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公开(公告)号：US20150328021A1
公开(公告)日：2015-11-19
申请号：US14120397
申请日：2014-05-16
申请人： Michael S. Williams , Richard A. Glenn , Jeffrey A. Smith , Kevin D. Holbrook , Joseph M. DeSimone
发明人： Michael S. Williams , Richard A. Glenn , Jeffrey A. Smith , Kevin D. Holbrook , Joseph M. DeSimone
IPC分类号： A61F2/82
CPC分类号： A61F2/945 , A61F2/82 , A61F2/90 , A61F2210/0085 , A61F2220/0033 , A61F2250/0019 , A61F2250/0036 , A61F2250/0057
摘要： A woven tubular endoprosthesis comprising means for locking the endoprosthesis in a deployed configuration is disclosed. The means for locking the endoprosthesis may comprise locking protrusions, notches, a chemical bond, a curable bond, or other mechanism. The woven fibers comprising the endoprosthesis may be hollow and comprise circumferentially oriented polymeric chains, and may be filled with a curable material. A method of treatment using an endoprosthesis according to the invention is also disclosed.
摘要翻译： 公开了一种编织管状内假体，其包括用于将内置假体锁定在展开构造中的装置。 用于锁定内假体的装置可以包括锁定突起，凹口，化学键，可固化键或其它机构。 包含内用假体的编织纤维可以是中空的并且包括周向取向的聚合物链，并且可以用可固化材料填充。 还公开了使用根据本发明的内置假体的治疗方法。
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公开(公告)号：US06494917B1
公开(公告)日：2002-12-17
申请号：US09680229
申请日：2000-10-06
申请人： Harry A. McKellop , Fu-Wen Shen
发明人： Harry A. McKellop , Fu-Wen Shen
IPC分类号： A61F230
CPC分类号： C08J3/245 , A61F2/30767 , A61F2/3094 , A61F2/34 , A61F2002/30685 , A61F2002/30934 , A61F2002/30957 , A61F2250/0057 , A61L27/16 , A61L27/28 , A61L27/50 , B29B13/08 , B29C35/0266 , B29C71/04 , B29C2035/0877 , B29C2071/0027 , B29C2071/022 , B29C2791/001 , B29K2023/0675 , B29K2023/0683 , B29K2995/0087 , B29L2031/7532 , C08J2323/06 , C08L23/06 , Y10S623/901
摘要： A method for improving the wear resistance of an implant, made of polyethylene, by crosslinking its bearing surface layer, while leaving its non-bearing interior uncrosslinked. Such crosslinking may be achieved by electron-beam irradiation or by chemical crosslinking of the implant or the polyethylene from which the implant is made. The resulting implant or polyethylene may be further treated to remove the residual free radicals (generated by the electron beam crosslinking process); to remove residual chemicals (generated by the chemical crosslinking process); to remove its most oxidized layer; to stabilize its size and shape; to improve, by remelting, its oxidation resistance; and/or to reshape it into the final implant. Also presented are the resulting implant and polyethylene.
摘要翻译： 一种用于通过交联其承载表面层同时使其不承载内部未交联而改善由聚乙烯制成的植入物的耐磨性的方法。 这种交联可以通过电子束照射或植入物或聚合物的化学交联来实现，植入物由该聚合物制成。 可以进一步处理所得到的植入物或聚乙烯以除去残留的自由基（由电子束交联过程产生）; 去除残留的化学物质（由化学交联过程产生）; 去除其最氧化层; 稳定其尺寸和形状; 通过重熔改善其抗氧化性; 和/或将其重塑成最终植入物。 还提供了所得植入物和聚乙烯。
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公开(公告)号：US20070179607A1
公开(公告)日：2007-08-02
申请号：US11344265
申请日：2006-01-31
申请人： Robert Hodorek , Antony Lozier , Cheryl Blanchard
发明人： Robert Hodorek , Antony Lozier , Cheryl Blanchard
IPC分类号： A61F2/30
CPC分类号： A61F2/30756 , A61B17/842 , A61B17/86 , A61B17/8695 , A61F2/30749 , A61F2/30965 , A61F2/3859 , A61F2002/2817 , A61F2002/30004 , A61F2002/30008 , A61F2002/30011 , A61F2002/30075 , A61F2002/30093 , A61F2002/30306 , A61F2002/30462 , A61F2002/30467 , A61F2002/30502 , A61F2002/30616 , A61F2002/30751 , A61F2002/30841 , A61F2002/30957 , A61F2002/4631 , A61F2210/0019 , A61F2210/0061 , A61F2220/0008 , A61F2220/0025 , A61F2220/0075 , A61F2220/0083 , A61F2230/0097 , A61F2250/0014 , A61F2250/0017 , A61F2250/0018 , A61F2250/0023 , A61F2250/0057 , A61F2310/00011
摘要： A cartilage resurfacing implant is provided for replacing cartilage of an articulating portion of a bone at a skeletal joint having opposed joint surfaces. The cartilage resurfacing implant includes a body having a bearing surface and a bone interface. The bearing surface is able to support articulation with an opposing joint surface.
