公开(公告)号：US09457174B2

公开(公告)日：2016-10-04

申请号：US14560194

申请日：2014-12-04

Applicant: VASCULAR DYNAMICS, INC.

Inventor： Yossi Gross

IPC: A61M29/02 ,  A61F2/82 ,  A61N1/05 ,  A61N1/32 ,  A61N1/36 ,  A61N1/375 ,  A61F2/856 ,  A61F2/06

CPC classification number: A61M29/02 ,  A61F2/82 ,  A61F2/856 ,  A61F2002/065 ,  A61F2230/0008 ,  A61F2250/0001 ,  A61F2250/0004 ,  A61N1/05 ,  A61N1/056 ,  A61N1/326 ,  A61N1/36017 ,  A61N1/36117 ,  A61N1/375

Abstract: Apparatus is provided for treating hypertension of a subject. The apparatus includes an implantable element which has a non-circular shape and which is configured to reduce the hypertension by facilitating an assumption of a non-circular shape by a blood vessel in a vicinity of a baroreceptor of the subject, during diastole of the subject. Other embodiments are also described.

Abstract translation: 提供用于治疗受试者的高血压的装置。 该装置包括可植入元件，其具有非圆形形状，并且构造成可以通过在受试者的舒张期期间通过受试者的压力感受器附近的血管促进假定非圆形形状来降低高血压 。 还描述了其它实施例。

公开(公告)号：US20160271390A1

公开(公告)日：2016-09-22

申请号：US15080343

申请日：2016-03-24

Applicant: Mark W. Kroll ,  Charles D. Swerdlow

Inventor： Mark W. Kroll ,  Charles D. Swerdlow

IPC: A61N1/08 ,  A61N1/39 ,  A61N1/05

CPC classification number: A61N1/08 ,  A61N1/056 ,  A61N1/0563 ,  A61N1/3621 ,  A61N1/37 ,  A61N1/3931 ,  A61N1/3956 ,  A61N1/3962 ,  A61N2001/083

Abstract: The present invention relates, generally, to scientific and medical system methods for diagnosis of implantable cardioverter defibrillator (ICD) lead conductor anomalies, in particular conductor migration and externalization within an ICD implantable cardiac lead. The method uses an “imaginary” component of the high frequency transmission line impedance having certain spectral changes that correspond to movements of the conductor or an “imaginary impedance”. This allows the detection of conductor migration and small insulation failures.

Abstract translation: 本发明一般涉及用于诊断植入式心律转复除颤器（ICD）引线导体异常的科学和医疗系统方法，特别是ICD可植入心脏引线内的导体迁移和外化。 该方法使用具有对应于导体的运动或“虚阻抗”的某些光谱变化的高频传输线阻抗的“虚部”分量。 这允许检测导体迁移和小绝缘故障。

公开(公告)号：US09446240B2

公开(公告)日：2016-09-20

申请号：US14516734

申请日：2014-10-17

Applicant: Interventional Autonomics Corporation

Inventor： Stephen C Masson ,  Terrance Ransbury ,  Richard S Stack ,  William E Sanders

IPC: A61N1/36 ,  A61N1/05

CPC classification number: A61N1/36117 ,  A61N1/0551 ,  A61N1/056 ,  A61N1/36053 ,  A61N1/36114 ,  A61N1/36135 ,  A61N1/36139

Abstract: A method of treating autonomic imbalance in a patient includes energizing a first therapeutic element disposed to deliver therapy to a parasympathetic nerve fiber (e.g. vagus nerve), and energizing a second therapeutic element to deliver therapy to a sympathetic cardiac nerve fiber. At least one of the therapeutic elements is disposed in the vasculature superior to the heart. The therapy decreases the patient's heart rate and elevates or maintains the blood pressure of the patient.

Abstract translation: 一种治疗患者自主神经不平衡的方法包括激发设置用于将副作用神经纤维（例如迷走神经）递送治疗的第一治疗元件，以及激励第二治疗元件以向交感神经纤维递送疗法。 至少一种治疗元件设置在优于心脏的脉管系统中。 该疗法可降低患者的心率，提高或维持患者的血压。

公开(公告)号：US09440091B2

公开(公告)日：2016-09-13

申请号：US14933112

申请日：2015-11-05

Applicant: St. Jude Medical, Atrial Fibrillation Division, Inc.

