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公开(公告)号：US07548314B2
公开(公告)日：2009-06-16
申请号：US12045386
申请日：2008-03-10
申请人： David E. Altobelli , Larry B. Gray , Derek G. Kane
发明人： David E. Altobelli , Larry B. Gray , Derek G. Kane
IPC分类号： G01N21/00
CPC分类号： G01F13/006 , A61B5/08 , A61M15/0003 , A61M15/0065 , A61M15/009 , A61M2016/0021 , A61M2016/0039 , A61M2205/3306 , A61M2205/3331 , A61M2205/3379 , G01F1/34 , G01N1/2202 , G01N15/02 , G01N15/0205 , G01N15/1456 , G01N21/53 , G01N2001/2223 , G01N2021/4707
摘要： An apparatus comprises a detector, a pressure sensor and a processor. The detector is operable to detect light that is scattered by an aerosol that is associated with a pressure. The pressure sensor is operable to measure the pressure. The processor is coupled to the detector and to the pressure sensor, and is configured to receive at least a signal from the detector and the pressure sensor. The processor is further configured to use the received signals to calculate a volume of the first aerosol, and to output an output signal associated with the calculated volume. The various measurements can be repeated and compared, and the output signal can be a feedback signal for metering subsequent amounts of the aerosol, based on the comparison.
摘要翻译： 一种装置包括检测器，压力传感器和处理器。 检测器可操作以检测由与压力相关联的气溶胶散射的光。 压力传感器可操作以测量压力。 处理器耦合到检测器和压力传感器，并且被配置为从检测器和压力传感器接收至少一个信号。 处理器还被配置为使用接收到的信号来计算第一气溶胶的体积，并输出与计算出的体积相关联的输出信号。 可以重复和比较各种测量，并且基于比较，输出信号可以是用于计量后续量的气溶胶的反馈信号。
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公开(公告)号：US20110029260A1
公开(公告)日：2011-02-03
申请号：US12897100
申请日：2010-10-04
IPC分类号： G01F1/66 , G01F23/296
CPC分类号： A61M15/008 , A61M15/0003 , A61M15/002 , A61M15/0045 , A61M15/0048 , A61M15/0065 , A61M15/0066 , A61M15/0068 , A61M15/0085 , A61M15/009 , A61M2016/0021 , A61M2016/0039 , A61M2202/03 , A61M2205/3306 , A61M2205/3368 , A61M2205/3375 , A61M2205/3379 , A61M2205/50 , A61M2205/52 , B05B12/006 , B05B12/085 , G01F1/007 , G01F17/00 , G01F22/00 , G01F23/14 , G01H3/00 , G10K9/04
摘要： An apparatus for metering the delivery of an aerosol. The apparatus has a variable acoustic source and a microphone, both acoustically coupled to a volume having a fluid region and an air region. The apparatus may also include a processor to determine a volume of the air region based on signals received from the microphone and the variable acoustic source. A fluid valve is coupled to the processor, and is configured to allow an amount of fluid to exit the fluid region associated with the volume of the air region. An atomizer, coupled to the fluid region, is configured to aerosolize at least a portion of the fluid.
摘要翻译： 一种用于计量气溶胶输送的装置。 该装置具有声音耦合到具有流体区域和空气区域的体积的可变声源和麦克风。 该装置还可以包括处理器，用于基于从麦克风和可变声源接收的信号来确定空气区域的体积。 流体阀联接到处理器，并且被配置为允许一定量的流体离开与空气区域的体积相关联的流体区域。 耦合到流体区域的雾化器被配置为使至少一部分流体雾化。
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公开(公告)号：US20080212094A1
公开(公告)日：2008-09-04
申请号：US12045386
申请日：2008-03-10
申请人： David E. Altobelli , Larry B. Gray , Derek G. Kane
发明人： David E. Altobelli , Larry B. Gray , Derek G. Kane
IPC分类号： G01N21/00
CPC分类号： G01F13/006 , A61B5/08 , A61M15/0003 , A61M15/0065 , A61M15/009 , A61M2016/0021 , A61M2016/0039 , A61M2205/3306 , A61M2205/3331 , A61M2205/3379 , G01F1/34 , G01N1/2202 , G01N15/02 , G01N15/0205 , G01N15/1456 , G01N21/53 , G01N2001/2223 , G01N2021/4707
摘要： An apparatus comprises a detector, a pressure sensor and a processor. The detector is operable to detect light that is scattered by an aerosol that is associated with a pressure. The pressure sensor is operable to measure the pressure. The processor is coupled to the detector and to the pressure sensor, and is configured to receive at least a signal from the detector and the pressure sensor. The processor is further configured to use the received signals to calculate a volume of the first aerosol, and to output an output signal associated with the calculated volume. The various measurements can be repeated and compared, and the output signal can be a feedback signal for metering subsequent amounts of the aerosol, based on the comparison.
