公开(公告)号：US20170261491A1

公开(公告)日：2017-09-14

申请号：US15606954

申请日：2017-05-26

Applicant: DexCom, Inc.

Inventor： Naresh C. Bhavaraju ,  Arturo Garcia ,  Hari Hampapuram ,  Apurv Ullas Kamath ,  Aarthi Mahalingam ,  Dmytro Sokolovskyy ,  Stephen J. Vanslyke

IPC: G01N33/487 ,  G06F19/00 ,  G01M99/00

CPC classification number: G01N33/48792 ,  A61B5/14532 ,  A61B5/1495 ,  A61B5/7221 ,  A61B2560/0223 ,  A61B2560/0266 ,  A61B2560/0276 ,  A61B2560/028 ,  G01M99/008 ,  G01N33/49 ,  G01N33/66 ,  G06F19/70 ,  G06F19/708

Abstract: Systems and methods for processing sensor data and end of life detection are provided. In some embodiments, a method for determining the end of life of a continuous analyte sensor includes evaluating a plurality of risk factors using an end of life function to determine an end of life status of the sensor and providing an output related to the end of life status of the sensor. The plurality of risk factors may be selected from the list including the number of days the sensor has been in use, whether there has been a decrease in signal sensitivity, whether there is a predetermined noise pattern, whether there is a predetermined oxygen concentration pattern, and error between reference BG values and EGV sensor values.

公开(公告)号：US09741139B2

公开(公告)日：2017-08-22

申请号：US13963416

申请日：2013-08-09

Applicant: DexCom, Inc.

Inventor： Apurv Ullas Kamath ,  Richard C. Yang ,  Jacob S. Leach ,  Nelson Quintana

IPC: A61M31/00 ,  G06T11/20 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1486 ,  A61M5/315 ,  A61M5/24 ,  A61M5/00 ,  A61M5/142 ,  A61M5/172 ,  A61M5/31

CPC classification number: G06T11/206 ,  A61B5/0002 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/14865 ,  A61B5/4839 ,  A61B2560/0406 ,  A61B2560/0431 ,  A61B2560/0443 ,  A61M5/003 ,  A61M5/14244 ,  A61M5/1723 ,  A61M5/24 ,  A61M5/3129 ,  A61M5/31525 ,  A61M2205/3569 ,  A61M2205/505 ,  A61M2209/086 ,  G06F19/00

Abstract: An integrated system for the monitoring and treating diabetes is provided, including an integrated receiver/hand-held medicament injection pen, including electronics, for use with a continuous glucose sensor. In some embodiments, the receiver is configured to receive continuous glucose sensor data, to calculate a medicament therapy (e.g., via the integrated system electronics) and to automatically set a bolus dose of the integrated hand-held medicament injection pen, whereby the user can manually inject the bolus dose of medicament into the host. In some embodiments, the integrated receiver and hand-held medicament injection pen are integrally formed, while in other embodiments they are detachably connected and communicated via mutually engaging electrical contacts and/or via wireless communication.

公开(公告)号：US09700253B2

公开(公告)日：2017-07-11

申请号：US13796642

申请日：2013-03-12

Applicant: DexCom, Inc.

Inventor： Michael J. Estes ,  Stephen J. Vanslyke ,  Apurv Ullas Kamath ,  Thomas A. Peyser ,  Lucas Bohnett ,  Aarthi Mahalingam ,  Arturo Garcia ,  Peter C. Simpson ,  Anna Leigh Rack-Gomer ,  Sebastian Bohm

IPC: G01D3/02 ,  A61B5/1495 ,  A61B5/145 ,  G06F19/00 ,  A61B5/00

CPC classification number: A61B5/1495 ,  A61B5/0031 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/7203 ,  A61B2560/0223 ,  A61B2562/02 ,  G01D3/022 ,  G06F19/3468

Abstract: Systems and methods for applying time-dependent algorithmic compensation functions to data output from a continuous analyte sensor. Some embodiments determine a time since sensor implantation and/or whether a newly initialized sensor has been used previously.

