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    Method and device for monitoring the access to the cardiovascular system of a patient
    11.
    发明申请
    Method and device for monitoring the access to the cardiovascular system of a patient 有权
    用于监测患者心血管系统通路的方法和装置

    公开(公告)号：US20030036719A1

    公开(公告)日：2003-02-20

    申请号：US09914348

    申请日：2001-12-21

    Inventor： Sara Giacomelli ,  Ivan Rossi ,  Enrico Canini

    IPC: A61M037/00 ,  C02F001/44 ,  B01D061/00

    CPC classification number: A61M1/3669 ,  A61M1/16 ,  A61M1/3656 ,  A61M1/367 ,  A61M2205/13 ,  A61M2205/50

    Abstract: A device for monitoring the access to the cardiovascular system of a patient undergoing an extracorporeal treatment of blood in a machine (1) comprising a treatment device (4) and an extracorporeal circuit (2), comprises: a voltage generator (16) for generating a potential difference between a part of the machine (1) and a first point (B) of a venous branch (8) of the extracorporeal circuit (2), connecting the patient to the treatment device (4); a detector (17) for detecting the value (dV) of a quantity that correlates with the electric current along at least one section (10a; 10b; 10c) of the venous branch (10) between the first point (B) and a venous needle (13) fitted at the end of the venous branch (8) and inserted in the vascular system of the patient (P); calculating means (15) for comparing the detected value (dV) with a reference range (T).

    Abstract translation: 一种用于监测在包括治疗装置（4）和体外电路（2）的机器（1）中进行血液体外处理的患者的心血管系统的通路的装置，包括：电压发生器（16），用于产生 所述机器（1）的一部分与所述体外回路（2）的静脉分支（8）的第一点（B）之间的电位差，将所述患者连接到所述治疗装置（4）; 检测器（17），用于检测与第一点（B）和静脉（B）之间的静脉分支（10）的至少一个部分（10a; 10b; 10c）的电流相关的量的值（dV） 针头（13）安装在静脉分支（8）的端部并插入患者（P）的血管系统中; 用于将检测值（dV）与参考范围（T）进行比较的计算装置（15）。

    Method to measure blood flow and recirculation in hemodialysis shunts
    12.
    发明授权
    Method to measure blood flow and recirculation in hemodialysis shunts 失效
    测量血液透析分流术中血流和再循环的方法

    公开(公告)号：US06514419B2

    公开(公告)日：2003-02-04

    申请号：US09734352

    申请日：2000-12-11

    Applicant: Nikolai M. Krivitski

    Inventor： Nikolai M. Krivitski

    IPC: A61B5026

    CPC classification number: A61M1/3653 ,  A61B5/0275 ,  A61M1/16 ,  A61M1/3655 ,  A61M1/3658 ,  A61M1/3663 ,  A61M1/3669 ,  A61M1/367

    Abstract: The measurement of blood flow in a dialysis shunt is obtained by injection of an indicator material into a venous line leading from dialysis equipment to the shunt. The blood flow in an arterial line leading from the shunt at a location downstream of the venous line to the dialysis equipment is monitored by an arterial line sensor for the presence of the indicator material. A detector connected to the sensor provides a dilution curve in response to the presence of the indicator material and the blood flow in the shunt is calculated from the area under the dilution curve. The locations of the arterial and venous lines in the shunt can be reversed to obtain a measurement of blood recirculation from the venous line into the arterial line.

    Abstract translation: 通过将指示剂材料注射到从透析设备引导到分流器的静脉管线中，可以测量透析分流器中的血流量。 通过动脉线传感器监测从静脉线下游位置到分离设备的分流处的动脉线中的血液流动，以指示物质的存在。 连接到传感器的检测器响应于指示剂材料的存在而提供稀释曲线，并且根据稀释曲线下的面积计算分流器中的血流量。 分流器中的动脉和静脉线的位置可以反转，以获得从静脉线进入动脉线的血液再循环的测量。

    Intraoperative blood salvaging system and method
    14.
    发明授权
    Intraoperative blood salvaging system and method 失效
    术中血液回收系统及方法

    公开(公告)号：US5876611A

    公开(公告)日：1999-03-02

    申请号：US876557

    申请日：1997-06-16

    Applicant: U. Ramakrishna Shettigar

    Inventor： U. Ramakrishna Shettigar

    IPC: A61M1/34 ,  A61M1/36 ,  B01D61/14 ,  B01D61/16 ,  B01D61/22 ,  B01D61/00 ,  A61M1/00 ,  B01D61/18

    CPC classification number: B01D61/147 ,  A61M1/3621 ,  A61M1/3692 ,  B01D61/16 ,  B01D61/22 ,  A61M1/34 ,  A61M1/3643 ,  A61M1/3669 ,  A61M2205/7554

    Abstract: An apparatus is disclosed for salvaging a patient's own blood during intraoperative surgical procedures and reinfusing the blood, washed and filtered, to the patient substantially continuously, on-line and in real-time. The apparatus comprises suction means, admixing means for admixing aspirated blood with a washing fluid, filtering means for filtering the admixture through an emboli filter, monitoring means for measuring the amount of cellular component volume in the aspirated, filtered blood, filtration means for removing excess fluid and impurities from the blood, and reinfusion means for introducing the washed and filtered blood to the patient free of emboli. The apparatus is structured to introduce washing fluid to the aspirated blood in proportion to the measured hematocrit level of the blood that is aspirated. Methods are disclosed for priming of the system, cleaning and flushing the apparatus of blood clots and debris by means of reverse filtration and filtration of blood for reinfusion. Methods for automated control of the blood salvaging system and operation are also disclosed.

