公开(公告)号：US20110075708A1

公开(公告)日：2011-03-31

申请号：US12575879

申请日：2009-10-08

Applicant: Mark Hahm ,  Wei Luo ,  Bin Liu ,  Jun Wu ,  Severine Catreux-Erceg ,  Shuangquan Wang

Inventor： Mark Hahm ,  Wei Luo ,  Bin Liu ,  Jun Wu ,  Severine Catreux-Erceg ,  Shuangquan Wang

IPC: H04L1/02 ,  H04B1/707

CPC classification number: H04B1/711 ,  H04B1/71072 ,  H04B1/712 ,  H04J13/0044

Abstract: A wireless system may receive a plurality of multipath signals from a plurality of transmitters and allocate per-cell modules for generating an interference suppressed signal from the multipath signals. Data symbols may be sequentially processed in the received multipath signals utilizing the per-cell modules and subtracting the processed symbols from a residual buffer storing the received multipath signals. Desired information received from one or more of the transmitters may be recovered utilizing the interference suppressed signal. Timing of the data symbols may be correlated utilizing a cell chip combiner. The data symbols may be descrambled utilizing conjugated scrambling codes associated with one of the plurality of transmitters. Orthogonal variable spreading factor (OVSF) codes may be generated utilizing a Walsh transform on the data symbols. Power levels of the OVSF codes may be estimated and estimated signals may be generated based on the OVSF codes and the estimated power levels.

Abstract translation: 无线系统可以从多个发射机接收多个多径信号，并且分配用于从多路径信号产生干扰抑制信号的每小区模块。 数据符号可以利用每个单元模块在所接收的多路径信号中被顺序地处理，并且从存储所接收的多径信号的残差缓冲器中减去经处理的符号。 可以使用干扰抑制信号来恢复从一个或多个发射机接收到的期望信息。 数据符号的定时可以利用单元芯片组合器进行相关。 数据符号可以利用与多个发射机之一相关联的共轭扰码进行解扰。 可以使用对数据符号的沃尔什变换来生成正交可变扩展因子（OVSF）码。 可以估计OVSF码的功率电平，并且可以基于OVSF码和估计功率电平来生成估计信号。

公开(公告)号：US07897684B2

公开(公告)日：2011-03-01

申请号：US11329495

申请日：2006-01-10

Applicant: Guillermo C. Bazan ,  Bin Liu

Inventor： Guillermo C. Bazan ,  Bin Liu

IPC: C08G63/91 ,  C08G63/00 ,  C12Q1/68

CPC classification number: C08G61/02 ,  C08G61/122 ,  C08G61/123 ,  C12Q1/6818 ,  C12Q1/6837 ,  G01N21/6428 ,  G01N21/6452 ,  G01N2021/6419 ,  G01N2021/6439 ,  C12Q2563/131 ,  C12Q2537/119 ,  C12Q2525/107

Abstract: The invention further relates to polycationic multichromophores, which may be conjugated polymers, and methods, articles and compositions employing them as described herein. In some aspects, the invention relates to methods, articles and compositions for the detection and analysis of biomolecules in a sample. Provided assays include those determining the presence of a target biomolecule in a sample or its relative amount, or the assays may be quantitative or semi-quantitative. The methods can be performed on a substrate. The methods can be performed in an array format on a substrate, which can be a sensor. In some embodiments, detection assays are provided employing sensor biomolecules that do not comprise a fluorophore that can exchange energy with the cationic multichromophore. In some aspects biological assays are provided in which energy is transferred between one or more of the multichromophore, a label on the target biomolecule, a label on the sensor biomolecule, and/or a fluorescent dye specific for a polynucleotide, in all permutations. The multichromophore may interact at least in part electrostatically with the sensor and/or the target, and an increase in energy transfer with the polymer may occur upon binding of the sensor and the target. Other variations of the inventions are described further herein.

Abstract translation: 本发明还涉及可以是共轭聚合物的阳离子多色素，以及如本文所述使用它们的方法，制品和组合物。 在一些方面，本发明涉及用于检测和分析样品中生物分子的方法，制品和组合物。 提供的测定包括确定样品中靶生物分子的存在或其相对量的那些，或者测定可以是定量或半定量的。 该方法可以在衬底上进行。 这些方法可以以阵列格式在基底上进行，其可以是传感器。 在一些实施方案中，使用不包含能够与阳离子多重色素交换能量的荧光团的传感器生物分子来提供检测测定。 在一些方面，提供生物测定，其中在所有置换中，能量在一个或多个多色素，目标生物分子上的标记，传感器生物分子上的标记和/或多核苷酸特异的荧光染料之间转移。 多重色淀可以至少部分地与传感器和/或靶相互作用，并且当传感器和目标物结合时，聚合物的能量传递的增加可能发生。 本文进一步描述了本发明的其它变型。

