利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

98 条记录 (耗时 0.043 秒)

    STIMULATION WAFEFORM GENERATOR FOR AN IMPLANTABLE MEDICAL DEVICE
    2.
    发明申请
    STIMULATION WAFEFORM GENERATOR FOR AN IMPLANTABLE MEDICAL DEVICE 有权
    用于可植入医疗器械的刺激波形发生器

    公开(公告)号：US20130289658A1

    公开(公告)日：2013-10-31

    申请号：US13458109

    申请日：2012-04-27

    申请人： Timothy J. Denison ,  Robert W. Hocken, JR. ,  Gabriela C. Molnar ,  Wesley A. Santa ,  Jalpa S. Shah ,  Larry E. Tyler

    发明人： Timothy J. Denison ,  Robert W. Hocken, JR. ,  Gabriela C. Molnar ,  Wesley A. Santa ,  Jalpa S. Shah ,  Larry E. Tyler

    IPC分类号： A61N1/36

    CPC分类号： A61N1/36125 ,  A61N1/378 ,  A61N1/3787

    摘要： This disclosure describes techniques for generating stimulation current pulses that have differing pulse shapes in a medical device. A circuit architecture is described that is configured to charge a capacitor to an initial amount of charge, modulate the amount of charge stored in the capacitor based on a control signal, and generate a stimulation current pulse that has an amplitude based on the amount charge stored in the capacitor. The circuit architecture may be configured to generate complex pulse shapes, such as, e.g., steps, ramps, bursts, and combinations thereof.

    摘要翻译： 本公开描述了用于在医疗装置中产生具有不同脉冲形状的刺激电流脉冲的技术。 描述了一种电路架构，其被配置为基于控制信号对电容器充电至初始电荷量，并且基于控制信号调制存储在电容器中的电荷量，并且产生具有基于存储的电荷量的幅度的刺激电流脉冲 在电容器中。 电路架构可以被配置为产生复数脉冲形状，例如步骤，斜坡，脉冲串及其组合。

    STIMULATION ELECTRODE SELECTION
    4.
    发明申请
    STIMULATION ELECTRODE SELECTION 有权
    刺激电极选择

    公开(公告)号：US20100100153A1

    公开(公告)日：2010-04-22

    申请号：US12563845

    申请日：2009-09-21

    申请人： David Carlson ,  Randy M. Jensen ,  Timothy J. Denison ,  Jianping Wu ,  Gabriela C. Molnar ,  Scott Stanslaski ,  William J. Marks

    发明人： David Carlson ,  Randy M. Jensen ,  Timothy J. Denison ,  Jianping Wu ,  Gabriela C. Molnar ,  Scott Stanslaski ,  William J. Marks

    IPC分类号： A61N1/36

    CPC分类号： A61N1/36067 ,  A61N1/0529 ,  A61N1/0534 ,  A61N1/36082 ,  A61N1/36185 ,  A61N1/37247

    摘要： Bioelectrical signals may be sensed within a brain of a patient with a plurality of sense electrode combinations. A stimulation electrode combination for delivering stimulation to the patient to manage a patient condition may be selected based on the frequency band characteristics of the sensed signals. In some examples, a stimulation electrode combination associated with the sense electrode combination that sensed a bioelectrical brain signal having a relatively highest relative beta band power level may be selected to deliver stimulation therapy to the patient. Other frequency bands characteristics may also be used to select the stimulation electrode combination.

    摘要翻译： 可以在具有多个感测电极组合的患者的脑内感测生物电信号。 可以基于感测信号的频带特性来选择用于将刺激递送给患者以管理患者状况的刺激电极组合。 在一些示例中，可以选择与检测到具有相对较高的相对β带功率水平的生物电脑信号的感测电极组合相关联的刺激电极组合，以向患者传递刺激治疗。 也可以使用其他频带特性来选择刺激电极组合。

    Determining intercardiac impedance
    9.
    发明授权
    Determining intercardiac impedance 有权
    确定心脏阻力

