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公开(公告)号:US20250003949A1
公开(公告)日:2025-01-02
申请号:US18739556
申请日:2024-06-11
Applicant: Hamamatsu Photonics K.K.
Inventor: Tokio TAKAGI , Toyohiko YAMAUCHI , Tatsuo DOUGAKIUCHI , Yoichi KAWADA , Yoshiyuki SHIMIZU , Gen TAKEBE
IPC: G01N33/483 , G01N1/28 , G01N1/30 , G01N21/64
Abstract: A cell sample measurement apparatus includes a sample stage for placing an object cell sample containing a plurality of cells cultured on a culture dish, an evaluation light irradiation unit for irradiating N irradiation regions set by dividing a culture region in the object cell sample with evaluation light having a wavelength in a mid-infrared region with irradiation amounts different from each other, a dead cell number measurement unit for measuring a dead cell number generated according to the irradiation amount of the evaluation light in each of the N irradiation regions, and a culture state analysis unit for obtaining, for the object cell sample, an object correlation between the irradiation amount of the evaluation light and the dead cell number for the N irradiation regions serving as an index of evaluation of a culture state of the object cell sample.
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公开(公告)号:US20240068866A1
公开(公告)日:2024-02-29
申请号:US18237594
申请日:2023-08-24
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Tatsuo DOUGAKIUCHI
CPC classification number: G01J3/021 , G01J3/0208 , G01J3/0289 , G01J3/427 , G01J2003/423
Abstract: The spectrometer includes: a light source unit emitting a laser beam; a mirror unit including a first plane mirror having a first mirror surface and a second plane mirror having a second mirror surface, wherein a measurement target is introduced between the first mirror surface and the second mirror surface; and a light detector detecting the laser beam returned by multiple reflection between the first mirror surface and the second mirror surface. The first mirror surface and the second mirror surface are arranged non-parallel to each other when viewed from the Z-axis direction so as to form an optical path of the laser beam reciprocating in the Y-axis direction while performing multiple reflection between the first mirror surface and the second mirror surface. The optical path of the laser beam between the first mirror surface and the second mirror surface is inclined with respect to the Z-axis direction.
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公开(公告)号:US20180236257A1
公开(公告)日:2018-08-23
申请号:US15896267
申请日:2018-02-14
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Gen TAKEBE , Yoshiyuki SHIMIZU , Toyohiko YAMAUCHI , Tatsuo DOUGAKIUCHI
CPC classification number: A61N5/062 , A61N5/0622 , A61N2005/0659 , C12M35/02 , C12N13/00 , C12N2529/10
Abstract: A cell stimulation method includes continuously emitting mid-infrared light to a living cell and thus changing an ion concentration of the cell or changing ion concentrations of the cell and other cells disposed around the cell.
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公开(公告)号:US20220209505A1
公开(公告)日:2022-06-30
申请号:US17608225
申请日:2020-12-16
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Kazuue FUJITA , Shohei HAYASHI , Hiroyasu FUJIWARA , Atsushi NAKANISHI , Akio ITO , Tatsuo DOUGAKIUCHI
Abstract: A laser module including a quantum cascade laser that includes a substrate having a main surface, a first clad layer provided on the main surface, an active layer provided on the first clad layer, and a second clad layer provided on the active layer, and a lens that has a lens plane disposed at a position facing the end surface of the active layer. An end surface of the active layer constitutes a resonator that causes light of a first frequency and light of a second frequency to oscillate, and the active layer is configured to generate a terahertz wave of a differential frequency between the first frequency and the second frequency. The substrate is in direct contact or indirect contact with the lens plane, and the end surface of the active layer is inclined with respect to a portion facing the end surface in the lens plane.
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公开(公告)号:US20210181518A1
公开(公告)日:2021-06-17
申请号:US17108278
申请日:2020-12-01
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Takahide OCHIAI , Naota AKIKUSA , Tatsuo DOUGAKIUCHI , Tadataka EDAMURA
Abstract: A light source module includes a light source; an optical fiber configured to guide light output from the light source; a pair of holding members configured to hold both ends of a first portion of the optical fiber such that the first portion extends linearly; a first vibrator configured to vibrate the first portion along a first direction intersecting an extending direction of the first portion; and a second vibrator configured to vibrate the first portion along a second direction intersecting the extending direction and differing from the first direction.
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公开(公告)号:US20190265396A1
公开(公告)日:2019-08-29
申请号:US16285426
申请日:2019-02-26
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Tadataka EDAMURA , Atsushi SUGIYAMA , Tatsuo DOUGAKIUCHI
IPC: G02B5/18
Abstract: A movable diffraction grating includes; a supporting portion; a movable portion which includes a first surface and is swingably connected with the supporting portion; a resin layer which is provided on the first surface and includes a diffraction grating pattern formed therein; a reflection layer which is provided on the resin layer an along the diffraction grating pattern and is formed of metal; and a stress regulation portion inducing stress on the movable portion, and the first surface is caused to bend concavely by stress.
