Patent search ap:("Abbott Cardiovascular Systems Inc.") AND inv:"Yunbing Wang" Page 2

11.

发明申请
METHODS OF STABILIZING MOLECULAR WEIGHT OF POLYMER STENTS AFTER STERILIZATION 审中-公开
Title translation: 杀菌后稳定聚合物分子量的方法

公开(公告)号：US20150137428A1

公开(公告)日：2015-05-21

申请号：US14597144

申请日：2015-01-14

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Yunbing Wang , Kerek Mortisen , Xiao Ma , Fuh-Wei Tang , Byron Lambert

IPC: A61F2/82

CPC classification number: A61F2/82 , A61F2/0095 , A61F2240/001 , A61L2/081 , A61L2/082 , A61L2/087 , B29C71/009 , B29C71/04 , B29C2035/0877 , B65B55/16

Abstract: Methods of stabilizing the molecular weight of polymer stents scaffolds after E-beam sterilization are disclosed. The molecular weight of the polymer of the irradiated scaffolds is stabilized through exposure to gas containing oxygen.

Abstract translation: 公开了电子束灭菌后稳定聚合物支架支架分子量的方法。照射的支架的聚合物的分子量通过暴露于含氧气体而稳定。

12.

发明申请
CONTROL OF DEGRADATION PROFILE OF BIOABSORBABLE POLY(L-LACTIDE) SCAFFOLD 审中-公开
Title translation: 生物可溶性聚（L-柠檬酸）螯合物的降解特性的控制

公开(公告)号：US20140353877A1

公开(公告)日：2014-12-04

申请号：US14460199

申请日：2014-08-14

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Yunbing Wang , Xiao Ma

IPC: A61L31/14 , B29C35/02 , B29C47/00 , A61L31/06 , B29C35/08

CPC classification number: A61L31/148 , A61L31/06 , A61L2430/00 , A61L2430/22 , B29C35/0288 , B29C35/0805 , B29C48/022 , B29C48/09 , B29C48/92 , B29C2035/0838 , B29C2948/92228 , B29C2948/92704 , B29K2067/046 , B29K2105/0002 , B29K2995/0088 , B29L2023/22 , B29L2031/7532 , C08L67/04

Abstract: Methods of controlling the degradation profile of a biodegradable stent scaffolding are disclosed. Disclosed methods include controlling features of the degradation profile including the time to loss of radial strength and the degradation time of the stent.

Abstract translation: 公开了控制可生物降解的支架支架的降解特征的方法。所公开的方法包括控制降解曲线的特征，包括损失径向强度的时间和支架的降解时间。

13.

发明申请
BIORESORBABLE IMPLANTS FOR TRANSMYOCARDIAL REVASCULARIZATION 审中-公开
Title translation: 用于转移性重建的生物体植入物

公开(公告)号：US20140336747A1

公开(公告)日：2014-11-13

申请号：US14253760

申请日：2014-04-15

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Richard Rapoza , Nadine Ding , Yunbing Wang , Stephen Pacetti , Derek Mortisen

IPC: A61F2/82 , A61L29/16 , A61L29/14

CPC classification number: A61F2/82 , A61L29/146 , A61L29/148 , A61L29/16 , A61L31/146 , A61L31/148 , A61L31/16 , A61L2300/414 , A61L2300/42

Abstract: Implants for treating insufficient blood flow to a heart muscle with transmyocardial revascularization are disclosed. Methods of treating insufficient blood flow to a heart muscle with the implant are also disclosed. The implant can have a body with an inner lumen that supports a channel in the heart muscle to allow for increased blood flow through the lumen upon implantation. The implant can include active agents to prevent or inhibit thrombotic closure of the channel, to promote vascularization, or both.

Abstract translation: 公开了用于治疗心肌血运重建的心肌不足的植入物。还公开了用植入物治疗心肌不足的方法。植入物可以具有内部内腔的主体，其支撑心肌中的通道，以允许在植入时通过内腔增加血流量。植入物可以包括活性剂以预防或抑制通道的血栓闭塞，促进血管形成，或两者。

14.

发明申请
DRUG DELIVERY DEVICE FOR PERIPHERAL ARTERY DISEASE 有权
Title translation: 用于外周动脉疾病的药物递送装置

公开(公告)号：US20140277398A1

公开(公告)日：2014-09-18

申请号：US13802098

申请日：2013-03-13

Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.

Inventor： Yunbing Wang , James Oberhauser , Manish Gada

IPC: A61F2/06

CPC classification number: A61F2/06 , A61L31/041 , A61L31/129 , A61L31/148 , A61L31/16 , A61L2300/422 , C08L67/04

Abstract: A medical device implantable within a peripheral vessel of the body composed of a bioresorbable polymer is disclosed. The device has a high resistance to fracture, is very flexible, and has a high crush recovery when subjected to crushing, axial, or torsional forces.

Abstract translation: 公开了一种可植入在由生物可再吸收的聚合物组成的身体的外周血管内的医疗装置。该装置具有高抗断裂性，非常柔软，并且当受到破碎，轴向或扭转力时具有高的压碎恢复性。

$Biodegradable stent with enhanced fracture toughness$

15.

