公开(公告)号：US10077437B2

公开(公告)日：2018-09-18

申请号：US15189021

申请日：2016-06-22

Applicant: Yeda Research and Development Co. Ltd.

Inventor： Ron Milo ,  Arren Bar-Even ,  Elad Noor

IPC: C12N9/00 ,  C12N15/82 ,  C12N9/04 ,  C12N9/02 ,  C12N9/12 ,  C12N9/10 ,  C12N9/18 ,  C12N9/88 ,  C12N9/90 ,  C12P7/40 ,  C12N15/70 ,  C12P7/42 ,  C12P7/46 ,  C12P11/00 ,  G06F19/12

CPC classification number: C12N9/93 ,  C12N9/0006 ,  C12N9/0008 ,  C12N9/1018 ,  C12N9/1205 ,  C12N9/13 ,  C12N9/18 ,  C12N9/88 ,  C12N9/90 ,  C12N15/70 ,  C12N15/8245 ,  C12N15/8247 ,  C12N15/8269 ,  C12P7/40 ,  C12P7/42 ,  C12P7/46 ,  C12P11/00 ,  C12Y101/01059 ,  C12Y102/01018 ,  C12Y201/03001 ,  C12Y208/03001 ,  C12Y401/01031 ,  C12Y402/01017 ,  C12Y402/01054 ,  C12Y604/01001 ,  C12Y604/01002 ,  G16B5/00 ,  Y02P20/52

Abstract: A system for carbon fixation is provided. The system comprises enzymes which catalyze reactions of a carbon fixation pathway, wherein at least one of the reactions of the carbon fixation pathway is a carboxylation reaction, wherein products of the reactions of the carbon fixation pathway comprise oxaloacetate and malonyl-CoA, wherein an enzyme which performs the carboxylation reaction is selected from the group consisting of phophoenolpyruvate (PEP) carboxlase, pyruvate carboxylase and acetyl-CoA carboxylase and wherein an export product of the carbon fixation pathway is glyoxylate. Additional carbon fixation pathways are also provided and methods of generating same.

公开(公告)号：US20180253517A1

公开(公告)日：2018-09-06

申请号：US15969904

申请日：2018-05-03

Applicant: Yeda Research and Development Co. Ltd.

Inventor： Tali KIMCHI ,  Aharon WEISSBROD ,  Genadiy VASSERMAN

IPC: G06F17/50 ,  A01K1/03 ,  A01K29/00 ,  G01S3/14 ,  G01S3/786 ,  G06K9/62

CPC classification number: G06F17/5009 ,  A01K1/031 ,  A01K29/005 ,  G01S3/14 ,  G01S3/7864 ,  G06K9/6282

Abstract: A method of identifying and classifying social complex behaviors among a group of model organisms, comprising implanting at least one RFID transponder in each model organism in said group of model organisms; enclosing said group of model organisms in a monitored space divided into RFID monitored segments; RFID tracking a position of each model organism by reading said at least one RFID transponder in each model organism over a period of time; capturing a sequence of images of each model organism over said period of time; and calculating at least one spatiotemporal model of each model organism based on time synchronization of said RFID tracked position of said model organism with said sequence of images.

公开(公告)号：US10069094B2

公开(公告)日：2018-09-04

申请号：US15034186

申请日：2014-11-06

Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.

Inventor： Shahal Ilani ,  Sharon Pecker ,  Avishai Benyamini ,  Jonah Waissman ,  Assaf Hamo ,  Maayan Honig

IPC: H01L51/05 ,  H01L29/06 ,  H01L21/66 ,  H01L51/00 ,  H01L29/10 ,  H01L29/66 ,  H01L29/772 ,  H01L51/10 ,  C01B32/16

Abstract: A method for use in construction of an electronic device and a transistor structure are presented. The method comprising: providing one or more nanotubes grown on a surface of a first substrate; providing a desired electrode arrangement fabricated on a surface of a second substrate. The electrode arrangement comprises at least two elevated source and drain electrodes and one or more gate electrodes located in between said elevated source and drain electrodes. The method also comprises bringing the electrode arrangement on the second substrate to close proximity with the first substrate such that surfaces of the first and second substrates face each other; scanning said first substrate with said electrode arrangement and determining contact of electrodes of the electrode arrangement with a nanotube located on the first substrate; and detaching said nanotube from the first substrate to provide a transistor structure comprising an isolated nanotube between the source and drain electrodes.

公开(公告)号：US20180214827A1

公开(公告)日：2018-08-02

申请号：US15742541

申请日：2016-07-07

Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.

