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公开(公告)号：US4450237A
公开(公告)日：1984-05-22
申请号：US529802
申请日：1983-09-06
CPC分类号： C07H17/08 , C12P19/62 , C12R1/47 , Y10S435/887
摘要： An antibiotic complex, consisting of two major components, has been isolated from fermentations of a new subspecies of Streptomyces albus culture. The two major components from the complex are two new macrolide antibiotics, which are active as antibacterial agents against certain gram-positive and gram-negative microorganisms.
摘要翻译： 由两种主要成分组成的抗生素复合物已经从新亚种链霉菌培养物的发酵中分离出来。 该复合物的两个主要成分是两种新的大环内酯类抗生素，它们作为针对某些革兰氏阳性和革兰氏阴性微生物的抗菌剂是有活性的。
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2.发明授权公开(公告)号：US07842494B2
公开(公告)日：2010-11-30
申请号：US10486747
申请日：2002-08-12
申请人： Gyorgy Botond Kiss , Istvan Ott
发明人： Gyorgy Botond Kiss , Istvan Ott
CPC分类号： C12R1/11 , A01N63/00 , C05F11/08 , C12N1/20 , C12R1/01 , C12R1/12 , C12R1/265 , C12R1/39 , C12R1/47
摘要： The present invention relates to product(s) containing living microorganism(s) suitable for soil treatment, microorganisms multiplying under different climatic and natural circumstances, as well as procedures for the production of the products, and procedures for the treatment of the soil and plants with the products. More particularly, the invention relates to a procedure for preparing the products from any of the microorganisms specified below, or from the mixture thereof. Furthermore, the invention relates to a procedure for the creation of the cultures of the microorganisms to be used. The subject invention also pertains to the microorganisms themselves. More particularly, the invention relates to a procedure for the treatment of the soil and the plants with a product containing at least one of the microorganisms selected from Azospirillum brasilense ssp. SW51 (NCAIM /P/ B 001293), Azotobacter vinelandii ssp. M657 (NCAIM /P/B 001292), Pseudomonas fluorescens var. SW11 (NCAIM /P/ B 001296), Bacillus polymyxa var. SW17 (NCAIM /P/ B 001295), Bacillus megaterium var. M326 (NCAIM /P/ B 001291), Micrococcus roseus ssp. A21 (NCAIM /P/B 001294), Bradyrhizobium japonicum var. PH25 (NCAIM /P/ B 001302), and Streptomyces albus var. 0003 LP (NCAIM /P/ B 001301), and furthermore the products multiplying and existing in the environment of the plant in question, containing the listed microorganisms and their production.
摘要翻译： 本发明涉及含有适于土壤处理的活微生物，不同气候和天然环境下的微生物繁殖的产品，以及产品的生产程序，以及土壤和植物的处理程序 与产品。 更具体地说，本发明涉及从以下指定的任何微生物或其混合物制备产物的方法。 此外，本发明涉及用于产生待使用的微生物培养物的方法。 本发明也涉及微生物本身。 更具体地说，本发明涉及一种用含有至少一种微生物处理土壤和植物的方法，所述微生物选自巴西喷虫（Azospirillum brasilense ssp） SW51（NCAIM / P / B 001293），Azotobacter vinelandii ssp。 M657（NCAIM / P / B 001292），荧光假单胞菌变种 SW11（NCAIM / P / B 001296），多粘芽孢杆菌变种 SW17（NCAIM / P / B 001295），巨大芽孢杆菌变种 M326（NCAIM / P / B 001291），Micrococcus roseus ssp。 A21（NCAIM / P / B 001294），日本的Bradyrhizobium japonicum var。 PH25（NCAIM / P / B 001302）和链霉菌（Streptomyces albus var。 0003 LP（NCAIM / P / B 001301），此外，产品在相关工厂的环境中繁殖和存在，包含列出的微生物及其生产。
