利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

29 条记录 (耗时 0.024 秒)

    Coated implants and related methods
    22.
    发明授权
    Coated implants and related methods 有权
    涂层植入物及相关方法

    公开(公告)号：US09051639B2

    公开(公告)日：2015-06-09

    申请号：US13619319

    申请日：2012-09-14

    申请人： Bryan McEntire ,  Ramaswamy Lakshminarayanan

    发明人： Bryan McEntire ,  Ramaswamy Lakshminarayanan

    IPC分类号： A61F2/30 ,  C23C14/06 ,  A61F2/32 ,  C23C14/48 ,  A61L27/10 ,  A61L27/30

    CPC分类号： C23C14/0605 ,  A61F2/32 ,  A61F2002/30695 ,  A61F2002/3098 ,  A61F2002/30981 ,  A61F2310/00179 ,  A61F2310/0058 ,  A61F2310/00856 ,  A61L27/10 ,  A61L27/303 ,  A61L27/306 ,  A61L2420/02 ,  A61L2430/02 ,  C23C14/0652 ,  C23C14/48 ,  F04C2270/0421

    摘要： Methods, apparatus, and systems for improving the performance of articulating prostheses. Some embodiments may comprise a first component comprising a first articulating surface and a second component comprising a second articulating surface configured for articulating with the first articulating surface. One or both of the first and second components may comprise a silicon nitride ceramic material. One or both of the first and second articulating surfaces may comprise a coating that is configured to accomplish at least one of increasing the hardness of the first articulating interface surface, reducing the coefficient of friction between the first and second articulating surfaces, decreasing the effects of wearing between the first and second articulating surfaces, and decreasing the intensity of audible noises produced by the endoprosthesis resulting from articulation between the first and second articulating surfaces during use.

    摘要翻译： 用于改善关节假体的性能的方法，装置和系统。 一些实施例可以包括第一部件，其包括第一铰接表面和第二部件，第二部件包括构造成与第一铰接表面铰接的第二铰接表面。 第一和第二组分中的一个或两个可以包括氮化硅陶瓷材料。 第一和第二关节表面中的一个或两个可以包括被配置成实现增加第一铰接界面的硬度，降低第一和第二铰接表面之间的摩擦系数中的至少一个的涂层， 佩戴在第一和第二铰接表面之间，并且减少由使用期间在第一和第二铰接表面之间的铰接导致的内置假体产生的可听见的噪声的强度。

    TOTAL DISC IMPLANT
    23.
    发明申请
    TOTAL DISC IMPLANT 有权
    总盘移植

    公开(公告)号：US20080033563A1

    公开(公告)日：2008-02-07

    申请号：US11858016

    申请日：2007-09-19

    申请人： Ashok Khandkar ,  Darrel Brodke ,  Ramaswamy Lakshminarayanan

    发明人： Ashok Khandkar ,  Darrel Brodke ,  Ramaswamy Lakshminarayanan

    IPC分类号： A61F2/44 ,  A61B17/58

    CPC分类号： A61F2/4425 ,  A61F2/30767 ,  A61F2002/30224 ,  A61F2002/30301 ,  A61F2002/30365 ,  A61F2002/30604 ,  A61F2002/30616 ,  A61F2002/30878 ,  A61F2002/30934 ,  A61F2002/443 ,  A61F2220/0033 ,  A61F2230/0069 ,  A61F2230/0095 ,  A61F2310/00023 ,  A61F2310/00029 ,  A61F2310/00317 ,  Y10S606/907

    摘要： A total disc implant (TDI) is provided for total replacement of a spinal disc or discs in a human patient or other mammal, wherein the TDI is designed to maintain a substantially full range of natural motion (ROM) following implantation. The TDI generally comprises, in one preferred form, upper and lower end plates for affixation to adjacent vertebral bodies, with an intervening insert disposed therebetween. The end plates each include elongated part-cylindrical surfaces oriented generally perpendicular to each other, with one of said surfaces extending in an anterior-posterior direction and the other extending in a medial-lateral direction. The intervening insert defines concave upper and lower part-cylindrical seats oriented for respectively engaging these part-cylindrical surfaces, wherein these part-cylindrical seats are defined by offset radii to include a somewhat flattened central base region merging smoothly with upwardly curving radiused sides.

