公开(公告)号：US5683384A

公开(公告)日：1997-11-04

申请号：US515379

申请日：1995-08-15

Applicant: Edward J. Gough ,  Alan A. Stein ,  Stuart D. Edwards

Inventor： Edward J. Gough ,  Alan A. Stein ,  Stuart D. Edwards

IPC: A61B17/22 ,  A61B17/00 ,  A61B17/34 ,  A61B18/00 ,  A61B18/04 ,  A61B18/12 ,  A61B18/14 ,  A61B18/16 ,  A61B18/18 ,  A61M3/02 ,  A61M25/00 ,  A61N1/06 ,  A61N1/40 ,  A61N5/04 ,  A61B17/39

CPC classification number: A61N1/403 ,  A61B18/1477 ,  A61B18/1482 ,  A61B18/18 ,  A61B18/1815 ,  A61N1/06 ,  A61B18/1206 ,  A61B18/14 ,  A61B18/1402 ,  A61B18/1485 ,  A61B18/1492 ,  A61B2017/00022 ,  A61B2017/00101 ,  A61B2018/00011 ,  A61B2018/00023 ,  A61B2018/00196 ,  A61B2018/00273 ,  A61B2018/00452 ,  A61B2018/00476 ,  A61B2018/00577 ,  A61B2018/00666 ,  A61B2018/00678 ,  A61B2018/00702 ,  A61B2018/00708 ,  A61B2018/00726 ,  A61B2018/00744 ,  A61B2018/00761 ,  A61B2018/00779 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/00827 ,  A61B2018/00875 ,  A61B2018/00892 ,  A61B2018/124 ,  A61B2018/1253 ,  A61B2018/126 ,  A61B2018/1425 ,  A61B2018/143 ,  A61B2018/1432 ,  A61B2018/1435 ,  A61B2018/1472 ,  A61B2018/162 ,  A61B2218/002 ,  A61M25/007 ,  A61M3/0279 ,  A61N5/04

Abstract: An ablation apparatus has a multiple antenna device of adjustable length including an adjustable length primary antenna and an adjustable length secondary antenna. The primary antenna has a longitudinal axis, and the secondary antenna is deployed in a direction lateral to the longitudinal axis. The secondary antenna is constructed to be structurally less rigid than the primary antenna. The adjustable lengths of the primary and secondary antennas permits a desired geometric ablation of a selected tissue mass. An adjustable insulation sleeve is positioned on an exterior of one of the primary or secondary antennas. An energy source is connected to the multiple antenna device. A variety of energy sources can be used including RF, microwave and laser.

Abstract translation: 消融装置具有可调长度的多天线装置，包括可调长度的主天线和可调长度的辅助天线。 主天线具有纵向轴线，并且辅助天线在纵向轴线的横向方向上展开。 次级天线被构造成在结构上比主天线刚性更低。 初级和次级天线的可调节长度允许所选择的组织块的期望的几何消融。 一个可调整的绝缘套管位于主天线或辅助天线之一的外部。 能量源连接到多天线装置。 可以使用各种能源，包括射频，微波和激光。

公开(公告)号：US5599295A

公开(公告)日：1997-02-04

申请号：US555519

申请日：1995-11-08

Applicant: Arye Rosen ,  Stuart D. Edwards ,  Ronald G. Lax ,  Hugh R. Sharkey ,  Ingemar H. Lundquist ,  Paul Walinsky

Inventor： Arye Rosen ,  Stuart D. Edwards ,  Ronald G. Lax ,  Hugh R. Sharkey ,  Ingemar H. Lundquist ,  Paul Walinsky

IPC: A61B10/00 ,  A61B10/02 ,  A61B10/06 ,  A61B17/00 ,  A61B17/22 ,  A61B17/24 ,  A61B17/28 ,  A61B17/34 ,  A61B18/00 ,  A61B18/08 ,  A61B18/14 ,  A61B18/18 ,  A61B18/22 ,  A61B18/24 ,  A61B19/00 ,  A61F7/00 ,  A61M1/00 ,  A61M3/02 ,  A61M25/00 ,  A61N1/06 ,  A61N1/40 ,  A61N5/02 ,  A61N5/04 ,  A61B17/39

