公开(公告)号：US09619875B2

公开(公告)日：2017-04-11

申请号：US14694319

申请日：2015-04-23

Applicant: William Rooney ,  Xin Li

Inventor： William Rooney ,  Xin Li

IPC: G06K9/00 ,  G06T7/00 ,  A61K49/10

CPC classification number: G06T7/00 ,  A61B5/055 ,  A61B5/4064 ,  A61B2576/026 ,  A61K49/106 ,  G01R33/50 ,  G01R33/5601 ,  G01R33/5608 ,  G06T7/0016 ,  G06T2200/04 ,  G06T2207/10088 ,  G06T2207/10096 ,  G06T2207/30016 ,  G06T2207/30096 ,  G06T2207/30104

Abstract: Disclosed are methods and systems for calculating a contrast reagent (CR) extravasation rate constant and generating a contrast reagent leakage corrected relative cerebral blood volume (rCBV) image map of a brain region from dynamic susceptibility contrast (DSC) magnetic resonance imaging (MRI) time-course image data based on pharmacokinetic first principles. In one example approach, a computerized method may include performing a linearization transform of a DSC MRI time-course equation which accounts for an intravascular contribution and an extravasating component, and calculating CR leakage from a slope of a linear portion of the transformed data.

公开(公告)号：US09598551B2

公开(公告)日：2017-03-21

申请号：US14114140

申请日：2012-05-04

Applicant: Bo Liang ,  Bing Qin ,  Stefan Pastine ,  Xin Li

Inventor： Bo Liang ,  Bing Qin ,  Stefan Pastine ,  Xin Li

IPC: C08J11/16 ,  C08J11/26 ,  C08J5/04

CPC classification number: C08J11/16 ,  C08J5/04 ,  C08J11/26 ,  C08J2363/00 ,  Y02W30/705 ,  Y02W30/706 ,  Y10T442/3585

Abstract: The present invention relates to a reinforced composite and method for recycling the same. The reinforced composite comprises a reinforcement material in a cross-linked polymer matrix, wherein the cross-linked polymer comprises a cross-linking group derived from a curing agent represented by formula (I), Wherein R1 is hydrogen, alkyl, cycloalkyl, heterocycloalkyl, alkenyl, cycloalkenyl, aryl, heteroaryl, alkoxy alkyl or alkynyl; A is alkyl, alkenyl, alkenene, alkylene-hetero-alkylene, alkylene-heterocyclo-alkylene, alkylene, alkylene-oxy-alkylene, 1,4-alkyl substituted piperazine, carbonyl, thiocarbonyl; B is alkyl, alkenyl, alkenene, alkylene-hetero-alkylene, alkylene-heterocyclo-alkylene, alkylene, alkylene-oxy-alkylene, 1,4-alkyl substituted piperazine, carbonyl, thiocarbonyl; R2 is hydrogen, alkyl, aminoalkyl, alkyl-amino-alkyl, cycloalkyl, heterocycloalkyl, alkenyl, aryl, or heteroaryl; and R3 is hydrogen, alkyl, aminoalkyl, alkyl-amino-alkyl, cycloalkyl, heterocycloalkyl, alkenyl, aryl, or heteroaryl.

公开(公告)号：US20170039450A1

公开(公告)日：2017-02-09

申请号：US14440248

申请日：2014-04-30

Applicant: Shuchang ZHOU ,  Xin LI ,  Sheng LUO ,  Peng CHEN ,  Jian Li ,  Google Inc.

Inventor： Shuchang Zhou ,  Xin Li ,  Sheng Luo ,  Peng Chen ,  Jian Li

IPC: G06K9/62 ,  G06F17/30 ,  G06F3/0484 ,  H04N5/232 ,  G06K9/46

CPC classification number: G06K9/6215 ,  G06F3/04842 ,  G06F16/29 ,  G06F16/532 ,  G06F16/583 ,  G06K9/228 ,  G06K9/4671 ,  G06K9/623 ,  H04N5/23293

Abstract: Systems and methods for storefront recognition are provided. A surveyor or other user can access an application implemented on a computing device. A source image of a storefront of an entity can be captured by the surveyor using an image capture device (e.g. a digital camera). A feature matching process can be used to compare the source image against a plurality of candidate images of storefronts in the geographic area and return a list of the candidate images with the closest match. Each candidate image returned by the application can be annotated with a similarity score indicative of the similarity of the source image with the candidate image. The surveyor can use the similarity scores and the candidate images to determine whether the store has been previously investigated. The user can interact with the application to indicate whether the entity seeds to be investigated.

