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    Cardiac valve prosthesis
    123.
    发明授权
    Cardiac valve prosthesis 有权
    心脏瓣膜假体

    公开(公告)号：US09486313B2

    公开(公告)日：2016-11-08

    申请号：US14548013

    申请日：2014-11-19

    Applicant: Sorin Group Italia S.r.l.

    Inventor： Carla Stacchino ,  Giovanni Bergamasco ,  Gaetano Burriesci ,  Giovanni Righini

    IPC: A61F2/24 ,  A61F2/848

    CPC classification number: A61F2/2418 ,  A61F2/2436 ,  A61F2/2469 ,  A61F2/848 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2220/0075 ,  A61F2230/0054 ,  A61F2250/001 ,  Y10T29/49833

    Abstract: A method of repairing a native cardiac valve such as the aortic valve includes positioning a cardiac valve prosthesis at an implantation site proximate the native cardiac valve to be repaired. The cardiac valve prosthesis includes an armature and a plurality of prosthetic valve leaflets, the armature including first and second annular elements, a plurality of anchor members extending between the first and second annular elements, and a plurality of valve support members extending from at least one of the first and second annular elements, the plurality of prosthetic valve leaflets being coupled to and supported by the valve support members. The method further includes radially expanding the cardiac valve prosthesis such that each of the anchor members arches radially outward from the first annular element to the second annular element and engages a wall of a respective one of a plurality of native Valsalva sinuses located distal to the native cardiac valve so as to enable anchorage of the cardiac valve prosthesis at the implantation site.

    Abstract translation: 修复诸如主动脉瓣的天然心脏瓣膜的方法包括将心脏瓣膜假体定位在靠近待修复的天然心脏瓣膜的植入部位。 所述心脏瓣膜假体包括电枢和多个假体瓣膜小叶，所述电枢包括第一和第二环形元件，在所述第一和第二环形元件之间延伸的多个锚定构件以及从至少一个 的第一和第二环形元件，所述多个人造瓣叶单元联接到阀支撑构件并由阀支撑构件支撑。 该方法还包括径向扩张心脏瓣膜假体，使得每个锚固构件从第一环形元件径向向外拱形到第二环形元件并且接合位于远离本地的多个天然瓦萨尔瓦鼻窦中的相应一个的壁 心脏瓣膜，以便能够在植入部位处锚定心脏瓣膜假体。

    METHOD FOR PREPARING BIOLOGICAL TISSUES FOR USE IN BIOLOGICAL PROSTHESES
    124.
    发明申请
    METHOD FOR PREPARING BIOLOGICAL TISSUES FOR USE IN BIOLOGICAL PROSTHESES 有权
    制备生物组织用于生物学前景的方法

    公开(公告)号：US20160095957A1

    公开(公告)日：2016-04-07

    申请号：US14966675

    申请日：2015-12-11

    Applicant: Sorin Group Italia S.r.l.

    Inventor： Marina Strasly ,  Giovanni Rolando

    IPC: A61L27/36

    CPC classification number: A61L27/3687 ,  A61K35/12 ,  A61L27/3683

    Abstract: A method of treating a biological tissue for biological prostheses includes steps of fixation of the biological tissue via a fixing solution including glutaraldehyde and detoxification of the fixed biological tissue via treatment with a detoxifying solution. The detoxification step includes one or both of eliminating phospholipids via treatment with an elimination solution and a treatment with a detoxifying solution. The elimination solution includes 1,2-octanediol and ethanol. The detoxifying solution includes taurine or homocysteic acid.

    Abstract translation: 用于生物假体处理生物组织的方法包括通过包含戊二醛的固定溶液固定生物组织并通过用解毒溶液处理来固定固定的生物组织的步骤。 解毒步骤包括通过用消除溶液处理和用解毒溶液处理来消除磷脂的一种或两种。 消除溶液包括1,2-辛二醇和乙醇。 解毒溶液包括牛磺酸或高半胱氨酸。

    Valve prosthesis and kit
    125.
    发明授权
    Valve prosthesis and kit 有权
    阀门假体和试剂盒

    公开(公告)号：US09186249B2

    公开(公告)日：2015-11-17

    申请号：US13962789

    申请日：2013-08-08

    Applicant: Sorin Group Italia S.r.l.