CPC classification number: A61B18/00 ,  A61B10/0233 ,  A61B10/0275 ,  A61B10/06 ,  A61B18/1477 ,  A61B18/1485 ,  A61B18/18 ,  A61B18/1815 ,  A61B18/24 ,  A61N1/06 ,  A61N1/40 ,  A61N1/403 ,  A61N5/02 ,  A61N5/045 ,  A61B10/02 ,  A61B10/0241 ,  A61B18/082 ,  A61B18/1206 ,  A61B18/14 ,  A61B18/1402 ,  A61B18/1442 ,  A61B18/148 ,  A61B18/1482 ,  A61B2017/00084 ,  A61B2017/00092 ,  A61B2017/00101 ,  A61B2017/00106 ,  A61B2017/00123 ,  A61B2017/00181 ,  A61B2017/00194 ,  A61B2017/00274 ,  A61B2017/00292 ,  A61B2017/003 ,  A61B2017/00867 ,  A61B2017/22038 ,  A61B2017/22072 ,  A61B2017/22077 ,  A61B2017/22082 ,  A61B2017/248 ,  A61B2017/2939 ,  A61B2017/3488 ,  A61B2018/00005 ,  A61B2018/00011 ,  A61B2018/00041 ,  A61B2018/00083 ,  A61B2018/00095 ,  A61B2018/00101 ,  A61B2018/00196 ,  A61B2018/0022 ,  A61B2018/00547 ,  A61B2018/00577 ,  A61B2018/00678 ,  A61B2018/00702 ,  A61B2018/00726 ,  A61B2018/00744 ,  A61B2018/00761 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/00821 ,  A61B2018/00886 ,  A61B2018/0091 ,  A61B2018/00916 ,  A61B2018/00946 ,  A61B2018/0097 ,  A61B2018/00982 ,  A61B2018/1253 ,  A61B2018/126 ,  A61B2018/1273 ,  A61B2018/128 ,  A61B2018/1412 ,  A61B2018/1425 ,  A61B2018/2238 ,  A61B2090/0814 ,  A61B2090/3614 ,  A61B2090/378 ,  A61B2090/3782 ,  A61B2090/3786 ,  A61B2090/3925 ,  A61B2217/005 ,  A61B2217/007 ,  A61F2007/0054 ,  A61M2025/0086 ,  A61M2025/0087 ,  A61M2025/0089 ,  A61M2025/009 ,  A61M2025/0096 ,  A61M2025/018 ,  A61M25/0068 ,  A61M3/0279 ,  A61N5/04

Abstract: A medical probe device comprising a catheter having a stylet guide housing with at least one stylet port in a side thereof and stylet guide means for directing a flexible stylet outward through at least one stylet port and through intervening tissue to targeted tissue. The stylet comprises an electrical central conductor which is enclosed within an insulating or dielectric sleeve surrounded by a conductive layer terminated by an antenna to selectively deliver microwave or radio frequency energy to target tissue. One embodiment includes the electrical conductor being enclosed within a non-conductive sleeve which itself is enclosed within a conductive sleeve in a coaxial cable arrangement to form a microwave transmission line terminated by an antenna. Another embodiment includes a resistive element near the distal end of the stylet which couples the center electrode to an outer conductor to generate joulian heat as electromagnetic energy is applied, such as an RF signal.