公开(公告)号：US20170076068A1

公开(公告)日：2017-03-16

申请号：US15362571

申请日：2016-11-28

Applicant: DexCom, Inc.

Inventor： John Michael Dobbles ,  Apurv Ullas Kamath ,  Aarthi Mahalingam ,  James H. Brauker

IPC: G06F19/00 ,  A61M5/20 ,  A61M35/00 ,  A61M11/00 ,  A61M5/142 ,  A61M5/172 ,  A61M15/00

CPC classification number: A61M5/1723 ,  A61B5/0031 ,  A61B5/14532 ,  A61B5/14546 ,  A61M5/003 ,  A61M5/14244 ,  A61M5/14276 ,  A61M5/178 ,  A61M5/20 ,  A61M5/30 ,  A61M11/00 ,  A61M15/00 ,  A61M15/0065 ,  A61M15/0068 ,  A61M15/008 ,  A61M15/0083 ,  A61M35/00 ,  A61M2005/14296 ,  A61M2205/3569 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2205/587 ,  A61M2205/8206 ,  A61M2230/201 ,  G06F19/00 ,  G06F19/3468 ,  G16H40/63

Abstract: Systems and methods for integrating a continuous glucose sensor 12, including a receiver 14, a medicament delivery device 16, a controller module, and optionally a single point glucose monitor 18 are provided. Integration may be manual, semi-automated and/or fully automated.

Abstract translation: 提供了用于集成包括接收器14，药物输送装置16，控制器模块和任选的单点葡萄糖监测器18的连续葡萄糖传感器12的系统和方法。 集成可以是手动，半自动化和/或完全自动化。

公开(公告)号：US20170071512A1

公开(公告)日：2017-03-16

申请号：US15261818

申请日：2016-09-09

Applicant: DexCom, Inc.

Inventor： Arturo Garcia ,  Peter C. Simpson ,  Apurv Ullas Kamath ,  Naresh C. Bhavaraju ,  Stephen J. Vanslyke

IPC: A61B5/1495 ,  A61B5/00 ,  A61B5/145

CPC classification number: A61B5/0031 ,  A61B5/1118 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/1495 ,  A61B5/7246 ,  A61B5/743 ,  A61B2560/0223 ,  A61B2560/0228

Abstract: Systems and methods are provided to calibrate an analyte concentration sensor within a biological system, generally using only a signal from the analyte concentration sensor. For example, at a steady state, the analyte concentration value within the biological system is known, and the same may provide a source for calibration. Similar techniques may be employed with slow-moving averages. Variations are disclosed.

Abstract translation: 提供了系统和方法来校准生物系统内的分析物浓度传感器，通常仅使用来自分析物浓度传感器的信号。 例如，在稳定状态下，生物系统内的分析物浓度值是已知的，并且相同的可以提供用于校准的源。 慢移平均值也可采用类似的技术。 公开了变化。

公开(公告)号：US20160328991A1

公开(公告)日：2016-11-10

申请号：US15148976

申请日：2016-05-06

Applicant: DexCom, Inc.

Inventor： Peter C. Simpson ,  Robert J. Boock ,  David DeRenzy ,  Laura J. Dunn ,  Matthew Lawrence Johnson ,  Katherine Yerre Koehler ,  Apurv Ullas Kamath ,  Andrew Attila Pal ,  David Price ,  Eli Reihman ,  Mark Wu

IPC: G09B19/00 ,  A61B5/145

Abstract: Provided are systems and methods using which users may learn and become familiar with the effects of various aspects of their lifestyle on their health, e.g., users may learn about how food and/or exercise affects their glucose level and other physiological parameters, as well as overall health. In some cases the user selects a program to try; in other cases, a computing environment embodying the system suggests programs to try, including on the basis of pattern recognition, i.e., by the computing environment determining how a user could improve a detected pattern in some way. In this way, users such as type II diabetics or even users who are only prediabetic or non-diabetic may learn healthy habits to benefit their health.

公开(公告)号：US09463277B2

公开(公告)日：2016-10-11

申请号：US14144360

申请日：2013-12-30

Applicant: DexCom, Inc.