Abstract translation: 提供了用于店面识别的系统和方法。 测量员或其他用户可以访问在计算设备上实现的应用。 测量人员可以使用图像捕获设备（例如数码相机）捕获实体店面的源图像。 可以使用特征匹配处理来将源图像与地理区域中的店面的多个候选图像进行比较，并返回具有最接近匹配的候选图像的列表。 应用程序返回的每个候选图像可以用指示源图像与候选图像的相似度的相似性分数进行注释。 测量师可以使用相似度分数和候选图像来确定商店是否已经被调查过。 用户可以与应用程序进行交互，以指示实体是否要进行种子调查。

公开(公告)号：US09490111B2

公开(公告)日：2016-11-08

申请号：US13807526

申请日：2011-06-30

Applicant: Christopher Abell ,  Wilhelm T. S. Huck ,  Timothy Sharpe ,  Clive Smith ,  Todd Mize ,  Carol Robinson ,  Xin Li

Inventor： Christopher Abell ,  Wilhelm T. S. Huck ,  Timothy Sharpe ,  Clive Smith ,  Todd Mize ,  Carol Robinson ,  Xin Li

IPC: G01N24/00 ,  H01J49/00 ,  H01J49/16 ,  H01J49/26

CPC classification number: H01J49/0031 ,  H01J49/16 ,  H01J49/165 ,  H01J49/26

Abstract: Systems that employ microdroplets are used in embodiments for Microdroplet Electrospray Ionisation Mass Spectrometry (ESI MS). Thus, a method of detecting an analyte includes providing an oil composition comprising oil and an aqueous microdroplet comprising the analyte, the oil composition comprising a surfactant to stabilise the aqueous microdroplet in the oil composition; and performing ionisation mass spectrometry analysis of the oil composition.

Abstract translation: 采用微滴的系统用于Microdroplet电喷雾离子化质谱（ESI MS）的实施方案中。 因此，检测分析物的方法包括提供包含油的油组合物和包含分析物的水性微滴，所述油组合物包含表面活性剂以稳定所述油组合物中的水微滴滴; 并进行油组成的电离质谱分析。

公开(公告)号：US20160162392A1

公开(公告)日：2016-06-09

申请号：US14565220

申请日：2014-12-09

Applicant: Ziheng Hu ,  Jing Li ,  Xin Li ,  Chen Zhou ,  Longhui Chang

Inventor： Ziheng Hu ,  Jing Li ,  Xin Li ,  Chen Zhou ,  Longhui Chang

IPC: G06F11/36

CPC classification number: G06F11/3684 ,  G06F11/3688

Abstract: An automated, self-adaptive framework prioritizes software testing in a consistent and effective manner. A metric evaluates past test execution information for assigning regression testing priority. The metric may be calculated with reference to one or more of the following factors taken in combination: requirement, coverage, history, and cost. The requirement factor considers customer-assigned priority of testing the code, complexity of implementing the code, and proneness of the code to faults. The coverage factor considers code coverage, feature coverage, and common usage rate. The history factor considers previous bug found rate, case stable rate, and priority to calculate. The cost factor considers test case execution time, and step length. A value of each factor for one test case is measured according to that test case and is not related to other test cases. The calculation result representing the metric for each test case determines a priority of the test case.