Abstract translation: 一种医疗探针装置，其包括导管，其具有在其一侧具有至少一个管心针端口的探针引导壳体和用于通过至少一个通管孔向外引导柔性探针管的探针引导装置，并通过介入组织到目标组织。 探针包括电中心导体，该中心导体封闭在由天线端接的导电层围绕的绝缘或介电套筒内，以选择性地将微波或射频能量传送到目标组织。 一个实施例包括电导体被封装在非导电套筒内，其本身以同轴电缆布置封装在导电套筒内，以形成由天线端接的微波传输线。 另一个实施例包括在探针的远端附近的电阻元件，其将中心电极耦合到外部导体，以在施加电磁能时（例如RF信号）产生joulian热。

公开(公告)号：US5569242A

公开(公告)日：1996-10-29

申请号：US389924

申请日：1995-02-16

Applicant: Ronald G. Lax ,  Gary S. Fanton ,  Stuart D. Edwards

Inventor： Ronald G. Lax ,  Gary S. Fanton ,  Stuart D. Edwards

IPC: A61B17/56 ,  A61B18/00 ,  A61B18/12 ,  A61B18/14 ,  A61N1/06 ,  A61N1/40 ,  A61B17/36

CPC classification number: A61B18/148 ,  A61N1/40 ,  A61B2018/00023 ,  A61B2018/00083 ,  A61B2018/00452 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2018/143 ,  A61B2018/1472 ,  A61B2018/1497 ,  A61B2018/1861

Abstract: An apparatus and method are provided for control contraction of tissue that includes collagen fibers. The apparatus includes a handpiece, and an electrode with an electrode proximal end associated with the handpiece. A distal end of the electrode has a geometry that delivers a controlled amount of energy to the tissue for a desired contraction of the collagen fibers. This is achieved while dissociation and breakdown of the collagen fibers is minimized. The handpiece, with electrode, is adapted to be introduced through an operating cannula in percutaneous applications. Additionally, an operating cannula may be included in the apparatus and be attached to the handpiece. The apparatus and method provides for a desired level of contraction of collagen soft tissue without dissociation or breakdown of collagen fibers.

公开(公告)号：US5558672A

公开(公告)日：1996-09-24

申请号：US286862

申请日：1994-08-04

Applicant: Stuart D. Edwards ,  Kee S. Lee ,  James Baker ,  Bruno Strul

Inventor： Stuart D. Edwards ,  Kee S. Lee ,  James Baker ,  Bruno Strul

IPC: A61B17/00 ,  A61B17/42 ,  A61B18/00 ,  A61B18/14 ,  A61B18/18 ,  A61F2/958 ,  A61M3/02 ,  A61M16/04 ,  A61N1/06 ,  A61N1/08 ,  A61B17/39

CPC classification number: A61B18/148 ,  A61B18/1485 ,  A61B18/1492 ,  A61M16/0481 ,  A61N1/06 ,  A61N1/08 ,  A61B18/18 ,  A61B2017/00084 ,  A61B2017/00106 ,  A61B2017/4216 ,  A61B2018/00065 ,  A61B2018/00083 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00559 ,  A61B2018/00577 ,  A61B2018/00654 ,  A61B2018/00666 ,  A61B2018/00678 ,  A61B2018/00702 ,  A61B2018/00708 ,  A61B2018/00761 ,  A61B2018/00791 ,  A61B2018/00827 ,  A61B2018/00869 ,  A61B2018/00875 ,  A61B2018/00886 ,  A61B2018/00892 ,  A61B2018/00898 ,  A61B2018/0091 ,  A61B2018/00916 ,  A61B2018/00982 ,  A61B2018/124 ,  A61B2018/1472 ,  A61B2218/002 ,  A61M2025/1052 ,  A61M2025/1086 ,  A61M25/1002 ,  A61M3/0279

Abstract: An ablation apparatus has an expandable member that is inserted into an organ of a body and ablates all or a selected portion of the inner layer of the organ. Electrolytic solution fills the expandable member, and the expandable member includes a plurality of apertures from which electrolytic solution flows from the expandable member. First and second fluid conduits, which can be first and second conforming members, are in a surrounding relationship to the expandable member. The second conforming member, including a conductive surface, is made of a material that provides substantial conformity between the conductive surface and a shape of the inner layer of the organ. A plurality of electrodes is positioned between the two conforming members. The expandable member serves as an insulator to RF energy. Each electrode includes an insulator formed on a surface of the electrode positioned adjacent to the second conforming member. The combination of sandwiching the electrodes between the two conforming members, and the use of two insulators, one on the electrode and the other on the expandable member, provides selectable ablation of the inner layer of the organ. A feedback device is included and is responsive to a detected characteristic of the inner layer. The feedback device provides a controlled delivery of RF energy to the electrodes.