摘要翻译： 一种装置包括检测器，压力传感器和处理器。 检测器可操作以检测由与压力相关联的气溶胶散射的光。 压力传感器可操作以测量压力。 处理器耦合到检测器和压力传感器，并且被配置为从检测器和压力传感器接收至少一个信号。 处理器还被配置为使用接收到的信号来计算第一气溶胶的体积，并输出与计算出的体积相关联的输出信号。 可以重复和比较各种测量，并且基于比较，输出信号可以是用于计量后续量的气溶胶的反馈信号。
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14.发明授权System, method and device for aiding in the diagnosis of respiratory dysfunction 有权用于辅助诊断呼吸功能障碍的系统，方法和装置公开(公告)号：US08348853B2
公开(公告)日：2013-01-08
申请号：US11347971
申请日：2006-02-06
申请人： David E. Altobelli , Benjamin W. Jones, Jr. , Derek G. Kane , Gregory R. Lanier, Jr. , Paul R. Marquis , Eric M. Soederberg
发明人： David E. Altobelli , Benjamin W. Jones, Jr. , Derek G. Kane , Gregory R. Lanier, Jr. , Paul R. Marquis , Eric M. Soederberg
IPC分类号： A61B5/08
摘要： A system and method for aiding in the diagnosis of a respiratory dysfunction is described. More particularly, a system and method for aiding in the diagnosis of one or more pulmonary embolisms is described. The system and method described herein include a plurality of sensors, a thermal control system, and a controller means coupled to the plurality of sensors and the thermal control system for aiding in the diagnosis of a respiratory dysfunction.
摘要翻译： 描述了一种用于辅助诊断呼吸功能障碍的系统和方法。 更具体地，描述了一种用于帮助诊断一个或多个肺栓塞的系统和方法。 本文所述的系统和方法包括多个传感器，热控制系统和耦合到多个传感器的控制器装置和用于帮助诊断呼吸功能障碍的热控制系统。
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15.发明授权公开(公告)号：US08979788B2
公开(公告)日：2015-03-17
申请号：US13361312
申请日：2012-01-30
CPC分类号： A61M1/3621 , A61M1/1006 , A61M1/1037 , A61M1/106 , A61M1/1062 , A61M1/1086 , A61M1/3666 , A61M1/3667 , A61M2205/127 , Y10T137/86035
摘要： A cardiopulmonary bypass system utilizing membrane-based reciprocating positive displacement blood pumps (“pod pumps”). In one aspect, the pod pumps are constructed to provide reduced shear forces on the blood being pumped. In another aspect blood flow through the pod pumps can be controlled by a controller using information from pressure sensors in the control chamber of the pod pumps. In another aspect, the pod pumps are included on a disposable unit that can be received and held by a receptacle means on a base unit, the base unit also providing pressurized control fluid to the pod pumps on the disposable unit through the receptacle means.
摘要翻译： 一种使用膜式往复式正位移血液泵（“荚式泵”）的体外循环系统。 在一个方面，荚果泵构造成在被泵送的血液上提供减小的剪切力。 在另一方面，通过容器泵的血液流动可以由控制器使用来自荚果泵的控制室中的压力传感器的信息来控制。 在另一方面，所述荚式泵包括在一次性单元中，所述一次性单元可以由基座单元上的容器装置接收和保持，所述基座单元还通过所述容器装置向所述一次性单元上的所述容器泵提供加压控制流体。
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16.发明申请公开(公告)号：US20120130298A1
公开(公告)日：2012-05-24
申请号：US13361312
申请日：2012-01-30
CPC分类号： A61M1/3621 , A61M1/1006 , A61M1/1037 , A61M1/106 , A61M1/1062 , A61M1/1086 , A61M1/3666 , A61M1/3667 , A61M2205/127 , Y10T137/86035
摘要： A cardiopulmonary bypass system utilizing membrane-based reciprocating positive displacement blood pumps (“pod pumps”). In one aspect, the pod pumps are constructed to provide reduced shear forces on the blood being pumped. In another aspect blood flow through the pod pumps can he controlled by a controller using information from pressure sensors in the control chamber of the pod pumps. In another aspect, the pod pumps are included on a disposable unit that can be received and held by a receptacle means on a base unit, the base unit also providing pressurized control fluid to the pod pumps on the disposable unit through the receptacle means.