Inventor： Boris RYBTCHINSKI ,  Erez COHEN ,  Haim WEISSMAN

IPC: B01D71/64 ,  B01D71/36 ,  B01D71/66 ,  C08G73/10 ,  C08L79/08 ,  B01D69/12

CPC classification number: B01D71/64 ,  B01D65/02 ,  B01D69/12 ,  B01D71/36 ,  B01D71/66 ,  B01D2313/24 ,  B01D2321/168 ,  B01D2323/00 ,  B01D2325/00 ,  C07F1/12 ,  C07F3/08 ,  C08G73/10 ,  C08L79/08

Abstract: This invention is directed to filtration system, filtration apparatus and methods of use thereof, wherein the filtration system comprises a solid support, perylene diimide based membrane layer and a polymer, specifically a Nafion polymer. The system and apparatus of this invention enables filtration of solutes such as: dyes, salts, heavy metal ions, pharmaceuticals and small organic molecules.

公开(公告)号：US10030224B2

公开(公告)日：2018-07-24

申请号：US14929363

申请日：2015-11-01

Applicant: Ariel-University Research and Development Company Ltd. ,  Yeda Research and Development Co. Ltd. ,  Indian Institute of Technology Bombay

Inventor： Mordechai Sheves ,  Irishi N. N. Namboothiri ,  Guy Patchornik

IPC: C12N1/00 ,  C07K14/215

Abstract: A method of precipitating cell membrane fragments from a cell lysate is disclosed. The method comprises contacting the cell lysate with a hydrophobic chelator and a metal ion under conditions that allow precipitation of the cell membrane fragments. Kits for precipitating cell membrane fragments are also disclosed.

公开(公告)号：US20180161481A1

公开(公告)日：2018-06-14

申请号：US15890504

申请日：2018-02-07

Applicant: Yeda Research and Development Co. Ltd.

Inventor： Jacob KLEIN ,  Ronit GOLDBERG ,  Noa IUSTER ,  Raya SORKIN

IPC: A61L27/52 ,  C08F2/44 ,  A61K9/00 ,  A61L27/34 ,  A61L27/44 ,  C08F2/10 ,  C09D133/06

CPC classification number: A61L27/52 ,  A61K9/0019 ,  A61K9/0024 ,  A61L27/34 ,  A61L27/44 ,  A61L2300/626 ,  A61L2400/10 ,  A61L2430/06 ,  A61L2430/10 ,  A61L2430/24 ,  A61L2430/38 ,  C08F2/10 ,  C08F2/44 ,  C09D133/066

Abstract: Hydrogels and composite material containing hydrogels and liposomes dispersed therein, which exhibit a reduced friction coefficient compared to neat hydrogels or composites containing hydrogels, processes for preparing the same, and methods for using the same are disclosed.

公开(公告)号：US09998198B2

公开(公告)日：2018-06-12

申请号：US15346747

申请日：2016-11-09

Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.

Inventor： Avishay Gal-Yam ,  Barak Zackay ,  Eran Ofek

IPC: H04B1/00 ,  H04B7/08 ,  H04B17/20

CPC classification number: H04B7/0851 ,  H04B17/20 ,  H04B17/318 ,  H04B17/3912

Abstract: A method for detecting a dispersed pulse in a received signal that has been dispersed by a dispersive medium includes obtaining an input array of cells, each indicating an intensity of a frequency component of the signal at a representative time. A fast dispersion measure transform (FDMT) is applied to concurrently sum the cells of the input array that lie along different dispersion curves, each curve defined by a known non-linear functional form and being uniquely characterized by a time coordinate and by a value of the dispersion measure. Application of FDMT includes initially generating a plurality of sub-arrays, each representing a frequency sub-band and iteratively combining pairs of adjacent sub-arrays in accordance with an addition rule until all of the initially generated plurality of sub-arrays are combined into an output array of the sums, in which a cell of the output array that is indicative of a transmitted pulse is identified.

公开(公告)号：US09982051B2

公开(公告)日：2018-05-29

申请号：US15821678

申请日：2017-11-22

Applicant: Yeda Research and Development Co. Ltd.

Inventor： Michal Eisenbach-Schwartz ,  Kuti Baruch ,  Neta Rosenzweig

IPC: C07K16/28 ,  A61K39/395 ,  A61K31/7068 ,  A61K38/00 ,  A61K38/18 ,  A61K38/16 ,  A61K38/02 ,  A61K45/06 ,  A61K31/4155 ,  A61K38/14 ,  A61K38/20 ,  A61K33/36 ,  A61K31/404 ,  A61K39/00