公开(公告)号：US5556377A

公开(公告)日：1996-09-17

申请号：US172448

申请日：1993-12-22

Applicant: Arye Rosen ,  Stuart D. Edwards ,  Ronald G. Lax ,  Hugh R. Sharkey ,  Ingemar H. Lundquist

Inventor： Arye Rosen ,  Stuart D. Edwards ,  Ronald G. Lax ,  Hugh R. Sharkey ,  Ingemar H. Lundquist

IPC: A61B10/00 ,  A61B10/02 ,  A61B10/06 ,  A61B17/00 ,  A61B17/22 ,  A61B17/24 ,  A61B17/28 ,  A61B17/34 ,  A61B18/00 ,  A61B18/08 ,  A61B18/14 ,  A61B18/18 ,  A61B18/22 ,  A61B18/24 ,  A61B19/00 ,  A61F7/00 ,  A61M1/00 ,  A61M3/02 ,  A61M25/00 ,  A61N1/06 ,  A61N1/40 ,  A61N5/02 ,  A61N5/04 ,  A61B17/39

CPC classification number: A61B10/0233 ,  A61B10/0275 ,  A61B10/06 ,  A61B18/00 ,  A61B18/1477 ,  A61B18/1485 ,  A61B18/18 ,  A61B18/1815 ,  A61B18/24 ,  A61N1/06 ,  A61N1/40 ,  A61N1/403 ,  A61N5/02 ,  A61N5/045 ,  A61B10/0241 ,  A61B18/082 ,  A61B18/1206 ,  A61B18/14 ,  A61B18/1402 ,  A61B18/1442 ,  A61B18/148 ,  A61B18/1482 ,  A61B2017/00084 ,  A61B2017/00092 ,  A61B2017/00101 ,  A61B2017/00106 ,  A61B2017/00123 ,  A61B2017/00181 ,  A61B2017/00194 ,  A61B2017/00274 ,  A61B2017/00292 ,  A61B2017/003 ,  A61B2017/00867 ,  A61B2017/22038 ,  A61B2017/22072 ,  A61B2017/22077 ,  A61B2017/22082 ,  A61B2017/248 ,  A61B2017/2939 ,  A61B2017/3488 ,  A61B2018/00005 ,  A61B2018/00011 ,  A61B2018/00041 ,  A61B2018/00083 ,  A61B2018/00095 ,  A61B2018/00101 ,  A61B2018/00196 ,  A61B2018/0022 ,  A61B2018/00547 ,  A61B2018/00577 ,  A61B2018/00678 ,  A61B2018/00702 ,  A61B2018/00726 ,  A61B2018/00744 ,  A61B2018/00761 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/00821 ,  A61B2018/00886 ,  A61B2018/0091 ,  A61B2018/00916 ,  A61B2018/00946 ,  A61B2018/0097 ,  A61B2018/00982 ,  A61B2018/1253 ,  A61B2018/126 ,  A61B2018/1273 ,  A61B2018/128 ,  A61B2018/1425 ,  A61B2018/2238 ,  A61B2090/0814 ,  A61B2090/3614 ,  A61B2090/378 ,  A61B2090/3782 ,  A61B2090/3786 ,  A61B2090/3925 ,  A61B2217/005 ,  A61B2217/007 ,  A61F2007/0054 ,  A61M2025/0086 ,  A61M2025/0087 ,  A61M2025/0089 ,  A61M2025/0096 ,  A61M2025/018 ,  A61M25/0068 ,  A61M25/0082 ,  A61M3/0279 ,  A61N5/04