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3.发明授权Enkastins: new glycopeptides which act to inhibit enkephlinase, processes for their preparation, and their use as pharmaceutical products 失效恩卡斯汀：用于抑制肠胃蛋白酶的新糖肽，其制备方法及其作为药物的用途
公开(公告)号：US5302582A
公开(公告)日：1994-04-12
申请号：US727388
申请日：1991-07-05
申请人： Laszlo Vertesy , Peter Schindler , Herbert Kogler , Hans-Wolfram Fehlhaber , Francoise Delevallee
发明人： Laszlo Vertesy , Peter Schindler , Herbert Kogler , Hans-Wolfram Fehlhaber , Francoise Delevallee
IPC分类号： C12P21/02 , A61K31/70 , A61K31/7028 , A61K38/00 , A61K38/55 , A61P25/04 , C07H7/02 , C07H15/12 , C07K1/113 , C07K5/06 , C07K9/00 , C07K14/195 , C07K14/41 , C07K14/81 , C07K17/00 , C12N1/14 , C12N1/20 , C12N9/99 , C12P19/26 , C12P19/28 , C12R1/47
摘要： The invention relates to new biologically active glycopeptides of the general formulaSacch--A--B--Rin which Sacch represents a monosaccharide residue with, where appropriate, the OH groups being partially or completely substituted,A represents the residue of a neutral L- or D-amino acid or --if B is absent--represents the residue of a neutral D-amino acid,B is absent or represents the residue of a neutral L- or D-amino acid or of an optionally .omega.-substituted bi-functional acidic or basic L- or D-amino acid, and R represents hydroxyl, (C.sub.1 -C.sub.8)-alkoxy, an amino radical which is optionally substituted by one or two identical or different radicals from the series comprising (C.sub.1 -C.sub.8)-alkyl, (C.sub.5 -C.sub.8)-cycloalkyl, (C.sub.5 -C.sub.8)-heteroalkyl or (C.sub.5 -C.sub.8)-heteroaryl, or another acid derivative. These compounds have enkephalinase-inhibiting properties and can thus be used, for example, as analgesics in human and veterinary medicine. The isolation of these compounds from Streptomyces albus ATCC 21838, and further processes for their preparation, are also described.
摘要翻译： 本发明涉及通式为Sacch-ABR的新的生物活性糖肽，其中Sacch代表单糖残基，在适当的情况下OH基部分或完全被取代，A代表中性L-或D-氨基酸的残基 或 - 如果B不存在 - 表示中性D-氨基酸的残基，B不存在或表示中性L-或D-氨基酸或任选（ω） - 取代的双官能酸性或碱性的残基 L-或D-氨基酸，R代表羟基，（C1-C8） - 烷氧基，任选被一个或两个相同或不同的基团取代的氨基，所述基团包括（C 1 -C 8） - 烷基， -C 8） - 环烷基，（C 5 -C 8） - 杂烷基或（C 5 -C 8） - 杂芳基或其它酸衍生物。 这些化合物具有脑啡肽酶抑制性质，因此可用于例如人和兽医学中的镇痛药。 这些化合物从Streptomyces albus ATCC 21838的分离以及其制备方法也被描述。
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公开(公告)号：US4411892A
公开(公告)日：1983-10-25
申请号：US374223
申请日：1982-05-03
IPC分类号： A61K31/70 , A61K31/7042 , A61K31/7048 , A61P31/04 , C07H17/08 , C12P19/62 , C12R1/465 , A61K31/71
摘要： An antibiotic complex, consisting of two major components, has been isolated from fermentations of a new subspecies of Streptomyces albus culture. The two major components from the complex are two new macrolide antibiotics, which are active as antibacterial agents against certain gram-positive and gram-negative microorganisms.