CPC classification number: C07K16/2803 ,  A61K31/404 ,  A61K31/4155 ,  A61K31/7068 ,  A61K33/36 ,  A61K38/00 ,  A61K38/005 ,  A61K38/02 ,  A61K38/14 ,  A61K38/168 ,  A61K38/18 ,  A61K38/208 ,  A61K39/395 ,  A61K39/39541 ,  A61K39/3955 ,  A61K45/06 ,  A61K2039/505 ,  A61K2039/507 ,  A61K2039/545 ,  A61K2039/57 ,  A61K2039/572 ,  A61K2121/00 ,  C07K16/2818 ,  C07K16/2827 ,  C07K2317/21 ,  C07K2317/24 ,  C07K2317/75 ,  C07K2317/76 ,  A61K2300/00

Abstract: A pharmaceutical composition comprising an active agent that causes reduction of the level of systemic immunosuppression in an individual for use in treating a disease, disorder, condition or injury of the CNS that does not include the autoimmune neuroinflammatory disease, relapsing-remitting multiple sclerosis (RRMS), is provided. The pharmaceutical composition is for administration by a dosage regimen comprising at least two courses of therapy, each course of therapy comprising in sequence a treatment session followed by an interval session of non-treatment.

公开(公告)号：US09982050B2

公开(公告)日：2018-05-29

申请号：US15821672

申请日：2017-11-22

Applicant: Yeda Research and Development Co. Ltd.

Inventor： Michal Eisenbach-Schwartz ,  Kuti Baruch ,  Neta Rosenzweig

IPC: C07K16/28 ,  A61K39/395 ,  A61K38/16 ,  A61K31/7068 ,  A61K45/06 ,  A61K38/18 ,  A61K38/14 ,  A61K38/00 ,  A61K38/20 ,  A61K33/36 ,  A61K31/404 ,  A61K31/4155 ,  A61K39/00

CPC classification number: C07K16/2803 ,  A61K31/404 ,  A61K31/4155 ,  A61K31/7068 ,  A61K33/36 ,  A61K38/00 ,  A61K38/005 ,  A61K38/02 ,  A61K38/14 ,  A61K38/168 ,  A61K38/18 ,  A61K38/208 ,  A61K39/395 ,  A61K39/39541 ,  A61K39/3955 ,  A61K45/06 ,  A61K2039/505 ,  A61K2039/507 ,  A61K2039/545 ,  A61K2039/57 ,  A61K2039/572 ,  A61K2121/00 ,  C07K16/2818 ,  C07K16/2827 ,  C07K2317/21 ,  C07K2317/24 ,  C07K2317/75 ,  C07K2317/76 ,  A61K2300/00

Abstract: A pharmaceutical composition comprising an active agent that causes reduction of the level of systemic immunosuppression in an individual for use in treating a disease, disorder, condition or injury of the CNS that does not include the autoimmune neuroinflammatory disease, relapsing-remitting multiple sclerosis (RRMS), is provided. The pharmaceutical composition is for administration by a dosage regimen comprising at least two courses of therapy, each course of therapy comprising in sequence a treatment session followed by an interval session.

公开(公告)号：US09982048B2

公开(公告)日：2018-05-29

申请号：US15821595

申请日：2017-11-22

Applicant: Yeda Research and Development Co. Ltd.

Inventor： Michal Eisenbach-Schwartz ,  Kuti Baruch ,  Neta Rosenzweig

IPC: C07K16/28 ,  A61K39/395 ,  A61K38/16 ,  A61K31/7068 ,  A61K45/06 ,  A61K38/18 ,  A61K38/14 ,  A61K38/00 ,  A61K38/20 ,  A61K33/36 ,  A61K31/404 ,  A61K31/4155 ,  A61K39/00

CPC classification number: C07K16/2803 ,  A61K31/404 ,  A61K31/4155 ,  A61K31/7068 ,  A61K33/36 ,  A61K38/00 ,  A61K38/005 ,  A61K38/02 ,  A61K38/14 ,  A61K38/168 ,  A61K38/18 ,  A61K38/208 ,  A61K39/395 ,  A61K39/39541 ,  A61K39/3955 ,  A61K45/06 ,  A61K2039/505 ,  A61K2039/507 ,  A61K2039/545 ,  A61K2039/57 ,  A61K2039/572 ,  A61K2121/00 ,  C07K16/2818 ,  C07K16/2827 ,  C07K2317/21 ,  C07K2317/24 ,  C07K2317/75 ,  C07K2317/76 ,  A61K2300/00

Abstract: A pharmaceutical composition comprising an active agent that causes reduction of the level of systemic immunosuppression in an individual for use in treating a disease, disorder, condition or injury of the CNS that does not include the autoimmune neuroinflammatory disease, relapsing-remitting multiple sclerosis (RRMS), is provided. The pharmaceutical composition is for administration by a dosage regimen comprising at least two courses of therapy, each course of therapy comprising in sequence a treatment session followed by an interval session.