Abstract: A medical probe apparatus comprising a catheter having a stylet guide housing with at least one stylet port in a side thereof and stylet guide means for directing a flexible stylet outward through at least one stylet port and through intervening tissue to targeted tissues. The stylet guide has an integrated circuit or semiconductor apparatus at the distal end thereof to generate electromagnetic radiation directly at the point of the desired target tissue. The stylet includes at least one semiconductor or integrated circuit radiation emitter adapted for electromagnetic radiation when electrically energized. An elongated electrical insulator includes proximal and distal ends adapted to be introduced into a body opening, such as the urethra. First and second elongated electrical conductors are electrically isolated by the insulator. The distal ends of the electrical conductors are connected to the semiconductor, so that electrical energy coupled to the proximal ends of the conductors energizes the semiconductor to cause radiation. In a particular embodiment of the invention, the semiconductor radiation emitter(s) is (are) a laser(s). In another embodiment, it is a microwave oscillator or integrated circuit. In yet another embodiment, two types of semiconductor radiator emitters are located distally on the catheter, and each type is connected to one of the electrical conductors. According to one aspect of the invention, a third conductor may be connected in common to both types of semiconductor radiation emitters. The stylet may include an antenna to aid in coupling radiation from a semiconductor radiation emitter to the surrounding tissue. The stylet may also include an axial aperture adapted for use with a guide filament.

Abstract translation: 一种医疗探针装置，包括具有探针引导壳体的导管，所述探针引导壳体的侧面具有至少一个管心针口，以及探针引导装置，用于通过至少一个管心针向外引导柔性探针，并通过介入组织引导到靶组织。 探针引导件在其远端具有集成电路或半导体装置，以在期望的目标组织的点处直接产生电磁辐射。 探针包括至少一个半导体或集成电路辐射发射器，当电通电时适用于电磁辐射。 细长的电绝缘体包括适于引入诸如尿道的体开口中的近端和远端。 第一和第二细长电导体被绝缘体电隔离。 电导体的远端连接到半导体，使得耦合到导体的近端的电能激励半导体以引起辐射。 在本发明的一个特定实施例中，半导体辐射发射器是（或多个）激光器。 在另一个实施例中，它是微波振荡器或集成电路。 在另一个实施例中，两种类型的半导体辐射器发射器位于导管的远端，并且每种类型连接到电导体之一。 根据本发明的一个方面，第三导体可以共同连接到两种类型的半导体辐射发射器。 探针可以包括天线，以帮助将来自半导体辐射发射器的辐射耦合到周围的组织。 探针还可以包括适于与导丝一起使用的轴向孔。

公开(公告)号：US5536240A

公开(公告)日：1996-07-16

申请号：US313719

申请日：1994-09-27

Applicant: Stuart D. Edwards ,  Ronald G. Lax ,  Ingemar H. Lundquist ,  Hugh R. Sharkey

Inventor： Stuart D. Edwards ,  Ronald G. Lax ,  Ingemar H. Lundquist ,  Hugh R. Sharkey

IPC: A61B5/01 ,  A61B10/00 ,  A61B10/02 ,  A61B10/06 ,  A61B17/00 ,  A61B17/22 ,  A61B17/24 ,  A61B17/28 ,  A61B17/34 ,  A61B18/00 ,  A61B18/08 ,  A61B18/14 ,  A61B18/18 ,  A61B18/22 ,  A61B18/24 ,  A61B19/00 ,  A61F7/00 ,  A61M1/00 ,  A61M3/02 ,  A61M25/00 ,  A61M25/092 ,  A61M25/14 ,  A61N1/06 ,  A61N1/40 ,  A61N5/02 ,  A61N5/04 ,  A61N5/06 ,  A61B17/39