    Inventor： Giovanni Rolando ,  Paolo Gaschino ,  Laura Ghione ,  Andrea Marchisio ,  Monica Achiluzzi

    IPC: A61F2/24

    CPC classification number: A61F2/2412 ,  A61F2/2418 ,  A61F2/2436 ,  A61F2220/0075

    Abstract: Described is a valve prosthesis comprising: an annular structure, and a plurality of valve leaflets, and a plurality of anchoring members attached around the annular structure, the anchoring members including: a web portion coupled to the annular structure and extending axially thereto, and two end portions at axially opposed sides of the web portion, the end portions having: an insertion condition for insertion of the prosthesis, wherein the end portions are aligned to the web portion and extend axially with respect to the annular structure; and an anchoring condition for anchoring the prosthesis, wherein the end portions extend at an angle to the web portion radially outwardly of the annular structure to provide anchoring of the prosthesis proximally and distally, respectively, of the annulus, and wherein one end portion forms an obtuse angle with the web portion.

    Abstract translation: 描述了一种阀门假体，其包括：环形结构，以及多个瓣叶，以及围绕环形结构附接的多个锚固构件，所述锚定构件包括：腹板部分，其联接到所述环形结构并且轴向延伸， 所述端部具有用于插入所述假体的插入状态，其中所述端部与所述腹板部分对准并且相对于所述环形结构轴向延伸; 以及用于锚定假体的锚固条件，其中端部部分以与环形结构的径向外侧的腹板部分成一定角度延伸，以分别使瓣膜近端和远端锚固假体，并且其中一个端部形成 与网部分呈钝角。

    MONITORING SYSTEM FOR CARDIAC SURGICAL OPERATIONS WITH CARDIOPULMONARY BYPASS
    126.
    发明申请
    MONITORING SYSTEM FOR CARDIAC SURGICAL OPERATIONS WITH CARDIOPULMONARY BYPASS 审中-公开
    用心脏旁路手术进行心脏手术的监测系统

    公开(公告)号：US20150272487A1

    公开(公告)日：2015-10-01

    申请号：US14738805

    申请日：2015-06-12

    Applicant: Sorin Group Italia S.r.l.

    Inventor： Marco Ranucci

    IPC: A61B5/145 ,  A61B5/00 ,  A61M1/14 ,  A61B5/01

    CPC classification number: A61B5/4836 ,  A61B5/01 ,  A61B5/0205 ,  A61B5/0816 ,  A61B5/082 ,  A61B5/14535 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/4866 ,  A61B5/6866 ,  A61B5/7278 ,  A61B5/742 ,  A61B5/746 ,  A61B2505/05 ,  A61M1/14 ,  A61M1/32 ,  A61M1/3621 ,  A61M1/3666 ,  A61M2230/20 ,  A61M2230/205 ,  A61M2230/207 ,  G06F19/00 ,  G16H40/63

    Abstract: A monitoring system for cardiac operations with cardiopulmonary bypass comprising: a processor operatively connected to a heart-lung machine; a pump flow detecting device connected to a pump of the heart-lung machine to continuously measure the pump flow value and send it to the processor; a hematocrit reading device to continuously measure the blood hematocrit value and to send it to the processor; a data input device to allow the operator to manually input data regarding the arterial oxygen saturation and the arterial oxygen tension; computing means integrated in the processor to compute the oxygen delivery value on the basis of the measured pump flow, the measured hematocrit value, the preset value of arterial oxygen saturation, and the preset value of arterial oxygen tension; and a display connected to the processor to display in real-time the computed oxygen delivery value.