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公开(公告)号:US20170063044A1
公开(公告)日:2017-03-02
申请号:US15251119
申请日:2016-08-30
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Tatsuo DOUGAKIUCHI , Kazuue FUJITA , Akio ITO , Tadataka EDAMURA
CPC classification number: H01S5/3402 , H01S5/0267 , H01S5/0604 , H01S5/1028 , H01S5/1096 , H01S5/1221 , H01S5/124 , H01S5/141 , H01S5/18 , H01S5/2018 , H01S2302/02
Abstract: A quantum cascade laser is configured with a semiconductor substrate, and an active layer provided on a first surface of the substrate and having a multistage lamination of unit laminate structures each of which includes an emission layer and an injection layer. The active layer is configured to be capable of generating first pump light of a frequency ω1 and second pump light of a frequency ω2, and to generate output light of a difference frequency ω by difference frequency generation. An external diffraction grating is provided constituting an external cavity for generating the first pump light and configured to be capable of changing the frequency ω1, outside an element structure portion including the active layer. Grooves respectively formed in a direction intersecting with a resonating direction are provided on a second surface of the substrate.
Abstract translation: 量子级联激光器被配置为具有半导体衬底和设置在衬底的第一表面上的有源层,并且具有包括发射层和注入层的单元层叠结构的多级叠层。 有源层被配置为能够产生频率ω1的第一泵浦光和频率ω2的第二泵浦光,并且通过差频产生产生差频ω的输出光。 提供外部衍射光栅,其构成用于产生第一泵浦光的外部空腔,并且被配置为能够在包括有源层的元件结构部分外部改变频率ω1。 分别在与谐振方向相交的方向上形成的槽设置在基板的第二表面上。
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公开(公告)号:US20250079805A1
公开(公告)日:2025-03-06
申请号:US18822534
申请日:2024-09-03
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Hisanari TAKAHASHI , Kazuue FUJITA , Tatsuo DOUGAKIUCHI
IPC: H01S5/34 , G01N21/3581
Abstract: A terahertz wave detection device includes a QCL element, an optical component disposed such that a laser beam emitted from the QCL element passes, and a photodetector that detects the laser beam having passed through the optical component. The QCL element has a semiconductor layer including an active layer in which unit stacked bodies including a light emitting layer and an injection layer are stacked in multiple stages. The unit stacked body is configured to be able to oscillate a first laser beam having a first wavelength and a second laser beam having a second wavelength. The QCL element is configured to change oscillation degrees of the first and second laser beams in accordance with the incidence of the terahertz wave on the QCL element. The optical component is configured to cause either one of the first laser beam and the second laser beam to be incident on the photodetector.
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公开(公告)号:US20230317867A1
公开(公告)日:2023-10-05
申请号:US18023435
申请日:2021-05-26
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Tatsuo DOUGAKIUCHI , Akio ITO , Masahiro HITAKA , Tadataka EDAMURA
IPC: H01L31/0352 , H01L23/482 , H01L31/02 , H01L31/0232 , H01L31/0304 , G01J3/10 , G01J3/45 , G01J3/457
CPC classification number: H01L31/035236 , H01L23/4821 , H01L31/02005 , H01L31/02325 , H01L31/035281 , H01L31/03046 , G01J3/10 , G01J3/45 , G01J3/457 , G01J2003/102
Abstract: A photodetection module includes a photodetector and a fixing member. The photodetector includes a semiconductor substrate, a mesa portion, a first contact layer, a second contact layer, and a first electrode formed in a planar shape on a major surface of the semiconductor substrate, and electrically connected to one of the first contact layer and the second contact layer. The fixing member includes an insulating substrate, and a first wiring formed in a planar shape on a major surface of the insulating substrate. A recessed portion is formed in the major surface of the insulating substrate, and at least a part of the mesa portion is disposed inside the recessed portion. The first electrode is electrically connected to the first wiring in a state where the first electrode is in surface contact with the first wiring.
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公开(公告)号:US20230246418A1
公开(公告)日:2023-08-03
申请号:US18023773
申请日:2021-06-07
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Atsushi SUGIYAMA , Tatsuo DOUGAKIUCHI
CPC classification number: H01S5/143 , H01S5/3401 , H01S5/02415
Abstract: The external cavity laser module includes a quantum cascade laser element, a MEMS diffraction grating, a support plate having a first surface on which the quantum cascade laser element and the MEMS diffraction grating are disposed and a second surface opposite to the first surface, and a cooling element disposed on a side facing the second surface of the support plate to overlap with the quantum cascade laser element and the MEMS diffraction grating. In the second surface of the support plate, a concave portion recessed in a direction from the second surface toward the first surface is provided in at least a region overlapping with the quantum cascade laser element and the MEMS diffraction grating when viewed from the thickness direction. At least a portion of the cooling element facing the support plate is inserted into the concave portion.
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