CPC classification number: A61N5/02 ,  A61B18/00 ,  A61B18/1477 ,  A61B18/1485 ,  A61B18/18 ,  A61B18/1815 ,  A61N1/06 ,  A61N1/40 ,  A61N1/403 ,  A61N5/045 ,  A61B10/02 ,  A61B10/0241 ,  A61B18/082 ,  A61B18/1206 ,  A61B18/14 ,  A61B18/1442 ,  A61B18/148 ,  A61B18/24 ,  A61B2017/00084 ,  A61B2017/00092 ,  A61B2017/00106 ,  A61B2017/00274 ,  A61B2017/00292 ,  A61B2017/003 ,  A61B2017/00867 ,  A61B2017/22072 ,  A61B2017/22077 ,  A61B2017/22082 ,  A61B2017/248 ,  A61B2017/2939 ,  A61B2017/3488 ,  A61B2018/00005 ,  A61B2018/00011 ,  A61B2018/00083 ,  A61B2018/00095 ,  A61B2018/00196 ,  A61B2018/0022 ,  A61B2018/00547 ,  A61B2018/00577 ,  A61B2018/00678 ,  A61B2018/00702 ,  A61B2018/00726 ,  A61B2018/00744 ,  A61B2018/0075 ,  A61B2018/00761 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/00821 ,  A61B2018/00869 ,  A61B2018/00886 ,  A61B2018/0091 ,  A61B2018/00916 ,  A61B2018/00946 ,  A61B2018/00982 ,  A61B2018/1253 ,  A61B2018/126 ,  A61B2018/1273 ,  A61B2018/128 ,  A61B2018/1412 ,  A61B2018/1425 ,  A61B2018/1861 ,  A61B2018/2238 ,  A61B2090/0814 ,  A61B2090/3614 ,  A61B2090/3782 ,  A61B2090/3925 ,  A61F2007/0054 ,  A61M2025/0086 ,  A61M2025/0087 ,  A61M2025/0089 ,  A61M2025/009 ,  A61M2025/0096 ,  A61M2025/018 ,  A61M25/0068 ,  A61M25/0069 ,  A61M25/008 ,  A61M25/0082 ,  A61M3/0279 ,  A61N5/04

Abstract: A method for the treatment of benign prostatic hypertrophy in the prostate of the human male having a bladder with a base and a penis with a urethra therein formed by a urethral wall extending into the base of the bladder along a longitudinal axis with the prostate having tissue surrounding the urethral near the base of the bladder comprising selecting a target volume of the tissue of the prostate beyond the urethral wall, introducing radio frequency energy through the urethral wall into the target volume of the tissue of the prostate to cause ablation of tissue in the target volume of the tissue in the prostate and protecting the urethral wall from ablation by the radio frequency energy supplied to the target volume of tissue in the prostate.

Abstract translation: 一种用于治疗人类前列腺的良性前列腺肥大的方法，所述前列腺具有膀胱与基部和阴茎，其中尿道由尿道壁形成，所述尿道壁沿着纵向轴线延伸到膀胱的基部，前列腺具有组织 围绕膀胱基部附近的尿道，包括选择前列腺组织的目标体积超过尿道壁，将射频能量通过尿道壁引入前列腺组织的目标体积，以引起组织中的消融 前列腺组织的目标体积，并通过提供给前列腺组织的靶体积的射频能量来保护尿道壁免于消融。

公开(公告)号：US5509419A

公开(公告)日：1996-04-23

申请号：US168476

申请日：1993-12-16

Applicant: Stuart D. Edwards ,  Thomas F. Kordis ,  David K. Swanson

Inventor： Stuart D. Edwards ,  Thomas F. Kordis ,  David K. Swanson

IPC: A61B5/042 ,  A61B18/14 ,  A61B18/18 ,  A61L29/08 ,  A61L29/14 ,  A61L31/10 ,  A61L31/14 ,  A61N1/05 ,  A61N5/02

CPC classification number: A61B5/6856 ,  A61B5/0422 ,  A61B5/6852 ,  A61B5/6853 ,  A61B5/6858 ,  A61B5/6859 ,  A61L29/085 ,  A61L29/145 ,  A61L31/10 ,  A61L31/145 ,  A61N1/056 ,  A61B18/14 ,  A61B18/18 ,  A61B2562/0209 ,  A61B2562/043 ,  Y10T29/49002 ,  Y10T29/49117