摘要翻译： 提供了一种软骨表面植入物，用于替代具有相对关节表面的骨骼关节处的骨的关节部分的软骨。 软骨表面置换植入物包括具有支承表面和骨界面的主体。 轴承表面能够支撑与相对接合表面的铰接。
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公开(公告)号：US20060149387A1
公开(公告)日：2006-07-06
申请号：US11027099
申请日：2004-12-30
申请人： Todd Smith , Mark Hanes , Richard King
发明人： Todd Smith , Mark Hanes , Richard King
CPC分类号： A61F2/4081 , A61F2/30767 , A61F2002/30158 , A61F2002/30685 , A61F2002/30884 , A61F2002/30902 , A61F2002/30957 , A61F2002/30971 , A61F2002/30973 , A61F2002/4631 , A61F2230/0026 , A61F2250/0057 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00179 , A61F2310/00353 , A61F2310/00952 , A61L27/34 , B29C43/18 , B29C43/203 , B29L2031/7532 , C08L23/06
摘要： An orthopaedic bearing includes a metallic component having a polymer composite secured thereto. A method of making an orthopaedic bearing is also disclosed.
摘要翻译： 矫形轴承包括固定有聚合物复合物的金属组分。 还公开了一种制造矫形轴承的方法。
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公开(公告)号：US5306311A
公开(公告)日：1994-04-26
申请号：US809003
申请日：1991-12-17
申请人： Kevin R. Stone , Shu-Tung Li
发明人： Kevin R. Stone , Shu-Tung Li
IPC分类号： A61L27/00 , A61F2/00 , A61F2/02 , A61F2/28 , A61F2/30 , A61F2/38 , A61F2/42 , A61F2/44 , A61L27/20 , A61L27/22 , A61L27/24 , A61L27/26 , A61L27/46 , A61L27/48 , A61L27/54 , A61L27/56 , A61L27/58 , A61F2/32
CPC分类号： A61L27/58 , A61F2/28 , A61F2/30756 , A61F2/3872 , A61F2/442 , A61L27/20 , A61L27/227 , A61L27/24 , A61L27/26 , A61L27/46 , A61L27/48 , A61L27/56 , A61F2/30907 , A61F2/3094 , A61F2/30965 , A61F2/38 , A61F2002/30006 , A61F2002/30062 , A61F2002/30113 , A61F2002/30131 , A61F2002/30205 , A61F2002/30225 , A61F2002/3023 , A61F2002/30677 , A61F2002/30736 , A61F2002/30766 , A61F2002/30808 , A61F2002/3082 , A61F2002/30822 , A61F2002/30827 , A61F2002/30879 , A61F2002/30881 , A61F2002/30891 , A61F2002/30904 , A61F2002/30957 , A61F2002/4276 , A61F2002/4279 , A61F2002/4282 , A61F2002/4284 , A61F2002/4289 , A61F2002/4292 , A61F2002/4294 , A61F2002/4297 , A61F2210/0004 , A61F2230/0006 , A61F2230/0013 , A61F2230/0067 , A61F2230/0069 , A61F2250/0015 , A61F2250/0057 , A61F2310/00365 , A61L2430/06 , A61L2430/38
摘要： A prosthetic, resorbable articular cartilage and methods of its fabrication and insertion are disclosed. The prosthetic articular cartilage, when implanted in a humanoid joint, acts as a resorbable scaffold for ingrowth of native articular chondrocytes and supports natural articulating joint forces. The prosthetic articular cartilage is a dry, porous, volume matrix of biocompatible and bioresorbable fibers. These fibers include a natural polymer or analogs thereof, at least a portion of which may be crosslinked. The matrix is adapted to have an in vivo outer surface contour substantially the same as that of natural articular cartilage in an articulating joint, and has a pore size in the approximate range of about 100 microns to about 400 microns.
