公开(公告)号：US08519185B2

公开(公告)日：2013-08-27

申请号：US12084118

申请日：2006-10-26

申请人： Shinya Okazaki ,  Kaori Matoishi ,  Kiyoshi Itou

发明人： Shinya Okazaki ,  Kaori Matoishi ,  Kiyoshi Itou

IPC分类号： C07C51/42

CPC分类号： C07C59/06 ,  B01D61/44 ,  B01D61/445 ,  B01D2325/14 ,  B01D2325/16 ,  C07C51/47 ,  C08G63/06 ,  C12P7/42 ,  Y02A20/134

摘要： Glycolic acid having a high purity is obtained by subjecting glycolic acid or a glycolic acid solution containing contaminants to double-chamber electrodialysis combined with one or more treatments selected from among treatment with an activated carbon, treatment with an ion exchange resin, concentration treatment and cooling crystallization.

摘要翻译： 通过对含有污染物的乙醇酸或乙醇酸溶液进行双室电渗析，结合选自活性炭处理的一种或多种处理，用离子交换树脂处理，浓缩处理和冷却，获得具有高纯度的乙醇酸 结晶。

公开(公告)号：US20100022740A1

公开(公告)日：2010-01-28

申请号：US12084118

申请日：2006-10-26

申请人： Shinya Okazaki ,  Kaori Matoishi ,  Kiyoshi Itou

发明人： Shinya Okazaki ,  Kaori Matoishi ,  Kiyoshi Itou

IPC分类号： C07C59/06 ,  C08G67/00 ,  C09K3/00 ,  B01D61/42 ,  B01D61/44

CPC分类号： C07C59/06 ,  B01D61/44 ,  B01D61/445 ,  B01D2325/14 ,  B01D2325/16 ,  C07C51/47 ,  C08G63/06 ,  C12P7/42 ,  Y02A20/134

摘要： Glycolic acid having a high purity is obtained by subjecting glycolic acid or a glycolic acid solution containing contaminants to double-chamber electrodialysis combined with one or more treatments selected from among treatment with an activated carbon, treatment with an ion exchange resin, concentration treatment and cooling crystallization.

摘要翻译： 通过对含有污染物的乙醇酸或乙醇酸溶液进行双室电渗析，结合选自活性炭处理的一种或多种处理，用离子交换树脂处理，浓缩处理和冷却，获得具有高纯度的乙醇酸 结晶。

公开(公告)号：US20070009985A1

公开(公告)日：2007-01-11

申请号：US10539560

申请日：2003-12-15

申请人： Toshifumi Yamaki ,  Shinichi Banba ,  Kaori Matoishi ,  Kiyoshi Ito ,  Hideki Kobayashi ,  Eishi Tanaka ,  Toshihiro Oikawa

发明人： Toshifumi Yamaki ,  Shinichi Banba ,  Kaori Matoishi ,  Kiyoshi Ito ,  Hideki Kobayashi ,  Eishi Tanaka ,  Toshihiro Oikawa

IPC分类号： C12P21/06 ,  C12P13/00 ,  C07H21/04 ,  C12N9/78 ,  C12N1/21

CPC分类号： C12Y402/01084 ,  C12N9/88

摘要： The amino acid sequence of a mutant which is obtained by introducing a novel mutation into a Pseudonocardia thermophila JCM3095-derived nitrile hydratase consisting of two types of heterogeneous subunits, and the base sequence of the gene are provided. The nitrile hydratase is modified by specifying the region to be modified in the stereostructure/amino acid sequence of the nitrile hydratase, and applying alteration such as substitution, insertion, deletion or the like, to the amino acids in the amino acid sequence which are corresponding to the amino acid residues forming the region. Also provided is a method for modifying an enzyme having a nitrile hydratase activity.

摘要翻译： 提供了通过将新突变引入由两种异质亚基组成的嗜热假诺卡氏菌JCM3095衍生的腈水合酶获得的突变体的氨基酸序列和该基因的碱基序列。 通过在腈水合酶的立体结构/氨基酸序列中指定待修饰的区域，并将替代，插入，缺失等的改变应用于氨基酸序列中相应的氨基酸序列中的氨基酸来修饰腈水合酶 到形成该区域的氨基酸残基。 还提供了修饰具有腈水合酶活性的酶的方法。

公开(公告)号：US20130344273A1

公开(公告)日：2013-12-26

申请号：US13980950

申请日：2012-01-18

申请人： Kaori Matoishi ,  Takuma Yano ,  Hiromasa Marubayashi ,  Naoki Tomoshige ,  Naoshi Nagai ,  Tamotsu Harada ,  Kuniaki Kawabe

