公开(公告)号：US20150327932A1

公开(公告)日：2015-11-19

申请号：US14808945

申请日：2015-07-24

Applicant: Arcuo Medical, Inc.

Inventor： Emil Naumovich Sobol ,  Alexander P. Sviridov ,  Michael M. Gorin

IPC: A61B18/22 ,  A61N5/06 ,  A61B10/04 ,  A61B5/00

CPC classification number: A61B5/4839 ,  A61B5/0084 ,  A61B10/04 ,  A61B18/201 ,  A61B2018/00273 ,  A61B2018/00577 ,  A61B2018/00648 ,  A61B2018/00732 ,  A61B2018/00791 ,  A61B2018/00904 ,  A61B2018/00982 ,  A61B2018/20361 ,  A61B2218/007 ,  A61B2562/228 ,  A61N5/0601 ,  A61N2005/067

Abstract: The efficacy and safety of laser medical treatments are ensured by performing a combination of measurement techniques to examine tissue properties in order to control characteristics of the laser treatments of cartilaginous tissues. In some aspects, a treatment tool is provided that is capable of taking and providing feedback relating to multiple measurements, including temperature measurements (in particular, radiometry), mechanical measurements, light scattering, speckle interferometry, optoacoustic measurements, and monitoring tissue electrical characteristics. The device is capable of providing feedback during the course of laser treatment of tissue to increase the safety and efficacy of treatment.

Abstract translation: 激光治疗的功效和安全性通过执行测量技术的组合来检查组织性质来确保，以控制软骨组织的激光治疗的特征。 在一些方面，提供了一种处理工具，其能够获取和提供与多个测量相关的反馈，包括温度测量（特别是辐射测量），机械测量，光散射，散斑干涉测量，光声测量和监测组织电特性。 该装置能够在激光治疗组织过程中提供反馈，以提高治疗的安全性和有效性。

公开(公告)号：US09125677B2

公开(公告)日：2015-09-08

申请号：US13011891

申请日：2011-01-22

Applicant: Emil Naumovich Sobol ,  Alexander P. Sviridov ,  Michael M. Gorin

Inventor： Emil Naumovich Sobol ,  Alexander P. Sviridov ,  Michael M. Gorin

IPC: A61N5/06 ,  A61B18/20 ,  A61B18/00

CPC classification number: A61B18/22 ,  A61B5/0084 ,  A61B5/4839 ,  A61B10/04 ,  A61B18/201 ,  A61B2018/00273 ,  A61B2018/00577 ,  A61B2018/00648 ,  A61B2018/00732 ,  A61B2018/00791 ,  A61B2018/00904 ,  A61B2018/00982 ,  A61B2018/202 ,  A61B2018/225 ,  A61B2218/007 ,  A61B2562/228 ,  A61N5/0601 ,  A61N2005/067

Abstract: The efficacy and safety of laser medical treatments are ensured by performing a combination of measurement techniques to examine tissue properties in order to control characteristics of the laser treatments of cartilaginous tissues. In some aspects, a treatment tool is provided that is capable of taking and providing feedback relating to multiple measurements, including temperature measurements (in particular, radiometry), mechanical measurements, light scattering, speckle interferometry, optoacoustic measurements, and monitoring tissue electrical characteristics. The device is capable of providing feedback during the course of laser treatment of tissue to increase the safety and efficacy of treatment.

Abstract translation: 激光治疗的功效和安全性通过执行测量技术的组合来检查组织性质来确保，以控制软骨组织的激光治疗的特征。 在一些方面，提供了一种处理工具，其能够获取和提供与多个测量相关的反馈，包括温度测量（特别是辐射测量），机械测量，光散射，散斑干涉测量，光声测量和监测组织电特性。 该装置能够在激光治疗组织过程中提供反馈，以提高治疗的安全性和有效性。

公开(公告)号：US20150202005A1

公开(公告)日：2015-07-23

申请号：US14599984

申请日：2015-01-19

Applicant: OmniGuide, Inc.

