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    MODULAR AUTOMATED CHROMATOGRAPHY SYSTEM
    111.
    发明申请
    MODULAR AUTOMATED CHROMATOGRAPHY SYSTEM 审中-公开

    公开(公告)号：US20200041468A1

    公开(公告)日：2020-02-06

    申请号：US16595766

    申请日：2019-10-08

    Applicant: Bio-Rad Laboratories, Inc.

    Inventor： Robert IOVANNI ,  Alec GORDON ,  Bob AVARBOCK ,  Wayne BLAND ,  Glenn PRICE ,  Ken BAKER ,  Farah MAVANDADI ,  Christof SCHULTZ

    IPC: G01N30/38 ,  G01N30/46 ,  B01D15/18 ,  G01N30/88 ,  G05D7/06 ,  G05B15/02 ,  B01D15/10

    Abstract: Valves, pumps, detectors, sample loops, fraction collectors and the like are individually incorporated into modules that are mountable at individual mounting sites on a base unit which also supports one or more chromatography columns. Each module includes fluid connections to other modules and a microcontroller joining the module to a computed and monitor through an electronic connector at each mounting site. The fluid connections between the modules and the column(s) are removed from the electronic connections and accessible to the user. A software platform may recognize the modules and their locations, coordinate fluid connections between the modules, and provide a variety of control, monitoring, data generating and data processing functions to generate chromatographic data. The software platform may also provide graphical tools for designing chromatographic methods from a library of phases.

    Emulsion chemistry for encapsulated droplets
    117.
    发明授权
    Emulsion chemistry for encapsulated droplets 有权

    公开(公告)号：US10378048B2

    公开(公告)日：2019-08-13

    申请号：US15452582

    申请日：2017-03-07

    Applicant: Bio-Rad Laboratories, Inc.

    Inventor： Amy L. Hiddessen ,  Benjamin J. Hindson

    IPC: C12Q1/68 ,  C12Q1/6848 ,  C12Q1/6844 ,  C12Q1/6816 ,  C12Q1/686

    Abstract: System, including methods, apparatus, compositions, and kits, for making and using a stabilized emulsion. A method of generating a stabilized emulsion is provided. In the method, an aqueous phase may be provided. The aqueous phase may include an effective concentration of one or more skin-forming proteins. An emulsion may be formed. The emulsion may include droplets of a dispersed phase disposed in a continuous phase, with the aqueous phase being the continuous phase or the dispersed phase. The emulsion may be heated to create an interfacial skin between each droplet and the continuous phase, to transform the droplets into capsules.

    Fusion polymerases
    119.
    发明授权
    Fusion polymerases 有权

    公开(公告)号：US10351831B2

    公开(公告)日：2019-07-16

    申请号：US15801114

    申请日：2017-11-01

    Applicant: Bio-Rad Laboratories, Inc.

    Inventor： Yan Wang ,  Man Cheng

    IPC: C12N9/12 ,  C12Q1/686 ,  C12N9/22

    Abstract: Fusion polypeptides having a heterologous 5′-3′ exonuclease domain linked to a polymerase that does not naturally have 5′-3′ exonuclease activity, as well as methods of their use are provided. Other aspects are also disclosed.

    Immunoblotting systems and methods
    120.
    发明授权
    Immunoblotting systems and methods 有权

    公开(公告)号：US10330675B2

    公开(公告)日：2019-06-25

    申请号：US15003536

    申请日：2016-01-21

    Applicant: Bio-Rad Laboratories, Inc.

    Inventor： Ning Liu

    IPC: G01N33/543

    Abstract: Immunoblotting systems and method are provided. In one embodiment, the method may be achieved by applying an antibody solution to a surface of a membrane having an optically detectable protein and a target protein transferred thereon, wherein the application of the antibody solution is guided by a signal emitted from the optically detectable protein; and detecting the target protein. Systems and other methods are also described and illustrated.

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