Physiologically active peptides
    1.
    发明申请
    Physiologically active peptides 失效
    生理活性肽

    公开(公告)号:US20050196861A1

    公开(公告)日:2005-09-08

    申请号:US11010800

    申请日:2004-12-13

    摘要: A peptide according to the present invention is selected from the group consisting of: (a) a peptide having the amino acid sequence represented by SEQ ID NO: 1; (b) a peptide having a modified amino acid sequence of the amino acid sequence described in (a) above, in which one or more amino acid residues are deleted, substituted, inserted or added, and having cell death-preventing activity and/or cell growth-promoting activity; and (c) a peptide which has an amino acid sequence having at least 80% homology with the peptide consisting of the amino acid sequence described in (a) above and has cell death-preventing activity and/or cell growth-promoting activity. The peptide has cell death-preventing activity and/or cell growth-promoting activity, is highly safe, and can be produced without difficulty. The peptide is useful as a culture supplement or as an effective component for a cell culture medium.

    摘要翻译: 根据本发明的肽选自:(a)具有由SEQ ID NO:1表示的氨基酸序列的肽; (b)具有上述(a)中所述的氨基酸序列的修饰氨基酸序列的肽,其中一个或多个氨基酸残基被缺失,取代,插入或添加并具有细胞死亡预防活性和/或 细胞生长促进活性; 和(c)具有与由上述(a)中所述的氨基酸序列组成的肽具有至少80%同源性的氨基酸序列并具有细胞死亡预防活性和/或细胞生长促进活性的肽。 肽具有细胞死亡预防活性和/或细胞生长促进活性,是高度安全的,可以毫无困难地制备。 该肽可用作培养物补充物或作为细胞培养基的有效成分。

    Protein and DNA encoding the same
    2.
    发明授权
    Protein and DNA encoding the same 失效
    蛋白质和DNA编码相同

    公开(公告)号:US07314745B2

    公开(公告)日:2008-01-01

    申请号:US10469486

    申请日:2002-03-01

    CPC分类号: C12N9/64 C12N9/6402

    摘要: An objective of the present invention is to provide a new protein derived from the silkworm middle silk gland and a DNA encoding said protein. The present invention relates to a protein of the following (a) or (b): (a) a protein comprising the amino acid sequence represented by SEQ ID NO: 1; (b) a protein comprising a modified amino acid sequence of the amino acid sequence described in (a) above, in which one or more amino acid residues are deleted, substituted, inserted or added, and having protease activity.

    摘要翻译: 本发明的目的是提供一种来自蚕丝绸的新蛋白质和编码所述蛋白质的DNA。 本发明涉及以下(a)或(b)的蛋白质:(a)包含SEQ ID NO:1所示的氨基酸序列的蛋白质; (b)包含上述(a)中描述的氨基酸序列的修饰氨基酸序列的蛋白质,其中一个或多个氨基酸残基被缺失,取代,插入或添加并具有蛋白酶活性。

    Physiologically active peptides
    3.
    发明授权
    Physiologically active peptides 失效
    生理活性肽

    公开(公告)号:US07329726B2

    公开(公告)日:2008-02-12

    申请号:US11010800

    申请日:2004-12-13

    IPC分类号: C07K7/06 A61K38/08 C12N5/02

    摘要: A peptide according to the present invention is selected from the group consisting of: (a) a peptide having the amino acid sequence represented by SEQ ID NO: 1; (b) a peptide having a modified amino acid sequence of the amino acid sequence described in (a) above, in which one or more amino acid residues are deleted, substituted, inserted or added, and having cell death-preventing activity and/or cell growth-promoting activity; and (c) a peptide which has an amino acid sequence having at least 80% homology with the peptide consisting of the amino acid sequence described in (a) above and has cell death-preventing activity and/or cell growth-promoting activity. The peptide has cell death-preventing activity and/or cell growth-promoting activity, is highly safe, and can be produced without difficulty. The peptide is useful as a culture supplement or as an effective component for a cell culture medium.

