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公开(公告)号:US20040194704A1
公开(公告)日:2004-10-07
申请号:US10409434
申请日:2003-04-07
Applicant: Surmodics, Inc.
Inventor: Ralph A. Chappa , Steven J. Porter
IPC: C23C016/00
CPC classification number: B05D1/002 , A61L31/10 , B05B13/0242 , B05B13/0442 , B05B16/40
Abstract: The invention provides an apparatus for coating a device comprising a coating chamber and a device rotator having at least one device mount wherein the apparatus allows insertion and retraction of the device on the device mount into and out of the coating chamber. In another aspect, the invention provides a method of applying a substantially uniform coating on a device comprising the steps of providing an apparatus for coating a device, mounting the device onto the device mount, purging the coating chamber to reduce humidity in the coating chamber, maintaining a reduced humidity content in the coating chamber, inserting the device into the coating chamber, disposing a coating material on the device and rotating the device mounts about the device axis.
Abstract translation: 本发明提供了一种用于涂覆装置的装置,该装置包括涂覆室和具有至少一个装置安装件的装置旋转器,其中装置允许装置在装置安装件上进出涂层室的插入和缩回。 另一方面,本发明提供了一种在装置上施加基本上均匀的涂层的方法,包括以下步骤:提供用于涂覆装置的装置,将装置安装到装置安装件上,清洗涂布室以减少涂覆室中的湿度, 保持涂布室中的湿度降低,将装置插入涂覆室中,将涂层材料设置在装置上并使装置围绕装置轴线旋转。
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公开(公告)号:US20040161547A1
公开(公告)日:2004-08-19
申请号:US10371043
申请日:2003-02-19
Applicant: SurModics, Inc.
Inventor: Mark F. Carlson , Steven J. Porter , Sean M. Stucke , Ralph A. Chappa
IPC: B05D003/06
CPC classification number: B05C3/109 , B05C9/14 , B05D1/18 , B05D3/061 , B05D2258/02
Abstract: This invention provides a coating apparatus and methods for coating a device, such as an industrially or medically applicable device. The apparatus is suitable for providing a coating using a photoactivatable compound and a polymerizable compound. In another aspect, the apparatus and methods are useful for coating a device wherein the surface of the device has small pores or apertures. The apparatus includes of containers suitable for holding the object to be coated and the coating solution, a gas supply source for supplying gas to solution, an irradiation station for providing light used in the coating process, and a conveyor mechanism to direct the containers to and from the irradiation station.
Abstract translation: 本发明提供一种涂覆装置和涂覆装置的方法,例如工业上或医学上适用的装置。 该装置适用于使用可光活化化合物和可聚合化合物提供涂层。 在另一方面,该装置和方法可用于涂覆装置,其中该装置的表面具有小的孔或孔。 该装置包括适于保持待涂覆物体和涂布溶液的容器,用于向溶液供应气体的气体供应源,用于提供在涂布过程中使用的光的照射台,以及输送机构, 从照射站。
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公开(公告)号:US20040137164A1
公开(公告)日:2004-07-15
申请号:US10745080
申请日:2003-12-23
Applicant: SURMODICS, INC.
Inventor: Dale G. Swan , Richard A. Amos , Terrence P. Everson , Stephen J. Chudzik , Ralph A. Chappa , Sean M. Stucke , Peter H. Duquette
IPC: C08G002/00
CPC classification number: C08J7/18 , A61L27/28 , A61L27/34 , A61L29/08 , A61L29/085 , A61L31/08 , A61L31/10 , A61L33/06 , A61L33/12 , B05D1/00 , B05D3/06 , B05D3/061 , B05D3/067 , B05D7/52 , G01N33/54353 , G01N33/54393 , Y10T428/31855
Abstract: A method of forming a polymer layer on a support surface by the use of a coating agent and polymerizable compounds. The coating agent provides photoreactive groups adapted to attach the agent to the surface, as well as photoreactive groups adapted to remain unattached to the surface, and thus serve as photoinitiators for the activation of polymerizable compounds in order to form a polymer layer thereon. Also provided are coating agents, per se, as well as a method of using such agents and the resultant surfaces and devices fabricated therefrom.
Abstract translation: 通过使用涂布剂和可聚合化合物在支撑体表面上形成聚合物层的方法。 涂覆剂提供适于将试剂连接到表面的光反应性基团,以及适于保持不附着于表面的光反应性基团,因此用作活化可聚合化合物的光引发剂,以在其上形成聚合物层。 本发明还提供涂层剂,以及使用这种试剂的方法以及由其制造的所得表面和装置。
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公开(公告)号:US20040062875A1
公开(公告)日:2004-04-01
申请号:US10256349
申请日:2002-09-27
Applicant: SurModics, Inc.
