Microelectromechanical heating apparatus and fluid preconcentrator device utilizing same
    1.
    发明授权
    Microelectromechanical heating apparatus and fluid preconcentrator device utilizing same 失效
    微机电加热装置和利用其的流体预浓缩装置

    公开(公告)号:US06914220B2

    公开(公告)日:2005-07-05

    申请号:US10396929

    申请日:2003-03-25

    摘要: A microelectromechanical heating apparatus and fluid preconcentrator device utilizing same wherein heating elements of the apparatus are sized and spaced to substantially uniformly heat a heating chamber within a heater of the apparatus. Tall, thermally-isolated heating elements are fabricated in Si using high aspect ratio etching technology. These tall heating elements have large surface area to provide large adsorbent capacity needed for high efficiency preconcentrators in a micro gas chromatography system (μGC). The tall heating elements are surrounded by air gaps to provide good thermal isolation, which is important for a low power preconcentrator in the μGC system.

    摘要翻译: 一种微机电加热装置和利用其的流体预浓缩器装置,其中装置的加热元件的尺寸和间隔尺寸以基本均匀地加热装置的加热器内的加热室。 使用高纵横比蚀刻技术在Si中制造高,热隔离的加热元件。 这些高加热元件具有较大的表面积,以提供微气相色谱系统(muGC)中高效预浓缩器所需的大的吸附剂能力。 高温加热元件被气隙包围以提供良好的热隔离,这对于muGC系统中的低功率预浓缩器是重要的。

    SMART NON-INVASIVE ARRAY-BASED HEMODYNAMIC MONITORING SYSTEM on CHIP AND METHOD THEREOF
    2.
    发明申请
    SMART NON-INVASIVE ARRAY-BASED HEMODYNAMIC MONITORING SYSTEM on CHIP AND METHOD THEREOF 审中-公开
    基于智能非基于阵列的HEMODYMM监测系统及其方法

    公开(公告)号:US20110208071A1

    公开(公告)日:2011-08-25

    申请号:US13034011

    申请日:2011-02-24

    IPC分类号: A61B5/02

    摘要: A non-invasive array-based hemodynamic monitoring system on chip is disclosed. The non-invasive array-based hemodynamic monitoring system on chip comprises a CMOS MEMS pressure sensor array, a readout circuit, and a signal control system. The CMOS MEMS pressure sensor array is configured to sense a pulse wave of a blood vessel. The readout circuit is coupled with each of the CMOS compatible MEMS pressure sensors and is configured to read the pulse wave and transformed the pulse wave into a voltage signal. The signal control system is coupled with each of the readout circuit, and is configured to estimate a wave velocity according to the voltage signal.

    摘要翻译: 公开了一种基于非侵入式阵列的血液动力学监测系统。 基于非侵入式阵列的血液动力学监测系统包括CMOS MEMS压力传感器阵列,读出电路和信号控制系统。 CMOS MEMS压力传感器阵列被配置为感测血管的脉搏波。 读出电路与每个CMOS兼容的MEMS压力传感器耦合,并且被配置为读取脉搏波并将脉冲波变换成电压信号。 信号控制系统与每个读出电路耦合,并且被配置为根据电压信号估计波速。

    Injection method for microfluidic chips
    3.
    发明授权
    Injection method for microfluidic chips 有权
    微流控芯片注射方法

    公开(公告)号:US07927476B2

    公开(公告)日:2011-04-19

    申请号:US12341233

    申请日:2008-12-22

    IPC分类号: G01N27/447 G01N27/453

    CPC分类号: B01D57/02

    摘要: Methods and systems for injecting a sample during electrophoresis, that generally comprise: loading a sieving matrix through a first end of a separation channel; having the an end of the sieving matrix at a set distance from the intersection of the separation channel and a loading channel; pressure loading a sample through the loading channel and filling an empty portion of the separation channel; applying an electric field across the separation channel while flowing a washing buffer through the loading channel; and injecting a portion of the sample into the separation channel, wherein the portion of the sample injected is of a size that is determined by a distance between the end of the sieving matrix and the intersection of the loading and separation channels.