摘要翻译： 由两种主要成分组成的抗生素复合物已经从新亚种链霉菌培养物的发酵中分离出来。 该复合物的两个主要成分是两种新的大环内酯类抗生素，它们作为针对某些革兰氏阳性和革兰氏阴性微生物的抗菌剂是有活性的。
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公开(公告)号：US2998352A
公开(公告)日：1961-08-29
申请号：US80573359
申请日：1959-04-13
申请人： AMERICAN CYANAMID CO
CPC分类号： C12R1/465 , C12P29/00 , C12R1/47 , C12R1/485 , C12R1/55 , C12R1/585 , C12R1/59 , Y10S435/889 , Y10S435/898 , Y10S435/903 , Y10S435/904
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6.发明申请公开(公告)号：US20050060930A1
公开(公告)日：2005-03-24
申请号：US10486747
申请日：2002-08-12
申请人： Gyorgy Kiss , Istvan Ott
发明人： Gyorgy Kiss , Istvan Ott
CPC分类号： C12R1/11 , A01N63/00 , C05F11/08 , C12N1/20 , C12R1/01 , C12R1/12 , C12R1/265 , C12R1/39 , C12R1/47
摘要： The present invention relates to product(s) containing living microorganism(s) suitable for soil treatment, microorganisms multiplying under different climatic and natural circumstances, as well as procedures for the production of the products, and procedures for the treatment of the soil and plants with the products. More particularly, the invention relates to a procedure for preparing the products from any of the microorganisms specified below, or from the mixture thereof. Furthermore, the invention relates to a procedure for the creation of the cultures of the microorganisms to be used. The subject invention also pertains to the microorganisms themselves. More particularly, the invention relates to a procedure for the treatment of the soil and the plants with a product containing at least one of the microorganisms selected from Azospirillum brasilense ssp. SW51 (NCAIM /P/ B 001293), Azotobacter vinelandii ssp. M657 (NCAIM /P/B 001292), Pseudomonas fluorescens var. SW11 (NCAIM /P/ B 001296), Bacillus polymyxa var. SW17 (NCAIM /P/ B 001295), Bacillus megaterium var. M326 (NCAIM /P/ B 001291), Micrococcus roseus ssp. A21 (NCAIM /P/B 001294), Bradyrhizobium japonicum var. PH25 (NCAIM /P/ B 001302), and Streptomyces albus var. 0003 LP (NCAIM /P/ B 001301), and furthermore the products multiplying and existing in the environment of the plant in question, containing the listed microorganisms and their production.
摘要翻译： 本发明涉及含有适于土壤处理的活微生物，不同气候和天然环境下的微生物繁殖的产品，以及产品的生产程序，以及土壤和植物的处理程序 与产品。 更具体地说，本发明涉及从以下指定的任何微生物或其混合物制备产物的方法。 此外，本发明涉及用于产生待使用的微生物培养物的方法。 本发明也涉及微生物本身。 更具体地说，本发明涉及一种用含有至少一种微生物处理土壤和植物的方法，所述微生物选自巴西喷虫（Azospirillum brasilense ssp） SW51（NCAIM / P / B 001293），Azotobacter vinelandii ssp。 M657（NCAIM / P / B 001292），荧光假单胞菌变种 SW11（NCAIM / P / B 001296），多粘芽孢杆菌变种 SW17（NCAIM / P / B 001295），巨大芽孢杆菌变种 M326（NCAIM / P / B 001291），Micrococcus roseus ssp。 A21（NCAIM / P / B 001294），日本的Bradyrhizobium japonicum var。 PH25（NCAIM / P / B 001302）和链霉菌（Streptomyces albus var。 0003 LP（NCAIM / P / B 001301），此外，产品在相关工厂的环境中繁殖和存在，包含列出的微生物及其生产。
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公开(公告)号：US4935362A
公开(公告)日：1990-06-19
申请号：US31955
申请日：1987-03-30
IPC分类号： C07D487/04 , C12P17/18
CPC分类号： C07D487/04 , C12P17/182 , C12R1/47 , Y10S435/887
摘要： A new antitumor antibiotic designated herein as BMY-28121 is produced by fermentation of Streptomyces albus strain K7331-113 (ATCC 39897). BMY-28121, which may be recovered from the fermentation broth in either its natural free hydroxy form (BMY-28121A) or methyl ether form (BMY-28121B), inhibits gram-positive bacteria and anaerobes and inhibits the growth of mammalian tumors such as P-388 leukemia, L-1210 leukemia and B16 melanoma.
