公开(公告)号：US09459201B2

公开(公告)日：2016-10-04

申请号：US14869550

申请日：2015-09-29

Applicant: Zyomed Corp.

Inventor： Sandeep Gulati ,  Timothy L. Ruchti ,  William V. Antwerp ,  John L. Smith

IPC: G01J5/02 ,  G01N21/3577 ,  A61B5/024 ,  G01N21/359 ,  G01N21/47 ,  G01N21/49 ,  G01N33/49 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1455 ,  A61B5/1495

CPC classification number: A61B5/14532 ,  A61B5/0075 ,  A61B5/024 ,  A61B5/02416 ,  A61B5/02433 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/1495 ,  A61B5/7203 ,  A61B5/7235 ,  A61B5/7253 ,  A61B5/7264 ,  A61B5/7267 ,  A61B2560/0223 ,  G01N21/3577 ,  G01N21/359 ,  G01N21/4795 ,  G01N21/49 ,  G01N33/4833 ,  G01N33/49 ,  G01N2201/0612 ,  G01N2201/062 ,  G01N2201/067 ,  G01N2201/12 ,  G01N2201/129

Abstract: In a noninvasive system for detection/measurement of glucose and other analytes in a medium such as tissue, spectra from the medium are deconstructed into features. Conditioned features, which contain frequency components specific to glucose or the other analytes, are derived from one or more features by modulating a carrier kernel with the feature. The conditioned features are computationally collided with one or more Zyotons that are co-dependent with the conditioned features. One or more collisions amplify a property of the analyte e.g., energy absorbed by glucose in tissue from radiation directed to the skin. A gradient of several values of the amplified property, each value corresponding to a particular radiation pattern according to a spectroscopic tomographic sequence, is used to select a suitable projector curve, with which a representative amplified value is projected to an accurate estimate of the concentration of glucose or the other analytes, without needing personalized calibration.

公开(公告)号：US09453794B2

公开(公告)日：2016-09-27

申请号：US15081430

申请日：2016-03-25

Applicant: Zyomed Corp.

Inventor： Sandeep Gulati ,  Timothy L. Ruchti ,  William Van Antwerp ,  John L. Smith

IPC: G01J5/02 ,  G01N21/359 ,  G01N33/483 ,  A61B5/1455 ,  A61B5/145

CPC classification number: A61B5/14532 ,  A61B5/0075 ,  A61B5/024 ,  A61B5/02416 ,  A61B5/02433 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/1495 ,  A61B5/7203 ,  A61B5/7235 ,  A61B5/7253 ,  A61B5/7264 ,  A61B5/7267 ,  A61B2560/0223 ,  G01N21/3577 ,  G01N21/359 ,  G01N21/4795 ,  G01N21/49 ,  G01N33/4833 ,  G01N33/49 ,  G01N2201/0612 ,  G01N2201/062 ,  G01N2201/067 ,  G01N2201/12 ,  G01N2201/129

Abstract: In a noninvasive system for detection/measurement of glucose and other analytes in a medium such as tissue, illumination is directed to the medium and corresponding radiation from the medium is collected. Spectral energy changes associated with fragment(s)/feature(s) obtained from the collected radiation are determined using collision computing. Such spectral energy changes generally represent analyte concentration. The illumination is controlled to target a particular volume of the medium and/or such that the spectral energy changes become directionally monotonic with respect to analyte concentration. The illumination parameters include: intensity, wavelength, bandwidth, focal length, and/or duration of illumination, location and/or a size of an illuminated spot on the medium surface, depth at which the illumination can reach below the medium surface, spacing between the illuminated spot and a spot on the medium surface from which radiation is collected, and angle of the illumination relative to the medium surface.

Abstract translation: 在用于在诸如组织的培养基中检测/测量葡萄糖和其它分析物的非侵入性系统中，照射被引导到介质并收集来自培养基的相应辐射。 使用碰撞计算确定与从收集的辐射获得的片段/特征相关联的光谱能量变化。 这种光谱能量变化通常表示分析物浓度。 控制照明以靶向介质的特定体积和/或使得光谱能量变化相对于分析物浓度变得方向性单调。 照明参数包括：照明的强度，波长，带宽，焦距和/或持续时间，介质表面上的照明光斑的位置和/或尺寸，照明可以到达介质表面下方的深度， 照明光斑和收集辐射的介质表面上的光点以及相对于介质表面的照明角度。

公开(公告)号：US09448179B2

公开(公告)日：2016-09-20

申请号：US14578666

申请日：2014-12-22

Applicant: HORIBA, Ltd.