Abstract: An electrode assembly for use in interventricular cardiac mapping includes one or more elongated splines each of which carries a plurality of spaced apart electrodes thereon. The body of each spline is formed of a plurality of alternating electrically conductive layers and the electrically non-conductive layers. A separate electrically conductive pathway is provided to connect each of the electrodes to a different one of the conductive layers. Each of the layers is electrically connected to an electrical signal processing device so that signals provided by each of the electrodes can he processed.

Abstract translation: 用于室间心脏映射的电极组件包括一个或多个细长花键，每个细长花键在其上承载多个间隔开的电极。 每个花键的主体由多个交替导电层和非导电层形成。 提供单独的导电路径以将每个电极连接到不同的一个导电层。 每个层电连接到电信号处理装置，使得可以处理由每个电极提供的信号。

公开(公告)号：US5505730A

公开(公告)日：1996-04-09

申请号：US265459

申请日：1994-06-24

Applicant: Stuart D. Edwards

Inventor： Stuart D. Edwards

IPC: A61B17/00 ,  A61B17/42 ,  A61B18/00 ,  A61B18/14 ,  A61B18/18 ,  A61F2/958 ,  A61M3/02 ,  A61M16/04 ,  A61N1/06 ,  A61N1/08 ,  A61B17/36

CPC classification number: A61B18/148 ,  A61B18/1485 ,  A61B18/1492 ,  A61M16/0481 ,  A61N1/06 ,  A61N1/08 ,  A61B18/18 ,  A61B2017/00084 ,  A61B2017/00106 ,  A61B2017/4216 ,  A61B2018/00065 ,  A61B2018/00083 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00559 ,  A61B2018/00577 ,  A61B2018/00654 ,  A61B2018/00666 ,  A61B2018/00678 ,  A61B2018/00702 ,  A61B2018/00708 ,  A61B2018/00761 ,  A61B2018/00791 ,  A61B2018/00827 ,  A61B2018/00869 ,  A61B2018/00875 ,  A61B2018/00886 ,  A61B2018/00892 ,  A61B2018/00898 ,  A61B2018/0091 ,  A61B2018/00916 ,  A61B2018/00982 ,  A61B2018/124 ,  A61B2018/1472 ,  A61B2218/002 ,  A61M2025/1052 ,  A61M2025/1086 ,  A61M25/1002 ,  A61M3/0279

Abstract: An ablation apparatus has a balloon that is inserted into an organ of a body and ablates all or a selected portion of the inner layer of the organ. Electrolytic solution fills the balloon, and the balloon includes a plurality of apertures from which electrolytic solution flows from the balloon. The flow rate of electrolytic solution is dependent on the pressure applied to the balloon by the electrolytic solution. A conforming member, with a conductive surface and a back side, is made of a material that substantially conforms to a shape of the inner layer of the organ and delivers the electrolytic solution and RF energy through the conductive surface to the inner layer. Advantageously, difficult to access areas are reached with the inclusion of the conforming member. Optionally positioned between the conforming member and the balloon is a porous membrane. A printed circuit is printed in or on the conforming member and delivers RF energy to selected sections of the inner layer. The printed circuit provides for the monitoring of impedance, temperature and circuit continuity. Additionally, the printed circuit can be multiplexed.