    摘要翻译: 根据本发明的肽选自:(a)具有由SEQ ID NO:1表示的氨基酸序列的肽; (b)具有上述(a)中所述的氨基酸序列的修饰氨基酸序列的肽,其中一个或多个氨基酸残基被缺失,取代,插入或添加并具有细胞死亡预防活性和/或 细胞生长促进活性; 和(c)具有与由上述(a)中所述的氨基酸序列组成的肽具有至少80%同源性的氨基酸序列并具有细胞死亡预防活性和/或细胞生长促进活性的肽。 肽具有细胞死亡预防活性和/或细胞生长促进活性,是高度安全的,可以毫无困难地制备。 该肽可用作培养物补充物或作为细胞培养基的有效成分。

    Method of preventing decrease in the activity of protein due to freezing and use of polypeptide in the production of protein activity decrease preventing agent
    4.
    发明授权
    Method of preventing decrease in the activity of protein due to freezing and use of polypeptide in the production of protein activity decrease preventing agent 失效
    防止蛋白质由于冷冻和使用多肽而在蛋白质活性产生中降低活性降低防止剂的方法

    公开(公告)号:US06887979B2

    公开(公告)日:2005-05-03

    申请号:US10148306

    申请日:2001-10-01

    CPC分类号: C12N9/96 C07K14/435

    摘要: An objective of the present invention is to provide a means to prevent freeze-induced decrease in protein activity. The present invention relates to a method for preventing freeze-induced decrease in protein activity comprising adding a polypeptide comprising the following amino acid sequence (I) to a protein to be frozen. Further, the present invention relates to use of a polypeptide comprising the following amino acid sequence (I) to produce an agent for preventing freeze-induced decrease in protein activity: (SEQ ID NO: 1) Ser-Ser-Thr-Gly-Ser-X1-Ser-X2-Thr-Asp-X3-X4-X5-X6- X7-X8-Gly-Ser-X9-Thr-Ser-Gly-Gly-Ser-Ser-Thr-Tyr- Gly-Tyr-Ser-Ser-X10-X11-X12-X13-Gly-X14-Val (I).

    摘要翻译: 本发明的目的是提供一种防止冻干引起的蛋白质活性降低的方法。 本发明涉及一种用于预防冷冻诱导的蛋白质活性降低的方法,其包括将包含以下氨基酸序列(I)的多肽加入待冷冻的蛋白质中。 此外,本发明涉及包含以下氨基酸序列(I)的多肽的用途来制备用于预防冻干诱导的蛋白质活性降低的试剂:

    SEQ ID NO:1) < colspec colname =“1”colwidth =“217pt”align =“left”/> Ser-Ser-Thr-Gly-Ser-X1-Ser-X2-Thr-Asp-X3-X4-X5-X6 - X7-X8 -Gly-Ser-X9-Thr-Ser-Gly-Gly-Ser-Ser-Thr-Tyr -Gy-Tyr-Ser-Ser-X10-X11-X12 -X13-Gly-X14-Val(I)。

      Ball transfer unit and ball table
      6.
      发明授权
      Ball transfer unit and ball table 失效
      球传输单元和球台

      公开(公告)号:US07370746B2

      公开(公告)日:2008-05-13

      申请号:US10561568

      申请日:2004-07-01

      IPC分类号: B35G13/00

      摘要: A ball transfer unit comprising a body in a seat face recessed in a semispherical shape is formed, a plurality of small balls rollingly in contact with the seat face of the body, a large ball rollingly in contact with the plurality of small balls, and a cover fitted to the body to hold the large ball and hold the small balls between the large ball and the seat face of the body. At least the body and the large ball are formed of either of PAI, PBI, PCTFE, PEEK, PEI, PI, PPs, melamine resin, aromatic polyamide resin, aluminum oxide, zirconium oxide, and silicon nitride.

      摘要翻译: 一种球形传送装置,其特征在于,具有以半球形凹陷的座面的主体,与所述主体的座面滚动地滚动的多个小球,与所述多个小球滚动地接触的大球, 盖子安装在身体上以握住大球,并将小球保持在大球和身体的座面之间。 至少身体和大球由PAI,PBI,PCTFE,PEEK,PEI,PI,PP,三聚氰胺树脂,芳族聚酰胺树脂,氧化铝,氧化锆和氮化硅中的任一种形成。

      Information processing system and method for timing adjustment
      7.
      发明授权
      Information processing system and method for timing adjustment 有权
      信息处理系统及时序调整方法

      公开(公告)号:US07337347B2

      公开(公告)日:2008-02-26

      申请号:US10998151

      申请日:2004-11-29

      CPC分类号: G06F1/14

      摘要: An elapsed cycle number during the predetermined period of the inputted clock source is counted using the clock reference signal as a yardstick, a frequency of the clock source is computed based on an elapsed cycle number obtained by counting, control timing of various interfaces relating to the CPU is adjusted and an interruption generating interval in which interruption is generated regularly by the CPU so that adjustment of control timing of various interfaces and setting of a timer interruption interval during the OS operation in accordance with a frequency of the clock source without performing OS modification such as rebuilding and the like.

