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    Triazoline and isoxazoline bis-oxime derivatives and their use as pesticides
    11.
    发明授权
    Triazoline and isoxazoline bis-oxime derivatives and their use as pesticides 失效
    三唑啉和异恶唑啉双肟衍生物及其作为农药的用途

    公开(公告)号：US5932583A

    公开(公告)日：1999-08-03

    申请号：US981116

    申请日：1997-12-23

    Applicant: Hugo Ziegler ,  Stephan Trah ,  Rene Zurfluh ,  Anthony Cornelius O'Sullivan

    Inventor： Hugo Ziegler ,  Stephan Trah ,  Rene Zurfluh ,  Anthony Cornelius O'Sullivan

    IPC: A01N43/647 ,  A01N43/653 ,  A01N43/80 ,  C07C251/52 ,  C07C251/58 ,  C07C251/60 ,  C07C265/12 ,  C07C279/18 ,  C07C281/06 ,  C07C331/28 ,  C07C335/18 ,  C07D249/08 ,  C07D249/12 ,  C07D261/10 ,  C07D261/12 ,  C07D401/12 ,  C07D403/12 ,  C07D413/12 ,  C07D417/12 ,  A61K31/41 ,  A61K31/42 ,  C07C249/08

    CPC classification number: C07D261/10 ,  A01N43/647 ,  A01N43/80 ,  C07C251/52 ,  C07C251/58 ,  C07C251/60 ,  C07C265/12 ,  C07C279/18 ,  C07C331/28 ,  C07C335/18 ,  C07D249/12 ,  C07D261/12 ,  C07D401/12 ,  C07D403/12 ,  C07D413/12 ,  C07D417/12

    Abstract: Bis-oxime derivatives of the formula I ##STR1## W is oxygen or sulfur, and the other substituents defined as follows: R.sub.1 =hydrogen, C.sub.1 -C.sub.4 alkyl; cyclopropyl;R.sub.2 =hydrogen, C.sub.1 -C.sub.6 alkyl; halo(C.sub.1 -C.sub.6) alkyl; C.sub.2 -C.sub.6 alkoxyalkyl; C.sub.3 -C.sub.6 cycloalkyl; substituted or unsubstituted aryl; substituted or unsubstituted heteroaryl; cyano; C.sub.1 -C.sub.6 alkoxycarbonyl; C.sub.1 -C.sub.6 alkyl-S(O).sub.n ; substituted or unsubstituted aryl-S(O).sub.n ; C.sub.1 -C.sub.6 alkoxy; substituted or unsubstituted aryloxy; substituted or unsubstituted heteroaryloxy; unsubstituted or mono- to trimethyl-substituted heterocyclyl; substituted or unsubstituted aryl-C.sub.1 -C.sub.6 alkyl; substituted or unsubstituted heteroaryl-C.sub.1 -C.sub.6 alkyl;R.sub.3 =hydrogen; C.sub.1 -C.sub.6 alkyl; C.sub.1 -C.sub.6 haloalkyl having 1 to 5 halogen atoms; C.sub.1 -C.sub.4 alkoxy-C.sub.1 -C.sub.2 -alkyl; unsubstituted or mono- to trihalo-substituted C.sub.1 -C.sub.6 alkenyl; C.sub.2 -C.sub.6 alkynyl; unsubstituted or mono- to tetrahalo-substituted C.sub.3 -C.sub.6 cycloalkyl-C.sub.1 -C.sub.4 alkyl;n=0 to 2;R.sub.8 =H, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 haloalkyl, C.sub.3 -C.sub.6 cycloalkyl;X=OR.sub.5, SR.sub.5, NR.sub.6 R.sub.7, halogen (especially Cl);R.sub.6, R.sub.7 =independently of one another H, C.sub.1 -C.sub.4 alkyl, C.sub.3 -C.sub.4 alkenyl, C.sub.3 -C.sub.4 alkynyl;R.sub.5 =C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.3 haloalkyl, are fungicidal, acaricidal and insecticidal active ingredients for agriculture. They can be employed as formulated crop protection compositions.

    Abstract translation: PCT No.PCT / EP96 / 02695 Sec。 371 1997年12月23日第 102（e）1997年12月23日PCT PCT 1996年6月21日PCT公布。 出版物WO97 / 02255 日期1997年1月23日式I W的双肟衍生物是氧或硫，其它取代基定义如下：R1 =氢，C1-C4烷基; 环丙基 R2 =氢，C1-C6烷基; 卤代（C 1 -C 6）烷基; C2-C6烷氧基烷基; C 3 -C 6环烷基; 取代或未取代的芳基; 取代或未取代的杂芳基; 氰基; C1-C6烷氧基羰基; C 1 -C 6烷基-S（O）n; 取代或未取代的芳基-S（O）n; C1-C6烷氧基; 取代或未取代的芳氧基; 取代或未取代的杂芳氧基; 未取代或单 - 三甲基取代的杂环基; 取代或未取代的芳基-C 1 -C 6烷基; 取代或未取代的杂芳基-C 1 -C 6烷基; R3 =氢; C1-C6烷基; 具有1至5个卤素原子的C 1 -C 6卤代烷基; C 1 -C 4烷氧基-C 1 -C 2 - 烷基; 未取代或单 - 三卤代取代的C 1 -C 6烯基; C2-C6炔基; 未取代或单 - 四卤代取代的C 3 -C 6环烷基-C 1 -C 4烷基; n = 0〜2; R8 = H，C1-C4烷基，C1-C4卤代烷基，C3-C6环烷基; X = OR5，SR5，NR6R7，卤素（特别是Cl）; R6，R7 =彼此独立地为H，C1-C4烷基，C3-C4链烯基，C3-C4炔基; R5 = C1-C4烷基，C1-C3卤代烷基，是农业的杀真菌，杀螨和杀虫活性成分。 它们可以用作配制的作物保护组合物。