Inventor： Yusuke Mizuno ,  Takuji Oida ,  Misato Arakawa

IPC: G01N7/00 ,  G01N21/00 ,  G01N27/00 ,  G01N31/00 ,  G01N33/00 ,  G01N17/00 ,  G01N21/76

CPC classification number: G01N21/766 ,  G01N33/0026 ,  G01N2201/129

Abstract: A gas analyzing apparatus includes a gas analyzing unit, a luminescence inducing component generating unit, and a measurement signal calculating unit. The gas analyzing unit receives a sample gas containing a component gas and/or a standard gas and the luminescence inducing gas. The gas analyzing unit is configured to output a detection signal based on an intensity of a reaction light generated by the interaction between the component gas and the luminescence inducing component. The luminescence inducing component generating unit generates the luminescence inducing gas by electric discharge generated repeatedly at specified intervals. The measurement signal calculating unit calculates a first measurement signal based on a first detection signal, based on the reaction light generated when the sample gas and the luminescence inducing gas are introduced, and a second detection signal, based on the reaction light generated when the standard gas and the luminescence inducing gas are introduced.

Abstract translation: 气体分析装置包括气体分析单元，发光感应组件生成单元和测量信号计算单元。 气体分析单元接收含有成分气体和/或标准气体和发光诱导气体的样品气体。 气体分析单元被配置为基于由组分气体和发光诱导组件之间的相互作用产生的反应光的强度来输出检测信号。 发光诱导分量产生单元通过以规定的间隔重复产生的放电产生发光诱导气体。 测量信号计算单元基于当引入样品气体和发光诱导气体时产生的反应光，基于第一检测信号计算第一测量信号，并且基于当标准 引入气体和发光诱导气体。

公开(公告)号：US09448164B2

公开(公告)日：2016-09-20

申请号：US14993819

申请日：2016-01-12

Applicant: Zyomed Corp.

Inventor： Sandeep Gulati ,  Timothy L. Ruchti ,  William Van Antwerp ,  John L. Smith

IPC: G01J5/02 ,  G01N21/3577 ,  A61B5/024 ,  G01N21/359 ,  G01N21/47 ,  G01N21/49 ,  G01N33/49 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1455 ,  A61B5/1495

CPC classification number: A61B5/14532 ,  A61B5/0075 ,  A61B5/024 ,  A61B5/02416 ,  A61B5/02433 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/1495 ,  A61B5/7203 ,  A61B5/7235 ,  A61B5/7253 ,  A61B5/7264 ,  A61B5/7267 ,  A61B2560/0223 ,  G01N21/3577 ,  G01N21/359 ,  G01N21/4795 ,  G01N21/49 ,  G01N33/4833 ,  G01N33/49 ,  G01N2201/0612 ,  G01N2201/062 ,  G01N2201/067 ,  G01N2201/12 ,  G01N2201/129

Abstract: In a noninvasive system for detection/measurement of glucose and other analytes in a medium such as tissue, spectra from the medium are deconstructed into features. Conditioned features, which contain frequency components specific to glucose or the other analytes, are derived from one or more features by modulating a carrier kernel with the feature. The conditioned features are computationally collided with one or more Zyotons that are co-dependent with the conditioned features. One or more collisions amplify a property of the analyte e.g., energy absorbed by glucose in tissue from radiation directed to the skin. A gradient of several values of the amplified property, each value corresponding to a particular radiation pattern according to a spectroscopic tomographic sequence, is used to select a suitable projector curve, with which a representative amplified value is projected to an accurate estimate of the concentration of glucose or the other analytes, without needing personalized calibration.

Abstract translation: 在用于在诸如组织的培养基中检测/测量葡萄糖和其它分析物的非侵入性系统中，来自培养基的光谱被解构为特征。 包含特定于葡萄糖或其他分析物的频率分量的条件特征通过调制具有该特征的载体核心从一个或多个特征导出。 条件特征与一个或多个与条件特征相关的Zyotons计算相撞。 一个或多个碰撞放大分析物的性质，例如组织中由葡萄糖吸收的能量，辐射被引导到皮肤。 使用放大性能的几个值的梯度，每个值对应于根据光谱断层扫描序列的特定辐射图，其值被选择合适的投影仪曲线，其中代表性的放大值被预测为准确地估计浓度 葡萄糖或其他分析物，不需要个性化校准。

公开(公告)号：US20160258877A1

公开(公告)日：2016-09-08

申请号：US15060865

申请日：2016-03-04

Applicant: The Petroleum Institute

Inventor： Esra Al Hosani ,  Mahmoud Meribout

IPC: G01N21/85 ,  G01N21/94 ,  G01N21/65

CPC classification number: G01N21/85 ,  G01N21/359 ,  G01N21/532 ,  G01N21/65 ,  G01N21/94 ,  G01N2021/8578 ,  G01N2201/129

Abstract: A method and system for determination of contaminants, such as black powder, in a flowing fluid, such as natural gas, is disclosed. The method comprises transmitting a plurality of light beams over a spectrum of wavelengths through the flowing fluid in a main pipeline and receiving a plurality of measurements relating to transmitted and scattered light beams over the spectrum of wavelengths. The measurements relate to at least one of absorption, reflection or refraction. The received plurality of measurements are compared with a plurality of stored patterns and a result indicative of the determination of the contaminants is output.

