Indoles as naaladase inhibitors
    12.
    发明申请
    Indoles as naaladase inhibitors 失效
    吲哚作为纳拉肽酶抑制剂

    公开(公告)号:US20050080128A1

    公开(公告)日:2005-04-14

    申请号:US10500319

    申请日:2002-12-19

    CPC分类号: C07D209/42

    摘要: This invention relates to new compounds, pharmaceutical compositions and diagnostic kits comprising such compounds, and methods of using such compounds for inhibiting NAALADase enzyme activity, detecting diseases where NAALAdase levels are altered, effecting neuronal activity, effecting TGF-β activity, inhibiting angiogenesis, and treating glutamate abnormalities, neuropathy, pain, compulsive disorders, prostate diseases, cancers and glaucoma.

    摘要翻译: 本发明涉及包含这些化合物的新化合物,药物组合物和诊断试剂盒,以及使用这些化合物抑制NAALADase酶活性的方法,检测NAALAdase水平被改变,影响神经元活性,影响TGF-β活性,抑制血管发生的疾病,以及 治疗谷氨酸异常,神经病,疼痛,强迫症,前列腺疾病,癌症和青光眼。

    Thiol-based NAALADase inhibitors
    13.
    发明授权
    Thiol-based NAALADase inhibitors 失效
    基于硫醇的NAALADase抑制剂

    公开(公告)号:US06586623B2

    公开(公告)日:2003-07-01

    申请号:US10046917

    申请日:2002-01-17

    IPC分类号: C07C32106

    摘要: This invention relates to new compounds, pharmaceutical compositions and diagnostic kits comprising such compounds, and methods of using such compounds for inhibiting NAALADase enzyme activity, detecting diseases where NAALADase levels are altered, effecting neuronal activity, effecting TGF-&bgr; activity, inhibiting angiogenesis, and treating glutamate abnormalities, diabetic neuropathy, pain, compulsive disorders, prostate diseases, cancers and glaucoma.

    摘要翻译: 本发明涉及包含这些化合物的新化合物,药物组合物和诊断试剂盒,以及使用这些化合物抑制NAALADase酶活性的方法,检测NAALADase水平改变,影响神经元活性,影响TGF-β活性,抑制血管生成的疾病,以及 治疗谷氨酸异常,糖尿病性神经病,疼痛,强迫症,前列腺疾病,癌症和青光眼。

    Liquid fuel for combustion appliances and combustion appliance using the
same
    14.
    发明授权
    Liquid fuel for combustion appliances and combustion appliance using the same 失效
    用于燃烧器具的液体燃料和使用其的燃烧器具

    公开(公告)号:US6120566A

    公开(公告)日:2000-09-19

    申请号:US68433

    申请日:1998-07-23

    IPC分类号: C10L1/00 C10L1/02 F23D3/24

    CPC分类号: C10L1/003 C10L1/02

    摘要: A liquid fuel for combustion appliances, in which a combustion wick for sucking up the fuel by the utilization of capillarity is used, contains an alcohol as a principal constituent and contains a hydrocarbon compound, which has approximately the same boiling point as that of the principal constituent, as a flame reaction agent. By the addition of the flame reaction agent, which is not accompanied by the occurrence of clogging of the combustion wick, the combustion flame of an alcohol, which otherwise produces a colorless flame, is colored and its visual perceptibility is thereby enhanced, such that the structure of the combustion appliance may be kept simple and the flame stability may be obtained reliably.

