-
公开(公告)号：US4879118A
公开(公告)日：1989-11-07
申请号：US168587
申请日：1988-03-03
IPC分类号： A61K31/19 , A61K9/70 , A61K31/135 , A61K31/16 , A61K31/165 , A61K31/215 , A61L15/44 , A61L15/58 , A61P17/00
CPC分类号： A61K9/7053 , A61K9/7061 , A61K9/7076 , A61L15/44 , A61L15/585 , A61L2300/21 , A61L2300/216
摘要： An antipruritic plaster prepared by spreading a medicament-containing adhesive mass on a backing, said medicament-containing adhesive mass being obtained by dissolving glycyrrhetinic acids in at least one solvent selected from benzyl alcohol, phenethyl alcohol, diphenhydramine, chlorpheniramine, N-methyl-2-pyrrolidone, crotamiton, and lauric acid diethanolamide and uniformly mixing the solution with a plaster base composed of a rubber compound adhesive plaster base, a tackifying agent, and a softener as the necessary components of a plaster base composed of an acrylic resin as the necessary component.
摘要翻译： 通过将含药物的粘合剂块铺展在背衬上制备的止痒膏，所述含药物的粘合剂块通过将甘草次酸溶解在选自苄醇，苯乙醇，苯海拉明，扑尔敏，N-甲基-2 - 吡咯烷酮，克罗他米通和月桂酸二乙醇酰胺，并将溶液与由橡胶复合物粘合剂膏剂，增粘剂和软化剂组成的石膏基料作为必要的由丙烯酸树脂构成的石膏基料的必要组分混合 零件。
-
公开(公告)号：US3349086A
公开(公告)日：1967-10-24
申请号：US32251763
申请日：1963-11-08
IPC分类号： A23K1/16 , A61L15/46 , C07D307/71 , C07D405/04 , C07D405/06
CPC分类号： C07D405/04 , A23K20/116 , A61L15/46 , A61L2300/204 , A61L2300/216 , C07D307/71 , C07D405/06
-
93.发明公开公开(公告)号：US20240342348A1
公开(公告)日：2024-10-17
申请号：US18632758
申请日：2024-04-11
CPC分类号： A61L33/0041 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/16 , A61L2300/204 , A61L2300/216 , A61L2300/416 , A61L2300/42 , A61L2300/61 , A61L2300/622 , A61L2300/802 , A61L2420/02 , A61L2420/08
摘要： A medical device may be coated with a therapeutic composition that includes a direct oral anticoagulant. An illustrative drug coating composition may comprise an excipient including polylactic acid (PLA), poly(lactic-co-glycolic acid) (PLGA), or poly(vinylidene fluoride)-co-hexafluoropropylene (PVDF-HFP) and a direct oral anticoagulant (DOAC). The illustrative drug coating may be applied to an outer surface of a medical device.
-
94.发明授权公开(公告)号：US11939431B2
公开(公告)日：2024-03-26
申请号：US17239092
申请日：2021-04-23
发明人： Yu-Chia Chang , Yunn-Kuen Chang , Wen-Yen Huang , Ging-Ho Hsiue , Hsieh-Chih Tsai , Shuian-Yin Lin , Nai-Sheng Hsu , Tzu-Yu Lin
CPC分类号： C08G81/00 , A61K31/337 , A61K47/34 , A61L31/041 , A61L31/06 , A61L31/16 , C08L71/02 , A61L2300/216 , A61L2300/416 , A61L2300/424
摘要： The present invention relates to a composition comprising an amino acid-modified polymer, a carboxypolysaccharide, and may further include a metal ion for anti-adhesion and vector application. More specifically, the invention relates to a thermosensitive composition having enhanced mechanical and improved water-erosion resistant properties for efficiently preventing tissue adhesions and can serve as a vector with bio-compatible, bio-degradable/absorbable, and in-vivo sustainable properties.
