摘要:
A device and a method for manipulating or analysing a liquid sample in a microfluidic channel are proposed. In order to implement an immunoassay, a movable substrate having a binding region is inserted in the channel. The substrate is embodied as a plate-like plastic part and is microstructured in the binding region. It is magnetically movable in the channel and for optical detection can be moved into a gas space.
摘要:
A microfluidic device and a method of producing it are proposed, in which a film covers a chamber in a carrier. The film is locally re-tightened in the region of the chamber after the film has been secured to the carrier. In this way it is possible to prevent undesirable bulging of the film into the chamber.
摘要:
The invention relates to a device for sample separation, particularly for blood separation, in which the sample liquid is introduced into a feed device. The sample flows vertically through a separating device such as a filter or a membrane, so that sample particles are retained and separated off.The sample liquid thus separated, particularly blood plasma, is received by an inlet chamber underneath the separating device and conveyed by means of a channel in the lateral direction out of the inlet chamber.Particularly advantageously, the channel extends into the inlet chamber, the channel being formed by a recess in the base of the inlet chamber.
摘要:
The present invention relates to devices for efficient transport, transfer and movement of fluids. In particular, the invention provides fluidic micro-structures for controlled transport and movement of liquids in devices for analytical and other purposes. Devices of the invention include one or more features that can enhance performance of the fluid transfer, referred to as a pre-shooter stop, a butterfly structure, a cascade structure, a waste chamber inlet, a capillary driven sample inlet chamber, a capillary stop structure, a bifurcation flow-through structure, and a hydrophobic vent.
摘要:
The invention relates to a device for sample separation, particularly for blood separation, in which the sample liquid is introduced into a feed device. The sample flows vertically through a separating device such as a filter or a membrane, so that sample particles are retained and separated off.The sample liquid thus separated, particularly blood plasma, is received by an inlet chamber underneath the separating device and conveyed by means of a channel in the lateral direction out of the inlet chamber.Particularly advantageously, the channel extends into the inlet chamber, the channel being formed by a recess in the base of the inlet chamber.
摘要:
A device is proposed having a separating device for filtering a liquid sample and having a conveying device. A positive pressure or negative pressure can be generated by means of the conveying device, for accelerating or assisting the filtration.
摘要:
A method for filling a cavity, of a packaging, particularly a blister packaging, with a liquid and a packaging suitable for this purpose are proposed. The cavity is completely filled with the liquid by an acceleration force or by continuous throughflow.
摘要:
A device is proposed having a separating device for filtering a liquid sample and having a conveying device. A positive pressure or negative pressure can be generated by means of the conveying device, for accelerating or assisting the filtration.
摘要:
The present invention relates to devices for efficient transport, transfer and movement of fluids. In particular, the invention provides fluidic micro-structures for controlled transport and movement of liquids in devices for analytical and other purposes. Devices of the invention include one or more features that can enhance performance of the fluid transfer, referred to as a pre-shooter stop, a butterfly structure, a cascade structure, a waste chamber inlet, a capillary driven sample inlet chamber, a capillary stop structure, a bifurcation flow-through structure, and a hydrophobic vent.
摘要:
The invention relates to a microfluidic arrangement for metering one or more first metered amounts of liquid (A) and for separating the latter from a second amount of liquid (B), having the following features: the arrangement has a first channel and one or more second channels; the first channel has one inlet and one outlet; in the area of the outlet the arrangement has a capillarity, which is greater than or equal to the capillarity in the area of the inlet; the one or more second channels branch off from the first channel at one or more branch points; the one or more second channels have a greater capillarity than the first channel at the branch points; and the one or more second channels have a predetermined volume. In the arrangement as depicted in the invention a liquid is transported in the first channel from the inlet to the outlet. At the branch points one portion of the liquid at a time enters the one or more second channels and fills them completely with the first metered amounts of liquid (A). The portion of the liquid remaining after the last branch point in the first channel emerges as the second amount of liquid via the outlet from the first channel. The amounts of liquid (A) metered in the one or more second channels are separated from the remaining amount of liquid (B) by a gas, which is located in the first channel after filling all one or more second channels.