Inventor： Karin Jarverud ,  Cecilia Emmanuelsson ,  Anders Bjorling ,  Kjell Noren

IPC: A61N5/06 ,  A61N1/39 ,  A61N1/362 ,  A61B5/05 ,  A61B5/103 ,  A61B18/18 ,  A61N1/00 ,  A61B5/117 ,  A61N1/30

CPC classification number: A61N5/0613 ,  A61B5/0408 ,  A61B5/05 ,  A61B5/103 ,  A61B5/117 ,  A61B18/18 ,  A61B18/20 ,  A61B2018/00577 ,  A61N1/00 ,  A61N1/056 ,  A61N1/30 ,  A61N1/362 ,  A61N1/39 ,  A61N5/06 ,  A61N5/0603 ,  A61N2005/0602 ,  A61N2005/0609 ,  A61N2005/0612 ,  A61N2005/0626 ,  A61N2005/063 ,  A61N2005/0659 ,  A61N2005/0662

Abstract: In response to local or systemic inflammation in a patient, photobiomodulation therapy is applied to a cardiac location to reduce the risk and/or occurrence of cardiac arrhythmia. Once inflammation is identified, photobiomodulation therapy can be applied in any suitable fashion (e.g., via a catheter- or transesophageal probe-mounted photoemitter, via an externally-applied photoemitter, or via photoemitter incorporated into an implantable medical device). Photobiomodulation therapy can also be employed to good advantage in conjunction with non-photobiomodulation therapy (e.g., traditional cardiac rhythm management therapies).

公开(公告)号：US09433801B2

公开(公告)日：2016-09-06

申请号：US13527792

申请日：2012-06-20

Applicant: Li Qian ,  Chen Feng ,  Wen-Mei Zhao ,  Li Fan ,  Yu-Quan Wang ,  Liang Liu

Inventor： Li Qian ,  Chen Feng ,  Wen-Mei Zhao ,  Li Fan ,  Yu-Quan Wang ,  Liang Liu

IPC: A61N1/05 ,  A61N5/00 ,  A61N5/10 ,  H01B1/04 ,  B82Y5/00

CPC classification number: A61N5/1001 ,  A61N1/05 ,  A61N1/0529 ,  A61N1/056 ,  B82Y5/00 ,  H01B1/04

Abstract: A pacemaker is provided. The pacemaker includes a pulse generator and an electrode line connecting with the pulse generator. The electrode line includes at least one conductor. The at least one conductor includes at least one carbon nanotube wire having a plurality of radioactive particles therein.

Abstract translation: 提供起搏器。 起搏器包括脉冲发生器和与脉冲发生器连接的电极线。 电极线包括至少一个导体。 所述至少一个导体包括至少一个其中具有多个放射性粒子的碳纳米管线。

公开(公告)号：US09433368B2

公开(公告)日：2016-09-06

申请号：US14444069

申请日：2014-07-28

Applicant: Cardiac Pacemakers, Inc.

Inventor： Jeffrey E. Stahmann ,  William J. Linder ,  Keith R. Maile

IPC: A61N1/375 ,  A61N1/362 ,  A61B5/042 ,  A61N1/372

CPC classification number: A61N1/3756 ,  A61B5/042 ,  A61B5/0422 ,  A61B2562/0209 ,  A61N1/056 ,  A61N1/0587 ,  A61N1/3686 ,  A61N1/37205 ,  A61N1/375

Abstract: A leadless implantable medical device comprises a first electrode configured to deliver electrical pacing energy, a second electrode configured to sense intrinsic electrical cardiac activity, and a third electrode configurable to both deliver electrical pacing energy and sense intrinsic electrical cardiac activity. The first and third electrodes are used for delivering electrical pacing energy and the second and third electrodes are used to sense intrinsic electrical cardiac activity. None of the first, second and third electrodes are incorporated into a lead.

Abstract translation: 无引导植入式医疗装置包括构造成传递电起搏能量的第一电极，被配置为感测本征电心脏活动的第二电极，以及可配置为递送起搏能量并感测固有电心脏活动的第三电极。 第一和第三电极用于传递电起搏能量，第二和第三电极用于感测固有电心脏活动。 第一，第二和第三电极都不包含在引线中。

公开(公告)号：US09427588B2

公开(公告)日：2016-08-30

申请号：US14667240

申请日：2015-03-24

Applicant: Cardiac Pacemakers, Inc.

Inventor： Alok S. Sathaye ,  M. Jason Brooke ,  Bruce A. Tockman

IPC: A61B5/04 ,  H03H17/02 ,  A61N1/368 ,  A61N1/37 ,  A61N1/365 ,  A61N1/08 ,  A61N1/372 ,  A61N1/05

CPC classification number: A61N1/3686 ,  A61N1/056 ,  A61N1/08 ,  A61N1/36514 ,  A61N1/3702 ,  A61N1/3704 ,  A61N1/371 ,  A61N1/37223 ,  A61N1/37247 ,  A61N2001/083

Abstract: Approaches for selecting an electrode combination of multi-electrode pacing devices are described. Electrode combination parameters that support cardiac function consistent with a prescribed therapy are evaluated for each of a plurality of electrode combinations. Electrode combination parameters that do not support cardiac function are evaluated for each of the plurality of electrode combinations. An order is determined for the electrode combinations based on the parameter evaluations. An electrode combination is selected based on the order, and therapy is delivered using the selected electrode combination.