摘要翻译： 一种使用膜式往复式正位移血液泵（“荚式泵”）的体外循环系统。 在一个方面，荚果泵构造成在被泵送的血液上提供减小的剪切力。 在另一方面，通过荚果泵的血流可以由控制器使用来自荚果泵的控制室中的压力传感器的信息来控制。 在另一方面，所述荚式泵包括在一次性单元中，所述一次性单元可以由基座单元上的容器装置接收和保持，所述基座单元还通过所述容器装置向所述一次性单元上的所述容器泵提供加压控制流体。
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公开(公告)号：US08968232B2
公开(公告)日：2015-03-03
申请号：US13018054
申请日：2011-01-31
申请人： Dean Kamen , Jason A. Demers , David E. Altobelli , Larry B. Gray , N. Christopher Perry , Brian Tracey , James D. Dale , Dirk A. van der Merwe , Kingston Owens
发明人： Dean Kamen , Jason A. Demers , David E. Altobelli , Larry B. Gray , N. Christopher Perry , Brian Tracey , James D. Dale , Dirk A. van der Merwe , Kingston Owens
IPC分类号： A61M37/00 , C02F1/44 , A61M1/00 , A61M1/10 , A61M1/36 , F04B43/06 , F04B43/073 , G01K1/08 , G01K1/16 , G01M3/18 , A61F7/12
CPC分类号： A61M1/106 , A61F7/12 , A61F2007/0069 , A61F2007/126 , A61M1/1006 , A61M1/1012 , A61M1/1037 , A61M1/1062 , A61M1/1086 , A61M1/1087 , A61M1/1096 , A61M1/3626 , A61M1/369 , A61M2205/12 , A61M2205/127 , A61M2205/27 , A61M2205/3334 , A61M2205/3368 , A61M2205/3606 , A61M2205/3653 , A61M2205/502 , F04B43/0054 , F04B43/06 , F04B43/0736 , G01K1/08 , G01K1/16 , G01M3/188
摘要： Embodiments of the present invention relate generally to heat-exchanger systems that can be used to heat or cool a fluid such as blood. Pod pumps that provide low shear and low turbulence may be used in such systems, particularly for systems that pump blood. A certain heat-exchanger system used to heat blood or other fluids may be used to provide whole-body hyperthermic treatments or regional hyperthermic chemotherapy treatments. A disposable unit may be used to separate the fluid path from the fluid control systems. The disposable unit typically includes a heat-exchanger component that is received by a corresponding heat exchanger in a base unit. Fluid pumped through the heat-exchanger component is heated by the heat exchanger.
摘要翻译： 本发明的实施例一般涉及可用于加热或冷却诸如血液的流体的热交换器系统。 可以在这种系统中使用提供低剪切和低湍流的杓式泵，特别是用于泵送血液的系统。 用于加热血液或其他液体的某种热交换器系统可用于提供全身热疗治疗或局部高热化疗治疗。 可以使用一次性单元来将流体路径与流体控制系统分离。 一次性单元通常包括由基本单元中的相应热交换器接收的热交换器部件。 泵送通过热交换器部件的流体被热交换器加热。
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18.发明授权公开(公告)号：US08105265B2
公开(公告)日：2012-01-31
申请号：US12249668
申请日：2008-10-10
IPC分类号： A61M37/00
CPC分类号： A61M1/3621 , A61M1/1006 , A61M1/1037 , A61M1/106 , A61M1/1062 , A61M1/1086 , A61M1/3666 , A61M1/3667 , A61M2205/127 , Y10T137/86035
摘要： A cardiopulmonary bypass system utilizing membrane-based reciprocating positive displacement blood pumps (“pod pumps”). In one aspect, the pod pumps are constructed to provide reduced shear forces on the blood being pumped. In another aspect blood flow through the pod pumps can be controlled by a controller using information from pressure sensors in the control chamber of the pod pumps. In another aspect, the pod pumps are included on a disposable unit that can be received and held by a receptacle means on a base unit, the base unit also providing pressurized control fluid to the pod pumps on the disposable unit through the receptacle means.