发明申请
Biodegradable stent with enhanced fracture toughness 审中-公开
Title translation: 具有增强断裂韧性的生物降解支架

公开(公告)号：US20140128959A1

公开(公告)日：2014-05-08

申请号：US13998195

申请日：2013-10-09

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： David C. Gale , Bin Huang , Timothy A. Limon , Vincent J. Gueriguian , Anthony J. Abbate , Klaus Kleine , Stephen Schaible , Jonathan P. Durcan , Thierry Glauser , Bethany Steichen , James Oberhauser , Manish Gada , Lothar Kleiner , Mary Beth Kossuth , Yunbing Wang , Daniel Castro , David Wrolstad

IPC: A61F2/82

CPC classification number: A61F2/915 , A61F2002/91533 , A61F2002/91566 , A61F2210/0004 , A61F2240/001 , A61F2250/0067 , A61L31/06 , A61L31/14 , A61L31/148 , B29C35/045 , B29C49/0005 , B29C49/04 , B29C49/14 , B29C49/4823 , B29C55/24 , B29C2049/0089 , B29C2793/0009 , B29K2067/00 , B29K2067/046 , B29K2105/258 , B29K2995/006 , B29L2031/7534 , C08L67/04

Abstract: Stents and methods of manufacturing a stents with enhanced fracture toughness are disclosed.

Abstract translation: 公开了制造具有增强的断裂韧性的支架的支架和方法。

16.

发明申请
STENT RETAINED ON A BALLOON CATHETER 审中-公开
Title translation: STENT保留在气球导管上

公开(公告)号：US20140052235A1

公开(公告)日：2014-02-20

申请号：US14059382

申请日：2013-10-21

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Yunbing Wang , Gregory Kilinski , Luis Vazquez

IPC: A61F2/958

CPC classification number: A61F2/958 , A61F2002/9522 , B23P11/005 , Y10T29/49865 , Y10T29/49908 , Y10T29/49911 , Y10T29/49913 , Y10T29/49925 , Y10T29/49934

Abstract: A balloon is inflated from a collapsed configuration, then deflated. A polymeric stem is then disposed over the deflated balloon and the stent crimped to the balloon.

Abstract translation: 气球从收缩构型充气，然后放气。然后将聚合物杆设置在放气的气囊上，并且支架卷曲到气囊。

17.

发明申请
STENTS INCLUDING POLY(L-LACTIDE) FORMULATIONS THAT MINIMIZE MOLECULAR WEIGHT DROP DURING PROCESSING 有权
Title translation: 包括在加工过程中最小化分子量降低的聚（L-柠檬酸）配方的方法

公开(公告)号：US20140012365A1

公开(公告)日：2014-01-09

申请号：US14022098

申请日：2013-09-09

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Byron Lambert , Yunbing Wang , James Oberhauser

IPC: A61L31/14 , A61F2/82 , A61L31/04

CPC classification number: B29C47/0076 , A61F2/82 , A61L31/041 , A61L31/06 , A61L31/143 , A61L31/148 , B29D23/20 , B29K2005/00 , B29L2023/20 , B29L2031/753 , C08J3/28 , C08J2367/04 , C08L67/04

Abstract: A stent scaffolding including a polymer formulation comprising PLLA and polymandelide is disclosed. The polymandelide reduces the molecular weight drop during processing, particularly during sterilization. The stent scaffolding can further include one or more additional stabilizing agents that additionally reduce the molecular weight drop during processing.

Abstract translation: 公开了一种包括含有PLLA和聚扁桃酸酯的聚合物制剂的支架支架。聚对苯二甲酸丁二醇酯降低加工过程中的分子量下降，特别是在灭菌过程中。支架支架还可包括一种或多种附加的稳定剂，其另外降低加工过程中的分子量下降。

18.

发明申请
METHOD TO MINIMIZE CHAIN SCISSION AND MONOMER GENERATION IN PROCESSING OF POLY(L-LACTIDE) STENT 有权
Title translation: 减少聚合（L-LACTIDE）STENT处理中的链分离和单体产生的方法

公开(公告)号：US20130300034A1

公开(公告)日：2013-11-14

申请号：US13946964

申请日：2013-07-19

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Yunbing Wang , James OBERHAUSER

IPC: A61L31/06

CPC classification number: A61F2/82 , A61F2/958 , A61F2002/9583 , A61L31/06 , A61L31/148 , H01J2237/31 , C08L67/04

Abstract: Methods of fabricating an implantable medical devices such as stents made from biodegradable polymers are disclosed that reduce or minimize chain scission and monomer generation during processing steps. The method includes processing a poly(L-lactide) resin having an number average molecular weight between 150 to 200 kD in an extruder in a molten state. A poly(L-lactide) tube is formed from the processed resin and a stent is fabricated from the tube. The number average molecular weight of the poly(L-lactide) of the stent after sterilization is 70 to 100 kD.

Abstract translation: 公开了制造可植入医疗装置的方法，例如由可生物降解的聚合物制成的支架，其可减少或最小化加工步骤期间的链断裂和单体产生。该方法包括在熔融状态的挤出机中加工数均分子量为150〜200kD的聚（L-丙交酯）树脂。由处理后的树脂形成聚（L-丙交酯）管，并由管制造支架。灭菌后支架的聚（L-丙交酯）数均分子量为70〜100kD。