    摘要翻译： 全盘植入物（TDI）被提供用于人类患者或其他哺乳动物中的脊椎盘或椎间盘的完全替换，其中TDI被设计成在植入后保持基本上全部的自然运动范围（ROM）。 在一个优选形式中，TDI通常包括用于固定到相邻椎体的上端板和下端板，其间设置插入插入件。 端板各自包括大致垂直于彼此定向的细长部分圆柱形表面，其中一个表面沿前后方向延伸，另一个延伸在内侧方向上。 中间插入件限定凹入的上部和下部圆柱形座，其定位成分别接合这些部分圆柱形表面，其中这些部分圆柱形座由偏移半径限定，以包括平滑地与向上弯曲的圆弧边合并的稍微平坦化的中心基部区域。

    Osteoconductive spinal fixation system
    24.
    发明申请
    Osteoconductive spinal fixation system 审中-公开
    骨诱导性脊柱固定系统

    公开(公告)号：US20060276788A1

    公开(公告)日：2006-12-07

    申请号：US11139126

    申请日：2005-05-26

    申请人： Bret Berry ,  Ashok Khandkar ,  Ramaswamy Lakshminarayanan

    发明人： Bret Berry ,  Ashok Khandkar ,  Ramaswamy Lakshminarayanan

    IPC分类号： A61F2/30

    CPC分类号： A61B17/863 ,  A61B17/7005 ,  A61B17/7011 ,  A61B17/7037 ,  A61B17/7059 ,  A61B17/866 ,  A61B2017/00004 ,  A61F2/0077 ,  A61F2310/00592 ,  A61F2310/00796

    摘要： An improved spinal fixation system is provided for human implantation, including a set of screws with interconnecting rods for implantation into the pedicle and between two adjacent vertebrae or a plate with screws for fixating two adjacent vertebrae. The screws, rods, and plates include a substrate portion of high strength biocompatible material and a controlled porosity analogous to natural bone. The substrate portion may be coated with a bio-active surface coating material such as hydroxyapatite or a calcium phosphate to promote bone ingrowth and enhanced bone fusion. Upon implantation, the fixation system provides a desired combination of mechanical strength together with osteoconductivity and bio-activity to promote bone ingrowth and fusion, as well as radiolucency for facilitated post-operative monitoring. The fixation system may additionally carry one or more natural or synthetic therapeutic agents for further promoting bone ingrowth and fusion.

    摘要翻译： 提供了一种改进的脊柱固定系统，用于人类植入，包括一组螺钉，其具有用于植入椎弓根的相互连接的杆和两个相邻椎骨之间的螺钉或具有用于固定两个相邻椎骨的螺钉的板。 螺钉，杆和板包括高强度生物相容性材料的基底部分和类似于天然骨的受控孔隙。 衬底部分可以涂覆有生物活性表面涂层材料，例如羟基磷灰石或磷酸钙，以促进骨向内生长和增强骨融合。 植入后，固定系统提供机械强度与骨传导性和生物活性的期望组合，以促进骨向内生长和融合，以及便于手术后监测的放射性。 固定系统可另外携带一种或多种天然或合成治疗剂，用于进一步促进骨向内生长和融合。

    Metal-ceramic composite articulation
    25.
    发明申请
    Metal-ceramic composite articulation 有权
    金属陶瓷复合铰接

    公开(公告)号：US20050107888A1

    公开(公告)日：2005-05-19

    申请号：US11020424

    申请日：2004-12-21

    申请人： Ashok Khandkar ,  Aaron Hofmann ,  Ramaswamy Lakshminarayanan

    发明人： Ashok Khandkar ,  Aaron Hofmann ,  Ramaswamy Lakshminarayanan

    IPC分类号： A61L27/04 ,  A61L27/10 ,  A61L27/42 ,  A61F2/30

    CPC分类号： A61L27/045 ,  A61F2/32 ,  A61F2/34 ,  A61F2002/3611 ,  A61F2310/00317 ,  A61L27/10 ,  A61L27/42 ,  A61L27/427 ,  A61L2430/24

    摘要： A ceramic-metal composite articulation is provided with substantial elimination of wear debris, wherein a ceramic material is provided with superior mechanical properties tailored for articulating with ceramic articulations having high flexural strength (greater than about 700 MPa), high fracture toughness (greater than about 7 MPam1/2) and a high Weibull modulus (greater than about 20), in comparison with presently available bio-ceramics such as alumina or zirconia. The mechanical property enhancement enables ceramic materials with greater reliability and significantly reduced in-vivo fracture risk to be obtained. Preliminary in-vitro wear performance, to several million cycles using established test protocols, of head/cup components in a prosthetic hip joint made from these ceramics also demonstrates the ultra low wear characteristics. These material properties substantially eliminate polyethylene (PE) wear debris mediated implant failures by offering an optimal combination of bio-mechanical safety and reliability with ultra low wear performance.