Inventor： Vladimir Fuflyigin ,  Lori Pressman

IPC: A61B18/20 ,  A61B19/00

CPC classification number: A61B18/20 ,  A61B18/201 ,  A61B18/203 ,  A61B90/30 ,  A61B2017/00066 ,  A61B2018/00029 ,  A61B2018/00577 ,  A61B2018/00589 ,  A61B2018/00595 ,  A61B2018/00601 ,  A61B2018/00642 ,  A61B2018/0066 ,  A61B2018/00702 ,  A61B2018/00726 ,  A61B2018/00732 ,  A61B2018/00744 ,  A61B2018/00761 ,  A61B2018/1807 ,  A61B2018/2065 ,  A61B2090/3941

Abstract: A system and method for optimizing treatment of tissue of a patient at a surgical site by directing at least a first wavelength of illuminating radiation to a target location on the tissue of the patient to cause at least one type of fluorophore associated with the tissue to fluoresce. At least a first surgical energy is directed to the target location at one of a plurality of power settings, at least one of the power settings capable of quenching fluorescence of the fluorophore. At least one of a plurality of system control settings is adjusted to alter the amount of quenching of the fluorophore, the system control settings including the plurality of power settings.

Abstract translation: 一种用于通过将至少第一波长的照射辐射引导到患者组织上的目标位置来优化在手术部位处的患者组织的系统和方法，以使至少一种类型的与组织相关联的荧光团发荧光 。 至少第一手术能量以多个功率设置中的一个被引导到目标位置，能够熄灭荧光团的荧光的功率设置中的至少一个。 调整多个系统控制设置中的至少一个以改变荧光团的淬灭量，所述系统控制设置包括多个功率设置。

公开(公告)号：US20150173622A1

公开(公告)日：2015-06-25

申请号：US14134668

申请日：2013-12-19

Applicant: Novartis AG

Inventor： Kambiz Parto ,  Barry Wheatley ,  Edouard Schmidtlin ,  Tammo Heeren ,  Mauricio Jochinsen ,  Lingfeng Yu

IPC: A61B5/00 ,  A61B18/20 ,  A61B1/07

CPC classification number: A61B18/20 ,  A61B5/0066 ,  A61B5/0084 ,  A61B18/201 ,  A61B18/22 ,  A61B2018/00577 ,  A61B2018/00589 ,  A61B2018/00982 ,  A61B2018/20357 ,  A61B2560/0431

Abstract: An optical light scanning probe is presented, the probe comprising a handle, shaped for grasping by a user; a cannula, protruding from a distal portion of the handle with an outer diameter smaller than 20 gauge; an optical fiber with a distal fiber-portion off a probe-axis, configured to receive a light from a light-source at a proximal fiber-portion, and to emit the received light at the distal fiber-portion; a fixed beam forming unit, disposed at a distal portion of the cannula, configured to receive the light from the distal fiber-portion, and to deflect the received light toward a target region; and a fiber actuator, housed at least partially in the handle, configured to move the distal fiber-portion to scan the deflected light along a scanning curve in the target region.

Abstract translation: 提供了一种光学扫描探针，该探针包括一个被用户抓握的手柄; 套管，其从所述手柄的远端突出，外径小于20号; 光纤，其远离光纤部分离开探针轴，被配置为在近端光纤部分处接收来自光源的光，并在远端光纤部分发射接收的光; 固定光束形成单元，设置在所述套管的远端部分处，被配置为接收来自所述远端纤维部分的光，并将接收的光偏转到目标区域; 以及纤维致动器，其至少部分地容纳在所述把手中，所述纤维致动器被构造成移动所述远端光纤部分以沿着所述目标区域中的扫描曲线扫描所述偏转的光。

公开(公告)号：US20150150629A1

公开(公告)日：2015-06-04

申请号：US14413105

申请日：2013-07-05

Applicant: THE GENERAL HOSPITAL CORPORATION

Inventor： Richard Rox Anderson ,  Mathew Avram ,  Wikunda Limpiangkanan ,  William A. Farinelli

IPC: A61B18/20 ,  A61B17/00 ,  A61H1/00 ,  A61H1/02 ,  A61B17/064 ,  A61B17/06

CPC classification number: A61B18/203 ,  A61B17/0466 ,  A61B17/0644 ,  A61B17/083 ,  A61B18/201 ,  A61B2017/005 ,  A61B2017/00761 ,  A61B2017/00765 ,  A61B2018/0047 ,  A61B2018/00577 ,  A61B2018/2211

Abstract: Exemplary methods and systems can be provided for resurfacing of skin that include formation of a plurality of small holes, e.g., having widths greater than about 0.2 mm and less than about 0.7 mm or 0.5 mm, using ablative electromagnetic radiation, e.g., optical energy. An optically transparent plate or window can be pressed over a surface of the skin tissue as the holes are ablated to disrupt formation of a thermal cuff around the holes. Compressive or tensile forces can then be applied to the treated region of the skin tissue as the damage heals to facilitate hole closure and provide enhanced and/or directional shrinkage of the treated skin area.