    摘要翻译: PCT No.PCT / JP97 / 03119 Sec。 371日期:1998年7月23日 102(e)日期1998年7月23日PCT 1997年9月5日PCT公布。 公开号WO98 / 11176 日期1998年3月19日使用燃烧器具的液体燃料,其中使用通过利用毛细管作用吸收燃料的燃烧芯,其包含醇作为主要成分并且含有具有大致相同沸点的烃化合物 作为主要成分,作为火焰反应剂。 通过添加不伴随燃烧芯堵塞的火焰反应剂,否则产生无色火焰的醇的燃烧火焰被着色,从而增强其视觉感知性,使得 燃烧器具的结构可以保持简单,并且可以可靠地获得火焰稳定性。

    Low pressure CVD system
    16.
    发明授权
    Low pressure CVD system 失效
    低压CVD系统

    公开(公告)号:US5902406A

    公开(公告)日:1999-05-11

    申请号:US818096

    申请日:1997-03-14

    IPC分类号: C23C16/44 C30B25/08 C23C16/00

    CPC分类号: C23C16/44 C30B25/08

    摘要: A low pressure CVD system comprising an inner tube having an upper end and a lower end opened, and made of a silicon carbide material, an outer tube including a circumferential wall surrounding an outer periphery of the inner tube with a predetermined spacing, an upper wall closing an upper end of the circumferential wall and a flange provided at a lower portion thereof, the outer tube having a lower end opened, a base portion for supporting the inner tube and the outer tube at the lower ends thereof, and for providing hermetic sealing between the lower end of the outer tube and the base portion, the base portion having a central portion formed with an opening, a lid provided for opening and shutting the opening in the base portion, and a furnace wall surrounding the circumferential wall and the upper wall of the outer tube, the furnace wall having a heater arranged on an inner side thereof wherein the outer tube is made of a silicon carbide material, and padding of a silicon carbide material is formed at a corner of a joined portion between the circumferential wall and the flange of the outer tube.

    摘要翻译: 一种低压CVD系统,包括具有上端和下端打开并由碳化硅材料制成的内管,外管包括以预定间隔围绕内管的外周的周壁,上壁 闭合周壁的上端和设置在其下部的凸缘,外管的下端开口,用于在其下端支撑内管和外管的基部,并且用于提供气密密封 在所述外管的下端和所述基部之间,所述基部具有形成有开口的中心部,设置用于打开和关闭所述基部的开口的盖以及围绕所述周壁和所述上部的壁的炉壁 所述炉壁具有设置在其内侧的加热器,其中所述外管由碳化硅材料制成,并且填充碳化硅m 在周壁和外管的凸缘之间的接合部分的角部处形成有空隙。

    Steel wire for making high strength steel wire product and method for
manufacturing thereof
    18.
    发明授权
    Steel wire for making high strength steel wire product and method for manufacturing thereof 失效
    制造高强度钢丝产品的钢丝及其制造方法

    公开(公告)号:US5458699A

    公开(公告)日:1995-10-17

    申请号:US240369

    申请日:1994-05-10

    摘要: A steel wire for making a high strength steel wire product which contains 0.6-1.1% C, 0.2-0.6% Si, 0.3-0.8% Mn, and impurities of max 0.010% P, max 0.010% S, max 0.003% O(oxygen), and max 0.002% N, and has a structure in which the maximum pearlite block size is 4.0 .mu.m, the maximum separation distance in pearlite lamellars is 0.1 .mu.m, and the maximum content of free ferrite is 1% by volume.The steel wire can be manufactured in the process as follows;1 heating a steel wire rod having above-mentioned chemical composition to the austenite range above Ac.sub.3 point or A.sub.cm point,2 initiating plastic deformation to not less than 20% total reduction in cross-sectional area in the temperature range 850.degree. C. -750.degree. C.,3 finishing plastic deformation in the range below Ae.sub.1 point and above 650.degree. C., and4 continuously cooling to a range lower than 650.degree. C. and higher than 550.degree. C., and thus transforming into pearlite phase.