    公开(公告)号：US08478402B2

    公开(公告)日：2013-07-02

    申请号：US12263346

    申请日：2008-10-31

    申请人： John D. Wahlstrand ,  Timothy J. Denison ,  Wesley A. Santa

    发明人： John D. Wahlstrand ,  Timothy J. Denison ,  Wesley A. Santa

    IPC分类号： A61N1/00

    CPC分类号： A61B5/053 ,  A61B5/026 ,  A61B5/0538 ,  A61B5/6846 ,  A61B5/7217 ,  A61N1/36521

    摘要： A system and method for determining complex intercardiac impedance to detect various cardiac functions are disclosed involving a signal generator means for providing an adjustable direct current signal, a modulator for modulating the adjustable direct current signal to produce a modulated signal, at least one electrode for propagating the modulated signal across a myocardium, at least one sensor for detecting an outputted modulated signal from the myocardium, and at least one circuit to reduce the influence of process noise (aggressors) in the outputted modulated signal. The at least one circuit comprises an amplifier, a demodulator, and an integrator. The amplitude and phase of the final outputted modulated signal indicate the complex impedance of the myocardium. Changes in the complex impedance patterns of the myocardium provide indication of reduced oxygen and blood flow to the myocardium. The apparatus can be employed in implantable devices, including cardiac pacemakers and implantable cardioverter defibrillators.

    摘要翻译： 公开了一种用于确定复杂心脏阻抗以检测各种心脏功能的系统和方法，其涉及用于提供可调节直流电流信号的信号发生器装置，用于调制可调直流电信号以产生调制信号的调制器，用于传播的至少一个电极 跨越心肌的调制信号，用于检测来自心肌的输出的调制信号的至少一个传感器，以及至少一个电路，以减少输出的调制信号中的过程噪声（侵略者）的影响。 所述至少一个电路包括放大器，解调器和积分器。 最终输出的调制信号的振幅和相位表示心肌的复阻抗。 心肌复合阻抗模式的变化提供氧气和血液流向心肌的指示。 该装置可用于可植入装置，包括心脏起搏器和可植入的心律转复除颤器。

    OPTICAL STIMULATION THERAPY
    10.
    发明申请
    OPTICAL STIMULATION THERAPY 有权
    光刺激治疗

    公开(公告)号：US20110125077A1

    公开(公告)日：2011-05-26

    申请号：US12951766

    申请日：2010-11-22

    申请人： Timothy J. Denison ,  Kunal Paralikar ,  Gordon O. Munns ,  Wesley A. Santa ,  Peng Cong ,  Christian S. Nielsen ,  John D. Norton

    发明人： Timothy J. Denison ,  Kunal Paralikar ,  Gordon O. Munns ,  Wesley A. Santa ,  Peng Cong ,  Christian S. Nielsen ,  John D. Norton

    IPC分类号： A61N5/06 ,  A61N1/36 ,  A61M37/00

    CPC分类号： A61N5/0601 ,  A61B2017/00084 ,  A61B2018/00839 ,  A61M5/14276 ,  A61N1/086 ,  A61N1/365 ,  A61N5/062 ,  A61N5/0622 ,  A61N2005/0612 ,  A61N2005/0626 ,  A61N2005/063 ,  A61N2005/0651

    摘要： Methods of delivering optical stimulation to a target tissue from an optical stimulation device are provided. One method comprises sensing a temperature at the optical stimulation device or proximate to the optical stimulation device, and adjusting the delivery of light to the target tissue based on the sensed temperature. Another method comprises delivering the light to the target tissue with an optical light guide and sensing bioelectric signals with a sense electrode, wherein the optical light guide and the sense electrode each comprise a material that produces substantially no induced current in an electromagnetic field. Another method comprises delivering light from a light source of an optical stimulation device to a window of the optical stimulation device, delivering the light from the window to an optical light guide optically connected to the window, and delivering the light to a target tissue via the optical light guide.

    摘要翻译： 提供了从光学刺激装置向目标组织递送光学刺激的方法。 一种方法包括感测光学刺激装置处的温度或接近光学刺激装置的温度，以及基于感测的温度调节到目标组织的光的传送。 另一种方法包括用光学光导将光传送到目标组织，并用感测电极感测生物电信号，其中光学光导和感测电极各自包括在电磁场中基本上不产生感应电流的材料。 另一种方法包括将光从光学刺激装置的光源传送到光学刺激装置的窗口，将光从窗口传送到光学连接到窗户的光学导光板，并经由 光学光导。