公开(公告)号：US20140326672A1

公开(公告)日：2014-11-06

申请号：US14361463

申请日：2012-11-29

Applicant: Agency for Science, Technology and Research

Inventor： Yugen Zhang ,  Mei Xuan Tan ,  Jackie Y. Ying

IPC: B01J20/30 ,  C08G12/32 ,  B01D15/20 ,  B01D15/38 ,  B01J20/28 ,  C02F1/28

CPC classification number: B01J20/3085 ,  B01D15/00 ,  B01D15/203 ,  B01D15/3804 ,  B01J20/262 ,  B01J20/264 ,  B01J20/28057 ,  B01J20/28076 ,  B01J20/28083 ,  B01J20/3425 ,  B01J20/345 ,  C02F1/285 ,  C02F1/683 ,  C02F2101/20 ,  C02F2303/16 ,  C08G12/32

Abstract: Described herein is a melamine-aldehyde polymer, wherein the polymer has a pore volume in the range of about 1.5 to 5 cm3/g.

Abstract translation: 本文描述的是三聚氰胺 - 醛聚合物，其中聚合物的孔体积在约1.5至5cm 3 / g的范围内。

公开(公告)号：US11154054B2

公开(公告)日：2021-10-26

申请号：US16335239

申请日：2017-09-19

Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

Inventor： Yugen Zhang ,  Guangshun Yi

IPC: A01N25/26 ,  A01N59/16 ,  C09D5/14 ,  C09D7/61 ,  A01N59/20 ,  C09D7/40 ,  C09D7/62 ,  B82Y30/00 ,  C08K3/22 ,  C08K3/20

Abstract: The present disclosure relates to an antimicrobial coating on a surface, a method for preparing and uses of the same. In particular it relates to a process for preparing an antimicrobial coating on a surface, the process comprising the steps of: a) providing a surface; b) coating a metal oxide or a metal hydroxide on the surface in the presence of a solvent in a hydrothermal synthesis step to form a coated surface having a plurality of nanostructures; c) optionally drying the coated surface, wherein said nanostructure is preferably in nanopillar structure. The coating of the present application exhibits excellent antimicrobial activity against different types of microorganism, such as bacteria and yeast. The nanostructures are able to exert stress to the microorganism, and therefore controlling or killing them.

公开(公告)号：US20190016684A1

公开(公告)日：2019-01-17

申请号：US16041724

申请日：2018-07-20

Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

Inventor： Yugen Zhang ,  Siti Nurhanna Binti Riduan ,  Yuan Yuan

IPC: C07D233/56 ,  A61K9/06 ,  A61K47/10 ,  A61K9/00 ,  A61Q17/00 ,  A61K8/49 ,  A61K8/04 ,  A01N43/50 ,  A01N25/04 ,  A01N25/10

CPC classification number: C07D233/56 ,  A01N25/04 ,  A01N43/50 ,  A61K8/042 ,  A61K8/4946 ,  A61K9/0014 ,  A61K9/06 ,  A61K47/10 ,  A61Q17/005 ,  A01N25/10

Abstract: The present invention relates to antimicrobial imidazolium compounds having the structure of Formula (I) wherein R is an optionally substituted aliphatic group that is linear, cyclic, saturated, unsaturated or any combination thereof; n is an integer of at least 1; and X is an anionic counterion. The present invention also relates to pharmaceutical composition comprising the compound, a gel comprising the compound, uses of the compound as an antibiotic and methods for the preparation of the gels.

公开(公告)号：US09932454B2

公开(公告)日：2018-04-03

申请号：US15382675

申请日：2016-12-18

Applicant: Agency for Science, Technology and Research

Inventor： Yugen Zhang ,  Jackie Y. Ying ,  Mei Xuan Tan

IPC: B01D53/14 ,  C08J9/28 ,  B01D53/02 ,  B01D53/62 ,  B82Y30/00 ,  B82Y40/00 ,  C08L61/28 ,  C08L61/32 ,  C08G12/32 ,  B01J20/26 ,  B01J20/28 ,  B01J20/30 ,  C08J9/228 ,  C08G101/00

CPC classification number: C08J9/286 ,  B01D53/02 ,  B01D53/62 ,  B01D2253/202 ,  B01D2253/308 ,  B01D2257/502 ,  B01D2257/504 ,  B01J20/262 ,  B01J20/264 ,  B01J20/28007 ,  B01J20/28057 ,  B01J20/28071 ,  B01J20/28073 ,  B01J20/28076 ,  B01J20/2808 ,  B01J20/28083 ,  B01J20/3028 ,  B82Y30/00 ,  B82Y40/00 ,  C08G12/32 ,  C08G2101/00 ,  C08J9/228 ,  C08J2205/044 ,  C08J2361/28 ,  C08L61/28 ,  C08L61/32 ,  Y02C10/04 ,  Y02C10/08 ,  Y02P20/152 ,  Y10T428/2982

Abstract: The present disclosure relates to a polymer material comprising mesopores extending between melamine-formaldehyde co-polymer nano-particles and wherein micropores extend within the co-polymer nano-particles, methods of producing the same and uses thereof.

