摘要:
This invention relates to new compounds, pharmaceutical compositions and diagnostic kits comprising such compounds, and methods of using such compounds for inhibiting NAALADase enzyme activity, detecting diseases where NAALADase levels are altered, effecting neuronal activity, effecting TGF-β activity, inhibiting angiogenesis, and treating glutamate abnormalities, neuropathy, pain, compulsive disorders, prostate diseases, cancers and glaucoma.
摘要:
This invention relates to new compounds, pharmaceutical compositions and diagnostic kits comprising such compounds, and methods of using such compounds for inhibiting NAALADase enzyme activity, detecting diseases where NAALAdase levels are altered, effecting neuronal activity, effecting TGF-β activity, inhibiting angiogenesis, and treating glutamate abnormalities, neuropathy, pain, compulsive disorders, prostate diseases, cancers and glaucoma.
摘要:
This invention relates to new compounds, pharmaceutical compositions and diagnostic kits comprising such compounds, and methods of using such compounds for inhibiting NAALADase enzyme activity, detecting diseases where NAALADase levels are altered, effecting neuronal activity, effecting TGF-&bgr; activity, inhibiting angiogenesis, and treating glutamate abnormalities, diabetic neuropathy, pain, compulsive disorders, prostate diseases, cancers and glaucoma.
摘要:
A liquid fuel for combustion appliances, in which a combustion wick for sucking up the fuel by the utilization of capillarity is used, contains an alcohol as a principal constituent and contains a hydrocarbon compound, which has approximately the same boiling point as that of the principal constituent, as a flame reaction agent. By the addition of the flame reaction agent, which is not accompanied by the occurrence of clogging of the combustion wick, the combustion flame of an alcohol, which otherwise produces a colorless flame, is colored and its visual perceptibility is thereby enhanced, such that the structure of the combustion appliance may be kept simple and the flame stability may be obtained reliably.
摘要:
The present invention relate to phosphinic alkanoic acid derivatives that inhibit N-Acetylated .alpha.-Linked Acidic Dipeptidase (NAALADase) enzyme activity, pharmaceutical compositions comprising the same, and methods of using the same to inhibit NAALADase activity and to treat glutamate abnormalities and prostate diseases.
摘要:
A low pressure CVD system comprising an inner tube having an upper end and a lower end opened, and made of a silicon carbide material, an outer tube including a circumferential wall surrounding an outer periphery of the inner tube with a predetermined spacing, an upper wall closing an upper end of the circumferential wall and a flange provided at a lower portion thereof, the outer tube having a lower end opened, a base portion for supporting the inner tube and the outer tube at the lower ends thereof, and for providing hermetic sealing between the lower end of the outer tube and the base portion, the base portion having a central portion formed with an opening, a lid provided for opening and shutting the opening in the base portion, and a furnace wall surrounding the circumferential wall and the upper wall of the outer tube, the furnace wall having a heater arranged on an inner side thereof wherein the outer tube is made of a silicon carbide material, and padding of a silicon carbide material is formed at a corner of a joined portion between the circumferential wall and the flange of the outer tube.
摘要:
Herein disclosed is a microcomputer MCU adopting the general purpose register method. The microcomputer is enabled to have a small program capacity or a high program memory using efficiency and a low system cost, while enjoying the advantage of simplification of the instruction decoding as in the RISC machine having a fixed length instruction format of the prior art, by adopting a fixed length instruction format having a power of 2 but a smaller bit number than that of the maximum data word length fed to instruction execution means. And, the control of the coded division is executed by noting the code bits.
摘要:
A steel wire for making a high strength steel wire product which contains 0.6-1.1% C, 0.2-0.6% Si, 0.3-0.8% Mn, and impurities of max 0.010% P, max 0.010% S, max 0.003% O(oxygen), and max 0.002% N, and has a structure in which the maximum pearlite block size is 4.0 .mu.m, the maximum separation distance in pearlite lamellars is 0.1 .mu.m, and the maximum content of free ferrite is 1% by volume.The steel wire can be manufactured in the process as follows;1 heating a steel wire rod having above-mentioned chemical composition to the austenite range above Ac.sub.3 point or A.sub.cm point,2 initiating plastic deformation to not less than 20% total reduction in cross-sectional area in the temperature range 850.degree. C. -750.degree. C.,3 finishing plastic deformation in the range below Ae.sub.1 point and above 650.degree. C., and4 continuously cooling to a range lower than 650.degree. C. and higher than 550.degree. C., and thus transforming into pearlite phase.
摘要:
A wire of a high-carbon steel having a carbon content of 0.7%-0.9% by weight is heat-treated so as to form supercooled austenitic phases, then subjected to plastic deformation with a reduction rate of at least 20% in the temperature range of below the Ae.sub.1 point and above 500.degree. C., and transformed into pearlite without heating to the austenitic range.The resulting pearlite has a pearlite block size of not greater than 5.0 .mu.m. Steel filaments which have a tensile strength of at least 400 kgf/mm.sup.2 and a reduction of area of at least 40% and which are suitable for use as tire cords in automobile tires can be obtained by wire drawing of the steel wire.
摘要:
The present invention provides a terminal fitting that ensures constant contact load of an inserter that is inserted into an electrical contact by making uniform the amounts of displacement among a plurality of resilient pieces constituting the electrical contact. A terminal fitting includes a cylindrical electrical contact portion obtained by making the both ends of the conductive metal plate close to each other and joined to each other. The electrical contact portion includes a plurality of slits extending in a cylinder-length direction N and provided at intervals in the circumferential direction of the electrical contact portion. The slits provided farthest away from the joining portion at the both ends of the metal plate have a size in the cylinder-length direction N larger than those of the other slits.