Amphiphilic Peptides for Thoracic Air Leakage Occlusion
    6.
    发明申请
    Amphiphilic Peptides for Thoracic Air Leakage Occlusion 审中-公开
    两亲性肽用于胸腔漏气闭塞

    公开(公告)号:US20140329914A1

    公开(公告)日:2014-11-06

    申请号:US14239954

    申请日:2012-08-31

    IPC分类号: A61K47/42 A61K31/397

    摘要: Provided are compounds and methods useful for sealing air leaks in the thoracic cavity. Compounds and compositions of the invention comprise certain amphiphilic peptides, 8-200 amino acid residues long, that self-assemble spontaneously to form a gel in the presence of physiological pH and/or in the presence of a cation. In one embodiment, the peptide comprises a repeated sequence arginine-alanine-aspartic acid-alanine (RADA). Methods of the invention include a method of occluding a pulmonary air leak in a subject, comprising applying a compound of the invention to the site of a pulmonary air leak. The compounds and methods of the invention can be combined with other agents useful to treat cancer, inflammation, or infection.

    摘要翻译: 提供了用于密封胸腔漏气的化合物和方法。 本发明的化合物和组合物包含长达8-200个氨基酸残基的某些两亲肽,其在生理pH和/或阳离子存在下自发组装以形成凝胶。 在一个实施方案中,肽包含重复序列精氨酸 - 丙氨酸 - 天冬氨酸 - 丙氨酸(RADA)。 本发明的方法包括阻塞受试者的肺部空气泄漏的方法,包括将本发明的化合物施用于肺部空气泄漏的部位。 本发明的化合物和方法可以与可用于治疗癌症,炎症或感染的其它试剂组合。

    Data processing apparatus, data processing method and program
    9.
    发明授权
    Data processing apparatus, data processing method and program 有权
    数据处理装置,数据处理方法和程序

    公开(公告)号:US08489955B2

    公开(公告)日:2013-07-16

    申请号:US12743487

    申请日:2008-11-26

    IPC分类号: H03M13/00

    摘要: The present invention relates to a data processing apparatus, a data processing method and a program which can improve the tolerance of code bits of an LDPC code to errors.Where two or more bits of an LDPC (Low Density Parity Check) code are set as one symbol and are mapped to 214 or 216 signal points, a column twist interleaver 24 carries out, as a re-arrangement process for re-arranging code bits of an LDPC code such that a plurality of code bits corresponding to the value 1 included in one arbitrary row of a parity check matrix are not included in one symbol, column twist interleave of changing the writing starting position when code bits are written in a column direction of a memory for each column of the memory. The present invention can be applied, for example, to a transmission apparatus for transmitting an LDPC code.

    摘要翻译: 本发明涉及一种数据处理装置,数据处理方法和程序,其可以将LDPC码的码位的容限提高到错误。 当LDPC(低密度奇偶校验)码的两个或多个比特被设置为一个符号并被映射到214或216个信号点时,列扭曲交织器24执行用于重新排列码位的重新排列处理 使得与包括在奇偶校验矩阵的一个任意行中的值1相对应的多个码位不包括在一个符号中的LDPC码,当码位被写入列时改变写入起始位置的列扭曲交织 存储器的每列的存储器方向。 本发明可以应用于例如用于发送LDPC码的发送装置。

    Data processing apparatus and data processing method

    公开(公告)号:US08464122B2

    公开(公告)日:2013-06-11

    申请号:US12743398

    申请日:2008-11-26

    IPC分类号: H03M13/00

    摘要: The present invention relates to a data processing apparatus and a data processing method which can improve the tolerance to errors of data. A demultiplexer 25 replaces, in accordance with an allocation rule for allocating code bits of an LDPC code to symbol bits representative of symbols, mb bits from among the code bits and sets the code bits after the replacement as symbol bits of b symbols. For example, when m is 12 and b is 1, where the i+1th bits from the most significant bit of the 12×1 code bits and the 12×1 symbol bits of one symbol are represented as bits bi and yi, replacement for allocating, for example, b0 to y8, b1 to y0, b2 to y6, b3 to y1, b4 to y4, b5 to y5, b6 to y2, b7 to y3, b8 to y7, b9 to y10, b10 to y11 and b11 to y9 is carried out. The present invention can be applied, for example, to a transmission system for transmitting an LDPC code and so forth.