摘要:
Implantable medical devices that include cathodic arc produced structures are provided. Cathodic arc produced structures of the invention may be thick, stress-free metallic structures that have configurations heretofore not available in implantable medical devices. In yet other embodiments, the structures may be crenulated or porous layers. Also provided are methods of producing implantable medical devices as well as systems for practicing the subject methods.
摘要:
Implantable hermetically sealed structures and methods for making the same are provided. Also provided are devices, systems and kits including the hermetically sealed structures, as well as methods of using such devices and systems.
摘要:
The hybrid cool roof has a near horizontal solar reflecting surface, and a second esthetic surface, which is angled to the street view. The esthetic surface gives the hybrid cool roof the appearance of a conventional roof when viewed from street level, giving the roof a decorative appearance while having the cooling cost functionality of a conventional cool roof. At times when the sun angle is low in the sky, such as wintertime, the hybrid cool roof is able to absorb solar radiation, lowering heating costs. Thus, the hybrid cool roof has an ideal combination of the function and appearance of conventional cool roofs and traditional roofs, while mitigating the disadvantages of both.
摘要:
Methods for evaluating motion of a cardiac tissue location, e.g., heart wall, are provided. In the subject methods, timing of a signal obtain from a strain gauge stably associated with the tissue location of interest is employed to evaluate movement of the cardiac tissue location. Also provided are systems, devices and related compositions for practicing the subject methods. The subject methods and devices find use in a variety of different applications, including cardiac resynchronization therapy.
摘要:
An ingestible therapy activator system and method are provided. In one aspect, the ingestible therapy activator includes an ingestible device having an effector module to send an effector instruction and a responder module associated with a therapeutic device. The responder module may receive and process the effector instruction, resulting in a response by the therapeutic device. Examples of responses by therapeutic device include activating a therapy, deactivating a therapy, modulating a therapy, and discontinuing a therapy.
摘要:
Methods, devices and systems for acquiring information useful to support a patient in implementing and adhering to a medically prescribed therapy plan are provided. The therapy may incorporate biofeedback methods and/or personalized therapy aspects. A method includes steps of receiving, by a receiving device, biometric information associated with an ingestible event marker; analyzing, by a computing device having a microprocessor configured to perform a biometric information analysis, the biometric information; and determining a therapeutic recommendation at least partly on the basis of the analysis and/or integrating biofeedback techniques into patient therapy or activity. A system includes a biometric information module to receive biometric information associated with an ingestible event marker; an analysis module to analyze the biometric information; and a determination module to optionally determine and communicate a therapeutic recommendation at least partly on the basis of the analysis.
摘要:
Medical carriers that include a low-impedance conductor are provided. The low-impedance conductors are configured to provide electrical conductivity along a length of the medical carrier. An aspect of the low-impedance conductors is the presence of a longitudinally extended region configured as a non-coiled repetitive pattern that imparts fatigue resistance to the longitudinally extended region. Also provided are systems and methods of making the medical carriers, as well as methods of using the medical carriers.
摘要:
Methods of highly selective cardiac tissue stimulation and devices for practicing the same, e.g., implantable segmented electrode devices, are provided. The methods and devices provide a previously unavailable high phrenic nerve capture voltage paired with a low pacing capture voltage threshold. The subject methods and devices provide a number of benefits. For example, patients who previously would have been required to have their resynchronization device turned off due to phrenic nerve capture will now be able to reap the benefits of resynchronization therapy.
摘要:
A mapping and ablating catheter having a short distal tip electrode comprising a bio-compatible outer surface and a thermal dissipating mass for dissipating heat received by the electrode. The outer surface may be formed by plating a thin layer of gold or platinum on the dissipating mass, or the entire electrode may be formed of a homogenous material such as a gold alloy that is bio-compatible thereby forming the outer surface with the mass itself. An alloy having a thermal conductivity greater than pure platinum is used so that the ablation procedure can be completed before exceeding the temperature limits. In one case, the entire electrode was formed of a 88% gold 12% nickel alloy. The electrical feed to the electrode is oversized to also dissipate heat received by the electrode. The electrode is no greater than five mm in length yet produces an ablation volume equal to or greater than longer electrodes. One or more band electrodes may also include thermal dissipating masses.
摘要:
Apparatuses and methods for hybrid housings as well as hybrid housing based implantable medical devices are provided. A hybrid housing comprises a ceramic substrate, a bonding structure formed on the periphery of the ceramic substrate, and a biocompatible metal cap coupled to the ceramic substrate using the bonding structure to form a hermetically sealed enclosure. One or more electronic elements may be formed within the hermetically sealed enclosure, and the electronic elements may be stably associated with the ceramic substrate.