发明人： Kaori Matoishi ,  Takuma Yano ,  Hiromasa Marubayashi ,  Naoki Tomoshige ,  Naoshi Nagai ,  Tamotsu Harada ,  Kuniaki Kawabe

IPC分类号： C08L23/26

CPC分类号： C08L23/26 ,  C08F8/42 ,  C08F10/00 ,  C08F110/02 ,  C08F2810/40 ,  C08L23/10 ,  C08L83/00 ,  C08L83/04 ,  C08L101/10 ,  C08L2312/08 ,  Y10T428/1397 ,  Y10T428/249921 ,  C08L51/06

摘要： A molded article formed of a composition including 100 parts by weight of at least one kind of resin selected from the group consisting of thermoplastic resins and thermosetting resins, and 0.01 parts by weight to 10,000 parts by weight of a silylated polyolefin, which is obtained by a reaction between a silicon-containing compound containing a structural unit represented by Formula (1) and a vinyl group-containing compound having a defined number average molecular weight, a derivative thereof, or a mixture of these, —Si(R1)H—Y1—  (1) wherein R1 and Y1 are defined and with the proviso that the silylated polyolefin is not obtained by a reaction between a silicon-containing compound containing a structural unit represented by Formula (1) and having two or more SH groups per molecule and a compound having 2.0 or more vinyl groups on average per molecule as the vinyl group-containing compound.

摘要翻译： 由包含100重量份的选自热塑性树脂和热固性树脂的至少一种树脂和0.01重量份至10,000重量份的甲硅烷基化聚烯烃的组合物形成的模塑制品，其通过 包含式（1）表示的结构单元的含硅化合物和具有确定数均分子量的含乙烯基的化合物，其衍生物或它们的混合物之间的反应-Si（R1）H- Y 1 - （1）其中R1和Y1被定义，条件是甲硅烷基化聚烯烃不是通过含有由式（1）表示的结构单元的含硅化合物与每分子具有两个或更多个SH基团的反应而得到的 和每分子平均具有2.0个以上乙烯基的化合物作为含乙烯基的化合物。

公开(公告)号：US20100074083A1

公开(公告)日：2010-03-25

申请号：US12443374

申请日：2007-10-11

申请人： Atsushi Shibuya ,  Yukihiro Kumamoto ,  Masaru Wada ,  Shota Abe ,  Yuji Terado ,  Naruyoshi Mita ,  Kaori Matoishi

发明人： Atsushi Shibuya ,  Yukihiro Kumamoto ,  Masaru Wada ,  Shota Abe ,  Yuji Terado ,  Naruyoshi Mita ,  Kaori Matoishi

IPC分类号： G11B7/00 ,  C08K5/3492 ,  C07D403/14

CPC分类号： C08K5/34926 ,  C08L23/0823 ,  G11B7/1359 ,  G11B7/1372 ,  C08L23/08

摘要： Provided are a resin composition comprising 100 parts by mass of the polymer having an alicyclic structure at least in a part of a repeating structural unit and 0.05 to 5 parts by mass of a hindered amine compound having a carbon atom at a ratio of from 67% by weight to 80% by weight in the molecular structure and having a molecular weight of from 500 to 3500, a novel piperidine derivative having a piperidylaminotriazine skeleton, a molded product such as an optical component obtained by molding the resin composition, and an optical pickup device which employs the optical component.

摘要翻译： 提供一种树脂组合物，其包含100质量份具有至少部分重复结构单元的脂环结构的聚合物和0.05〜5质量份具有67％的碳原子的受阻胺化合物， 在分子结构中为80重量％，分子量为500〜3500，具有哌啶基氨基三嗪骨架的新型哌啶衍生物，通过模塑该树脂组合物而得到的光学部件的成型品，以及光学拾取器 使用该光学部件的装置。

公开(公告)号：US07595184B2

公开(公告)日：2009-09-29

申请号：US10539560

申请日：2003-12-15

申请人： Toshifumi Yamaki ,  Shinichi Banba ,  Kaori Matoishi ,  Kiyoshi Ito ,  Hideki Kobayashi ,  Eishi Tanaka ,  Toshihiro Oikawa

发明人： Toshifumi Yamaki ,  Shinichi Banba ,  Kaori Matoishi ,  Kiyoshi Ito ,  Hideki Kobayashi ,  Eishi Tanaka ,  Toshihiro Oikawa

IPC分类号： C12N9/88 ,  C12N5/10 ,  C12N1/21 ,  C07K14/00 ,  C12P21/00 ,  C12N15/00 ,  C12Q1/527 ,  C07H21/00

CPC分类号： C12Y402/01084 ,  C12N9/88

摘要： The amino acid sequence of a mutant which is obtained by introducing a novel mutation into a Pseudonocardia thermophila JCM3095-derived nitrile hydratase consisting of two types of heterogeneous subunits, and the base sequence of the gene are provided. The nitrile hydratase is modified by specifying the region to be modified in the stereostructure/amino acid sequence of the nitrile hydratase, and applying alteration such as substitution, insertion, deletion or the like, to the amino acids in the amino acid sequence which are corresponding to the amino acid residues forming the region. Also provided is a method for modifying an enzyme having a nitrile hydratase activity.

