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公开(公告)号：US10655994B2
公开(公告)日：2020-05-19
申请号：US15546327
申请日：2015-04-30
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor： Alexander Govyadinov , Erik D Torniainen , Pavel Kornilovich
Abstract: An apparatus includes a microfluidic channel and a flow sensor along the microfluidic channel. The flow sensor includes a heat emitting resistor for connection to an electric current source, analytical parameter sensor and electronics. The heat emitting resistor has a resistance that varies in response to temperature. The electrical parameter sensor is to sense an electrical parameter of the heat emitting resistor that is based on the resistance of the heat emitting resistor. The electronics determine a flow based on the sensed electrical parameter.
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公开(公告)号：US10415086B2
公开(公告)日：2019-09-17
申请号：US15955364
申请日：2018-04-17
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Pavel Kornilovich , Erik D. Tornianinen , Alexander Govyadinov , David P. Markel
Abstract: In one embodiment, a polymerase chain reaction (PCR) system includes a mixture chamber, a denature chamber, an annealing chamber, an extension chamber, and a product chamber, that are fluidically coupled to one another through a plurality of microfluidic channels. An inertial pump is associated with each microfluidic channel, and each inertial pump includes a fluid actuator integrated asymmetrically within its associated microfluidic channel. The fluid actuators are capable of selective activation to circulate fluid between the chambers in a controlled cycle.
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公开(公告)号：US10286366B2
公开(公告)日：2019-05-14
申请号：US14407005
申请日：2012-09-24
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Alexander Govyadinov , Erik D. Torniainen , David P. Markel , Pavel Kornilovich
Abstract: In one embodiment, a microfluidic mixing device includes a mixing channel, a fluid inlet chamber to pass fluids into the mixing channel, an axis-asymmetric mixing actuator integrated within the channel to cause fluid displacements that mix the fluids as they flow through the channel, and an outlet chamber to receive the mixed fluids.
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公开(公告)号：US20180264753A1
公开(公告)日：2018-09-20
申请号：US15763167
申请日：2016-01-29
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Pavel Kornilovich , Vladek Kasperchik , Michael G. Monroe
IPC: B29C67/24 , B29C64/165 , C08K3/013 , C08K7/28
Abstract: A three-dimensional (3D) printing composite build material composition includes a polymer particle and an inorganic particle. The polymer particle is an aliphatic polyamide. The inorganic particle has an average particle size ranging from about 1 μm to about 100 μm. A mass ratio of the polymer particle to the inorganic particle in the composite build material composition ranges from about 5:2 to about 1:3.
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公开(公告)号：US20150190767A1
公开(公告)日：2015-07-09
申请号：US14407005
申请日：2012-09-24
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Alexander Govyadinov , Erik D. Torniainen , David P. Markel , Pavel Kornilovich
CPC classification number: B01F5/12 , B01F11/0071 , B01F13/0059 , B01F15/00493 , B01L3/50273 , B01L2300/0867 , B01L2300/0883 , B01L2400/0433 , B01L2400/0442 , B01L2400/0487
Abstract: In one embodiment, a microfluidic mixing device includes a mixing channel, a fluid inlet chamber to pass fluids into the mixing channel, an axis-asymmetric mixing actuator integrated within the channel to cause fluid displacements that mix the fluids as they flow through the channel, and an outlet chamber to receive the mixed fluids.
Abstract translation: 在一个实施例中，微流体混合装置包括混合通道，用于将流体输送到混合通道中的流体入口室，集成在通道内的轴对称混合致动器，以引起当流体流过通道时混合流体的流体位移， 以及用于接收混合流体的出口室。
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Patent Agency Ranking
公开(公告)号：US12071657B2
公开(公告)日：2024-08-27
申请号：US16643054
申请日：2017-10-20
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Adam Higgins , Pavel Kornilovich , Alexander N. Govyadinov , Michael J. Day
IPC: B01L3/00 , B01L7/00 , B01L99/00 , C12Q1/6806 , C12Q1/686
CPC classification number: C12Q1/686 , B01L3/502746 , B01L7/525 , C12Q1/6806 , B01L2300/0816 , B01L2300/0867 , B01L2300/0883 , B01L2400/0688 , B01L2400/0694
Abstract: A nucleic acid amplifier may include a sample preparation zone, a fluid ejector, an amplification zone and a capillary break between the amplification zone and the fluid ejector.
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公开(公告)号：US11865540B2
公开(公告)日：2024-01-09
申请号：US16317429
申请日：2016-09-23
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Pavel Kornilovich , Alexander N. Govyadinov
IPC: G01N33/68 , G01N21/33 , G01N21/64 , G01N33/52 , C07C309/05 , C07C309/73 , A01N1/02 , G01N1/40 , B01L3/00
CPC classification number: B01L3/50273 , B01L3/502738 , B01L3/502746 , B01L2200/0605 , B01L2200/0621 , B01L2300/0861 , B01L2300/0867 , B01L2400/0433 , B01L2400/0442
Abstract: A microfluidic device may include at least four interconnected microfluidic channels and a set of fluid actuators. The set of fluid actuators may include a fluid actuator asymmetrically located within at least two of the at least four interconnected microfluidic channels. Each of the at least four interconnected microfluidic channels may be activated to a fluid inputting state, a fluid outputting state and a fluid blocking state in response to selective actuation of different combinations of fluid actuators of the set.
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公开(公告)号：US11686327B2
公开(公告)日：2023-06-27
申请号：US16493344
申请日：2017-04-07
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Erik D. Torniainen , Alexander Govyadinov , Pavel Kornilovich , David P. Markel
CPC classification number: F04F7/00 , B01L3/50273 , B01L3/502738 , B81B1/006 , F04B53/10 , B01L2200/141 , B01L2200/16 , B01L2400/0605 , B81B2201/051 , B81B2203/0338
Abstract: The present disclosure is drawn to inertial pumps. An inertial pump can include a microfluidic channel, a fluid actuator located in the microfluidic channel, and a check valve located in the microfluidic channel. The check valve can include a moveable valve element, a narrowed channel segment located upstream of the moveable valve element, and a blocking element formed in the microfluidic channel downstream of the moveable valve element. The narrowed channel segment can have a width less than a width of the moveable valve element so that the moveable valve element can block fluid flow through the check valve when the moveable valve element is positioned in the narrowed channel segment. The blocking element can be configured such that the blocking element constrains the moveable valve element within the check valve while also allowing fluid flow when the moveable valve element is positioned against the blocking element.
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公开(公告)号：US11097270B2
公开(公告)日：2021-08-24
申请号：US16300115
申请日：2016-07-15
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor： Pavel Kornilovich , Alexander Govyadinov , David P. Markel , Erik D. Torniainen
Abstract: A microfluidic filtering system may include a first microfluidic channel, a first pump to move fluid along the first microfluidic channel in a first direction, a second microfluidic channel, a second pump to move fluid along the second microfluidic channel in a second direction opposite to the first direction and a filter channel extending between and interconnecting the first microfluidic channel and the second microfluidic channel.
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公开(公告)号：US10913039B2
公开(公告)日：2021-02-09
申请号：US16300975
申请日：2016-07-06
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor： Alexander Govyadinov , Pavel Kornilovich , Erik D. Torniainen , David P. Markel
Abstract: One example provides a microfluidic mixing device that includes a main fluidic channel to provide main fluidic channel flow and a number of I-shaped secondary channels extending outwardly from a portion of the main fluidic channel. A number of inertial pumps are located within the I-shaped secondary channels to create serpentine flows in the direction of the main fluidic channel flow or create vorticity-inducing counterflow in the main fluidic channel.
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