Abstract translation: 公开了一种用于确定诸如天然气的流动流体中诸如黑色粉末之类的污染物的方法和系统。 该方法包括通过主管线中的流动流体在波长波长上传输多个光束，并且接收与波长频谱上的透射和散射光束有关的多个测量。 测量涉及吸收，反射或折射中的至少一种。 将接收到的多个测量值与多个存储的模式进行比较，并且输出指示污染物的确定的结果。

公开(公告)号：US20160238520A1

公开(公告)日：2016-08-18

申请号：US15029163

申请日：2014-10-17

Applicant: BENTLEY INSTRUMENTS

Inventor： Pierre BROUTIN

IPC: G01N21/27 ,  G01N33/487 ,  G01N21/3577

CPC classification number: G01N21/274 ,  G01N21/3577 ,  G01N33/04 ,  G01N33/487 ,  G01N2021/3595 ,  G01N2201/127 ,  G01N2201/129 ,  G01N2800/044

Abstract: Method for calibrating an infrared spectroscopy apparatus to produce spectra to determine the concentration of a component C1 in one fluid F1 of an animal, includes: a) obtaining samples of fluid F1 and of a different fluid from each animal belonging to a group of representative animals, fluid F2 containing detectable amounts of at least one component C2 which is directly or indirectly related to a metabolic pathway of component C1; b) measuring the concentration of component C1 in the samples of fluid F1; c) producing the complete IR absorption spectrum of the samples of fluid F2; d) identifying in the absorption spectra of fluid F2 samples the spectral ranges that correlate with the concentration of component C1 in fluid F1 samples; and e) calculating, on the basis of at least one of the correlating spectral ranges, a predictive mathematical model of the concentration of component C1 in fluid F1.

Abstract translation: 用于校准红外光谱仪器以产生光谱以确定动物的一个流体F1中的组分C1的浓度的方法包括：a）获得来自属于一组代表动物的每种动物的流体F1和不同流体的样品 ，含有可检测量的至少一种与组分C1的代谢途径直接或间接相关的组分C2的流体F2; b）测量流体F1样品中组分C1的浓度; c）产生流体F2样品的完全IR吸收光谱; d）在流体F2样品的吸收光谱中识别与流体F1样品中组分C1的浓度相关的光谱范围; 以及e）基于所述相关光谱范围中的至少一个计算流体F1中的组分C1的浓度的预测数学模型。

公开(公告)号：US20160146738A1

公开(公告)日：2016-05-26

申请号：US14948442

申请日：2015-11-23

Applicant: Ingrain, Inc.

Inventor： Joel Walls ,  Kathryn Elizabeth Washburn

IPC: G01N21/71 ,  G01N33/24

CPC classification number: G01N21/718 ,  G01N33/241 ,  G01N33/246 ,  G01N33/2823 ,  G01N2201/129

Abstract: A method for analysing fluid characteristics of a geological sample with laser-induced breakdown spectral measurements performed on the geological sample, spectral pre-processing performed as necessary, and subsequent analysis is applied to the collected data to determine at least one fluid parameter of the sample. The method can provide a more rapid and reliable method to estimate fluid properties of a geological sample. A system for performing the method also is provided.

Abstract translation: 一种用于分析地质样品的流体特性的方法，其中对地质样品进行激光诱发的击穿光谱测量，根据需要进行光谱预处理和随后的分析，并将其应用于收集的数据，以确定样品的至少一个流体参数 。 该方法可以提供更快速和可靠的方法来估计地质样品的流体性质。 还提供了一种用于执行该方法的系统。

公开(公告)号：US09339220B2

公开(公告)日：2016-05-17

申请号：US13862266

申请日：2013-04-12

Applicant: Cercacor Laboratories, Inc.