摘要翻译： 提供了通过将新突变引入由两种异质亚基组成的嗜热假诺卡氏菌JCM3095衍生的腈水合酶获得的突变体的氨基酸序列和该基因的碱基序列。 通过在腈水合酶的立体结构/氨基酸序列中指定待修饰的区域，并将替代，插入，缺失等的改变应用于氨基酸序列中相应的氨基酸序列中的氨基酸来修饰腈水合酶 到形成该区域的氨基酸残基。 还提供了修饰具有腈水合酶活性的酶的方法。

公开(公告)号：US20050233420A1

公开(公告)日：2005-10-20

申请号：US10967239

申请日：2004-10-19

申请人： Tadashi Araki ,  Ichirou Ikeda ,  Kaori Matoishi ,  Reiko Abe ,  Toshihiro Oikawa ,  Yasuko Matsuba ,  Hiroki Ishibashi ,  Kiyoteru Nagahara ,  Yasushi Fukuiri

发明人： Tadashi Araki ,  Ichirou Ikeda ,  Kaori Matoishi ,  Reiko Abe ,  Toshihiro Oikawa ,  Yasuko Matsuba ,  Hiroki Ishibashi ,  Kiyoteru Nagahara ,  Yasushi Fukuiri

IPC分类号： C12N1/21 ,  C12N9/10 ,  C12N15/54 ,  C12P19/38 ,  C12P19/30

CPC分类号： C12N9/1077 ,  C12P19/385

摘要： The invention provides a method for producing a cytosine nucleoside compound from pentose-1-phosphate and cytosine or a derivative thereof using a nucleoside phosphorylase reactive to cytosine or a bacterium having the enzyme activity. The invention also provides a method for specifically reducing an activity to degrade the substrates or the product, resulting in efficient production of the cytosine nucleoside compound. According to the invention, little by-product is produced in producing cytonucleocide compounds.

公开(公告)号：US09150422B2

公开(公告)日：2015-10-06

申请号：US13255719

申请日：2010-03-12

申请人： Norio Nakayama ,  Toshihiko Takaki ,  Haruhiko Fukumoto ,  Kaori Matoishi ,  Shiro Nakatsuka ,  Naoshi Nagai ,  Eiichi Takahashi ,  Yukiko Enomoto

发明人： Norio Nakayama ,  Toshihiko Takaki ,  Haruhiko Fukumoto ,  Kaori Matoishi ,  Shiro Nakatsuka ,  Naoshi Nagai ,  Eiichi Takahashi ,  Yukiko Enomoto

IPC分类号： C01G25/02 ,  C01B37/00 ,  H01M4/48 ,  H01M4/62 ,  H01M14/00 ,  H01G9/20

CPC分类号： C01B37/00 ,  H01G9/2031 ,  H01M4/48 ,  H01M4/62 ,  H01M14/005 ,  Y02E10/542 ,  Y02P70/521

摘要： Disclosed is a porous metal oxide obtained by subjecting metal alkoxide and/or a partially hydrolyzed condensate of the metal alkoxide to a sol-gel reaction in the presence of terminally branched copolymer particles represented by the following general formula (1) and having a number average molecular weight of not more than 2.5×104 to obtain an organic-inorganic composite and removing the terminally branched copolymer particles from the composite.

摘要翻译： 公开了一种多孔金属氧化物，其通过使金属醇盐和/或部分水解的金属醇盐的缩合物在由下列通式（1）表示的末端分支的共聚物颗粒存在下进行溶胶 - 凝胶反应而获得并具有数均分子量 分子量不超过2.5×10 4，得到有机 - 无机复合物，并从复合材料中除去末端支化的共聚物颗粒。

公开(公告)号：US20110118361A1

公开(公告)日：2011-05-19

申请号：US12811879

申请日：2009-01-06

申请人： Kaori Matoishi ,  Shiro Nakatsuka ,  Naoshi Nagai ,  Toshihiko Takaki ,  Haruhiko Fukumoto ,  Norio Nakayama

发明人： Kaori Matoishi ,  Shiro Nakatsuka ,  Naoshi Nagai ,  Toshihiko Takaki ,  Haruhiko Fukumoto ,  Norio Nakayama

