Pharmaceutical composition and method for regenerating myofibers in the treatment of muscle injuries
    11.
    发明授权
    Pharmaceutical composition and method for regenerating myofibers in the treatment of muscle injuries 有权
    用于再生肌纤维治疗肌肉损伤的药物组合物和方法

    公开(公告)号:US09155744B2

    公开(公告)日:2015-10-13

    申请号:US11722915

    申请日:2006-10-27

    摘要: A pharmaceutical composition and method for regenerating cardiomyocytes in treating or repairing heart muscle damages or injuries caused by an ischemic disease. The pharmaceutical composition contains an active ingredient compound with a backbone structure of Formula (I). The active ingredient compound is capable of (a) increasing viability of myogenic precursor cells to enable said precursor cells to survive through an absolute ischemic period; (b) reconstituting a damaged blood supply network in said heart region where said injured muscle is located; and (c) enhancing cardiomyogenic differentiation efficiency of said precursor cells down cardiac linage, said steps being performed simultaneously or in any particular order.

    摘要翻译: 用于再生心肌细胞治疗或修复由缺血性疾病引起的心肌损伤或损伤的药物组合物和方法。 药物组合物含有具有式(I)的骨架结构的活性成分化合物。 活性成分化合物能够(a)增加肌原性前体细胞的活力,使所述前体细胞能够通过绝对缺血期生存; (b)在所述受伤的肌肉位于的所述心脏区域中重建损伤的血液供应网络; 和(c)提高所述前体细胞向下心肌的心肌分化效率,所述步骤同时进行或以任何特定的顺序进行。

    Method and device for processing information given idle-mode signaling reduction
    12.
    发明授权
    Method and device for processing information given idle-mode signaling reduction 有权
    处理信息给空闲模式信令减少的方法和设备

    公开(公告)号:US09155126B2

    公开(公告)日:2015-10-06

    申请号:US13280907

    申请日:2011-10-25

    摘要: A method for processing information given idle-mode signaling reduction (ISR) is disclosed. A serving gateway receives an information update request containing information of related to a current access network where a user equipment is located if the user equipment moves from another access network to the current access network which the user equipment has been registered. The serving gateway updates relating information of the current access network and keeps relating information of the another access networks unchanged if the information update request includes indication information of idle-mode signaling reduction activation.

    摘要翻译: 公开了一种用于处理给出空闲模式信令减少(ISR)的信息的方法。 如果用户设备从另一个接入网络移动到用户设备已被注册的当前接入网络,则服务网关接收到包含与用户设备所在的当前接入网络有关的信息的信息更新请求。 如果信息更新请求包括空闲模式信令减少激活的指示信息,则服务网关更新当前接入网络的相关信息并保持另一接入网络的相关信息不变。

    Deposition of thin film dielectrics and light emitting nano-layer structures
    13.
    发明授权
    Deposition of thin film dielectrics and light emitting nano-layer structures 有权
    沉积薄膜电介质和发光纳米层结构

    公开(公告)号:US09064693B2

    公开(公告)日:2015-06-23

    申请号:US13581281

    申请日:2010-03-01

    摘要: Deposition of thin film dielectrics, and in particular for chemical vapor deposition of nano-layer structures comprising multiple layers of dielectrics, such as, silicon dioxide, silicon nitride, silicon oxynitride, and/or other silicon compatible dielectrics includes post-deposition surface treatment of deposited layers with a metal or semiconductor source gas, e.g., a silicon source gas. Deposition of silicon containing dielectrics comprises silane-based chemistry for deposition of doped or undoped dielectric layers, and surface treatment of deposited dielectric layers with silane. Surface treatment provides dielectric layers with improved layer-to-layer uniformity and lateral continuity, and substantially atomically flat dielectric layers suitable for multilayer structures for electroluminescent light emitting structures, e.g., active layers containing rare earth containing luminescent centers. Doped or undoped dielectric thin films or nano-layer dielectric structures may also be provided for other semiconductor devices.