Abstract translation: 可以提供用于皮肤表面重建的示例性方法和系统，包括使用例如光学能量的消融电磁辐射形成多个小孔，例如具有大于约0.2mm且小于约0.7mm或0.5mm的宽度。 当孔被烧蚀时，光学透明的板或窗可被压在皮肤组织的表面上，以破坏围绕孔的热套箍的形成。 然后，随着损伤愈合以促进闭孔并且提供经处理的皮肤区域的增强和/或定向收缩，可以将压缩或拉伸力施加到皮肤组织的经处理区域。

公开(公告)号：US09044302B2

公开(公告)日：2015-06-02

申请号：US13279126

申请日：2011-10-21

Applicant: Philip Gooding ,  Christine Beltran

Inventor： Philip Gooding ,  Christine Beltran

IPC: A61B13/00 ,  A61B18/18 ,  A61F9/008 ,  A61B3/14 ,  A61B5/00 ,  A61B18/20 ,  A61B8/10

CPC classification number: A61F9/009 ,  A61B3/14 ,  A61B5/0059 ,  A61B8/10 ,  A61B18/201 ,  A61F9/00802 ,  A61F9/00825 ,  A61F2009/0087 ,  A61F2009/00887 ,  A61F2009/00889 ,  A61F2009/00897

Abstract: One embodiment is directed to a patient interface system for ophthalmic intervention on an eye of a patient, comprising: a housing; an optical lens coupled to the housing and having a focal axis; a eye surface engagement assembly coupled to the housing and comprising an inner seal having an inner seal diameter and being configured to circumferentially engage the eye, an outer seal having an outer seal diameter and being configured to circumferentially engage the eye, and a tissue migration bolster structure configured to be positioned circumferentially between the inner and outer circumferential seals and to prevent migration of tissue of the eye toward the eye surface engagement assembly when a vacuum load is applied within the assembly to cause vacuum engagement of the inner and outer seals against the eye.

Abstract translation: 一个实施例涉及用于患者眼睛上的眼科干预的患者接口系统，包括：壳体; 耦合到壳体并具有焦轴的光学透镜; 眼表面接合组件，其联接到所述壳体并且包括内密封件，所述内密封件具有内密封件直径并且构造成周向接合所述眼睛;外密封件，其具有外密封件直径并且构造成周向接合所述眼部;以及组织移植垫 结构构造成周向地定位在内外周密封之间并且当在组件内施加真空负载以防止内密封件和外密封件与眼睛的真空接合时，防止眼睛组织向眼表面接合组件移动 。

公开(公告)号：US09033964B2

公开(公告)日：2015-05-19

申请号：US13822378

申请日：2011-09-30

Applicant: Seong-Mok Cho ,  Moon Youn Jung ,  Seunghwan Kim

Inventor： Seong-Mok Cho ,  Moon Youn Jung ,  Seunghwan Kim

IPC: G21K5/04 ,  A61B18/20 ,  A61N5/10 ,  H05H6/00

CPC classification number: G21K5/04 ,  A61B18/201 ,  A61N5/1077 ,  A61N2005/1088 ,  H05H6/00

Abstract: Provided are a target structure used for generating a charged particle beam, a method of manufacturing the same, and a medical appliance using the same. The target structure includes a target layer and a support having a through hole used as a progressing path of a laser beam or a charged particle beam.

Abstract translation: 提供了用于产生带电粒子束的目标结构，其制造方法和使用该粒子束的医疗器具。 目标结构包括目标层和具有用作激光束或带电粒子束的前进路径的通孔的支撑体。

公开(公告)号：US20140263214A1

公开(公告)日：2014-09-18

申请号：US14216966

申请日：2014-03-17

Applicant: University of North Texas

Inventor： Narendra B. Dahotre ,  Soundarapandian Santhanakrishnan

IPC: B23K26/00 ,  B23K26/04 ,  B23K26/36

CPC classification number: A61B18/203 ,  A61B18/201 ,  B23K26/00 ,  B23K26/36 ,  G06F19/00

Abstract: An apparatus and method for laser-assisted machining (LAM) of bone without raising the temperature of the surrounding bone is discussed. The method of LAM of bone involves determining a target bone needing to be machined an then scanning a high power density laser beam along the bone at a machining rate that produces low-heat affected zones (HAZ) on the target bone. The process and apparatus is advantageous over conventional technologies because it provides a chemically clean, coherent, and monochromatic beam to the region to be machined.

