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公开(公告)号：US20190315824A1
公开(公告)日：2019-10-17
申请号：US16438735
申请日：2019-06-12
Applicant: ModernaTX, Inc.
Inventor： Antonin DE FOUGEROLLES , Justin GUILD
IPC: C07K14/535 , A61K48/00 , A61K47/54 , A61K31/7088 , A61K38/48 , C07K14/745 , C07K16/28 , C07K16/32 , C12N9/02 , C12N9/64 , A61K38/19 , A61K38/21 , A61K38/36 , A61K38/44 , A61K39/395 , C07K14/475 , C07K14/505 , C07K14/525 , C07K14/56 , C07K14/565 , C07K14/75 , A61K47/10 , A61K38/18 , A61K38/17 , A61K9/14 , C07K14/47 , C12N15/85 , A61K9/50 , A61K9/127 , C12N15/88 , C07K19/00
Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
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公开(公告)号：US20190240351A1
公开(公告)日：2019-08-08
申请号：US15789138
申请日：2017-10-20
Applicant: ModernaTX, Inc.
Inventor： Stephane BANCEL , Tirtha CHAKRABORTY , Antonin DE FOUGEROLLES , Sayda M. ELBASHIR , Jeff Lynn ELLSWORTH , Kenechi EJEBE , Justin GUILD , Matthias JOHN , Paul HATALA , Atanu ROY , Jason P. SCHRUM , Susan WHORISKEY , Kristy M. WOOD
IPC: A61K48/00 , C07K14/535 , C07K14/47 , C07K14/515 , A61K9/127 , C12N9/64 , A61K31/7115 , A61K47/54 , A61K9/51 , A61K9/14 , C12N15/87 , C12N15/85 , C12N9/00 , C07K14/705 , C07K14/62 , C07K14/505 , C07K14/485 , C07K14/435 , A61K38/45 , A61K38/17 , A61K38/48 , C07K14/525 , C07K14/56 , C07K16/00 , C12P21/00 , A61K38/18 , A61K38/19 , A61K38/21 , C12P13/04 , C12N15/52 , C12N15/11 , C12N9/88 , C12N9/42 , C12N9/24 , C12N9/16 , C12N9/10 , C07K14/005
CPC classification number: A61K48/0066 , A61K9/1271 , A61K9/145 , A61K9/5123 , A61K9/5146 , A61K9/5153 , A61K31/7115 , A61K38/00 , A61K38/17 , A61K38/177 , A61K38/1816 , A61K38/1891 , A61K38/191 , A61K38/193 , A61K38/212 , A61K38/45 , A61K38/4846 , A61K47/543 , A61K48/0033 , A61K48/005 , A61K48/0075 , C07H21/02 , C07K14/005 , C07K14/435 , C07K14/43595 , C07K14/47 , C07K14/4705 , C07K14/4713 , C07K14/4723 , C07K14/4746 , C07K14/475 , C07K14/485 , C07K14/495 , C07K14/505 , C07K14/515 , C07K14/525 , C07K14/535 , C07K14/5418 , C07K14/56 , C07K14/61 , C07K14/62 , C07K14/705 , C07K14/745 , C07K16/00 , C07K16/2863 , C07K16/2887 , C07K16/40 , C12N9/0069 , C12N9/0091 , C12N9/1051 , C12N9/1241 , C12N9/16 , C12N9/2402 , C12N9/2445 , C12N9/6435 , C12N9/6437 , C12N9/644 , C12N9/6443 , C12N9/6451 , C12N9/88 , C12N9/93 , C12N15/11 , C12N15/52 , C12N15/85 , C12N15/87 , C12P13/04 , C12P21/00 , C12P21/005 , C12Y113/12007 , C12Y116/03001 , C12Y207/07012 , C12Y304/21007 , C12Y304/21022 , C12Y304/21027 , C12Y403/02001 , C12Y603/02019 , Y02A50/401 , Y02A50/411 , Y02A50/414 , Y02A50/415 , Y02A50/423 , Y02A50/463 , Y02A50/491
Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
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23.发明申请公开(公告)号：US20180086807A1
公开(公告)日：2018-03-29
申请号：US15440523
申请日：2017-02-23
Applicant: ModernaTX, Inc.
Inventor： Stephane BANCEL , Tirtha CHAKRABORTY , Antonin DE FOUGEROLLES , Sayda M. ELBASHIR , Matthias JOHN , Atanu ROY , Susan WHORISKEY , Kristy M. WOOD , Paul HATALA , Jason P. SCHRUM , Kenechi EJEBE , Jeff Lynn ELLSWORTH , Justin GUILD
IPC: C07K14/535 , A61K9/127 , C12N15/88 , C12N15/85 , C12N9/64 , C12N9/02 , C07K19/00 , C07K16/32 , C07K16/28 , C07K14/75 , C07K14/745 , C07K14/565 , C07K14/56 , C07K14/525 , C07K14/505 , C07K14/475 , C07K14/47 , A61K48/00 , A61K47/10 , A61K39/395 , A61K38/48 , A61K38/44 , A61K38/36 , A61K38/21 , A61K38/19 , A61K38/18 , A61K38/17 , A61K31/7088 , A61K9/50 , A61K9/14 , A61K9/00
CPC classification number: C07K14/535 , A61K9/0019 , A61K9/1271 , A61K9/1272 , A61K9/1277 , A61K9/14 , A61K9/5031 , A61K31/7088 , A61K38/1767 , A61K38/1816 , A61K38/1866 , A61K38/191 , A61K38/193 , A61K38/212 , A61K38/215 , A61K38/36 , A61K38/363 , A61K38/44 , A61K38/4833 , A61K38/4846 , A61K39/3955 , A61K47/10 , A61K47/54 , A61K47/542 , A61K48/00 , A61K48/0033 , A61K48/0066 , A61K48/0075 , C07K14/47 , C07K14/475 , C07K14/505 , C07K14/525 , C07K14/56 , C07K14/565 , C07K14/745 , C07K14/75 , C07K16/2887 , C07K16/32 , C07K19/00 , C12N9/0069 , C12N9/644 , C12N15/85 , C12N15/88 , C12N2840/00 , C12Y113/12007 , C12Y304/21005 , C12Y304/21022
Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
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24.发明申请公开(公告)号：US20180002393A1
公开(公告)日：2018-01-04
申请号：US15425813
申请日：2017-02-06
Applicant: ModernaTX, Inc.