    PYRIDAZINE DERIVATIVES USEFUL AS FUNGICIDES AND FOR THE TREATMENT OF CANCER
    13.
    发明申请
    PYRIDAZINE DERIVATIVES USEFUL AS FUNGICIDES AND FOR THE TREATMENT OF CANCER 审中-公开
    用作杀真菌剂和治疗癌症的吡咯烷酮衍生物

    公开(公告)号：US20100273804A1

    公开(公告)日：2010-10-28

    申请号：US12809604

    申请日：2008-12-19

    Applicant: Clemens Lamberth ,  Stephan Trah ,  Raphael Dumeunier ,  Sebastian Volker Wendeborn

    Inventor： Clemens Lamberth ,  Stephan Trah ,  Raphael Dumeunier ,  Sebastian Volker Wendeborn

    IPC: A61K31/501 ,  A01N43/58 ,  C07D403/04 ,  C07D237/08 ,  A01P3/00 ,  A61K31/50 ,  A61P35/00

    CPC classification number: C07D237/12 ,  A01N43/58 ,  C07D237/14

    Abstract: The present invention relates to novel pyridazine derivatives of formula (I) as active ingredients which have microbiocidal activity, in particular fungicidal activity: formula (I) wherein R1 is C1-C6alkyl, C1-C6haloalkyl or C3-C6cycloalkyl; R2 is hydrogen or an optionally substituted alkyl, aryl or heteroaryl; R3 is hydrogen, C1-C6alkyl or C1-C6haloalkyl; R4 is hydrogen, C1-C6alkyl or C1-C6haloalkyl; or R3 and R4 together can be part of a carbocyclic or heterocyclic 3- to 8-membered ring; R5 is optionally substituted aryl or heteroaryl; and R6 is hydroxy, halogen, C1-C6alkoxy, C1-C6haloalkoxy, C1-C6alkylthio or C1-C6haloalkylthio; or an agrochemically usable salt form thereof.

    Abstract translation: 本发明涉及具有杀微生物活性，特别是杀真菌活性的作为活性成分的式（I）的新哒嗪衍生物：式（I）其中R 1是C 1 -C 6烷基，C 1 -C 6卤代烷基或C 3 -C 6环烷基; R 2是氢或任选取代的烷基，芳基或杂芳基; R3是氢，C1-C6烷基或C1-C6卤代烷基; R4是氢，C1-C6烷基或C1-C6卤代烷基; 或者R 3和R 4一起可以是碳环或杂环的3至8元环的一部分; R5是任选取代的芳基或杂芳基; R 6为羟基，卤素，C 1 -C 6烷氧基，C 1 -C 6卤代烷氧基，C 1 -C 6烷硫基或C 1 -C 6卤代烷硫基; 或其农业化学上可用的盐形式。

    Insecticides
    14.
    发明授权
    Insecticides 有权
    杀虫剂

    公开(公告)号：US07812170B2

    公开(公告)日：2010-10-12

    申请号：US10598041

    申请日：2005-03-02

    Applicant: David John Hughes ,  James Edward Peace ,  Suzanna Riley ,  Sally Russell ,  Joseph John Swanborough ,  Roger Graham Hall ,  André Jeanguenat ,  Olivier Loiseleur ,  Peter Renold ,  Stephan Trah ,  Jean Wenger

    Inventor： David John Hughes ,  James Edward Peace ,  Suzanna Riley ,  Sally Russell ,  Joseph John Swanborough ,  Roger Graham Hall ,  André Jeanguenat ,  Olivier Loiseleur ,  Peter Renold ,  Stephan Trah ,  Jean Wenger

    IPC: C07D401/00

    CPC classification number: C07D401/04 ,  A01N37/46 ,  A01N43/40 ,  A01N43/56 ,  C07D401/14 ,  C07D405/14 ,  C07D409/14 ,  C07D413/14 ,  C07D417/14 ,  C07D491/04 ,  C07D493/08 ,  C07D495/04 ,  C07D513/04