    摘要翻译: 一种用于制造高强度钢丝产品的钢丝,其含有0.6-1.1%C,0.2-0.6%Si,0.3-0.8%Mn和最大0.010%P,最大0.010%S,最大0.003%O(氧气 )和最大0.002%N,并且具有最大珠光体块大小为4.0μm的结构,珠光体层的最大分离距离为0.1μm,游离铁素体的最大含量为1体积%。 钢丝绳可按如下方法制造: + E,crc / 1 /加热具有上述化学成分的钢丝杆,奥氏体范围高于Ac3点或Acm点,+ E,crc / 2 /起始塑性变形至不低于20% 截面积在850℃-750℃,+ E,crc / 3 /整理塑性变形范围在低于Ae1点和650℃以上,+ E,crc / 4 /连续冷却至 范围低于650℃,高于550℃,从而转化成珠光体相。

    Process for manufacturing steel wires for use in wire drawing
    19.
    发明授权
    Process for manufacturing steel wires for use in wire drawing 失效
    制造钢丝用于电线图的方法

    公开(公告)号:US5156692A

    公开(公告)日:1992-10-20

    申请号:US768635

    申请日:1991-10-09

    申请人: Takashi Tsukamoto

    发明人: Takashi Tsukamoto

    IPC分类号: C21D8/06

    CPC分类号: C21D8/06

    摘要: A wire of a high-carbon steel having a carbon content of 0.7%-0.9% by weight is heat-treated so as to form supercooled austenitic phases, then subjected to plastic deformation with a reduction rate of at least 20% in the temperature range of below the Ae.sub.1 point and above 500.degree. C., and transformed into pearlite without heating to the austenitic range.The resulting pearlite has a pearlite block size of not greater than 5.0 .mu.m. Steel filaments which have a tensile strength of at least 400 kgf/mm.sup.2 and a reduction of area of at least 40% and which are suitable for use as tire cords in automobile tires can be obtained by wire drawing of the steel wire.

    摘要翻译: PCT No.PCT / JP91 / 00188 Sec。 371日期1991年10月9日 102(e)1991年10月9日PCT 1991年2月15日PCT PCT。 WO91 / 12346 PCT公开号 日期:1991年8月22日。碳含量为0.7%-0.9重量%的高碳钢的线材进行热处理,以形成过冷奥氏体相,然后以降低的速率进行塑性变形 在低于Ae1点和500℃以上的温度范围内至少20%,并在不加热至奥氏体范围的情况下转变成珠光体。 所得珠光体的珠光体块大小不大于5.0μm。 具有拉伸强度为至少400kgf / mm 2,面积减小至少40%并适合用作汽车轮胎中的轮胎帘线的钢丝可以通过钢丝拉丝获得。

    TERMINAL FITTING
    20.
    发明申请
    TERMINAL FITTING 审中-公开
    端子接头

    公开(公告)号:US20140038473A1

    公开(公告)日:2014-02-06

    申请号:US14112756

    申请日:2012-04-17

    IPC分类号: H01R13/18

    摘要: The present invention provides a terminal fitting that ensures constant contact load of an inserter that is inserted into an electrical contact by making uniform the amounts of displacement among a plurality of resilient pieces constituting the electrical contact. A terminal fitting includes a cylindrical electrical contact portion obtained by making the both ends of the conductive metal plate close to each other and joined to each other. The electrical contact portion includes a plurality of slits extending in a cylinder-length direction N and provided at intervals in the circumferential direction of the electrical contact portion. The slits provided farthest away from the joining portion at the both ends of the metal plate have a size in the cylinder-length direction N larger than those of the other slits.

    摘要翻译: 本发明提供了一种端子接头,其通过使构成电接触件的多个弹性件之间的位移量均匀地确保插入到电接触件中的恒定的接触负载。 端子接头包括通过使导电金属板的两端彼此靠近并且彼此接合而获得的圆柱形电接触部分。 电接触部分包括在气缸长度方向N上延伸并沿电接触部分的圆周方向间隔设置的多个狭缝。 在金属板的两端处距离接合部分最远的狭缝具有比其他狭缝更大的气缸长度方向N的尺寸。