公开(公告)号：US20160331727A9

公开(公告)日：2016-11-17

申请号：US14789928

申请日：2015-07-01

Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

Inventor： Lang Zhuo ,  Chunyan Zhang ,  Yugen Zhang ,  Jackie Y. Ying ,  Began Gopalan ,  Zhiyuan Ke ,  Zhaobing Ding

IPC: A61K31/4178

CPC classification number: A61K31/4178 ,  A61K31/4184 ,  A61K31/4188 ,  A61K31/439 ,  A61K31/4439 ,  C07D233/58 ,  C07D233/60 ,  C07D233/61 ,  C07D235/06 ,  C07D401/04 ,  C07D401/14 ,  C07D403/04 ,  C07D471/04 ,  C07D487/04 ,  C07D487/22

Abstract: There is presently provided methods for delivering an anti-fibrotic or anti-cancer agent to a cell. The methods comprise contacting a cell with an effective amount of imidazolium and imidazolinium compounds as described herein, including imidazolium and imidazolinium salts.

公开(公告)号：US10167267B2

公开(公告)日：2019-01-01

申请号：US15023668

申请日：2014-09-17

Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

Inventor： Guangshun Yi ,  Yugen Zhang

IPC: C07D307/02 ,  C07D307/68 ,  B01J23/52 ,  C07D307/48 ,  B01J37/03 ,  B01J23/00 ,  B01J23/66 ,  B01J35/00

Abstract: The present invention relates to a method for synthesizing an optionally substituted furoic acid by dehydrating a biomass and oxidizing the optionally substituted furan derived from the dehydration reaction. Water extraction has been incorporated as a step between the dehydration and the oxidation in order to purify the intermediate optionally substituted furan before having it oxidized. Prior to this water extraction, the organic solvent used for dehydration may be separated by evaporation. The provision of the water extraction allows impurities to be separated from the intermediate optionally substituted furan.

公开(公告)号：US10077227B2

公开(公告)日：2018-09-18

申请号：US15541925

申请日：2016-04-15

Applicant: Agency for Science, Technology and Research

Inventor： Yugen Zhang ,  Xiukai Li

IPC: C07C51/25 ,  C07C29/60 ,  B01J23/00 ,  B01J23/28 ,  B01J23/30 ,  B01J37/08 ,  B01J37/00 ,  B01J23/22 ,  C07C57/04

CPC classification number: C07C51/25 ,  B01J23/002 ,  B01J23/22 ,  B01J23/28 ,  B01J23/30 ,  B01J37/0009 ,  B01J37/0063 ,  B01J37/08 ,  B01J2523/00 ,  B01J2523/55 ,  B01J2523/68 ,  B01J2523/69 ,  C07C29/60 ,  C07C51/235 ,  C07C57/04 ,  C07C33/03

Abstract: There is provided a method for synthesizing an alkenoic acid, in particular acrylic acid comprising the step of oxidizing an alkenyl alcohol in the presence of a metal oxide catalyst to form the alkenoic acid. The invention further provides a step of deoxydehydrating a polyol, including glycerol to obtain said alkenyl alcohol including an allyl alcohol.

公开(公告)号：US09802902B2

公开(公告)日：2017-10-31

申请号：US15297906

申请日：2016-10-19

Applicant: Agency for Science, Technology and Research

Inventor： Yugen Zhang ,  Jackie Y. Ying ,  Lihong Liu ,  Hong Wu

IPC: C07D233/61 ,  A61K31/787 ,  A01N43/50

CPC classification number: C07D233/61 ,  A01N43/50 ,  A61K31/787

Abstract: There is provided compound for use in therapy, the compound comprising repeating units of hydrophilic heterocyclic amine monomers that are coupled by hydrophobic linkers selected to confer a therapeutic effect. There is also provided the use of the above compound in the manufacture of a medicament for the treatment of a fungal infection and a method of treating a fungal infection using the above compound.

公开(公告)号：US09586878B2

公开(公告)日：2017-03-07

申请号：US14390757

申请日：2013-04-05

Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

Inventor： Guangshun Yi ,  Yugen Zhang

IPC: C07C29/14 ,  C07C29/132

CPC classification number: C07C29/132 ,  C07C31/18 ,  C07C31/26

Abstract: A method for synthesizing a sugar alcohol comprising the step of hydrolyzing a polysaccharide in the presence of hydrogen ions (H+), an alcoholic reducing agent and a hydrogen transfer catalyst to form the sugar alcohol.

Abstract translation: 一种合成糖醇的方法，包括在氢离子（H +），醇还原剂和氢转移催化剂存在下水解多糖以形成糖醇的步骤。

公开(公告)号：US20160000757A1

公开(公告)日：2016-01-07

申请号：US14789928

申请日：2015-07-01

Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

Inventor： Lang Zhuo ,  Chunyan Zhang ,  Yugen Zhang ,  Jackie Y. Ying ,  Began Gopalan ,  Zhiyuan Ke ,  Zhaobing Ding

IPC: A61K31/4178

CPC classification number: A61K31/4178 ,  A61K31/4184 ,  A61K31/4188 ,  A61K31/439 ,  A61K31/4439 ,  C07D233/58 ,  C07D233/60 ,  C07D233/61 ,  C07D235/06 ,  C07D401/04 ,  C07D401/14 ,  C07D403/04 ,  C07D471/04 ,  C07D487/04 ,  C07D487/22

Abstract: There is presently provided methods for delivering an anti-fibrotic or anti-cancer agent to a cell. The methods comprise contacting a cell with an effective amount of imidazolium and imidazolinium compounds as described herein, including imidazolium and imidazolinium salts.

Abstract translation: 目前提供了将抗纤维化或抗癌剂递送至细胞的方法。 所述方法包括使细胞与本文所述的有效量的咪唑鎓和咪唑啉化合物接触，包括咪唑鎓和咪唑啉鎓盐。