IPC分类号： A61K47/34 ,  C08G65/48 ,  C08L71/08 ,  C08K3/22 ,  C09D11/00 ,  C08K5/42 ,  C08K5/43 ,  C08K5/41 ,  B32B23/04 ,  B32B9/00 ,  B32B5/16

CPC分类号： C09D123/36 ,  A61K8/0241 ,  A61K8/86 ,  A61K2800/654 ,  A61Q5/02 ,  A61Q19/10 ,  C08F8/00 ,  C08G65/2609 ,  C08G65/2624 ,  C08G65/2648 ,  C08K3/34 ,  C08K5/057 ,  C08L71/02 ,  C08L2205/05 ,  C09D1/00 ,  C09D5/02 ,  C09D7/65 ,  C09D7/67 ,  C09D11/106 ,  C09D123/06 ,  C09D123/10 ,  C09D171/02 ,  Y10T428/2982 ,  Y10T428/31855 ,  C08F10/00

摘要： Provided are polymer particles composed of a terminally branched copolymer represented by the following general formula (1) and having a number average molecular weight of not more than 2.5×104, wherein, in the formula, A represents a polyolefin chain; R1 and R2 each represent a hydrogen atom or an alkyl group having 1 to 18 carbon atoms, and at least one of R1 and R2 is a hydrogen atom; and X1 and X2 may be the same or different, and each a linear or branched polyalkylene glycol group.

摘要翻译： 提供由下列通式（1）表示的数均分子量不超过2.5×104的由末端支化共聚物组成的聚合物颗粒，其中，在该式中，A表示聚烯烃链; R 1和R 2各自表示氢原子或碳原子数1〜18的烷基，R 1和R 2中的至少一个为氢原子; X 1和X 2可以相同或不同，并且各自为直链或支链的聚亚烷基二醇基团。

公开(公告)号：US09534112B2

公开(公告)日：2017-01-03

申请号：US13980950

申请日：2012-01-18

申请人： Kaori Matoishi ,  Takuma Yano ,  Hiromasa Marubayashi ,  Naoki Tomoshige ,  Naoshi Nagai ,  Tamotsu Harada ,  Kuniaki Kawabe

发明人： Kaori Matoishi ,  Takuma Yano ,  Hiromasa Marubayashi ,  Naoki Tomoshige ,  Naoshi Nagai ,  Tamotsu Harada ,  Kuniaki Kawabe

IPC分类号： C08L23/26 ,  C08L83/08 ,  C08L101/10 ,  C08L83/00 ,  C08L83/04 ,  C08F110/02 ,  C08F10/00

CPC分类号： C08L23/26 ,  C08F8/42 ,  C08F10/00 ,  C08F110/02 ,  C08F2810/40 ,  C08L23/10 ,  C08L83/00 ,  C08L83/04 ,  C08L101/10 ,  C08L2312/08 ,  Y10T428/1397 ,  Y10T428/249921 ,  C08L51/06

摘要： A molded article formed of a composition including 100 parts by weight of at least one kind of resin selected from the group consisting of thermoplastic resins and thermosetting resins, and 0.01 parts by weight to 10,000 parts by weight of a silylated polyolefin, which is obtained by a reaction between a silicon-containing compound containing a structural unit represented by Formula (1) and a vinyl group-containing compound having a defined number average molecular weight, a derivative thereof, or a mixture of these, —Si(R1)H—Y1—  (1) wherein R1 and Y1 are defined and with the proviso that the silylated polyolefin is not obtained by a reaction between a silicon-containing compound containing a structural unit represented by Formula (1) and having two or more SH groups per molecule and a compound having 2.0 or more vinyl groups on average per molecule as the vinyl group-containing compound.

摘要翻译： 本发明的成形品是将由热塑性树脂和热固化性树脂组成的组中选出的至少一种树脂100重量份和0.01重量份〜10,000重量份的 通过含有式（1）表示的结构单元的含硅化合物与数均分子量等于或大于100且等于或等于或等于或等于100的含乙烯基的化合物之间的反应获得的甲硅烷基化聚烯烃， 通过GPC测量的小于500,000（这里，使用每分子具有2个以上SiH基的化合物作为含硅化合物的情况和每分子平均具有2.0个以上乙烯基的化合物作为含乙烯基的情况 化合物），其衍生物，或它们的混合物。 ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ-Si（R 1）HY 1 - €ƒ€ƒ€ƒ（1）（在公式（1）中，R 1表示氢 原子，卤原子或烃基，Y 1表示O，S或NR 30（R 30表示氢原子或烃基）。