-
公开(公告)号：US11925547B2
公开(公告)日：2024-03-12
申请号：US17412124
申请日：2021-08-25
发明人： Tae Hyun Choi , Yan Lee , Ji Ung Park , Ji Yeon Ham , Hee Jin Kim , Suk Wha Kim , Hye Jeong Min
CPC分类号： A61F2/12 , A61F2/0059 , A61F2/0063 , A61L27/28 , A61L27/32 , A61L27/34 , B05D1/02 , A61F2002/0086 , A61F2002/009 , A61L2300/216 , A61L2400/18 , A61L2430/04 , C08F2/48
摘要： The present invention relates to a coating composition for an in-vivo implantable prosthesis including a photoinitiator, a crosslinking agent, and a phosphorylcholine (pc) monomer having an acrylate group, a method of coating an in-vivo implantable prosthesis using the coating composition, and a cosmetic prosthesis coated with the crosslinked polyphosphorylcholine.
An in-vivo implantable prosthesis coated with crosslinked polyphosphorylcholine may be manufactured by a simple method of applying a coating composition including a photoinitiator, a crosslinking agent, and a phosphorylcholine (pc) monomer having an acrylate group according to the present invention, and then irradiating uv rays. The crosslinked polyphosphorylcholine coating may provide hydrophilicity for the surface and may also remarkably reduce adsorption of proteins and fibroblasts, which may cause side effects such as capsular contracture. Further, the coating has strong enough not to peel off even under stimulation, and therefore, it is maintained under vigorous activity after implantation, thereby being usefully applied to the manufacture of an in-vivo implantable prosthesis with reduced side effects, such as breast prosthesis for cosmetic surgery.-
96.发明公开公开(公告)号：US20240050631A1
公开(公告)日：2024-02-15
申请号：US18016095
申请日：2021-07-14
CPC分类号： A61L29/085 , A61L29/126 , A61L29/16 , A61L2420/06 , A61L2300/114 , A61L2300/404 , A61L2300/216
摘要： Described herein are substrates, devices, methods for treating and preventing bacterial and fungal infections, such as infections associated with medical devices, and the like. Materials, substrates and devices of the present disclosure include materials, such as medical grade polymers, having a coating/layer of polyene antimycotic molecules coupled to a surface of the polymer substrate. In certain aspects, substrates and devices of the present disclosure also include a nitric oxide (NO) releasing material also embedded in/coated on the material. Methods of the present disclosure includes methods of making the compositions and/or devices of the present disclosure including materials functionalized with polyene antimycotic molecules and NO releasing materials. Embodiments also include methods of using the materials, substrates, and devices of the present disclosure to treat/prevent fungal and/or bacterial infections in a subject, particularly infections associated with the use of a medical device.
-
公开(公告)号：US20240042109A1
公开(公告)日：2024-02-08
申请号：US18280275
申请日：2022-03-29
发明人： Kun SUN , Jing SUN , Sun CHEN , Kai BAI , Yanan LU , Lu WANG , Fujun WANG , Fan ZHAO , Jihong HUANG
CPC分类号： A61L31/16 , A61L31/148 , A61L31/10 , A61L2300/626 , A61L2420/02 , A61L2300/416 , A61L2300/41 , A61L2300/216 , A61L2300/21 , A61L2300/802 , A61L2420/06
摘要： A preparation method of drug-loaded micelles of an absorbable vascular stent coating for angiostenosis in an infant is provided, including the following steps: Si: dissolving a drug to be encapsulated in an appropriate amount of an emulsifying agent, adding a chitosan-poly(p-dioxohone) amphiphilic block copolymer (chitosan-b-PPDO copolymer), and thoroughly mixing to obtain a drug-copolymer solution; S2: adding the drug-copolymer solution obtained in S1 dropwise to an emulsifying agent aqueous solution prepared in advance, and continuously stirring to obtain a stable drug-loaded micellar solution; and S3: removing the emulsifying agent from the micellar solution obtained in S2 through vacuum evaporation, stirring a resulting concentrate, and centrifuging the concentrate to obtain a supernatant; and filtering the supernatant to obtain a filtrate, and subjecting the filtrate to dialysis to obtain the drug-loaded micelles.