Inventor： John Michael Dobbles ,  Apurv Ullas Kamath ,  Aarthi Mahalingam ,  James H. Brauker

IPC: A61M5/172 ,  A61B5/145 ,  A61M5/142 ,  G06F19/00 ,  A61B5/00 ,  A61M5/00 ,  A61M5/178 ,  A61M5/30 ,  A61M11/00 ,  A61M15/00

CPC classification number: A61M5/1723 ,  A61B5/0031 ,  A61B5/14532 ,  A61B5/14546 ,  A61M5/003 ,  A61M5/14244 ,  A61M5/14276 ,  A61M5/178 ,  A61M5/20 ,  A61M5/30 ,  A61M11/00 ,  A61M15/00 ,  A61M15/0065 ,  A61M15/0068 ,  A61M15/008 ,  A61M15/0083 ,  A61M35/00 ,  A61M2005/14296 ,  A61M2205/3569 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2205/587 ,  A61M2205/8206 ,  A61M2230/201 ,  G06F19/00 ,  G06F19/3468 ,  G16H40/63

Abstract: Systems and methods for integrating a continuous glucose sensor 12, including a receiver 14, a medicament delivery device 16, a controller module, and optionally a single point glucose monitor 18 are provided. Integration may be manual, semi-automated and/or fully automated.

公开(公告)号：US20160106350A1

公开(公告)日：2016-04-21

申请号：US14975444

申请日：2015-12-18

Applicant: DexCom, Inc.

Inventor： Naresh C. Bhavaraju ,  Michael A. Bloom ,  Leif N. Bowman ,  Alexandra Lynn Carlton ,  Katherine Yerre Koehler ,  Hari Hampapuram ,  Lauren Hruby Jepson ,  Jonathan Hughes ,  Apurv Ullas Kamath ,  Anna Leigh Rack-Gomer ,  Peter C. Simpson ,  Stephen J. Vanslyke

IPC: A61B5/145 ,  A61M5/172 ,  A61B5/00

CPC classification number: A61B5/14532 ,  A61B5/0002 ,  A61B5/0004 ,  A61B5/14503 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/1486 ,  A61B5/1495 ,  A61B5/6898 ,  A61B5/72 ,  A61B5/7221 ,  A61B5/7275 ,  A61B5/7282 ,  A61B5/742 ,  A61B5/7435 ,  A61B5/746 ,  A61B5/7475 ,  A61B2560/0223 ,  A61B2560/0487 ,  A61M5/1723 ,  A61M2230/005 ,  A61M2230/201 ,  G16H40/40 ,  G16H40/63 ,  Y02A90/26

Abstract: Systems and methods described provide dynamic and intelligent ways to change the required level of user interaction during use of a monitoring device. The systems and methods generally relate to real time switching between a first or initial mode of user interaction and a second or new mode of user interaction. In some cases, the switching will be automatic and transparent to the user, and in other cases user notification may occur. The mode switching generally affects the user's interaction with the device, and not just internal processing. The mode switching may relate to calibration modes, data transmission modes, control modes, or the like.

Abstract translation: 所描述的系统和方法提供了动态和智能的方式，以便在监视设备的使用过程中改变所需的用户交互级别。 系统和方法通常涉及用户交互的第一或初始模式与第二或新的用户交互模式之间的实时切换。 在某些情况下，切换将对用户自动和透明，在其他情况下，可能会发生用户通知。 模式切换通常影响用户与设备的交互，而不仅仅是内部处理。 模式切换可以涉及校准模式，数据传输模式，控制模式等。

公开(公告)号：US20150351672A1

公开(公告)日：2015-12-10

申请号：US14717965

申请日：2015-05-20

Applicant: DexCom, Inc.