公开(公告)号：US09421025B2

公开(公告)日：2016-08-23

申请号：US14693155

申请日：2015-04-22

Applicant: SHOCKWAVE MEDICAL, INC.

Inventor： Daniel Hawkins ,  John M. Adams

IPC: A61B17/22 ,  A61M25/10 ,  A61N1/38 ,  A61N1/05

CPC classification number: A61B17/22022 ,  A61B2017/22025 ,  A61B2017/22054 ,  A61B2017/22061 ,  A61B2017/22062 ,  A61B2017/22068 ,  A61B2017/22098 ,  A61M25/1002 ,  A61M2025/1072 ,  A61N1/056 ,  A61N1/38

Abstract: A valvuloplasty system comprises a balloon adapted to be placed adjacent leaflets of a valve. The balloon is inflatable with a liquid. The system further includes a shock wave generator within the balloon that produces shock waves. The shock waves propagate through the liquid and impinge upon the valve to decalcify and open the valve.

公开(公告)号：US20160220828A1

公开(公告)日：2016-08-04

申请号：US15022374

申请日：2014-09-16

Applicant: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

Inventor： Ada Shuk Yan Poon ,  Alexander Jueshyan Yeh ,  Yuji Tanabe ,  John Ho ,  Sanghoek Kim

IPC: A61N1/378 ,  A61N1/36 ,  A61N1/365 ,  A61N1/05

CPC classification number: A61N1/3787 ,  A61B5/0008 ,  A61B5/0013 ,  A61B5/0031 ,  A61B5/0084 ,  A61B5/01 ,  A61B5/0215 ,  A61B5/026 ,  A61B5/04 ,  A61B5/14503 ,  A61B5/14539 ,  A61B5/14542 ,  A61B5/686 ,  A61B2560/0219 ,  A61H1/008 ,  A61H23/004 ,  A61H2201/1207 ,  A61M5/14276 ,  A61M31/002 ,  A61M2205/8206 ,  A61N1/0534 ,  A61N1/0551 ,  A61N1/056 ,  A61N1/3601 ,  A61N1/3605 ,  A61N1/36125 ,  A61N1/36139 ,  A61N1/362 ,  A61N1/365 ,  A61N1/37211 ,  A61N1/37229 ,  A61N1/3756 ,  A61N5/0601 ,  A61N7/00 ,  H01Q1/273 ,  H01Q9/0407 ,  H02J7/025 ,  H02J50/10 ,  H02J50/20 ,  H02J50/23

Abstract: Implantable devices and/or sensors can be wirelessly powered by controlling and propagating electromagnetic waves in a patient's tissue. Such implantable devices/sensors can be implanted at target locations in a patient, to stimulate areas such as the heart, brain, spinal cord, or muscle tissue, and/or to sense biological, physiological, chemical attributes of the blood, tissue, and other patient parameters. The propagating electromagnetic waves can be generated with sub-wavelength structures configured to manipulate evanescent fields outside of tissue to generate the propagating waves inside the tissue. Methods of use are also described.

公开(公告)号：US09399141B2

公开(公告)日：2016-07-26

申请号：US14180201

申请日：2014-02-13

Applicant: Medtronic, Inc.

Inventor： Bruce D Gunderson

IPC: A61N1/00 ,  A61N1/37 ,  A61N1/08 ,  A61N1/05

CPC classification number: A61N1/3706 ,  A61N1/056 ,  A61N1/08 ,  A61N2001/083

Abstract: A method and device for updating a frequency of determining whether a lead condition is occurring in a medical device that includes sensing a cardiac signal, determining the number of days the lead has been implanted prior to implanting of the medical device, performing a first update of a virtual lead days value associated with a number of days since implant of the lead in response to the determined number of days the lead has been implanted prior to implanting of the medical device, determining whether a lead condition is occurring in response to the sensed cardiac signal, and updating a frequency of determining whether the lead condition is occurring in response to the determined first update of the virtual lead days value.

Abstract translation: 一种用于更新确定包括感测心脏信号的医疗装置中的引导条件是否发生的频率的方法和装置，在植入医疗装置之前确定引导已被植入的天数，执行第一更新 与在植入植入医疗装置之前已经植入了铅的所确定的天数相关联的与导入铅相关联的天数的虚拟引导天数值，确定是否在检测到的心脏中发生引导条件 信号，以及响应于所确定的虚拟提前天数的第一更新来更新确定前导条件是否正在发生的频率。