摘要翻译： 公开了一种假体，可再吸收的关节软骨及其制造和插入的方法。 假体关节软骨植入人形关节时，作为天然关节软骨细胞向内生长的可吸收支架，并支持自然的关节联合力。 假体关节软骨是生物相容性和生物可再吸收纤维的干燥，多孔的体积基质。 这些纤维包括天然聚合物或其类似物，其至少一部分可以是交联的。 该基质适于具有与铰接接头中的天然关节软骨基本上相同的体内外表面轮廓，并且具有在约100微米至约400微米的近似范围内的孔径。
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公开(公告)号：US07955393B2
公开(公告)日：2011-06-07
申请号：US11868791
申请日：2007-10-08
申请人： Michael E. Hawkins
发明人： Michael E. Hawkins
IPC分类号： A61F2/38
CPC分类号： A61F2/389 , A61F2/2803 , A61F2/3094 , A61F2/30942 , A61F2/32 , A61F2/3804 , A61F2/40 , A61F2/4202 , A61F2/4241 , A61F2/4261 , A61F2/44 , A61F2002/30004 , A61F2002/30021 , A61F2002/30133 , A61F2002/30383 , A61F2002/30387 , A61F2002/30492 , A61F2002/30685 , A61F2002/30878 , A61F2002/30922 , A61F2002/30924 , A61F2002/30957 , A61F2220/0025 , A61F2230/0015 , A61F2250/0014 , A61F2250/0057 , A61F2310/00011 , A61F2310/00203 , A61F2310/00239
摘要： In one aspect of the invention, an implant includes first and second components to replace a portion of each of a pair of opposed articulating bone ends. The second component has means for low friction articulation with the first component and means for engaging the first component to constrain the motion between the components. The means for low friction articulation includes a first material exhibiting low wear and having a predetermined toughness value. The means for engaging includes a second material having a predetermined toughness value higher than the means for low friction articulation.
摘要翻译： 在本发明的一个方面，植入物包括用于替换一对相对的关节骨端部中的每一个的一部分的第一和第二部件。 第二部件具有用于与第一部件的低摩擦关节的装置和用于接合第一部件以限制部件之间的运动的装置。 用于低摩擦关节的装置包括具有低磨损并具有预定韧性值的第一材料。 用于接合的装置包括具有比用于低摩擦关节的装置高的预定韧性值的第二材料。
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公开(公告)号：US07896921B2
公开(公告)日：2011-03-01
申请号：US11027099
申请日：2004-12-30
申请人： Todd S. Smith , Mark D. Hanes , Richard King
发明人： Todd S. Smith , Mark D. Hanes , Richard King
CPC分类号： A61F2/4081 , A61F2/30767 , A61F2002/30158 , A61F2002/30685 , A61F2002/30884 , A61F2002/30902 , A61F2002/30957 , A61F2002/30971 , A61F2002/30973 , A61F2002/4631 , A61F2230/0026 , A61F2250/0057 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00179 , A61F2310/00353 , A61F2310/00952 , A61L27/34 , B29C43/18 , B29C43/203 , B29L2031/7532 , C08L23/06
摘要： An orthopaedic bearing includes a metallic component having a polymer composite secured thereto. A method of making an orthopaedic bearing is also disclosed.
摘要翻译： 矫形轴承包括固定有聚合物复合物的金属组分。 还公开了一种制造矫形轴承的方法。
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公开(公告)号：US07288115B2
公开(公告)日：2007-10-30
申请号：US10751087
申请日：2004-01-02
申请人： Michael E. Hawkins
发明人： Michael E. Hawkins
IPC分类号： A61F2/38
CPC分类号： A61F2/389 , A61F2/2803 , A61F2/3094 , A61F2/30942 , A61F2/32 , A61F2/3804 , A61F2/40 , A61F2/4202 , A61F2/4241 , A61F2/4261 , A61F2/44 , A61F2002/30004 , A61F2002/30021 , A61F2002/30133 , A61F2002/30383 , A61F2002/30387 , A61F2002/30492 , A61F2002/30685 , A61F2002/30878 , A61F2002/30922 , A61F2002/30924 , A61F2002/30957 , A61F2220/0025 , A61F2230/0015 , A61F2250/0014 , A61F2250/0057 , A61F2310/00011 , A61F2310/00203 , A61F2310/00239
摘要： The present invention provides an implant for replacing an articulating bone end adjacent a skeletal joint. The implant includes individual subcomponents having different physical and/or mechanical properties joined together into a multipart implant component.