    Abstract translation: 公开了一种用于在术中外科手术过程中抢救患者自己的血液并将血液进行洗涤和过滤的装置，基本上连续地，在线和实时地回送给患者。 该装置包括抽吸装置，用于将抽吸的血液与洗涤液混合的混合装置，用于通过栓塞过滤器过滤混合物的过滤装置，用于测量吸入的，过滤的血液中的细胞组分体积的量的监测装置，用于除去过量的过滤装置 来自血液的流体和杂质，以及用于将经洗涤和过滤的血液引入到没有栓塞的患者的再灌注装置。 该装置的结构是将洗涤液与被抽吸的血液测量的血细胞比容水平成比例地将吸入的血液引入吸入的血液。 公开了用于引发系统的方法，通过反向过滤和用于再灌注的血液的过滤来清洗和冲洗血块和碎片的装置。 还公开了用于自动控制血液回收系统和操作的方法。

    Hematocrit measuring instrument
    15.
    发明授权
    Hematocrit measuring instrument 失效
    血细胞比容测量仪

    公开(公告)号：US4484135A

    公开(公告)日：1984-11-20

    申请号：US406878

    申请日：1982-08-10

    Applicant: Toshikazu Ishihara ,  Hazime Inagaki

    Inventor： Toshikazu Ishihara ,  Hazime Inagaki

    IPC: A61B5/145 ,  A61B5/1473 ,  A61B5/1495 ,  A61M1/36 ,  G01N27/06 ,  G01N33/48 ,  G01N33/487 ,  G01N33/49

    CPC classification number: G01N33/49 ,  A61M1/3609 ,  A61M1/3669

    Abstract: A hematocrit measuring instrument of the type which determines hematocrit of blood from the electrical resistivity of the blood is provided with a blood resistivity measurement device, an ultrafilter for filtering a part of the plasma from the blood, a filtrate resistivity measurement device for measuring the resistivity of the filtrate from the ultrafilter and an arithmetic circuit for calculating the hematocrit of the blood from the resistivities of the blood and the filtrate. The hematocrit measuring instrument is connected into a circulatory path for the blood outside of the patient's body and continuously measures the hematocrit of the blood from the resistivity of the blood and the resistivity of the filtrate from the ultrafilter.

    Abstract translation: 从血液电阻率测定血液血细胞比容的血细胞比容测定仪具有血液电阻测定装置，过滤血液中的一部分血浆的超滤器，测定电阻率的滤液电阻率测定装置 的滤液和用于从血液和滤液的电阻率计算血液的血细胞比容的算术电路。 血细胞比容测量仪器连接到患者身体外的血液的循环路径，并连续测量血液的血细胞比容从血液的电阻率和滤液的电阻率。

    Disposable, pre-calibrated, pre-validated sensors for use in bio-processing applications
    20.
    发明授权
    Disposable, pre-calibrated, pre-validated sensors for use in bio-processing applications 有权
    一次性，预校准，预先验证的传感器，用于生物处理应用

    公开(公告)号：US07857506B2

    公开(公告)日：2010-12-28

    申请号：US11294296

    申请日：2005-12-05

    Applicant: Karl G. Schick ,  David Uhen

    Inventor： Karl G. Schick ,  David Uhen

    IPC: G01N27/00 ,  G01N33/48

    CPC classification number: G01N27/10 ,  A61M1/3621 ,  A61M1/3669 ,  A61M2205/6018

    Abstract: Disposable, pre-sterilized, and pre-calibrated, pre-validated conductivity sensors are provided. These sensors are designed to store sensor-specific information, such as calibration and production information, in a non-volatile memory chip on the sensor. The sensors are calibrated using 0.100 molar potassium chloride (KCl) solutions at 25 degrees Celsius. These sensors may be utilize with in-line systems, closed fluid circuits, bioprocessing systems, or systems which require an aseptic environment while avoiding or reducing cleaning procedures and quality assurance variances.

    Abstract translation: 提供一次性，预消毒和预校准的预验证的电导率传感器。 这些传感器设计用于将传感器特定信息（如校准和生产信息）存储在传感器上的非易失性存储器芯片中。 传感器在25摄氏度下使用0.100摩尔氯化钾（KCl）溶液进行校准。 这些传感器可以利用在线系统，封闭流体回路，生物处理系统或需要无菌环境同时避免或减少清洁程序和质量保证差异的系统。

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