    Abstract: Compounds of the formula (I) in which Z, is an oxygen atom; or a sulfur atom; Z2 is an oxygen atom; or a sulfur atom; R, is an aryl or heteroaryl group, which is unsubstituted or substituted; R2 is hydrogen; or an organic substituent; R3 is hydrogen; or an organic substituent; R4 is hydrogen; or an organic substituent; or R3 and R4, taken together, form, together with the nitrogen atom, to which they are attached, a ring, which is unsubstituted or substituted; R5 is hydrogen; or an unsubstituted or substituted alkyl group; or forms, taken together with R8 or with a monovalent substituent attached to that atom of R6, via which atom R6 is directly connected with the carbon atom, shown in the formula I, which carries R5, one additional bond; R6 and R7, taken together, form, together with the two carbon atoms, shown in the formula I, to which atoms they are attached, a bicyclic ring system, which ring system is carbocyclic or heterocyclic, which ring system is substituted, in the manner shown in the formula I, by the four substituents —N(R2)-C(═Z1)-R, —C(═Z2)-N(R3)-R4, R5 and R8, and which ring system is optionally further substituted; and R8 is hydrogen; or an unsubstituted or substituted alkyl group; or forms, taken together with R5 or with a monovalent substituent attached to that atom of R7, via which atom R7 is directly connected with the carbon atom, shown in the formula I, which carries R8, one additional bond, and, where appropriate, tautomers thereof, in each case in free form or in salt form, can be used as agrochemical active ingredients and can be prepared in a manner known per se.

    Abstract translation: 其中Z为氧原子的式（I）化合物; 或硫原子; Z2是氧原子; 或硫原子; R 1是未取代或取代的芳基或杂芳基; R2是氢; 或有机取代基; R3是氢; 或有机取代基; R4是氢; 或有机取代基; 或者R 3和R 4一起与它们所连接的氮原子一起形成未被取代或被取代的环， R5是氢; 或未取代或取代的烷基; 或其形式，与R8一起或与R6的该原子连接的一价取代基，其中原子R6直接与碳原子连接，如式I所示，其携带R5，另外一个键; R6和R7一起与式I中所示的两个碳原子一起形成，其中它们连接的原子是双环系统，该环系是碳环或杂环的，该环系被取代，在 式（I）所示的四种取代基-N（R 2）-C（= Z 1）-R，-C（= Z 2）-N（R 3）-R 4，R 5和R 8， 取代 R8是氢; 或未取代或取代的烷基; 或其形式与R5一起或与R7的原子连接的一价取代基，其中原子R7与碳原子直接连接，如式I所示，其携带R8，一个附加键，并且在适当的情况下， 互变异构体，以游离形式或盐形式，可以用作农业化学活性成分，并且可以以本身已知的方式制备。

    Dihalo-allyloxy-phenol derivatives having pesticidal activity
    17.
    发明申请
    Dihalo-allyloxy-phenol derivatives having pesticidal activity 审中-公开

    公开(公告)号：US20060014806A1

    公开(公告)日：2006-01-19

    申请号：US10537444

    申请日：2003-12-10

    Applicant: Werner Zambach ,  Peter Renold ,  Stephan Trah ,  Poger Hall

    Inventor： Werner Zambach ,  Peter Renold ,  Stephan Trah ,  Poger Hall

    IPC: C07D213/42

    CPC classification number: A01N37/34 ,  C07C43/225 ,  C07C43/23 ,  C07C43/315 ,  C07C45/29 ,  C07C45/71 ,  C07C49/255 ,  C07C69/76 ,  C07C205/32 ,  C07C251/40 ,  C07C255/37 ,  C07C255/41 ,  C07C271/16 ,  C07C2601/02 ,  C07D213/57 ,  C07D261/08 ,  C07D307/54 ,  C07D307/81 ,  C07D333/24 ,  C07C49/84

    Abstract: Compounds of formula (I), wherein A1 and A2 are each independently of the other a bond or a C1-C6alkylene bridge; A3 is a C1-C6alkylene bridge; X1 and X2 are each independently of the other fluorine, chlorine or bromine; Y is O, NR7, S, SO or SO2; R1, R2 and R3 are each independently of the others, for example, H, halogen, OH, SH, CN, nitro, C1-C6alkyl, C1-C6haloalkyl, C1-C6alkylcarbonyl or C2-C6alkenyl; Q is O, NR5, S, SO or SO2; W is, for example, O, NR5 or SO; T is for example, a bond, O or NR5; D is CH or N; R4 is, for example, H, halogen, OH, SH, CN or nitro; R5 and R7 are, for example, H, C1-C6alkyl or C1-C3haloalkyl; k is 1, 2, 3 or 4; m is 1 or 2; R10 is a radical which contains 0, N or S; R11 is, for example, H, C1-C12alkyl or a radical which contains from one to three hetero atoms selected from O, N and S; or R11 together with R12 is a bond; R12 is, for example, H, C1-C6alkyl, halo-C1-C6alkyl or C1-C6alkoxy-C1-C6-alkyl; and, where applicable, their possible E/Z isomeric mixtures isomers, EQ isomeric mixtures and/or tautomers, in each case in free from or in salt form, a process for the preparation of those compounds and their use, pesticidal compositions in which the active ingredient has been selected from those compounds or an agrochemically acceptable salt thereof; a process for the preparation of those compositions and their use, plant propagation material treated with those compositions, and a method of controlling pests.

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