Abstract translation: 自动化的自适应框架以一致和有效的方式优先考虑软件测试。 指标评估过去的测试执行信息，以分配回归测试优先级。 可以参考以下组合中的一个或多个因素来计算度量：要求，覆盖率，历史和成本。 要求因素考虑了客户分配的测试代码的优先级，实现代码的复杂性和代码的错误。 覆盖率考虑代码覆盖率，功能覆盖率和常用使用率。 历史因素考虑以前的错误发现率，病例稳定率和优先级来计算。 成本因素考虑测试用例执行时间和步长。 一个测试用例的每个因子的值根据该测试用例进行测量，与其他测试用例无关。 表示每个测试用例的度量的计算结果决定了测试用例的优先级。

公开(公告)号：US09267918B2

公开(公告)日：2016-02-23

申请号：US13725459

申请日：2012-12-21

Applicant: Tony R. Joaquim ,  Lewis Joe Stafford ,  Ross Stewart Chambers ,  Xin Liu ,  Clive Adrian Smith ,  Xin Li ,  Graeme Whyte

Inventor： Tony R. Joaquim ,  Lewis Joe Stafford ,  Ross Stewart Chambers ,  Xin Liu ,  Clive Adrian Smith ,  Xin Li ,  Graeme Whyte

IPC: G01N27/447 ,  G01N15/14 ,  B01L3/00 ,  B01L3/02

CPC classification number: G01N27/44791 ,  B01L3/0268 ,  B01L3/502784 ,  B01L2200/0652 ,  B01L2200/0673 ,  B01L2400/0415 ,  B01L2400/043 ,  G01N15/1484 ,  G01N2015/149

Abstract: A flow cell for a microfluidic device can include a chamber, first microfluidic entry and exit channels, second microfluidic entry and exit channels, a first electrode, and a second electrode. A microfluidic device can include a microfluidic channel, a laser to excite fluorescent material, and a detector to detect fluorescence emission. Methods of merging a droplet from an emulsion in to a second stream of fluid and of detecting a content of a droplet in a stream are further disclosed.

Abstract translation: 用于微流体装置的流动池可以包括室，第一微流体入口和出口通道，第二微流体入口和出口通道，第一电极和第二电极。 微流体装置可以包括微流体通道，激发荧光材料的激光器和检测器以检测荧光发射。 进一步公开了将液滴从乳液合并到第二流体流中并且检测流中的液滴含量的方法。

公开(公告)号：US20150141804A1

公开(公告)日：2015-05-21

申请号：US14543071

申请日：2014-11-17

Applicant: William Rooney ,  Charles Springer, JR. ,  Xin Li

Inventor： William Rooney ,  Charles Springer, JR. ,  Xin Li

IPC: A61B5/026 ,  A61B5/00 ,  G01R33/48 ,  A61B5/0295 ,  G01R33/563 ,  G01R33/56

CPC classification number: A61B5/0263 ,  A61B5/0013 ,  A61B5/0037 ,  A61B5/0295 ,  A61B5/055 ,  A61B5/4064 ,  A61B5/4082 ,  A61B5/4088 ,  A61B5/4866 ,  A61B5/7282 ,  A61B5/742 ,  A61B5/748 ,  G01R33/4828 ,  G01R33/5601 ,  G01R33/5608 ,  G01R33/56366

Abstract: Provided herein are methods and apparatuses for determining a level of cellular metabolic activity for a region of interest in order to detect and map on-going gliovascular unit metabolic activity using high-resolution 1H2O MRI. In one example approach, a computer-implemented method includes receiving a first set of DCE-MRI time-course data for a region, wherein a contrast agent is administered prior to imaging, identifying a region of interest from the first set of DCE-MRI time-course data for further analysis, performing shutter-speed pharmacokinetic analysis of the time-course data associated with the region of interest using computer-implemented software to obtain a finite and non-zero mean water molecule capillary lifetime in the region of interest, and indicating a level of cellular metabolic activity in the brain based on the mean water molecule capillary lifetime.

