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公开(公告)号：WO2005107762A3
公开(公告)日：2006-08-17
申请号：PCT/US2005015666
申请日：2005-05-06
申请人： CYTOKINETICS INC , SMITHKLINE BEECHAM CORP , QIAN XIANGPING , MCDONALD ANDREW I , ZHOU HAN-JIE , ASHCRAFT LUKE W , YAO BING , JIANG HONG , HUANG JENNIFER KUO CHEN , WANG JIANCHAO , MORGANS DAVID J JR , MORGAN BRADLEY P , BERGNES GUSTAVE , DHANAK DASHYANT , KNIGHT STEVEN D , ADAMS NICHOLAS D , PARRISH CYNTHIA A , DUFFY KEVIN , FITCH DUKE , TEDESCO ROSANNA
发明人： QIAN XIANGPING , MCDONALD ANDREW I , ZHOU HAN-JIE , ASHCRAFT LUKE W , YAO BING , JIANG HONG , HUANG JENNIFER KUO CHEN , WANG JIANCHAO , MORGANS DAVID J JR , MORGAN BRADLEY P , BERGNES GUSTAVE , DHANAK DASHYANT , KNIGHT STEVEN D , ADAMS NICHOLAS D , PARRISH CYNTHIA A , DUFFY KEVIN , FITCH DUKE , TEDESCO ROSANNA
IPC分类号： C07C233/65 , A61K31/165 , A61K31/4184 , A61K31/4196 , A61K31/421 , A61K31/424 , A61K31/4745 , A61K31/55 , C07C235/48 , C07C235/50 , C07C235/52 , C07C237/22 , C07C255/57 , C07C257/18 , C07C259/18 , C07C271/20 , C07C271/28 , C07C275/40 , C07C281/06 , C07C311/37 , C07D207/26 , C07D207/273 , C07D211/76 , C07D213/30 , C07D231/12 , C07D235/18 , C07D235/26 , C07D261/08 , C07D263/10 , C07D271/06 , C07D277/56 , C07D285/02 , C07D295/155 , C07D333/38 , C07D403/10 , C07D403/12 , C07D471/04 , C07D487/02 , C07D491/02 , C07F9/6506 , C07F9/6561
CPC分类号： C07D403/12 , C07C235/48 , C07C235/50 , C07C235/52 , C07C237/22 , C07C255/57 , C07C257/18 , C07C259/18 , C07C271/20 , C07C271/28 , C07C275/40 , C07C281/06 , C07C311/37 , C07C2601/14 , C07D207/273 , C07D211/76 , C07D213/30 , C07D231/12 , C07D233/62 , C07D235/18 , C07D235/26 , C07D261/08 , C07D263/10 , C07D271/06 , C07D277/56 , C07D285/02 , C07D295/155 , C07D333/38 , C07D403/10 , C07D471/04 , C07F9/65062 , C07F9/6561
摘要： Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed.
摘要翻译： 公开了通过调节一种或多种有丝分裂驱动蛋白的活性来治疗细胞增殖性疾病和病症的化合物。
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公开(公告)号：WO2005107762A2
公开(公告)日：2005-11-17
申请号：PCT/US2005/015666
申请日：2005-05-06
申请人： CYTOKINETICS, INC. , SMITHKLINE BEECHAM CORPORATION , QIAN, Xiangping , MCDONALD, Andrew, I. , ZHOU, Han-Jie , ASHCRAFT, Luke, W. , YAO, Bing , JIANG, Hong , HUANG, Jennifer, Kuo, Chen , WANG, Jianchao , MORGANS, David, J., Jr. , MORGAN, Bradley, P. , BERGNES, Gustave , DHANAK, Dashyant , KNIGHT, Steven, D. , ADAMS, Nicholas, D. , PARRISH, Cynthia, A.
发明人： QIAN, Xiangping , MCDONALD, Andrew, I. , ZHOU, Han-Jie , ASHCRAFT, Luke, W. , YAO, Bing , JIANG, Hong , HUANG, Jennifer, Kuo, Chen , WANG, Jianchao , MORGANS, David, J., Jr. , MORGAN, Bradley, P. , BERGNES, Gustave , DHANAK, Dashyant , KNIGHT, Steven, D. , ADAMS, Nicholas, D. , PARRISH, Cynthia, A.
IPC分类号： A61K31/55
CPC分类号： C07D403/12 , C07C235/48 , C07C235/50 , C07C235/52 , C07C237/22 , C07C255/57 , C07C257/18 , C07C259/18 , C07C271/20 , C07C271/28 , C07C275/40 , C07C281/06 , C07C311/37 , C07C2601/14 , C07D207/273 , C07D211/76 , C07D213/30 , C07D231/12 , C07D233/62 , C07D235/18 , C07D235/26 , C07D261/08 , C07D263/10 , C07D271/06 , C07D277/56 , C07D285/02 , C07D295/155 , C07D333/38 , C07D403/10 , C07D471/04 , C07F9/65062 , C07F9/6561
摘要： Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed.
