摘要:
A pyrimidinedione derivative compound has a basic backbone in which a phenyl group part and a pyrimidinedione part are linked by a structure comprising an alkyl chain containing at least two nitrogen atoms. The pyrimidinedione derivative is useful for a medical treatment of cardiac arrhythmias.
摘要:
Pyrimidinedione derivatives of the formula: ##STR1## wherein R.sup.1 and R.sup.2 is so linked with each other as to make an alkylene chain and thus form a heterocyclic structure, A, R.sup.3, R.sup.4, X.sup.1, X.sup.2 and X.sup.3 are substituents, respectively, and n is 2 or 3 have a basic backbone in which a phenyl group part and a pyrimidinedione part are linked by a structure comprising an alkyl chain and a heterocyclic ring having two nitrogen atoms. These compounds are useful for a medical treatment of cardiac arrhythmias.
摘要:
A pyrimidinedione derivative compound has a basic backbone in which a phenyl group part and a pyrimidinedione part are linked by a linking structure comprising an alkyl chain containing two nitrogen atoms. This linking structure is represented by ##STR1## [wherein A is --(CH.sub.2).sub.n --, --CO-- or --O--(CH.sub.2).sub.m --; each of R.sup.1 and R.sup.2 is independently a hydrogen atom or a lower alkyl group which may be substituted by a hydroxyl group, or R.sup.1 and R.sup.2 may be so linked with each other as to make an alkylene chain and thus form a heterocyclic structure; R.sup.5 is a halogen atom, a hydroxyl group, a lower alkyloxycarbonyl group, a lower alkyloxy group which may be substituted by a lower alkyloxy group, or a lower alkyl group which may be substituted by a hydroxyl group, or R.sup.5 may be so linked with R.sup.1 as to make an alkylene chain and thus form a heterocyclic structure; n is 0, 1, 2 or 3 (when R.sup.5 is the hydroxyl group, n.noteq.0); m is 0, 1, 2 or 3; and k is 0, 1, 2 or 3 (however, a compound in which A is --O--(CH.sub.2).sub.m -- and R.sup.5 is the hydroxyl group is excluded from the pyrimidinedione derivative)]. The pyrimidinedione derivative and its acid addition salt are useful for a medical treatment of cardiac arrhythmias.
摘要:
A pyrimidinedione derivative compound has a basic backbone in which a 4-oxobenzopyran ring group part and a pyrimidinedione part are linked by a structure comprising an alkyl chain containing at least two nitrogen atoms and one oxygen. The pyrimidinedione derivative is useful for a medical treatment of cardiac arrhythmias.
摘要:
Amine represented by the following formula (1), or their acid addition salts or their quaternary ammonium salts. ##STR1## The amines of formula (1) or their pharmaceutically acceptable acid addition salts or quaternary ammonium salts are useful for the treatment and prevention of heart diseases of animals, particularly arrhythima, myocardial infarction, angina pectoris and heart failure and psychoneurological diseases.
摘要:
In a hole examining device, an examination head (105) is supported to be movable in an X direction and a Y direction which are orthogonal to each other, measurement heads (125, 126) are supported to be movable in a Z direction which is orthogonal to the X direction and the Y direction with respect to the examination head (105), and a plurality of first measurers (127) and a plurality of second measurers (128) are arranged in the measurement heads (125, 126) in parallel and may be held at an advance position which advances as well as retreats with respect to the Z direction, thereby improving workability of an examining operation.
摘要:
There are provided processes for the preparation of .gamma.-methacryloxypropylsilane compounds which comprise carrying out the reaction of allyl methacrylate with a hydrosilane compound in the presence of a platinum catalyst, while allowing at least one of a hindered phenol compound and an aromatic amine compound to coexist in the reaction system with an alkylamine compound or an amide compound, or with a gas containing molecular oxygen, or with a phenol compound having an aminoalkylene group. By using these processes as provided, gelation of the reaction mixture in the reaction system and during the course of purification thereof by distillation can effectively be avoided, and the desired .gamma.-methacryloxypropylsilane compounds can be obtained in good yield.
摘要:
In a hole examining device, an examination head (105) is supported to be movable in an X direction and a Y direction which are orthogonal to each other, measurement heads (125, 126) are supported to be movable in a Z direction which is orthogonal to the X direction and the Y direction with respect to the examination head (105), and a plurality of first measurers (127) and a plurality of second measurers (128) are arranged in the measurement heads (125, 126) in parallel and may be held at an advance position which advances as well as retreats with respect to the Z direction, thereby improving workability of an examining operation.
摘要:
A processor includes a plurality of executing sections configured to simultaneously execute instructions for a plurality of threads, an instruction issuing section configured to issue instructions to the plurality of executing sections, and an instruction sync monitoring section configured to, when an instruction-synchronizing instruction is issued to one or more of the plurality of executing sections from the instruction issuing section, monitor completion of execution of the instruction-synchronizing instruction for each of the executing sections, to which the instruction-synchronizing instruction has been issued, thus detecting completion of execution of preceding instructions for the thread to which the instruction-synchronizing instruction belongs. After issuing the instruction-synchronizing instruction, the instruction issuing section stops issuance of succeeding instructions for the thread to which the instruction-synchronizing instruction belongs, until the completion of execution of the preceding instructions for the thread to which the instruction-synchronizing instruction belongs is detected by the instruction sync monitoring section.
摘要:
Disclosed herein is a floating-point number arithmetic circuit for efficiently supplying data to be performed arithmetic operation. The floating-point number arithmetic circuit includes an floating-point number arithmetic unit for performing a predetermined floating-point number arithmetic operation on a floating-point number of a predetermined precision, and a converting circuit for converting data into the floating-point number of predetermined precision and supplying the floating-point number of the predetermined precision to at least either one of input terminals of the floating-point number arithmetic unit.