公开(公告)号：US20110029942A1

公开(公告)日：2011-02-03

申请号：US12845204

申请日：2010-07-28

Applicant: Bin LIU ,  Zhiru ZHANG ,  Jason CONG

Inventor： Bin LIU ,  Zhiru ZHANG ,  Jason CONG

IPC: G06F17/50

CPC classification number: G06F17/505

Abstract: A method for implementing soft constraints in scheduling comprises receiving a description of circuit behavior. The description is un-timed. A scheduling solution is generated for use in scheduling the description. The scheduling solution includes scheduling variables and an objective function. The scheduling variables schedule the time of at least one operation. The objective function includes a penalty term and constraints comprising at least one hard constraint and at least one soft constraint. The constraints are created on the scheduling variables. The penalty term comprises a slack variable representing violations of the constraints. The penalty term measures the design cost of violating the soft constraint. Following generation of the scheduling solution, the description is scheduled by applying the scheduling solution to the description. Timing information of the description is provided as an output of the scheduling.

Abstract translation: 用于在调度中实现软约束的方法包括接收电路行为的描述。 描述是不及时的。 生成调度解决方案用于调度描述。 调度解决方案包括调度变量和目标函数。 调度变量调度至少一个操作的时间。 目标函数包括惩罚项和包含至少一个硬约束和至少一个软约束的约束。 在调度变量上创建约束。 惩罚项包括表示违反约束的松弛变量。 罚款条款衡量违反软约束的设计成本。 在生成调度解决方案之后，通过将调度解决方案应用于描述来调度描述。 提供描述的定时信息作为调度的输出。

公开(公告)号：US20110027898A1

公开(公告)日：2011-02-03

申请号：US12903176

申请日：2010-10-12

Applicant: Guillermo C. BAZAN ,  Bin LIU

Inventor： Guillermo C. BAZAN ,  Bin LIU

IPC: G01N33/50

CPC classification number: C12Q1/6818 ,  C12Q2563/119 ,  C12Q2565/101 ,  C12Q2565/519 ,  C12Q2565/607 ,  C12Q2523/313

Abstract: The invention further relates to conjugated polymers, and methods, articles and compositions employing them as described herein. In some aspects, the invention relates to methods, articles and compositions for the detection and analysis of biomolecules in a sample. Provided assays include those determining the presence of a target biomolecule in a sample or its relative amount, or the assays may be quantitative or semi-quantitative. The methods can be performed on a substrate. The methods can be performed in an array format on a substrate, which can be a sensor. In some embodiments, detection assays are provided employing sensor biomolecules that do not comprise a fluorophore that can exchange energy with the cationic multichromophore. In some aspects biological assays are provided in which energy is transferred between one or more of the multichromophore, a label on the target biomolecule, a label on the sensor biomolecule, and/or a fluorescent dye specific for a polynucleotide, in all permutations. The multichromophore may interact at least in part electrostatically with the sensor and/or the target, and an increase in energy transfer with the polymer may occur upon binding of the sensor and the target. Other variations of the inventions are described further herein.

Abstract translation: 本发明还涉及共轭聚合物，以及如本文所述使用它们的方法，制品和组合物。 在一些方面，本发明涉及用于检测和分析样品中生物分子的方法，制品和组合物。 提供的测定包括确定样品中靶生物分子的存在或其相对量的那些，或者测定可以是定量或半定量的。 该方法可以在衬底上进行。 这些方法可以以阵列格式在基底上进行，其可以是传感器。 在一些实施方案中，使用不包含能够与阳离子多重色素交换能量的荧光团的传感器生物分子来提供检测测定。 在一些方面，提供生物测定，其中在所有置换中，能量在一个或多个多色素，目标生物分子上的标记，传感器生物分子上的标记和/或多核苷酸特异的荧光染料之间转移。 多重色淀可以至少部分地与传感器和/或靶相互作用，并且当传感器和目标物结合时，聚合物的能量传递的增加可能发生。 本文进一步描述了本发明的其它变型。

公开(公告)号：US20100255477A1

公开(公告)日：2010-10-07

申请号：US12711233

申请日：2010-02-23

Applicant: Guillermo C. BAZAN ,  Bin LIU

Inventor： Guillermo C. BAZAN ,  Bin LIU

IPC: C12Q1/68 ,  G01N21/00 ,  G01N33/53 ,  G01N33/68 ,  G01N33/48 ,  C08L81/00

CPC classification number: G01N21/6486 ,  C08G61/02 ,  C08G61/123 ,  C12Q1/6818 ,  C12Q1/6825 ,  G01N33/542 ,  G01N33/54373 ,  Y10T436/143333 ,  C12Q2565/113 ,  C12Q2563/173 ,  C12Q2565/101