摘要翻译： 本文命名为BMY-28121的新抗肿瘤抗生素是通过发酵链霉菌株K7331-113（ATCC 39897）产生的。 可以从其天然游离羟基形式（BMY-28121A）或甲基醚形式（BMY-28121B）的发酵液中回收的BMY-28121抑制革兰氏阳性菌和厌氧菌，并抑制哺乳动物肿瘤的生长，例如 P-388白血病，L-1210白血病和B16黑素瘤。
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公开(公告)号：US4683230A
公开(公告)日：1987-07-28
申请号：US704973
申请日：1985-02-25
IPC分类号： C07D487/04 , C12P17/18 , A61K31/55
CPC分类号： C07D487/04 , C12P17/182 , C12R1/47
摘要： A new antitumor antibiotic designated herein as BMY-28121 is produced by fermentation of Streptomyces albus strain K731-113 (ATCC 39897). BMY-28121, which may be recovered from the fermentation broth in either its natural free hydroxy form (BMY-28121A) or methyl ether form (BMY-28121B), inhibits gram-positive bacteria and anaerobes and inhibits the growth of mammalian tumors such as P-388 leukemia, L-1210 leukemia and B16 melanoma.
摘要翻译： 本文命名为BMY-28121的新型抗肿瘤抗生素通过Streptomyces albus菌株K731-113（ATCC 39897）的发酵产生。 可以从其天然游离羟基形式（BMY-28121A）或甲基醚形式（BMY-28121B）的发酵液中回收的BMY-28121抑制革兰氏阳性菌和厌氧菌，并抑制哺乳动物肿瘤的生长，例如 P-388白血病，L-1210白血病和B16黑素瘤。
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9.发明授权Process and microorganisms for production of lipids from lignocellulosic wastes or residues 有权从木质纤维素废物或残留物生产脂质的工艺和微生物公开(公告)号：US08697403B2
公开(公告)日：2014-04-15
申请号：US13114756
申请日：2011-05-24
CPC分类号： C12P7/649 , C12N1/38 , C12N9/1029 , C12N9/99 , C12P7/6463 , C12R1/465 , C12R1/47 , C12R1/545 , Y02E50/13
摘要： Disclosed are processes for producing lipids for biofuel or lubricant and Streptomyces bacteria used in the processes. The processes include steps whereby bacterial cells of the germs Streptomyces are cultivated in a medium comprising organic waste(s) or residue(s) or mixtures thereof as carbon and/or nutrient source(s), wherein the organic waste(s) or residue(s) comprise lignocellulosic waste(s) or lignocellulosic residue(s), recovering lipids from the cells of the bacteria or from the cultivation medium, and using the recovered lipids or a fraction thereof as biofuel and/or lubricant, or as a starting material for biofuel and/or lubricant production.
摘要翻译： 公开了用于生产生物燃料或润滑剂的脂质和用于该方法的链霉菌属细菌的方法。 该方法包括以下步骤，其中细菌链霉菌的细菌细胞在包含有机废物或其残留物或其混合物的培养基中培养为碳和/或营养源，其中有机废物或残留物 或由木质纤维素废物或木质纤维素残留物，从细菌细胞或培养基中回收脂质，并使用回收的脂质或其部分作为生物燃料和/或润滑剂，或作为起始物 用于生物燃料和/或润滑剂生产的材料。
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公开(公告)号：US20110294173A1
公开(公告)日：2011-12-01
申请号：US13114756
申请日：2011-05-24
CPC分类号： C12P7/649 , C12N1/38 , C12N9/1029 , C12N9/99 , C12P7/6463 , C12R1/465 , C12R1/47 , C12R1/545 , Y02E50/13
摘要： The present invention provides a process for producing lipids for biofuel or lubricant and Streptomyces bacteria used in the process. The process comprises cultivating bacterial cells of the genus Streptomyces in a medium comprising organic waste(s) or residue(s) or mixtures thereof as carbon and/or nutrient source(s), recovering lipids from the cells of said bacteria or from the cultivation medium, and using the recovered lipids or a fraction thereof as biofuel and/or lubricant, or as a starting material for biofuel and/or lubricant production.In addition, in one aspect the invention provides products obtained by using the process according to this disclosure.
摘要翻译： 本发明提供一种用于生产生物燃料或润滑剂的脂质的方法以及在该方法中使用的链霉菌。 该方法包括在包含有机废物或其残留物或其混合物作为碳和/或营养源的培养基中培养链霉菌属的细菌细胞，从所述细菌的细胞或培养物中回收脂质 并且使用回收的脂质或其一部分作为生物燃料和/或润滑剂，或作为生物燃料和/或润滑剂生产的起始材料。 此外，在一个方面，本发明提供通过使用根据本公开的方法获得的产物。
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