摘要翻译： 本发明提供一种植入物，用于替代靠近骨骼关节的关节骨端。 植入物包括将具有不同物理和/或机械性质的各个子部件连接在一起成为多部分植入部件。
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公开(公告)号：US5624463A
公开(公告)日：1997-04-29
申请号：US232743
申请日：1994-04-25
申请人： Kevin R. Stone , Shu-Tung Li
发明人： Kevin R. Stone , Shu-Tung Li
IPC分类号： A61L27/00 , A61F2/00 , A61F2/02 , A61F2/28 , A61F2/30 , A61F2/38 , A61F2/42 , A61F2/44 , A61L27/20 , A61L27/22 , A61L27/24 , A61L27/26 , A61L27/46 , A61L27/48 , A61L27/54 , A61L27/56 , A61L27/58 , A61F2/50
CPC分类号： A61L27/58 , A61F2/28 , A61F2/30756 , A61F2/3872 , A61F2/442 , A61L27/20 , A61L27/227 , A61L27/24 , A61L27/26 , A61L27/46 , A61L27/48 , A61L27/56 , A61F2/30907 , A61F2/3094 , A61F2/30965 , A61F2/38 , A61F2002/30006 , A61F2002/30062 , A61F2002/30113 , A61F2002/30131 , A61F2002/30205 , A61F2002/30225 , A61F2002/3023 , A61F2002/30677 , A61F2002/30736 , A61F2002/30766 , A61F2002/30808 , A61F2002/3082 , A61F2002/30822 , A61F2002/30827 , A61F2002/30879 , A61F2002/30881 , A61F2002/30891 , A61F2002/30904 , A61F2002/30957 , A61F2002/4276 , A61F2002/4279 , A61F2002/4282 , A61F2002/4284 , A61F2002/4289 , A61F2002/4292 , A61F2002/4294 , A61F2002/4297 , A61F2210/0004 , A61F2230/0006 , A61F2230/0013 , A61F2230/0067 , A61F2230/0069 , A61F2250/0015 , A61F2250/0057 , A61F2310/00365 , A61L2430/06 , A61L2430/38
摘要： A prosthetic, resorbable articular cartilage and methods of its fabrication and insertion are disclosed. The prosthetic articular cartilage, when implanted in a humanoid joint, acts as a resorbable scaffold for ingrowth of native articular chondrocytes and supports natural articulating joint forces. The prosthetic articular cartilage is a dry, porous, volume matrix of biocompatible and bioresorbable fibers. These fibers include a natural polymer or analogs thereof, at least a portion of which may be crosslinked. The matrix is adapted to have an in vivo outer surface contour substantially the same as that of natural articular cartilage in an articulating joint, and has a pore size in the approximate range of about 100 microns to about 400 microns.
摘要翻译： 公开了一种假体，可再吸收的关节软骨及其制造和插入的方法。 假体关节软骨植入人形关节时，作为天然关节软骨细胞向内生长的可吸收支架，并支持自然的关节联合力。 假体关节软骨是生物相容性和生物可再吸收纤维的干燥，多孔的体积基质。 这些纤维包括天然聚合物或其类似物，其至少一部分可以是交联的。 该基质适于具有与铰接接头中的天然关节软骨基本上相同的体内外表面轮廓，并且具有在约100微米至约400微米的近似范围内的孔径。
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公开(公告)号：US20160074559A1
公开(公告)日：2016-03-17
申请号：US14784697
申请日：2014-04-17
发明人： Joel ROSENBLATT , Issam RAAD , Andrew P. DENNIS
CPC分类号： A61L27/54 , A61F2/12 , A61F2250/0018 , A61F2250/0057 , A61F2250/006 , A61F2250/0067 , A61L27/222 , A61L27/502 , A61L27/52 , A61L2300/404 , A61L2430/04 , A61M27/00
摘要： Biodegradable antimicrobial films are provided that are solid at room temperature and substantially liquefy in situ after implantation into a mammal, such as a human patient. Methods of using the films to cover a medical device, such as a breast implant, prior to insertion into a subject are also provided.
摘要翻译： 提供可生物降解的抗微生物膜，其在室温下为固体，并且在植入哺乳动物（例如人类患者）后基本上液化。 还提供了在插入受试者之前使用膜覆盖医疗装置（例如乳房植入物）的方法。
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