    Abstract translation: 一种用于心肺分流术的心脏手术的监测系统，包括：处理器，可操作地连接到心肺机器; 泵流量检测装置连接到心肺机的泵，以连续测量泵流量值并将其发送到处理器; 血细胞比容读取装置，用于连续测量血液血细胞比容值并将其发送到处理器; 数据输入装置，允许操作者手动输入关于动脉氧饱和度和动脉氧气张力的数据; 计算装置集成在处理器中，以测量的泵流量，测量的血细胞比容值，动脉血氧饱和度的预设值和动脉氧气张力的预设值为基础计算氧气输送值; 以及连接到处理器的显示器，以实时显示计算出的氧气输送值。

    CARDIAC VALVE PROSTHESIS
    127.
    发明申请
    CARDIAC VALVE PROSTHESIS 有权

    公开(公告)号：US20150148895A1

    公开(公告)日：2015-05-28

    申请号：US14548013

    申请日：2014-11-19

    Applicant: Sorin Group Italia S.r.l.

    Inventor： Carla Stacchino ,  Giovanni Bergamasco ,  Gaetano Burriesci ,  Giovanni Righini

    IPC: A61F2/24

    CPC classification number: A61F2/2418 ,  A61F2/2436 ,  A61F2/2469 ,  A61F2/848 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2220/0075 ,  A61F2230/0054 ,  A61F2250/001 ,  Y10T29/49833

    Abstract: A method of repairing a native cardiac valve such as the aortic valve includes positioning a cardiac valve prosthesis at an implantation site proximate the native cardiac valve to be repaired. The cardiac valve prosthesis includes an armature and a plurality of prosthetic valve leaflets, the armature including first and second annular elements, a plurality of anchor members extending between the first and second annular elements, and a plurality of valve support members extending from at least one of the first and second annular elements, the plurality of prosthetic valve leaflets being coupled to and supported by the valve support members. The method further includes radially expanding the cardiac valve prosthesis such that each of the anchor members arches radially outward from the first annular element to the second annular element and engages a wall of a respective one of a plurality of native Valsalva sinuses located distal to the native cardiac valve so as to enable anchorage of the cardiac valve prosthesis at the implantation site.

    Abstract translation: 修复诸如主动脉瓣的天然心脏瓣膜的方法包括将心脏瓣膜假体定位在靠近待修复的天然心脏瓣膜的植入部位。 所述心脏瓣膜假体包括电枢和多个假体瓣膜小叶，所述电枢包括第一和第二环形元件，在所述第一和第二环形元件之间延伸的多个锚定构件以及从至少一个 的第一和第二环形元件，所述多个人造瓣叶单元联接到阀支撑构件并由阀支撑构件支撑。 该方法还包括径向扩张心脏瓣膜假体，使得每个锚固构件从第一环形元件径向向外拱形到第二环形元件并且接合位于远离本地的多个天然瓦萨尔瓦鼻窦中的相应一个的壁 心脏瓣膜，以便能够在植入部位处锚定心脏瓣膜假体。

    BI-DIRECTIONAL PERFUSION CANNULA
    128.
    发明申请
    BI-DIRECTIONAL PERFUSION CANNULA 审中-公开
    双向灌注肛门

    公开(公告)号：US20140330250A1

    公开(公告)日：2014-11-06

    申请号：US14335931

    申请日：2014-07-20

    Applicant: Sorin Group Italia S.r.l.

    Inventor： Randall Moshinsky ,  James McMillan ,  Elli Tutungi

    IPC: A61M1/36

    CPC classification number: A61M1/3659 ,  A61B5/02141 ,  A61B5/0215 ,  A61B5/6847 ,  A61M25/0041 ,  A61M25/0043 ,  A61M25/007 ,  A61M2025/006 ,  F04C2270/041

    Abstract: A bi-directional perfusion cannula is provided that includes an elongate tube for insertion into an artery. The elongate tube has a first aperture at a distal end of the tube which is forward during insertion and configured so that blood can flow into the artery in the direction of insertion, an elbow formed in the elongate tube, and a second aperture formed in or slightly rearward of the elbow and configured for supplying blood into the artery in a second direction which is generally opposite to the insertion direction.

    Abstract translation: 提供了一种双向灌注套管，其包括用于插入动脉的细长管。 细长管具有在管的远端处的第一孔，其在插入期间向前并且构造成使得血液可以在插入方向上流动到动脉中，形成在细长管中的弯头，以及形成在其中的第二孔， 在肘部的稍后方，构成为在大致与插入方向相反的第二方向向动脉供血。

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