Abstract: This invention relates to an aggregation sensor useful for the detection and analysis of aggregants in a sample, and methods, articles and compositions relating to such a sensor. The sensor comprises first and second optically active units, where energy may be transferred from an excited state of the first optically active unit to the second optically active unit. The second optically active unit is present in a lesser amount, but its relative concentration is increased upon aggregation, increasing its absorption of energy from the first optically active units. This increase in energy transfer can be detected in variety of formats to produce an aggregation sensing system for various aggregants, including for quantitation. Other variations of the inventions are described further herein.

Abstract translation: 本发明涉及可用于检测和分析样品中的聚集体的聚集传感器，以及与这种传感器相关的方法，制品和组合物。 传感器包括第一和第二光学有源单元，其中能量可以从第一光学活性单元的激发状态转移到第二光学活性单元。 第二光学活性单元以较小的量存在，但是其聚集时其相对浓度增加，从而增加其从第一光学活性单元的能量吸收。 可以以各种格式检测能量转移的这种增加，以产生用于各种聚合物的聚集感测系统，包括用于定量。 本文进一步描述了本发明的其它变型。

公开(公告)号：US07786145B2

公开(公告)日：2010-08-31

申请号：US10900706

申请日：2004-07-28

Applicant: Jie Fei Cheng ,  Bin Liu ,  Thomas Arrhenius ,  Mark E. Wilson ,  Alex M. Nadzan ,  Gary D. Lopaschuk ,  Jason R. Dyck ,  Rossy Serafimov

Inventor： Jie Fei Cheng ,  Bin Liu ,  Thomas Arrhenius ,  Mark E. Wilson ,  Alex M. Nadzan ,  Gary D. Lopaschuk ,  Jason R. Dyck ,  Rossy Serafimov

IPC: A61K31/4406 ,  A61K31/428 ,  A61K31/4025 ,  C07D417/12 ,  C07D277/72 ,  C07D207/14

CPC classification number: C07D277/70 ,  A61K31/428 ,  A61K31/4439 ,  A61K31/4745 ,  A61K31/506 ,  C07D417/12

Abstract: The present invention provides methods for the use of compounds as depicted by structure I, pharmaceutical compositions containing the same, and methods for the prophylaxis, management and treatment of metabolic diseases and diseases modulated by MCD inhibition. The compounds disclosed in this invention are useful for the prophylaxis, management and treatment of diseases involving in malonyl-CoA regulated glucose/fatty acid metabolism pathway. In particular, these compounds and pharmaceutical composition containing the same are indicated in the prophylaxis, management and treatment of cardiovascular diseases, diabetes, cancer and obesity.

Abstract translation: 本发明提供了使用结构I所示化合物的方法，含有该化合物的药物组合物，以及预防，治疗和治疗由MCD抑制调节的代谢疾病和疾病的方法。 本发明公开的化合物可用于预防，管理和治疗涉及丙二酰辅酶A调节的葡萄糖/脂肪酸代谢途径的疾病。 特别地，这些化合物和含有它们的药物组合物在心血管疾病，糖尿病，癌症和肥胖症的预防，治疗和治疗中被指出。

公开(公告)号：US20100102180A1

公开(公告)日：2010-04-29

申请号：US12488719

申请日：2009-06-22

Applicant: ZHI-BIN LIU ,  YI-QING LIU

Inventor： ZHI-BIN LIU ,  YI-QING LIU

IPC: F16M11/22 ,  F16M11/04

CPC classification number: F16M11/16 ,  F16M11/10 ,  F16M11/22 ,  F16M2200/08 ,  Y10S248/917

Abstract: A support stand for a flat-panel display monitor includes a hinge assembly and a support structure having a top end partially receiving the hinge assembly. The hinge assembly includes a first latching module. The first latching module includes an elastic member and a movable plate connected to the elastic member. The support structure includes a second latching module detachably connected to the first latching module. The second latching module includes a positioning plate having a latching portion extending from a bottom surface thereof. The latching portion is capable of latching with the movable plate. When the movable plate is pressed, the elastic member is deformed so that the second latching module is detached from the first latching module.