Abstract translation: 本文提供了用于确定感兴趣区域的细胞代谢活动水平的方法和装置，以便使用高分辨率1H2O MRI来检测和映射正在进行的心血管单位代谢活动。 在一个示例性方法中，计算机实现的方法包括接收用于区域的第一组DCE-MRI时间段数据，其中在成像之前施用造影剂，从第一组DCE-MRI识别感兴趣区域 用于进一步分析的时间过程数据，使用计算机实现的软件执行与感兴趣区域相关联的时间线数据的快门速度药代动力学分析，以获得感兴趣区域中的有限和非零平均水分子毛细血管寿命， 并基于平均水分子毛细管寿命指示脑中的细胞代谢活性水平。

公开(公告)号：US09009144B1

公开(公告)日：2015-04-14

申请号：US13434773

申请日：2012-03-29

Applicant: Xin Li ,  Shi Chen ,  Qiying Lin

Inventor： Xin Li ,  Shi Chen ,  Qiying Lin

IPC: G06F7/00 ,  G06F17/30

CPC classification number: G06F17/30389

Abstract: Dynamic identification and removal of potential stopwords from a search query is provided. A search query comprising plural terms is received. A possible stopword among the terms that appears in a predefined list of possible stopwords is identified. Query splits are determined based on one or more query patterns, each query split comprising a location portion using a first subset of the plural terms and a subject portion using a second subset. Either the location portion or the subject portion of the query splits is modified, by removing the possible stopword from that portion. The search engine is queried with the location portion and the subject portion for each of the query splits, and scored search results are obtained for each of the query splits. The search results returned for at least one of the query splits is selected to return as a response to the search query.

Abstract translation: 提供动态识别和删除搜索查询中的潜在停用词。 接收包括多个术语的搜索查询。 确定出现在可能的停用词的预定义列表中的术语中的可能的词语。 基于一个或多个查询模式确定查询分割，每个查询分割包括使用多个术语的第一子集的位置部分和使用第二子集的对象部分。 通过从该部分移除可能的停止词来修改查询分割的位置部分或主题部分。 对每个查询分割的位置部分和主题部分查询搜索引擎，并且为每个查询分割获得得分的搜索结果。 选择为至少一个查询分割返回的搜索结果作为对搜索查询的响应返回。

公开(公告)号：US08921571B2

公开(公告)日：2014-12-30

申请号：US13500695

申请日：2010-10-06

Applicant: Michael K. Chan ,  Tomasz Fekner ,  Xin Li ,  Marianne Lee ,  Manoj Nair ,  Jennifer Jo Ottensen

Inventor： Michael K. Chan ,  Tomasz Fekner ,  Xin Li ,  Marianne Lee ,  Manoj Nair ,  Jennifer Jo Ottensen

IPC: C07D277/06 ,  C07D229/02 ,  C07C53/124 ,  C07C233/47 ,  C07C247/04 ,  C07C247/12 ,  C07C229/28 ,  C07C323/60 ,  C07C237/16 ,  C07C323/25

CPC classification number: C07D277/06 ,  C07C229/28 ,  C07C237/16 ,  C07C247/12 ,  C07C323/25 ,  C07C323/60 ,  C07D229/02

Abstract: Several different pyrrolysine analogs are disclosed in this application. Those analogs have distinct chemical and biophysical properties. Some analogs are useful in chemical ligation applications. Methods of making and using are also disclosed.

Abstract translation: 本申请中公开了几种不同的吡咯赖斯类似物。 那些类似物具有不同的化学和生物物理性质。 一些类似物在化学连接应用中是有用的。 还公开了制造和使用方法。

公开(公告)号：US20140206046A1

公开(公告)日：2014-07-24

申请号：US14240663

申请日：2012-09-07

Applicant: Hui Xu ,  Ye Chen ,  Xin Li ,  Mark Stevens ,  Zhengfang Kang

Inventor： Hui Xu ,  Ye Chen ,  Xin Li ,  Mark Stevens ,  Zhengfang Kang

IPC: C12P19/14 ,  C12P7/14

CPC classification number: C12P7/14 ,  C12P7/10 ,  C12P19/14 ,  Y02E50/16

Abstract: Described herein are improved methods of degrading or converting cellulosic material into fermentable sugars using dithionite. Also described are improved methods of fermentation in the presence of dithionite.

Abstract translation: 本文描述了使用连二亚硫酸盐将纤维素材料降解或转化成可发酵糖的改进方法。 还描述了在连二亚硫酸盐存在下发酵的改进方法。