Inventor： Stephen J. Vanslyke ,  Naresh C. Bhavaraju ,  Sebastian Böhm ,  Leif N. Bowman ,  Michael J. Estes ,  Arturo Garcia ,  Apurv Ullas Kamath ,  Andrew Attila Pal ,  Thomas A. Peyser ,  Anna Leigh Rack-Gomer ,  Daiting Rong ,  Disha B. Sheth ,  Peter C. Simpson ,  Dmytro Sokolovsky

IPC: A61B5/1495 ,  A61B5/01 ,  A61B5/1486 ,  A61B5/145 ,  A61B5/053 ,  A61B5/00 ,  A61B5/11

CPC classification number: A61B5/1495 ,  A61B5/01 ,  A61B5/053 ,  A61B5/1118 ,  A61B5/14532 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/14865 ,  A61B5/4833 ,  A61B5/4839 ,  A61B5/4848 ,  A61B5/4866 ,  A61B5/6898 ,  A61B5/7203 ,  A61B5/7221 ,  A61B5/7275 ,  A61B5/7278 ,  A61B5/7282 ,  A61B5/742 ,  A61B5/746 ,  A61B2560/0247 ,  A61B2560/0252 ,  A61B2560/0276 ,  A61B2560/0475 ,  A61B2562/0247 ,  A61M5/1723 ,  A61M2205/3584 ,  A61M2205/3592 ,  A61M2205/50 ,  A61M2205/52 ,  A61M2230/201 ,  G06F19/00

Abstract: Systems and methods disclosed here provide ways to discriminate fault types encountered in analyte sensors and systems and further provide ways to process such discriminated faults responsively based on sensor data, clinical context information, and other data about the patient or patient's environment. The systems and methods thus employ clinical context in detecting and/or responding to errors or faults associated with an analyte sensor system, and discriminating the type of fault, and its root cause, particularly as fault dynamics can appear similar to the dynamics of physiological systems, emphasizing the importance of discriminating the fault and providing appropriate responsive processing. Thus, the disclosed systems and methods consider the context of the patient's health condition or state in determining how to respond to the fault.

公开(公告)号：US20150351671A1

公开(公告)日：2015-12-10

申请号：US14717904

申请日：2015-05-20

Applicant: DexCom, Inc.

Inventor： Stephen J. Vanslyke ,  Naresh C. Bhavaraju ,  Sebastian Böhm ,  Leif N. Bowman ,  Michael J. Estes ,  Arturo Garcia ,  Apurv Ullas Kamath ,  Andrew Attila Pal ,  Thomas A. Peyser ,  Anna Leigh Rack-Gomer ,  Daiting Rong ,  Disha B. Sheth ,  Peter C. Simpson ,  Dmytro Sokolovsky

IPC: A61B5/1495 ,  A61B5/145 ,  A61M5/172 ,  A61B5/053 ,  A61B5/00 ,  A61B5/1473 ,  A61B5/01

CPC classification number: A61B5/1495 ,  A61B5/01 ,  A61B5/053 ,  A61B5/1118 ,  A61B5/14532 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/14865 ,  A61B5/4833 ,  A61B5/4839 ,  A61B5/4848 ,  A61B5/4866 ,  A61B5/6898 ,  A61B5/7203 ,  A61B5/7221 ,  A61B5/7275 ,  A61B5/7278 ,  A61B5/7282 ,  A61B5/742 ,  A61B5/746 ,  A61B2560/0247 ,  A61B2560/0252 ,  A61B2560/0276 ,  A61B2560/0475 ,  A61B2562/0247 ,  A61M5/1723 ,  A61M2205/3584 ,  A61M2205/3592 ,  A61M2205/50 ,  A61M2205/52 ,  A61M2230/201 ,  G06F19/00

Abstract: Systems and methods disclosed here provide ways to discriminate fault types encountered in analyte sensors and systems and further provide ways to process such discriminated faults responsively based on sensor data, clinical context information, and other data about the patient or patient's environment. The systems and methods thus employ clinical context in detecting and/or responding to errors or faults associated with an analyte sensor system, and discriminating the type of fault, and its root cause, particularly as fault dynamics can appear similar to the dynamics of physiological systems, emphasizing the importance of discriminating the fault and providing appropriate responsive processing. Thus, the disclosed systems and methods consider the context of the patient's health condition or state in determining how to respond to the fault.