    摘要翻译: 用于在电泳期间注射样品的方法和系统,其通常包括:通过分离通道的第一端装载筛分基质; 筛分矩阵的结束距离分离通道和加载通道的交点处一定距离; 通过加载通道加载样品并填充分离通道的空的部分; 在使洗涤缓冲液流过所述装载通道的同时,在所述分离通道上施加电场; 以及将所述样品的一部分注入所述分离通道中,其中所述注入的所述样品的所述部分具有由所述筛分矩阵的末端与所述加载和分离通道的交点之间的距离确定的尺寸。

    OPTOFLUIDIC DEVICES AND METHODS OF USING THE SAME
    4.
    发明申请
    OPTOFLUIDIC DEVICES AND METHODS OF USING THE SAME 失效
    光学器件及其使用方法

    公开(公告)号:US20090201497A1

    公开(公告)日:2009-08-13

    申请号:US11400947

    申请日:2006-04-10

    IPC分类号: G01J3/40 G01N21/01

    摘要: An optofluidic device is provided. The device includes a cladding region having a first refractive index, and a channel defined by the cladding region such that the cladding region forms an inner surface or an interface of the channel. The channel is configured to house one or more of a liquid, a solid, a gas, a colloidal, or a suspension sample, wherein the sample has a second refractive index, where the channel is configured to guide radiation, and where the first refractive index is lower than the second refractive index.

    摘要翻译: 提供了一种光流体装置。 该器件包括具有第一折射率的包层区域和由包层区域限定的沟道,使得包层区域形成沟道的内表面或界面。 通道被配置成容纳液体,固体,气体,胶体或悬浮样品中的一种或多种,​​其中样品具有第二折射率,其中通道被构造成引导辐射,并且其中第一折射 指数低于第二折射率。

    INJECTION METHOD FOR MICROFLUIDIC CHIPS
    5.
    发明申请
    INJECTION METHOD FOR MICROFLUIDIC CHIPS 失效
    微流感注射液的注射方法

    公开(公告)号:US20090166203A1

    公开(公告)日:2009-07-02

    申请号:US11965794

    申请日:2007-12-28

    IPC分类号: G01N27/26 G01N27/447

    CPC分类号: G01N27/44743

    摘要: A microchip for capillary electrophoresis is provided. The microchip comprises an injection channel and a separation channel configured to receive a sample through a sample well disposed on a first end of the separation channel; wherein the injection channel and the separation channel intersect to form a ‘T’ junction. The microchip further comprises a first valve disposed adjacent to the ‘T’ junction and on the separation channel and a second valve disposed at the ‘T’ junction. The second valve is a two-way valve. A sample plug is injected into an area between the ‘T’ junction and a second end of the separation channel.

    摘要翻译: 提供了用于毛细管电泳的微芯片。 微芯片包括注入通道和分离通道,其被配置为通过设置在分离通道的第一端上的样品阱接收样品; 其中注入通道和分离通道相交以形成“T”结。 所述微芯片还包括邻近所述“T”结和所述分离通道设置的第一阀,以及设置在所述“T”结处的第二阀。 第二个阀是一个二通阀。 将样品塞注入到“T”结和分离通道的第二端之间的区域中。

    INJECTION METHOD FOR MICROFLUIDIC CHIPS
    6.
    发明申请
    INJECTION METHOD FOR MICROFLUIDIC CHIPS 审中-公开
    微流感注射液的注射方法

    公开(公告)号:US20090166202A1

    公开(公告)日:2009-07-02

    申请号:US11965791

    申请日:2007-12-28

    IPC分类号: B01D57/02

    CPC分类号: G01N27/44743 G01N27/44791

    摘要: A microchip for electrophoresis is provided. The microchip comprises an injection channel and a separation channel configured to receive a sample through a sample well. The injection channel and the separation channel form a ‘T’ junction. The microchip comprises a first electrode disposed at a first end of the separation channel, a second electrode disposed in front of the ‘T’ junction and adjacent to the first electrode, a third electrode disposed at a first end of the injection channel and a fourth electrode disposed at a second end of the separation channel. A portion of the sample is injected and separated into an area between the ‘T’ junction and the fourth electrode.

    摘要翻译: 提供用于电泳的微芯片。 微芯片包括注入通道和配置成通过样品阱接收样品的分离通道。 注入通道和分离通道形成“T”结。 微芯片包括设置在分离通道的第一端的第一电极,设置在“T”结的前面并与第一电极相邻的第二电极,设置在注入通道的第一端的第三电极和第四电极 电极设置在分离通道的第二端。 样品的一部分被注入并分离成“T”结和第四电极之间的区域。

    MEMS based current sensor using magnetic-to-mechanical conversion and reference components
    7.
    发明授权
    MEMS based current sensor using magnetic-to-mechanical conversion and reference components 有权
    基于MEMS的电流传感器采用磁 - 机转换和参考元件

    公开(公告)号:US07466121B2

    公开(公告)日:2008-12-16

    申请号:US11506493

    申请日:2006-08-18

    IPC分类号: G01R33/00

    摘要: A micro-electromechanical system (MEMS) current sensor is described as including a first conductor, a magnetic field shaping component for shaping a magnetic field produced by a current in the first conductor, and a MEMS-based magnetic field sensing component including a magneto-MEMS component for sensing the shaped magnetic field and, in response thereto, providing an indication of the current in the first conductor. A method for sensing a current using MEMS is also described as including shaping a magnetic field produced with a current in a first conductor, sensing the shaped magnetic field with a MEMS-based magnetic field sensing component having a magneto-MEMS component magnetic field sensing circuit, and providing an indication of the current in the first conductor.