摘要翻译： 公开了通过调节一种或多种有丝分裂驱动蛋白的活性来治疗细胞增殖性疾病和病症的化合物。
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公开(公告)号：WO2007056469A3
公开(公告)日：2007-11-15
申请号：PCT/US2006043514
申请日：2006-11-08
申请人： CYTOKINETICS INC , SMITHKLINE BEECHAM CORP , QIAN XIANGPING , ASHCRAFT LUKE W , WANG JIANCHAO , YAO BING , JIANG HONG , BERGNES GUSTAVE , MORGAN BRADLEY P , MORGANS DAVID J JR , DHANAK DASHYANT , KNIGHT STEVEN D , ADAMS NICHOLAS D , PARRISH CYNTHIA A , DUFFY KEVIN J , FITCH DUKE M , TEDESCO ROSANNA
发明人： QIAN XIANGPING , ASHCRAFT LUKE W , WANG JIANCHAO , YAO BING , JIANG HONG , BERGNES GUSTAVE , MORGAN BRADLEY P , MORGANS DAVID J JR , DHANAK DASHYANT , KNIGHT STEVEN D , ADAMS NICHOLAS D , PARRISH CYNTHIA A , DUFFY KEVIN J , FITCH DUKE M , TEDESCO ROSANNA
IPC分类号： C07D419/00 , A61K31/4184 , A61K31/4196 , A61K31/421 , A61K31/424 , A61K31/4745 , A61K31/53 , A61K31/55 , C07C235/48 , C07C235/50 , C07C235/52 , C07C237/22 , C07C255/57 , C07C257/18 , C07C259/18 , C07C271/20 , C07C271/28 , C07C275/40 , C07C281/06 , C07C311/37 , C07D207/26 , C07D207/273 , C07D211/76 , C07D213/30 , C07D231/12 , C07D235/18 , C07D235/26 , C07D261/08 , C07D263/10 , C07D271/06 , C07D277/56 , C07D285/02 , C07D295/155 , C07D333/38 , C07D403/10 , C07D403/12 , C07D471/04 , C07D487/02 , C07D491/02 , C07F9/6506 , C07F9/6561
CPC分类号： C07D233/64 , C07C235/48 , C07C235/50 , C07C235/52 , C07C237/22 , C07C255/57 , C07C255/59 , C07C255/60 , C07C257/08 , C07C257/18 , C07C259/18 , C07C271/20 , C07C271/24 , C07C271/28 , C07C275/26 , C07C275/40 , C07C275/42 , C07C281/06 , C07C307/10 , C07C311/37 , C07C311/46 , C07C2601/02 , C07C2601/14 , C07D207/273 , C07D211/34 , C07D211/76 , C07D213/30 , C07D231/12 , C07D231/14 , C07D233/61 , C07D233/70 , C07D235/06 , C07D235/16 , C07D235/18 , C07D235/26 , C07D239/36 , C07D249/08 , C07D257/04 , C07D261/08 , C07D263/10 , C07D263/12 , C07D263/32 , C07D271/06 , C07D271/07 , C07D271/10 , C07D271/113 , C07D277/30 , C07D277/42 , C07D277/56 , C07D285/02 , C07D285/125 , C07D295/145 , C07D295/155 , C07D333/38 , C07D403/10 , C07D403/12 , C07D413/06 , C07D471/04 , C07D498/04 , C07F9/65062 , C07F9/6561
摘要： Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed.
摘要翻译： 公开了通过调节一种或多种有丝分裂驱动蛋白的活性来治疗细胞增殖性疾病和病症的化合物。
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公开(公告)号：WO2007056469A2
公开(公告)日：2007-05-18
申请号：PCT/US2006/043514
申请日：2006-11-08
申请人： CYTOKINETICS, INC. , SMITHKLINE BEECHAM CORPORATION , QIAN, Xiangping , ASHCRAFT, Luke, W. , WANG, Jianchao , YAO, Bing , JIANG, Hong , BERGNES, Gustave , MORGAN, Bradley, P. , MORGANS, David, J., Jr. , DHANAK, Dashyant , KNIGHT, Steven, D. , ADAMS, Nicholas, D. , PARRISH, Cynthia, A. , DUFFY, Kevin, J. , FITCH, Duke, M. , TEDESCO, Rosanna
发明人： QIAN, Xiangping , ASHCRAFT, Luke, W. , WANG, Jianchao , YAO, Bing , JIANG, Hong , BERGNES, Gustave , MORGAN, Bradley, P. , MORGANS, David, J., Jr. , DHANAK, Dashyant , KNIGHT, Steven, D. , ADAMS, Nicholas, D. , PARRISH, Cynthia, A. , DUFFY, Kevin, J. , FITCH, Duke, M. , TEDESCO, Rosanna
IPC分类号： A61K31/4184 , A61K31/4172 , C07D233/61
CPC分类号： C07D233/64 , C07C235/48 , C07C235/50 , C07C235/52 , C07C237/22 , C07C255/57 , C07C255/59 , C07C255/60 , C07C257/08 , C07C257/18 , C07C259/18 , C07C271/20 , C07C271/24 , C07C271/28 , C07C275/26 , C07C275/40 , C07C275/42 , C07C281/06 , C07C307/10 , C07C311/37 , C07C311/46 , C07C2601/02 , C07C2601/14 , C07D207/273 , C07D211/34 , C07D211/76 , C07D213/30 , C07D231/12 , C07D231/14 , C07D233/61 , C07D233/70 , C07D235/06 , C07D235/16 , C07D235/18 , C07D235/26 , C07D239/36 , C07D249/08 , C07D257/04 , C07D261/08 , C07D263/10 , C07D263/12 , C07D263/32 , C07D271/06 , C07D271/07 , C07D271/10 , C07D271/113 , C07D277/30 , C07D277/42 , C07D277/56 , C07D285/02 , C07D285/125 , C07D295/145 , C07D295/155 , C07D333/38 , C07D403/10 , C07D403/12 , C07D413/06 , C07D471/04 , C07D498/04 , C07F9/65062 , C07F9/6561
摘要： Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed.
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