摘要翻译： 一种使用膜式往复式正位移血液泵（“荚式泵”）的体外循环系统。 在一个方面，荚果泵构造成在被泵送的血液上提供减小的剪切力。 在另一方面，通过容器泵的血液流动可以由控制器使用来自荚果泵的控制室中的压力传感器的信息来控制。 在另一方面，所述荚式泵包括在一次性单元中，所述一次性单元可以由基座单元上的容器装置接收和保持，所述基座单元还通过所述容器装置向所述一次性单元上的所述容器泵提供加压控制流体。
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公开(公告)号：US20110218600A1
公开(公告)日：2011-09-08
申请号：US13018054
申请日：2011-01-31
申请人： Dean Kamen , Jason A. Demers , David E. Altobelli , Larry B. Gray , N. Christopher Perry , Brian Tracey , James D. Dale , Dirk A. van der Merwe , Kingston Owens
发明人： Dean Kamen , Jason A. Demers , David E. Altobelli , Larry B. Gray , N. Christopher Perry , Brian Tracey , James D. Dale , Dirk A. van der Merwe , Kingston Owens
IPC分类号： A61F7/00
CPC分类号： A61M1/106 , A61F7/12 , A61F2007/0069 , A61F2007/126 , A61M1/1006 , A61M1/1012 , A61M1/1037 , A61M1/1062 , A61M1/1086 , A61M1/1087 , A61M1/1096 , A61M1/3626 , A61M1/369 , A61M2205/12 , A61M2205/127 , A61M2205/27 , A61M2205/3334 , A61M2205/3368 , A61M2205/3606 , A61M2205/3653 , A61M2205/502 , F04B43/0054 , F04B43/06 , F04B43/0736 , G01K1/08 , G01K1/16 , G01M3/188
摘要： Embodiments of the present invention relate generally to heat-exchanger systems that can be used to heat or cool a fluid such as blood. Pod pumps that provide low shear and low turbulence may be used in such systems, particularly for systems that pump blood. A certain heat-exchanger system used to heat blood or other fluids may be used to provide whole-body hyperthermic treatments or regional hyperthermic chemotherapy treatments. A disposable unit may be used to separate the fluid path from the fluid control systems. The disposable unit typically includes a heat-exchanger component that is received by a corresponding heat exchanger in a base unit. Fluid pumped through the heat-exchanger component is heated by the heat exchanger.
摘要翻译： 本发明的实施例一般涉及可用于加热或冷却诸如血液的流体的热交换器系统。 可以在这种系统中使用提供低剪切和低湍流的杓式泵，特别是用于泵送血液的系统。 用于加热血液或其他液体的某种热交换器系统可用于提供全身热疗治疗或局部高热化疗治疗。 可以使用一次性单元来将流体路径与流体控制系统分离。 一次性单元通常包括由基本单元中的相应热交换器接收的热交换器部件。 泵送通过热交换器部件的流体被热交换器加热。
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20.发明申请公开(公告)号：US20090099498A1
公开(公告)日：2009-04-16
申请号：US12249668
申请日：2008-10-10
CPC分类号： A61M1/3621 , A61M1/1006 , A61M1/1037 , A61M1/106 , A61M1/1062 , A61M1/1086 , A61M1/3666 , A61M1/3667 , A61M2205/127 , Y10T137/86035
摘要： A cardiopulmonary bypass system utilizing membrane-based reciprocating positive displacement blood pumps (“pod pumps”). In one aspect, the pod pumps are constructed to provide reduced shear forces on the blood being pumped. In another aspect blood flow through the pod pumps can be controlled by a controller using information from pressure sensors in the control chamber of the pod pumps. In another aspect, the pod pumps are included on a disposable unit that can be received and held by a receptacle means on a base unit, the base unit also providing pressurized control fluid to the pod pumps on the disposable unit through the receptacle means.
摘要翻译： 一种使用膜式往复式正位移血液泵（“荚式泵”）的体外循环系统。 在一个方面，荚果泵构造成在被泵送的血液上提供减小的剪切力。 在另一方面，通过容器泵的血液流动可以由控制器使用来自荚果泵的控制室中的压力传感器的信息来控制。 在另一方面，所述荚式泵包括在一次性单元中，所述一次性单元可以由基座单元上的容器装置接收和保持，所述基座单元还通过所述容器装置向所述一次性单元上的所述容器泵提供加压控制流体。
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