      摘要翻译: 使用时钟参考信号作为衡量标准,在输入的时钟源的预定时段期间的经过周期数被计数,基于通过计数获得的经过的周期数来计算时钟源的频率,控制与 CPU被调整,并且中断生成间隔由CPU定期产生中断,从而根据时钟源的频率在OS操作期间调整各种接口的控制定时并设置定时器中断间隔,而不进行OS修改 例如重建等。

      Focus control apparatus for multilayer optical recording medium
      9.
      发明授权
      Focus control apparatus for multilayer optical recording medium 失效
      用于多层光记录介质的聚焦控制装置

      公开(公告)号:US06147942A

      公开(公告)日:2000-11-14

      申请号:US112004

      申请日:1998-07-08

      IPC分类号: G11B7/00 G11B7/085 G11B7/09

      摘要: A focus control apparatus for a multilayer optical recording medium which performs an appropriate focus jump on a multilayer optical recording medium. This focus control apparatus implements such focus jump control as to temporarily release a focus servo on one layer of a loaded multilayer optical recording medium, shift the focus position of read light on another target layer and then restart the focus servo on the another target layer, detects an ambient temperature, sets a drive signal condition according to the temperature detection output, and moves the focus position of the read light under the set drive signal condition. Specifically, this apparatus generates an acceleration signal to start moving the focus position of read light and a deceleration signal to decelerate movement of the focus position of the read light, as drive signals for a focus actuator in order to execute a focus jump operation, detects an ambient temperature of the focus actuator, and sets signal conditions for the acceleration signal and the deceleration signal according to the detected temperature.

      摘要翻译: 一种用于在多层光学记录介质上执行适当的聚焦跳跃的多层光学记录介质的聚焦控制装置。 该聚焦控制装置实现这样的聚焦跳跃控制,以暂时释放加载的多层光记录介质的一层上的聚焦伺服,将读取光的聚焦位置移动到另一目标层上,然后在另一目标层上重新启动聚焦伺服, 检测环境温度,根据温度检测输出设定驱动信号状态,并在设定的驱动信号条件下移动读取光的聚焦位置。 具体地,该装置产生加速度信号,开始移动读取光的聚焦位置和减速信号,以减慢读取光的焦点位置的移动,作为聚焦致动器的驱动信号,以执行聚焦跳跃操作,检测 聚焦致动器的环境温度,并且根据检测到的温度设置用于加速度信号和减速信号的信号条件。

      Process for producing liquid egg having reduced cholesterol content
      10.
      发明授权
      Process for producing liquid egg having reduced cholesterol content 失效
      生产含有减少胆固醇含量的液体蛋鸡的方法

      公开(公告)号:US5116628A

      公开(公告)日:1992-05-26

      申请号:US599840

      申请日:1990-10-19

      IPC分类号: A23L5/20 A23L15/00 A23L33/00

      摘要: A process for producing liquid egg having a reduced cholesterol content having flavor and taste comparable to conventional liquid egg having a normal cholesterol content is disclosed. The liquid egg having a reduced cholesterol content is produced by contacting liquid egg with a supercritical fluid to extract cholesterol from the liquid egg. Food whose raw material is the liquid egg having a reduced cholesterol content produced by the above process is also disclosed, as well as a new use for a wetted wall column system for producing the liquid egg noted above.

      摘要翻译: 公开了一种生产具有与具有正常胆固醇含量的常规液体鸡蛋相当的风味和味道的具有降低的胆固醇含量的液体蛋的方法。 具有降低的胆固醇含量的液体蛋通过使液体蛋与超临界流体接触以从液体鸡蛋中提取胆固醇而产生。 还公开了其原料是通过上述方法生产的具有降低的胆固醇含量的液体蛋的食物,以及用于生产上述液体蛋的湿壁塔系统的新用途。