Abstract translation: 用于平板显示监视器的支撑架包括铰链组件和具有部分地接收铰链组件的顶端的支撑结构。 铰链组件包括第一闭锁模块。 第一闭锁模块包括弹性构件和连接到弹性构件的活动板。 支撑结构包括可拆卸地连接到第一闩锁模块的第二闩锁模块。 第二闭锁模块包括具有从其底表面延伸的闩锁部分的定位板。 闩锁部分能够与可动板闩锁。 当可动板被按压时，弹性部件变形，使得第二闩锁模块与第一锁定模块分离。

公开(公告)号：US20100025256A1

公开(公告)日：2010-02-04

申请号：US12504768

申请日：2009-07-17

Applicant: JONG-YI SU ,  CHENG-SHIN CHEN ,  REN-NING WANG ,  BIN LIU

Inventor： JONG-YI SU ,  CHENG-SHIN CHEN ,  REN-NING WANG ,  BIN LIU

IPC: C25D5/34 ,  C25D5/48

CPC classification number: C25D5/14 ,  C25D3/04 ,  C25D3/06 ,  C25D5/34 ,  C25D5/36

Abstract: A surface treatment method for housings comprising: providing a metal housing and pre-treating it to be cleaned; electroplating the housing to form a hexavalent chromium coating on the surface of the housing; and electroplating the housing to form a trivalent chromium coating on the hexavalent chromium coating.

Abstract translation: 一种用于壳体的表面处理方法，包括：提供金属壳体并对其进行预处理; 电镀外壳以在壳体的表面上形成六价铬涂层; 并电镀该外壳以在六价铬涂层上形成三价铬涂层。

公开(公告)号：US20100003267A1

公开(公告)日：2010-01-07

申请号：US12432528

申请日：2009-04-29

Applicant: Venkata Ramana Doppalapudi ,  Jing-Yu Lai ,  Bin Liu ,  Dingguo Liu ,  Joel Desharnais ,  Abhijit Suresh Bhat ,  Yanwen Fu ,  Bryan Douglas Oates ,  Gang Chen ,  Curt William Bradshaw

Inventor： Venkata Ramana Doppalapudi ,  Jing-Yu Lai ,  Bin Liu ,  Dingguo Liu ,  Joel Desharnais ,  Abhijit Suresh Bhat ,  Yanwen Fu ,  Bryan Douglas Oates ,  Gang Chen ,  Curt William Bradshaw

IPC: A61K39/395 ,  C07K14/00 ,  C07K19/00

CPC classification number: A61K47/48215 ,  A61K47/48246 ,  A61K47/48415 ,  A61K47/48507 ,  A61K47/60 ,  A61K47/64 ,  A61K47/6811 ,  A61K47/6835 ,  C07K14/71

Abstract: The present invention provides VEGF binding peptides. In addition, the invention provides VEGF peptides conjugated to antibodies alone and in conjunction with other anti-angiogenic molecules. Various uses of the peptides and compounds are provided, including methods to treat disorders associated with abnormal angiogenesis.

Abstract translation: 本发明提供VEGF结合肽。 此外，本发明提供了与单独的抗体和其它抗血管生成分子结合的VEGF肽。 提供肽和化合物的各种用途，包括治疗与异常血管发生相关的疾病的方法。

公开(公告)号：US07601356B2

公开(公告)日：2009-10-13

申请号：US11780627

申请日：2007-07-20

Applicant: Hong Jin ,  Bin Liu

Inventor： Hong Jin ,  Bin Liu

IPC: A61K39/145 ,  C12N7/04 ,  C12N15/44

CPC classification number: C12N7/00 ,  A61K39/12 ,  A61K39/145 ,  C07K14/005 ,  C12N2760/16121 ,  C12N2760/16122 ,  C12N2760/16134

Abstract: In certain aspects, the present invention provides methods for increasing the replication capacity of influenza viruses in hens' eggs and/or cell culture, recombinant and/or reassortant influenza viruses with increased replication capacity, and immunogenic and vaccine compositions comprising such recombinant and/or reassortant influenza viruses. In other aspects, the invention further provides nucleic acids encoding influenza genes associated with increased replication capacity, expression vectors comprising the nucleic acids of the invention, methods for making influenza viruses with increased replication capacity, and kits useful for practice of the methods.

Abstract translation: 在某些方面，本发明提供了增加在具有增加的复制能力的母鸡卵和/或细胞培养物，重组和/或重配流感病毒中的流感病毒的复制能力的方法，以及包含这种重组和/或 重配流感病毒。 在其它方面，本发明还提供编码与增加的复制能力相关的流感基因的核酸，包含本发明的核酸的表达载体，具有增加的复制能力的制备流感病毒的方法，以及可用于实施该方法的试剂盒。