61B2560/0219 ,  A61B2562/08 ,  A61F2/72 ,  A61F2002/5058 ,  A61F2002/704 ,  A61F2002/705 ,  A61N1/37205 ,  A61N1/37252 ,  A61N1/37288 ,  A61N1/3787

    摘要： A system for monitoring and/or affecting parameters of a patient's body and more particularly to such a system comprised of a system control unit (SCU) and one or more other devices, preferably battery-powered, implanted in the patient's body, i.e., within the envelope defined by the patient's skin. Each such implanted device is configured to be monitored and/or controlled by the SCU via a wireless communication channel. In accordance with the invention, the SCU comprises a programmable unit capable of (1) transmitting commands to at least some of a plurality of implanted devices and (2) receiving data signal from at least some of those implanted devices. In accordance with a preferred embodiment, the system operates in closed loop fashion whereby the commands transmitted by the SCU are dependent, in part, on the content of the data signals received by the SCU. In accordance with the invention, a preferred SCU is similarly implemented as a device capable of being implanted beneath a patient's skin, preferably having an axial dimension of less than 60 mm and a lateral dimension of less than 6 mm. Wireless communication between the SCU and the implanted devices is preferably implemented via a modulated sound signal, AC magnetic field, RF signal, or electric conduction.

    摘要翻译： 一种用于监测和/或影响患者身体的参数的系统，更具体地涉及由系统控制单元（SCU）和一个或多个其它装置（优选由电池供电的）组成的系统，其被植入患者体内，即，在 由病人皮肤定义的信封。 每个这样的植入装置被配置为经由无线通信信道由SCU监视和/或控制。 根据本发明，SCU包括能够（1）向多个植入装置中的至少一些发送命令的可编程单元，以及（2）从至少某些植入装置接收数据信号。 根据优选实施例，系统以闭环方式操作，由此由SCU发送的命令部分地取决于由SCU接收的数据信号的内容。 根据本发明，优选的SCU类似地实施为能够植入患者皮肤下方的装置，优选具有小于60mm的轴向尺寸和小于6mm的横向尺寸。 优选地，经由调制声音信号，AC磁场，RF信号或电传导来实现SCU与植入装置之间的无线通信。

    Low power rectifier circuit for implantable medical device
    9.
    发明授权
    Low power rectifier circuit for implantable medical device 失效
    用于植入式医疗设备的低功率整流电路

    公开(公告)号：US5999849A

    公开(公告)日：1999-12-07

    申请号：US928871

    申请日：1997-09-12

    申请人： John C. Gord ,  Lyle Dean Canfield

    发明人： John C. Gord ,  Lyle Dean Canfield

    IPC分类号： H02M7/12 ,  H02M7/21 ,  H02M7/219 ,  A61N1/08 ,  H02M7/217

    CPC分类号： H02M7/219 ,  A61N1/378

    摘要： A low power switched rectifier circuit is realized using P-MOS and N-MOS FET switches that are turned ON/OFF at just the right time by a detector and inverter circuit (which form an integral part of the rectifier circuit) to rectify an incoming ac signal in a highly efficient manner. Parasitic diodes and transistors that form an integral part of the FET circuitry respond to and rectify the incoming signal during start up, i.e., when no supply voltage is yet present, thereby providing sufficient operating voltage for the FET switches to begin to perform their intended rectifying function. In the absence of an incoming ac signal, i.e., during the time between biphasic pulses, the rectifier circuit is biased with an extremely small static bias current; but in the presence of an incoming ac signal, at a time when the positive and negative phases of the incoming signal are to be connected to positive and negative supply lines, a much larger dynamic bias current is automatically triggered.

    摘要翻译： 使用由适当的时间在检测器和逆变器电路（其形成整流电路的组成部分）的ON / OFF中的P-MOS和N-MOS FET开关来实现低功率开关整流电路，以纠正输入 交流信号以高效的方式。 形成FET电路的组成部分的寄生二极管和晶体管在启动期间响应并整流输入信号，即当没有电源电压时，从而为FET开关提供足够的工作电压，开始执行其预期的整流 功能。 在没有输入交流信号的情况下，即在双相脉冲之间的时间期间，整流电路以非常小的静态偏置电流偏置; 但是在存在进入的交流信号的情况下，在输入信号的正相和负相连接到正和负电源线的时候，自动触发大得多的动态偏置电流。

    Multichannel implantable cochlear stimulator
    10.
    发明授权
    Multichannel implantable cochlear stimulator 失效
    多声道植入式耳蜗刺激器

    公开(公告)号：US5776172A

    公开(公告)日：1998-07-07

    申请号：US450041

    申请日：1995-05-25

    申请人： Joseph H. Schulman ,  John C. Gord ,  Primoz Strojnik ,  David I. Whitmoyer ,  James H. Wolfe

    发明人： Joseph H. Schulman ,  John C. Gord ,  Primoz Strojnik ,  David I. Whitmoyer ,  James H. Wolfe

    IPC分类号： A61N1/36 ,  A61N1/372 ,  H04R25/00 ,  A61F2/18 ,  A61N1/32

    CPC分类号： A61N1/36032 ,  A61N1/36185 ,  A61N1/37252 ,  H04R25/505 ,  H04R2460/03

    摘要： An implantable cochlear stimulator (ICS) has eight output stages (212), each having a current source (212B) connected to a pair of electrodes, designated "A" and "B", through respective output coupling capacitors and an electrode switching matrix (212C). An indifferent electrode is connected to each output stage by way of an indifferent electrode switch (212D). The current source generates a precise stimulation current as a function of an analog control voltage. The analog control voltage, in turn, is generated by a logarithmic D/A converter. The D/A converter serially converts data words, received in a data frame from an external source, to respective analog control voltages that are applied sequentially to the current sources of each output stage. An output mode register (208) controls the switching matrix of each stage, as well as the indifferent electrode switch, to configure the electrodes for a desired stimulation configuration, e.g., bipolar stimulation (current flow between the pair of electrodes of the output stage), or monopolar stimulation (current flow between one of the electrodes of the output stage and the indifferent electrode). The voltage at the "A" and "B" electrode of each output stage may be selectively telemetered to the wearable system, as may the current flow through the indifferent electrode, thereby facilitating a measurement of the electrode impedance. The "A" and "B" electrodes of each output stage may be selectively shorted through a high or low resistance in order to discharge the output coupling capacitors.

    摘要翻译： 植入式耳蜗刺激器（ICS）具有八个输出级（212），每个输出级通过相应的输出耦合电容和电极开关矩阵（212）连接到一对电极（A“和”B“）上， 212C）。 无电极通过无关电极开关（212D）连接到每个输出级。 电流源产生精确的刺激电流作为模拟控制电压的函数。 模拟控制电压又由对数D / A转换器产生。 D / A转换器将数据帧中从外部源接收的数据字串行地转换为顺序施加到每个输出级的当前源的相应模拟控制电压。 输出模式寄存器（208）控制每个级的开关矩阵以及无关电极开关，以将电极配置为期望的刺激配置，例如双极刺激（输出级的一对电极之间的电流） ，或单极刺激（电流在输出级的电极和无关电极之间）。 每个输出级的“A”和“B”电极处的电压可以选择性地遥测到可穿戴系统，电流可以通过无关电极，从而便于电极阻抗的测量。 每个输出级的“A”和“B”电极可以通过高电阻或低电阻选择性短路，以便放电输出耦合电容器。