Abstract translation: 讨论了骨骼激光辅助加工（LAM）的装置和方法，而不提高周围骨骼的温度。 骨的LAM的方法涉及确定需要加工的目标骨，然后以在骨骼上产生低热影响区（HAZ）的加工速率沿着骨扫描高功率密度激光束。 该方法和装置优于常规技术，因为它向要加工的区域提供化学清洁，相干和单色光束。

公开(公告)号：US20140221826A1

公开(公告)日：2014-08-07

申请号：US14122500

申请日：2011-05-31

Applicant: Karen Joos ,  Jin Hui Shen

Inventor： Karen Joos ,  Jin Hui Shen

IPC: A61B5/00 ,  A61B1/04 ,  A61B1/07 ,  A61B3/10 ,  G01B9/02

CPC classification number: A61B5/0066 ,  A61B1/04 ,  A61B1/07 ,  A61B3/102 ,  A61B5/0084 ,  A61B18/20 ,  A61B18/201 ,  A61B18/22 ,  A61B2090/3735 ,  G01B9/02091

Abstract: A miniature intraoperative probe (30) capable of forward-imaging with optical coherence tomography. The probe includes a housing (130), an actuator (150) supported by the housing, and a single mode (146) fiber supported by the housing and configured to laterally scan light data reflected from a sample.

Abstract translation: 一种能够用光学相干断层扫描进行前向成像的微型术中探针（30）。 探针包括壳体（130），由壳体支撑的致动器（150）和由壳体支撑并被配置为横向扫描从样品反射的光数据的单模（146）光纤。

公开(公告)号：US20140188128A1

公开(公告)日：2014-07-03

申请号：US13759969

申请日：2013-02-05

Applicant: Paul Joseph Weber

Inventor： Paul Joseph Weber

IPC: A61B19/00 ,  A61B18/08

CPC classification number: A61B18/14 ,  A61B18/082 ,  A61B18/1402 ,  A61B18/148 ,  A61B18/1482 ,  A61B18/149 ,  A61B18/1815 ,  A61B18/201 ,  A61B34/30 ,  A61B90/98 ,  A61B2017/00106 ,  A61B2017/00221 ,  A61B2018/00023 ,  A61B2018/00303 ,  A61B2018/00589 ,  A61B2018/00601 ,  A61B2018/00619 ,  A61B2018/00642 ,  A61B2018/0066 ,  A61B2018/00666 ,  A61B2018/00708 ,  A61B2018/00714 ,  A61B2018/0072 ,  A61B2018/00761 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/00815 ,  A61B2018/00821 ,  A61B2018/00863 ,  A61B2018/00875 ,  A61B2018/00898 ,  A61B2018/00982 ,  A61B2018/1807 ,  A61B2018/2211 ,  A61B2090/3945 ,  A61B2218/002 ,  A61B2218/007 ,  A61N7/00 ,  A61N2007/0047

Abstract: Systems, apparatus and methods for tissue dissection and modification are disclosed herein. A method for tissue dissection and modification may comprise inserting a tissue dissecting and modifying wand (TDM) through an incision in a patient's body. The TDM may comprise a tip having a plurality of protrusions with lysing segments positioned between the protrusions to dissect and/or modify tissue. The TDM may also comprise an energy window positioned on top of the TDM that is configured to deliver energy to modify tissues. After separating tissue using the lysing segment(s) to define a target region, the energy window may be activated and moved around within the target region to modify tissues. In some implementations, the energy window may be activated prior to and/or during dissection of the tissue such that the tissue is separated while tissue is modified within the target region.

Abstract translation: 本文公开了用于组织解剖和修饰的系统，装置和方法。 用于组织解剖和修饰的方法可以包括通过患者体内的切口插入组织解剖和修改棒（TDM）。 TDM可以包括具有多个突起的末端，其中裂解段定位在突起之间以解剖和/或修饰组织。 TDM还可以包括位于TDM顶部的能量窗口，其被配置为递送能量以修改组织。 在使用裂解段分离组织以限定目标区域之后，能量窗口可以被激活并在目标区域内移动以修改组织。 在一些实施方案中，能量窗口可以在组织解剖之前和/或期间激活，使得组织在组织在目标区域内被修饰时被分离。