    摘要翻译: 微机电系统(MEMS)电流传感器被描述为包括第一导体,用于使由第一导体中的电流产生的磁场成形的磁场成形部件,以及包括磁 - 用于感测成形磁场的MEMS组件,并且响应于此,提供第一导体中的电流的指示。 还描述了一种用于感测使用MEMS的电流的方法,包括使用在第一导体中的电流产生的磁场成形,用具有磁MEMS组件磁场感测电路的基于MEMS的磁场感测组件感测成形的磁场 并且提供第一导体中的电流的指示。

    Isolation of short-circuited sensor cells for high-reliability operation of sensor array
    8.
    发明授权
    Isolation of short-circuited sensor cells for high-reliability operation of sensor array 有权
    隔离传感器阵列的高可靠性操作的短路传感器单元

    公开(公告)号:US07293462B2

    公开(公告)日:2007-11-13

    申请号:US11028789

    申请日:2005-01-04

    IPC分类号: G01H11/00

    CPC分类号: H04R23/00 B06B1/0292

    摘要: A device comprising an array of sensors and a multiplicity of bus lines, each sensor being electrically connected to a respective bus line and comprising a respective multiplicity of groups of micromachined sensor cells, the sensor cell groups of a particular sensor being electrically coupled to each other via the bus line to which that sensor is connected, each sensor cell group comprising a respective multiplicity of micromachined sensor cells that are electrically interconnected to each other and not switchably disconnectable from each other, the device further comprising means for isolating any one of the sensor cell groups from its associated bus line and in response to any one of the micromachined sensor cells of that sensor cell group being short-circuited to ground. In one implementation, the isolating means comprise a multiplicity of fuses. In another implementation, the isolating means comprise a multiplicity of short circuit protection modules, each module comprising a current sensor circuit and an electrical isolation switch.

    摘要翻译: 一种包括传感器阵列和多条总线线路的设备,每个传感器电连接到相应的总线,并且包括相应多个微机械传感器单元组,特定传感器的传感器单元组彼此电耦合 通过连接该传感器的总线,每个传感器单元组包括彼此电互连并且不可切换地彼此分离的相应多个微机械传感器单元,该装置还包括用于隔离传感器 来自其相关联的总线线路的单元组以及响应于该传感器单元组的微机械传感器单元中的任一个被短路到地。 在一个实施方案中,隔离装置包括多个保险丝。 在另一实施方案中,隔离装置包括多个短路保护模块,每个模块包括电流传感器电路和电隔离开关。

    LOW POWER PRECONCENTRATOR FOR MICRO GAS ANALYSIS
    9.
    发明申请
    LOW POWER PRECONCENTRATOR FOR MICRO GAS ANALYSIS 审中-公开
    用于微气体分析的低功率预处理器

    公开(公告)号:US20110094290A1

    公开(公告)日:2011-04-28

    申请号:US12605757

    申请日:2009-10-26

    IPC分类号: G01N1/40 G01N30/02 G01N1/44

    摘要: A low power preconcentrator for use in micro gas analysis, such as gas chromatography, and a system that employs the preconcentrator is disclosed. The preconcentrator includes a reservoir that comprises a heater membrane and elements coated at least partially with an adsorbent, and ports for receiving and discharging an analyte in communication with the reservoir. At least a portion of the reservoir (e.g., a cap) is made of a material having a thermal conductivity less than about 100 W/(m·K) and/or the heater membrane is made of a material that has a temperature difference less than about 75° C. when heated. The present invention has been described in terms of specific embodiment(s), and it is recognized that equivalents, alternatives, and modifications, aside from those expressly stated, are possible and within the scope of the appending claims.

    摘要翻译: 公开了一种用于微气体分析的低功率预浓缩器,例如气相色谱法,以及采用预浓缩器的系统。 预浓缩器包括储存器,其包括加热器膜和至少部分地涂覆有吸附剂的元件,以及用于接收和排出与储存器连通的分析物的端口。 储存器的至少一部分(例如,盖子)由热导率小于约100W /(m·K)的材料制成,和/或加热器膜由具有较低温度差的材料制成 加热时约为75℃。 已经根据具体实施例描述了本发明,并且认识到除了明确说明的那些之外的等同物,替代方案和修改是可能的并且在附加权利要求的范围内。