摘要:
The present invention makes availables assays and reagents inhibiting paracrine and/or autocrine signals produced by a hedgehog protein or aberrant activation of a hedgehog signal transduction pathway, e.g., which involve the use of a steroidal alkaloid or other small molecule.
摘要:
An improved multi-layered integrated RF/IF circuit board has been disclosed. The board is fabricated beginning with a center layer of material. In a first preferred embodiment, the center layer is a rigid core material. In a second preferred embodiment, the center layer is a pliable non-conductive material. For every layer added to the upper surface of the stack-up structure of the board, a corresponding layer of the same material is added to the lower surface of the stack-up structure. Thus, during the lamination process, both the upper and lower surfaces are primarily soft, pliable non-conductive material. These non-conductive layers absorb any stresses introduced during the lamination process. Thus, when cooled, the board has large area flatness. Standard manufacturing processes can be used for each individual step in the fabrication of the board. Therefore, a multi-layered integrated RF/IF circuit board in accordance with the present invention can be fabricated inexpensively.
摘要:
A porous medical implant and a method of making same is described. The medical implant comprises a porous surface formed by application of pulsed electrical energy ins such a way as to cause a localized heating in the surface of the material comprising portions of the implant. The method comprises a pulsed current sintering technique.
摘要:
An E-plane waveguide is provided comprising a housing having opposed walls defining a waveguide channel. The waveguide includes at least two elements spaced apart in a direction along the waveguide channel and disposed between and spaced from the opposed walls, and which define a resonant cavity therebetween with the waveguide channel. At least one of the walls has first and second protrusions which are spaced apart in a direction along the waveguide channel and protrude into the waveguide channel. The spacing between the protrusions is less than half a wavelength of the resonant frequency of the resonant cavity.
摘要:
A partial rim implant for an acetabulum in a pelvic bone comprises a ridge, a bearing surface, and a fixation surface. The ridge is oriented to replace a labrum. The bearing surface is configured to align with the articulating surface of the acetabulum. The bearing surface extends from the ridge toward the apex of the acetabulum. The fixation surface is configured to fix the implant to a prepared bone surface of the pelvic bone.
摘要:
A fan drive system is provided having a housing connected with a pulley. A fan shaft is rotatably mounted to the housing by a clutch. A piston actuates the clutch. A pressure tube is provided for delivering pressure to the piston. A valve controls pressure against the piston. A fixed shaft rotatably supports the housing and the pulley and has passages extending through the pulley. A base connects the support shaft to a vehicle structure. An oil plate has inlets and outlets with the shaft passages. The oil plate circulates the hydraulic fluid. A coolant plate is juxtaposed between the oil plate and the structure supporting the support shaft. The coolant plate has inlets and outlets for coolant from a remote cooler.
摘要:
The invention relates to imaging methods and systems. The systems may comprise a white light source configured to generate light in a first wavelength range, an excitation source configured to generate light at one or more wavelengths for exciting a fluorescent substance, a first detector configured to acquire reflectance image data that represents white light reflected from a subject, and a second detector configured to acquire fluorescence image data that represents fluorescence emissions from the subject. At least one of the one or more wavelengths generated by the excitation light source is within the first wavelength range of the white light source. The fluorescent substance may be, for example, a fluorescent dye that is injected into a patient before or during a surgery. The system may also include an image processing engine and a display. The image processing engine may receive the reflectance image data and the fluorescence image data and generate a merged image in which the fluorescence image data is superimposed on the reflectance image data. The display may be used by a surgeon, for example, to more effectively visualize the surgical site during surgery.
摘要:
An electronic advertisement includes an ad layout that defines at least one element, the element referring to media content for the electronic advertisement. The media content including text in vector format, a border that is scalable without loss in fidelity, and logic that enables swapping an image based on a change in display characteristics of the electronic advertisement.
摘要:
An improved multi-layered integrated RF/IF circuit board has been disclosed. The board is fabricated beginning with a center layer of material. In a first preferred embodiment, the center layer is a rigid core material. In a second preferred embodiment, the center layer is a pliable non-conductive material. For every layer added to the upper surface of the stack-up structure of the board, a corresponding layer of the same material is added to the lower surface of the stack-up structure. Thus, during the lamination process, both the upper and lower surfaces are primarily soft, pliable non-conductive material. These non-conductive layers absorb any stresses introduced during the lamination process. Thus, when cooled, the board has large area flatness. Standard manufacturing processes can be used for each individual step in the fabrication of the board. Therefore, a multi-layered integrated RF/IF circuit board in accordance with the present invention can be fabricated inexpensively.
摘要:
The present invention is directed to methods and compositions regarding the preparation of an cell concentrate, such as, for example, an osteogenic cell concentrate, from a physiological solution, such as bone marrow aspirate, blood, or a mixture thereof. In specific embodiments, the invention provides methods and compositions utilizing two physiological solution-processing techniques, particularly in a point of care environment, wherein centrifugation is not employed.