Abstract translation: 消融装置具有插入到身体器官中并消融器官内层的全部或选定部分的气囊。 电解液填充气囊，气球包括多个孔，电解溶液从气孔中流出。 电解液的流速取决于电解液对球囊施加的压力。 具有导电表面和背面的符合构件由基本上符合器官内层形状的材料制成，并将电解溶液和RF能量通过导电表面输送到内层。 有利地，通过包含符合标准的构件来达到难以进入的区域。 任选地位于适形构件和球囊之间的是多孔膜。 将印刷电路印刷在合格部件中或其上，并将RF能量传送到内层的选定部分。 印刷电路提供了对阻抗，温度和电路连续性的监控。 此外，可以复用印刷电路。

公开(公告)号：US5471982A

公开(公告)日：1995-12-05

申请号：US951728

申请日：1992-09-29

Applicant: Stuart D. Edwards ,  Jerome Jackson ,  Ingemar H. Lundquist ,  Thomas F. Kordis ,  Alan L. Kaganov

Inventor： Stuart D. Edwards ,  Jerome Jackson ,  Ingemar H. Lundquist ,  Thomas F. Kordis ,  Alan L. Kaganov

IPC: A61B5/042 ,  A61B18/14 ,  A61N1/06 ,  A61B5/0402

CPC classification number: A61B5/6856 ,  A61B18/1492 ,  A61B5/0422 ,  A61B5/6853 ,  A61B5/6858 ,  A61B5/6859 ,  A61N1/06 ,  A61B2017/22038 ,  A61B2018/00083 ,  A61B2018/00148 ,  A61B2018/0016 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00357 ,  A61B2018/00839 ,  A61B2018/1861 ,  A61B2562/0209 ,  A61B2562/043

Abstract: An improved probe for cardiac diagnosis and/or treatment includes a control handle and a catheter for insertion into the heart. The catheter has a distal end, a proximal end and at least one lumen connecting said distal and proximal ends. It also includes a flexible inner tube and an outer sheath enveloping said tube. At least one measuring electrode or ablation device is attached to the distal end of the tube. The outer sheath and the inner tube are rotatable relative to each other so that the electrode or device can be rotated within the heart without rotating the outer sheath. The sheath is also axially movable relative to the tube to selectively enclose or expose the electrode or device for use.

Abstract translation: 用于心脏诊断和/或治疗的改进探针包括控制手柄和用于插入心脏的导管。 导管具有远端，近端和连接所述远端和近端的至少一个腔。 它还包括柔性内管和包封所述管的外护套。 至少一个测量电极或消融装置附接到管的远端。 外鞘和内管可相对于彼此旋转，使得电极或装置可以在心脏内旋转而不旋转外护套。 鞘也可以相对于管轴向移动，以选择性地包围或暴露电极或装置以供使用。

公开(公告)号：US5458596A

公开(公告)日：1995-10-17

申请号：US238862

申请日：1994-05-06

Applicant: Ronald G. Lax ,  Gary S. Fanton ,  Stuart D. Edwards

Inventor： Ronald G. Lax ,  Gary S. Fanton ,  Stuart D. Edwards

IPC: A61B17/56 ,  A61B18/00 ,  A61B18/12 ,  A61B18/14 ,  A61N1/06 ,  A61N1/40

CPC classification number: A61B18/148 ,  A61N1/40 ,  A61B2018/00023 ,  A61B2018/00083 ,  A61B2018/00452 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2018/143 ,  A61B2018/1472 ,  A61B2018/1497 ,  A61B2018/1861

Abstract: An apparatus and method are provided for control contraction of tissue that includes collagen fibers. The apparatus includes a handpiece, and an electrode with an electrode proximal end associated with the handpiece. A distal end of the electrode has a geometry that delivers a controlled amount of energy to the tissue for a desired contraction of the collagen fibers. This is achieved while dissociation and breakdown of the collagen fibers is minimized. The handpiece, with electrode, is adapted to be introduced through an operating cannula in percutaneous applications. Additionally, an operating cannula may be included in the apparatus and be attached to the handpiece. The apparatus and method provides for a desired level of contraction of collagen soft tissue without dissociation or breakdown of collagen fibers.