Inventor： Marcelo M. Lamego ,  Mohamed Diab ,  Walter M. Weber ,  Ammar Al-Ali ,  Joe Kiani

IPC: A61B5/1455 ,  A61B5/00 ,  G01N21/31 ,  A61B5/0205 ,  A61B5/1495 ,  A61B5/024 ,  G01N21/35 ,  G01N21/359

CPC classification number: A61B5/14552 ,  A61B5/0205 ,  A61B5/02416 ,  A61B5/14551 ,  A61B5/1495 ,  A61B5/6826 ,  A61B5/6838 ,  A61B5/72 ,  G01N21/314 ,  G01N21/35 ,  G01N21/359 ,  G01N2201/0627 ,  G01N2201/129

Abstract: A physiological monitor for determining blood oxygen saturation of a medical patient includes a sensor, a signal processor and a display. The sensor includes at least three light emitting diodes. Each light emitting diode is adapted to emit light of a different wavelength. The sensor also includes a detector, where the detector is adapted to receive light from the three light emitting diodes after being attenuated by tissue. The detector generates an output signal based at least in part upon the received light. The signal processor determines blood oxygen saturation based at least upon the output signal, and the display provides an indication of the blood oxygen saturation.

公开(公告)号：US20160123871A1

公开(公告)日：2016-05-05

申请号：US14893794

申请日：2014-05-28

Applicant: FLOORING TECHNOLOGIES LTD.

Inventor： Norbert Kalwa ,  Andre Denk

IPC: G01N21/3554 ,  G01N21/359 ,  G01N21/3563

CPC classification number: G01N21/3554 ,  E04F13/16 ,  E04F15/10 ,  G01N21/3563 ,  G01N21/359 ,  G01N2201/129

Abstract: A method for determining the moisture content of at least one resin layer provided on at least one wooden board as carrier board, wherein between the at least one resin layer and the carrier board an NIR reflecting layer is provided, including recording of at least one NIR spectrum of the at least one resin layer provided on the at least one carrier board using a NIR detector in a wavelength range between 500 nm an 2500 nm; determining the moisture content of the resin layer by comparing the NIR spectrum recorded for the resin layer to be measured with at least one NIR spectrum recorded for at least one reference sample with known moisture content by means of a multivariate data analysis, wherein the at least one NIR spectrum recorded was determined previously using the same NIR detector in a wavelength range between 500 nm and 2500 nm.

Abstract translation: 一种用于确定至少一个树脂层的水分含量的方法，所述至少一个树脂层设置在作为载体板的至少一个木板上，其中在所述至少一个树脂层和所述载体板之间设置有NIR反射层，包括记录至少一个NIR 使用在500nm至2500nm之间的波长范围内的NIR检测器在至少一个载体板上提供的至少一个树脂层的光谱; 通过将通过多变量数据分析比较记录的待测树脂层的NIR光谱与至少一个参考样品记录的至少一个参考样品与已知水分含量相比较来确定树脂层的水分含量，其中至少 使用相同的NIR检测器在500nm至2500nm之间的波长范围内先前测定了记录的一个NIR光谱。

公开(公告)号：US09329086B2

公开(公告)日：2016-05-03

申请号：US13905817

申请日：2013-05-30

Applicant: CHEMIMAGE TECHNOLOGIES LLC

Inventor： Patrick J. Treado ,  Ryan Priore

IPC: G01N21/00 ,  G01J3/51 ,  G01J3/457 ,  G01N21/25 ,  G01J3/02 ,  G01N21/33 ,  G01N21/359 ,  G01N21/65 ,  G01N21/71 ,  G01J3/12 ,  G01N21/64 ,  G01N21/35

CPC classification number: G01J3/51 ,  G01J3/0224 ,  G01J3/0272 ,  G01J3/457 ,  G01J2003/1213 ,  G01N21/255 ,  G01N21/33 ,  G01N21/35 ,  G01N21/359 ,  G01N21/65 ,  G01N21/718 ,  G01N2021/6471 ,  G01N2201/0221 ,  G01N2201/067 ,  G01N2201/129

Abstract: A portable system and method for analyzing biological tissue samples and detecting analytes associated with tissue oxygenation using a conformal filter. A conformal filter, which may comprise a tunable filter, is configured to filter interacted photons conforming to a spectral shape correlated with an analyte of interest. Conformal filter configurations may be selected by consulting a modified look-up table associated with an analyte. An iterative methodology may be used to calibrate a conformal design for an analyte of interest, refine a previous conformal filter design for an analyte of interest, and/or generate a new conformal filter design for an analyte of interest.

Abstract translation: 用于分析生物组织样品并使用保形过滤器检测与组织氧合相关的分析物的便携式系统和方法。 可以包括可调滤波器的保形滤波器被配置为滤波符合与感兴趣的分析物相关的光谱形状的相互作用的光子。 可以通过咨询与分析物相关联的经修改的查找表来选择保形过滤器配置。 可以使用迭代方法来校准感兴趣分析物的共形设计，改进目标分析物的先前共形过滤器设计，和/或为感兴趣的分析物生成新的保形过滤器设计。