-
公开(公告)号：US11833271B2
公开(公告)日：2023-12-05
申请号：US17935773
申请日：2022-09-27
发明人： Qing Liu
IPC分类号： A61L27/36 , A61L24/00 , A61L15/44 , A61L15/20 , A61L27/54 , A61L27/52 , A61K33/38 , A61L15/40 , A61L27/02
CPC分类号： A61L27/3629 , A61K33/38 , A61L15/20 , A61L15/40 , A61L15/44 , A61L24/0005 , A61L24/0015 , A61L27/02 , A61L27/3687 , A61L27/3691 , A61L27/54 , A61L2300/104 , A61L2300/216 , A61L2300/404 , A61L2430/34
摘要： An antibacterial medical biomaterial includes an acellular small intestinal submucosal matrix material, an antibacterial gel layer located on a surface of the acellular small intestinal submucosal matrix material, and an absorbable fiber layer located on a surface of the antibacterial gel layer. Sulfadiazine silver is on the surface of the acellular small intestinal submucosal matrix material and/or within the acellular small intestinal submucosal matrix material. An absorbable fiber layer to which the sulfadiazine silver is attached, wherein the content of sulfadiazine silver in the absorbable fiber is 1 wt. %˜2 wt. %. The medical biomaterial is usable as an external medicine for treating wound infections relayed by burns or wounds, and for reducing the incidence of infection by using a conventional central venous catheter with a sulfadiazine silver antibacterial coating, so that the medical biomaterial loaded with sulfadiazine silver also has antibacterial activity consistent with sulfadiazine silver.
-
公开(公告)号：US11813181B2
公开(公告)日：2023-11-14
申请号：US16957941
申请日：2018-12-18
发明人： Wenjiao Lin , Wenchao Fu
CPC分类号： A61F2/82 , A61L31/022 , A61L31/06 , A61L31/088 , A61L31/148 , A61L31/16 , A61F2002/91575 , A61F2210/0004 , A61F2250/003 , A61F2250/0067 , A61L2300/21 , A61L2300/216 , A61L2300/40 , A61L2300/416 , A61L2420/06
摘要： An absorbable metal stent includes an absorbable metal substrate; the absorbable metal substrate includes a plurality of wave-shaped annular structures and a plurality of axial connecting portions, two ends of each axial connecting portion being connected to two adjacent wave-shaped annular structures, respectively, so as to axially connect the plurality of wave-shaped annular structures; a corrosion-promoting coating is formed on each axial connecting portion, the corrosion-promoting coating containing a corrosion-promoting substance, and the corrosion-promoting substance being selected from at least one of a degradable polymer and a degradable polymer antioxidant; the corrosion-promoting coatings cause the corrosion of the axial connecting portions to occur earlier than the corrosion of the plurality of wave-shaped annular structures. The absorbable metal stent has good bending performance and may prevent the problems of secondary hyperplasia after implantation and stenosis caused thereby.
-
公开(公告)号：US20190184064A1
公开(公告)日：2019-06-20
申请号：US15765090
申请日：2016-09-30
申请人： Robert DiLuccio , Paul Lorenc , Randy Milby
发明人： Robert DiLuccio , Paul Lorenc , Randy Milby
CPC分类号： A61L27/54 , A61L27/20 , A61L27/3834 , A61L27/58 , A61L2300/216 , A61L2300/252 , A61L2300/404 , A61L2300/414 , A61L2300/43 , A61L2300/64 , A61L2400/06 , A61L2430/34 , C08L5/08
摘要： A therapeutic filler composition and method of using the same for augmenting soft tissue is provided. The therapeutic filler composition may include an anti-microbial first component, a carrier, and a cross-linking agent, wherein the carrier is cross-linked with the cross-linking agent and the first component is combined with the cross-linked carrier into a combination having a therapeutic effect.
-
-
-
-
-
-
-
-
-
搜索结果
544 条记录 (耗时 0.017 秒)