Inventor: Ralph A. Chappa , Mark F. Carlson
IPC: A61L002/00 , B05D001/02
CPC classification number: B05B7/0807 , B05B7/0861 , B05B7/0869 , B05B13/0207 , B05B13/0228 , B05B13/0436 , B05B13/0442 , B05D1/002 , B05D1/02
Abstract: A coating apparatus for coating a rollable device including a device rotator having a pair of rollers and spray nozzle is described. The spray nozzle produces a spray of coating material that is directed towards a gap that is between the rollers of the pair. The majority of any spray not deposited on the rollable device during a coating process passes through the gap between the rollers.
Abstract translation: 描述了一种用于涂覆可卷绕装置的涂覆装置,其包括具有一对辊和喷嘴的装置旋转体。 喷嘴产生喷涂的涂料,该喷涂材料指向一对间的间隙。 在涂布过程中,大部分没有沉积在可滚动装置上的喷雾通过辊之间的间隙。
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公开(公告)号:US20030190420A1
公开(公告)日:2003-10-09
申请号:US10429019
申请日:2003-05-01
Applicant: Surmodics, Inc
Inventor: Ralph A. Chappa , Steven J. Porter
IPC: B05D003/12
CPC classification number: B05B13/0442 , B05B7/0416 , B05B13/0242 , B05B13/0405 , B05B15/70
Abstract: The invention provides a device for holding a substrate during deposition processes that includes a rotation member rotatable about a first, central axis, and a plurality of substrate holders positioned on the rotation member, the substrate holders being rotatable about second axes. In another aspect, the invention provides a method of applying a substantially uniform coating on a substrate including the steps of providing a device of the invention; mounting a substrate onto the substrate mounts; providing at least one substrate coating station in spaced relation to the substrate mounts; rotating the rotation member about a central axis to position one or more of the substrate mounts at the substrate coating station; supplying the coating through the nozzle; moving the nozzle of the coating station in a direction parallel to the substrate at a predetermined rate to apply a uniform coating on the substrate; and rotating the substrate mounts about the second axes during the coating process.
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公开(公告)号:US20010026834A1
公开(公告)日:2001-10-04
申请号:US09847030
申请日:2001-05-01
Applicant: SurModics, Inc.
Inventor: Ralph A. Chappa , Steven J. Porter
IPC: A61L002/00 , B05D001/18 , B05D003/02
Abstract: A process and apparatus for dip-coating intermediate and/or discrete discontinuous portions of longitudinal devices, including medical devices such as catheters and guidewires. The apparatus provides a chamber in which both the desired portion(s) of the device and the coating solution can be controllably contacted. A controlled coating can be achieved within the chamber by providing and controlling one or more of the following relationships: a) the manner in which a chamber (containing solution) is itself moved with respect to a static device, b) the manner in which the device is moved with respect to a fixed chamber position containing a fixed volume of solution, and/or c) the manner in which both the chamber and device are fixed in position, and the coating is achieved by adding and removing a volume of solution from the chamber. The resultant movement of solution and device is intended to mimic or replicate the relative movements involved in a conventional dip-coating procedure, at least along the length of device to be coated.
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公开(公告)号:US20030148308A1
公开(公告)日:2003-08-07
申请号:US10192917
申请日:2002-07-09
Applicant: SurModics, Inc.
Inventor: Ralph A. Chappa , Sheau-Ping Hu , Dale G. Swan , Melvin J. Swanson , Patrick E. Guire
IPC: C12Q001/68 , C12M001/34 , B05D003/00
CPC classification number: B82Y30/00 , B01J2219/00317 , B01J2219/00531 , B01J2219/00605 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00621 , B01J2219/00626 , B01J2219/00635 , B01J2219/00637 , B01J2219/00659 , B01J2219/00677 , B01J2219/00711 , B01J2219/00716 , B01J2219/00722 , C07B2200/11 , C07C45/63 , C07C235/84 , C07C323/42 , C07H21/00 , C12Q1/6834 , C40B40/06 , C40B60/14 , C07C49/813
Abstract: Method and reagent composition for covalent attachment of target molecules, such as nucleic acids, onto the surface of a substrate. The reagent composition includes groups capable of covalently binding to the target molecule. Optionally, the composition can contain photoreactive groups for use in attaching the reagent composition to the surface. The reagent composition can be used to provide activated slides for use in preparing microarrays of nucleic acids.
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