    摘要翻译: 薄膜电介质的沉积,特别是用于化学气相沉积的包括多层电介质的纳米层结构,例如二氧化硅,氮化硅,氮氧化硅和/或其它与硅相容的电介质包括后沉积表面处理 具有金属或半导体源气体的沉积层,例如硅源气体。 含硅电介质的沉积包括用于沉积掺杂或未掺杂电介质层的硅烷基化学,以及用硅烷表面处理沉积的介电层。 表面处理提供具有改进的层间均匀性和横向连续性的电介质层,以及适用于电致发光发光结构的多层结构的基本上原子平坦的介电层,例如含有含稀土含有发光中心的活性层。 也可以为其它半导体器件提供掺杂或未掺杂的电介质薄膜或纳米层介电结构。

    Insulin formulations for rapid uptake
    14.
    发明授权
    Insulin formulations for rapid uptake 有权
    胰岛素配方快速吸收

    公开(公告)号:US09060927B2

    公开(公告)日:2015-06-23

    申请号:US12397219

    申请日:2009-03-03

    摘要: Injectable insulin formulations with improved stability and rapid onset of action are described herein. The formulations may be for subcutaneous, intradermal or intramuscular administration. In the preferred embodiment, the formulations are administered via subcutaneous injection. The formulations contain insulin in combination with a chelator and dissolution agent, and optionally additional excipients. In the preferred embodiment, the formulation contains human insulin, a zinc chelator such as EDTA and a dissolution agent such as citric acid or sodium citrate. These formulations are rapidly absorbed into the blood stream when administered by subcutaneous injection. In the preferred embodiment, the insulin is provided as a clear liquid, neutral pH, in a multi-use sterile vial. In an alternative embodiment, the insulin is provided as a powder in a sterile vial. This is mixed with a diluent containing a pharmaceutically acceptable carrier, such as water, a zinc chelator such as EDTA and a dissolution agent such as citric acid shortly before or at the time of administration. In another embodiment, the insulin is stored as a frozen mixture, ready for use upon thawing.

    摘要翻译: 本文描述了具有改善的稳定性和快速起效的可注射的胰岛素制剂。 制剂可用于皮下,皮内或肌内给药。 在优选的实施方案中,通过皮下注射施用制剂。 制剂含有与螯合剂和溶解剂以及任选的其它赋形剂组合的胰岛素。 在优选的实施方案中,制剂含有人胰岛素,锌螯合剂如EDTA和溶解剂如柠檬酸或柠檬酸钠。 当通过皮下注射给药时,这些制剂被快速地吸收到血流中。 在优选的实施方案中,胰岛素以多用途无菌小瓶中的透明液体中性pH提供。 在替代实施方案中,胰岛素以无菌小瓶中的粉末形式提供。 将其与包含药学上可接受的载体如水,锌螯合剂如EDTA的稀释剂和不久之前或给药时的溶解剂如柠檬酸混合。 在另一个实施方案中,将胰岛素作为冷冻混合物储存,准备在解冻时使用。

    Method and system for setting up a bearer
    16.
    发明授权
    Method and system for setting up a bearer 有权
    建立承载的方法和系统

    公开(公告)号:US08989116B2

    公开(公告)日:2015-03-24

    申请号:US13558691

    申请日:2012-07-26

    IPC分类号: H04W4/00 H04W76/02 H04L12/66

    摘要: Method and system for setting up a bearer are disclosed. The bearer setup method includes these steps: a packet data network gateway (PGW) obtains first quality of service (QoS) information and a first bearer identifier (ID), and sets up a bearer between the PGW and a radio access network (RAN) according to the first QoS information, where the bearer is associated with the first bearer ID; the RAN sets up a radio bearer (RB) with a user equipment (UE) according to second QoS information associated with the first QoS information, where the RB is associated with a second bearer ID associated with the first bearer ID.

    摘要翻译: 公开了建立承载的方法和系统。 承载建立方法包括以下步骤:分组数据网络网关(PGW)获得第一服务质量(QoS)信息和第一承载标识符(ID),并且在PGW和无线接入网络(RAN)之间建立承载, 根据第一QoS信息,其中承载与第一承载ID相关联; RAN根据与第一QoS信息相关联的第二QoS信息与用户设备(UE)建立无线承载(RB),其中RB与与第一承载ID相关联的第二承载ID相关联。

    Caspofungin analog and applications thereof
    17.
    发明授权
    Caspofungin analog and applications thereof 有权
    卡泊芬净类似物及其应用