    摘要翻译： 陶瓷 - 金属复合铰链提供了大量消除磨损碎屑，其中陶瓷材料具有优良的机械性能，适合于与具有高弯曲强度（大于约700MPa），高断裂韧性（大于约700MPa） 与目前可获得的生物陶瓷如氧化铝或氧化锆相比，具有较高的威布尔模量（大于约20）。 机械性能的提高使陶瓷材料具有更高的可靠性和显着降低的体内断裂风险。 由这些陶瓷制成的假体髋关节中的头部/杯部件的初步体外磨损性能，使用已建立的测试方案达数百万次循环，也表现出超低磨损特性。 通过提供生物机械安全性和可靠性与超低磨损性能的最佳组合，这些材料性质基本上消除了聚乙烯（PE）磨损碎片介导的植入物失效。

    Metal-ceramic composite articulation
    26.
    发明申请
    Metal-ceramic composite articulation 有权
    金属陶瓷复合铰接

    公开(公告)号：US20050090903A1

    公开(公告)日：2005-04-28

    申请号：US10987415

    申请日：2004-11-12

    申请人： Ashok Khandkar ,  Aaron Hofmann ,  Ramaswamy Lakshminarayanan

    发明人： Ashok Khandkar ,  Aaron Hofmann ,  Ramaswamy Lakshminarayanan

    IPC分类号： A61L27/04 ,  A61L27/10 ,  A61L27/42 ,  A61F2/32 ,  A61F2/28 ,  A61F2/30

    CPC分类号： A61L27/045 ,  A61F2/32 ,  A61F2/34 ,  A61F2002/3611 ,  A61F2310/00317 ,  A61L27/10 ,  A61L27/42 ,  A61L27/427 ,  A61L2430/24

    摘要： A ceramic-metal composite articulation is provided with substantial elimination of wear debris, wherein a ceramic material is provided with superior mechanical properties tailored for articulating with ceramic articulations having high flexural strength (greater than about 700 MPa), high fracture toughness (greater than about 7 MPam1/2) and a high Weibull modulus (greater than about 20), in comparison with presently available bio-ceramics such as alumina or zirconia. The mechanical property enhancement enables ceramic materials with greater reliability and significantly reduced in-vivo fracture risk to be obtained. Preliminary in-vitro wear performance, to several million cycles using established test protocols, of head/cup components in a prosthetic hip joint made from these ceramics also demonstrates the ultra low wear characteristics. These material properties substantially eliminate PE wear debris mediated implant failures by offering an optimal combination of bio-mechanical safety and reliability with ultra low wear performance.

    摘要翻译： 陶瓷 - 金属复合铰链提供了大量消除磨损碎屑，其中陶瓷材料具有优良的机械性能，适合于与具有高弯曲强度（大于约700MPa），高断裂韧性（大于约700MPa） 与目前可获得的生物陶瓷如氧化铝或氧化锆相比，具有较高的威布尔模量（大于约20）。 机械性能的提高使陶瓷材料具有更高的可靠性和显着降低的体内断裂风险。 由这些陶瓷制成的假体髋关节中的头部/杯部件的初步体外磨损性能，使用已建立的测试方案达数百万次循环，也表现出超低磨损特性。 通过提供生物机械安全性和可靠性与超低磨损性能的最佳组合，这些材料性质基本上消除了PE磨损碎片介导的植入物失效。

    COATED IMPLANTS AND RELATED METHODS
    27.
    发明申请
    COATED IMPLANTS AND RELATED METHODS 有权
    涂层植入物及相关方法

    公开(公告)号：US20130073050A1

    公开(公告)日：2013-03-21

    申请号：US13619319

    申请日：2012-09-14

    申请人： Bryan McEntire ,  Ramaswamy Lakshminarayanan

    发明人： Bryan McEntire ,  Ramaswamy Lakshminarayanan

    IPC分类号： A61F2/30 ,  C23C14/48 ,  A61F2/32

    CPC分类号： C23C14/0605 ,  A61F2/32 ,  A61F2002/30695 ,  A61F2002/3098 ,  A61F2002/30981 ,  A61F2310/00179 ,  A61F2310/0058 ,  A61F2310/00856 ,  A61L27/10 ,  A61L27/303 ,  A61L27/306 ,  A61L2420/02 ,  A61L2430/02 ,  C23C14/0652 ,  C23C14/48 ,  F04C2270/0421

    摘要： Methods, apparatus, and systems for improving the performance of articulating prostheses. Some embodiments may comprise a first component comprising a first articulating surface and a second component comprising a second articulating surface configured for articulating with the first articulating surface. One or both of the first and second components may comprise a silicon nitride ceramic material. One or both of the first and second articulating surfaces may comprise a coating that is configured to accomplish at least one of increasing the hardness of the first articulating interface surface, reducing the coefficient of friction between the first and second articulating surfaces, decreasing the effects of wearing between the first and second articulating surfaces, and decreasing the intensity of audible noises produced by the endoprosthesis resulting from articulation between the first and second articulating surfaces during use.

    摘要翻译： 用于改善关节假体的性能的方法，装置和系统。 一些实施例可以包括第一部件，其包括第一铰接表面和第二部件，第二部件包括构造成与第一铰接表面铰接的第二铰接表面。 第一和第二组分中的一个或两个可以包括氮化硅陶瓷材料。 第一和第二关节表面中的一个或两个可以包括被配置成实现增加第一铰接界面的硬度，降低第一和第二铰接表面之间的摩擦系数中的至少一个的涂层， 佩戴在第一和第二铰接表面之间，并且减少由使用期间在第一和第二铰接表面之间的铰接导致的内置假体产生的可听见的噪声的强度。