    公开(公告)号:US08969513B2

    公开(公告)日:2015-03-03

    申请号:US13884750

    申请日:2011-11-10

    IPC分类号: C07K7/56 A61K38/12 A61K38/00

    CPC分类号: C07K7/56 A61K38/00 A61K38/12

    摘要: Disclosed are a caspofungin analog and applications thereof. The caspofungin analog is a compound having a structure as indicated in Formula (4), or pharmaceutically acceptable salts thereof. R1 can be chosen from hydroxyl, benzyloxy, phenoxy, substituted phenoxy, or substituted benzyloxy. R2, R3, R4, R5 can be chosen from hydrogen, C1-C6 alkyl, C1-C6 alkoxy, hydroxyl, benzyloxyphenyl, substituted benzyloxyphenyl, nitro, fluorine, chlorine, bromine, or iodine. Also disclosed are a preparation method for and applications of the compound.

    摘要翻译: 公开了卡泊芬净类似物及其应用。 卡泊芬净类似物是具有式(4)所示结构的化合物或其药学上可接受的盐。 R 1可以选自羟基,苄氧基,苯氧基,取代的苯氧基或取代的苄氧基。 R2,R3,R4,R5可以选自氢,C1-C6烷基,C1-C6烷氧基,羟基,苄氧基苯基,取代的苄氧基苯基,硝基,氟,氯,溴或碘。 还公开了该化合物的制备方法和应用。

    Method and Device for Setting Properties
    19.
    发明申请
    Method and Device for Setting Properties 审中-公开
    用于设置属性的方法和设备

    公开(公告)号:US20150058874A1

    公开(公告)日:2015-02-26

    申请号:US14389472

    申请日:2012-05-31

    摘要: The disclosure provides a method and a device for setting properties. The method comprises: analyzing and counting one or more program sources selected by a user through an Internet Protocol Television (IPTV) program system; determining program IDs corresponding to the program sources selected by the user according to a analysis and statistics result to acquire the merchandise corresponding to the program IDs in the IPTV merchandise system; and setting the properties of the merchandise, wherein the merchandise properties set are used for indicating how to display the merchandise in the IPTV merchandise system. The problem caused by the identical merchandise recommended to all the users in the IPTV online shopping system in the related art is solved, consequently, personalized services are implemented for different users and the user experience is improved.

    摘要翻译: 本公开提供了一种用于设置属性的方法和装置。 该方法包括:通过互联网协议电视(IPTV)程序系统分析和计数由用户选择的一个或多个节目源; 根据分析统计结果确定与用户选择的节目源相对应的节目ID,以获取与IPTV商品系统中的节目ID相对应的商品; 以及设置商品的属性,其中所述商品属性集用于指示如何在IPTV商品系统中显示商品。 解决了相关技术中IPTV网络购物系统中推荐给所有用户的相同商品造成的问题,为不同用户实现个性化服务,提高用户体验。

    Method and apparatus for fabricating a light-emitting diode package
    20.
    发明授权
    Method and apparatus for fabricating a light-emitting diode package 有权
    用于制造发光二极管封装的方法和装置

    公开(公告)号:US08956892B2

    公开(公告)日:2015-02-17

    申请号:US13347388

    申请日:2012-01-10

    IPC分类号: H01L33/50

    摘要: Disclosed is a method of fabricating a light-emitting diode package, which comprises a light-emitting chip operative to emit light of a first wavelength range. The method comprises the steps of: dispensing a photoluminescent mixture on the light-emitting chip, the photoluminescent mixture being capable of absorbing a portion of light of the first wavelength range emitted from the light-emitting chip to re-emit light of a second wavelength range; partially curing the photoluminescent mixture by heating the photoluminescent mixture to a pre-curing temperature and then cooling the photoluminescent mixture to below the pre-curing temperature; and fully curing the photoluminescent mixture to harden the photoluminescent mixture. An apparatus for fabricating a light-emitting diode package is also disclosed.

    摘要翻译: 公开了一种制造发光二极管封装的方法,其包括可发射第一波长范围的光的发光芯片。 该方法包括以下步骤:在发光芯片上分配光致发光混合物,所述光致发光混合物能够吸收从发光芯片发射的第一波长范围的一部分光,以重新发射第二波长的光 范围; 通过将光致发光混合物加热至预固化温度,然后将光致发光混合物冷却至预固化温度以下来部分固化光致发光混合物; 并充分固化光致发光混合物以硬化光致发光混合物。 还公开了一种用于制造发光二极管封装的装置。