Inventor： Stephane BANCEL , Tirtha CHAKRABORTY , Antonin DE FOUGEROLLES , Sayda M. ELBASHIR , Matthias JOHN , Atanu ROY , Susan WHORISKEY , Kristy M. WOOD , Paul HATALA , Jason P. SCHRUM , Kenechi EJEBE , Jeff Lynn ELLSWORTH , Justin GUILD
IPC: C07K14/535 , C12N15/88 , C12N15/85 , C12N9/64 , C12N9/02 , C07K19/00 , C07K16/32 , C07K16/28 , C07K14/75 , C07K14/745 , C07K14/565 , C07K14/56 , C07K14/525 , C07K14/505 , C07K14/475 , C07K14/47 , A61K48/00 , A61K47/60 , A61K47/10 , A61K39/395 , A61K38/48 , A61K38/44 , A61K38/36 , A61K38/21 , A61K38/19 , A61K38/18 , A61K38/17 , A61K31/7088 , A61K9/50 , A61K9/14 , A61K9/127 , A61K9/00
CPC classification number: C07K14/535 , A61K9/0019 , A61K9/0043 , A61K9/1271 , A61K9/1272 , A61K9/1277 , A61K9/14 , A61K9/145 , A61K9/5031 , A61K31/7088 , A61K31/7115 , A61K38/1767 , A61K38/1816 , A61K38/1866 , A61K38/191 , A61K38/193 , A61K38/212 , A61K38/215 , A61K38/36 , A61K38/363 , A61K38/44 , A61K38/4833 , A61K38/4846 , A61K39/3955 , A61K47/10 , A61K47/60 , A61K48/00 , A61K48/0033 , A61K48/0066 , A61K48/0075 , C07K14/47 , C07K14/475 , C07K14/505 , C07K14/525 , C07K14/56 , C07K14/565 , C07K14/745 , C07K14/75 , C07K16/2887 , C07K16/32 , C07K19/00 , C12N9/0069 , C12N9/644 , C12N15/85 , C12N15/88 , C12N2840/00 , C12Y113/12007 , C12Y304/21005 , C12Y304/21022 , A61K2300/00
Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of oncology-related polynucleotides, oncology-related primary transcripts and oncology-related mmRNA molecules.
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公开(公告)号：US20170028085A1
公开(公告)日：2017-02-02
申请号：US15294339
申请日：2016-10-14
Applicant: ModernaTX, Inc.
Inventor： Stephane BANCEL , Tirtha CHAKRABORTY , Antonin DE FOUGEROLLES , Sayda M. ELBASHIR , Matthias JOHN , Atanu ROY , Susan WHORISKEY , Kristy M. Wood , Paul HATALA , Jason P. SCHRUM , Kenechi EJEBE , Jeff Lynn ELLSWORTH , Justin GUILD , Ron WEISS
IPC: A61K48/00 , A61K9/50 , C07K14/535 , A61K38/19 , A61K38/48 , C07K14/505 , A61K38/18 , C07K14/525 , C07K14/565 , A61K38/21 , C07K16/32 , A61K39/395 , C07K16/28 , C07K14/475 , A61K38/44 , C07K14/56 , C07K14/745 , A61K38/36 , C07K14/75 , C12N9/64 , C12N9/02 , A61K9/127
CPC classification number: C07K14/535 , A61K9/0019 , A61K9/1271 , A61K9/1272 , A61K9/1277 , A61K9/14 , A61K9/5031 , A61K31/7088 , A61K38/1767 , A61K38/1816 , A61K38/1866 , A61K38/191 , A61K38/193 , A61K38/212 , A61K38/215 , A61K38/36 , A61K38/363 , A61K38/44 , A61K38/4833 , A61K38/4846 , A61K39/3955 , A61K47/10 , A61K47/54 , A61K47/542 , A61K48/00 , A61K48/0033 , A61K48/0066 , A61K48/0075 , C07K14/47 , C07K14/475 , C07K14/505 , C07K14/525 , C07K14/56 , C07K14/565 , C07K14/745 , C07K14/75 , C07K16/2887 , C07K16/32 , C07K19/00 , C12N9/0069 , C12N9/644 , C12N15/85 , C12N15/88 , C12N2840/00 , C12Y113/12007 , C12Y304/21005 , C12Y304/21022
Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
Abstract translation: 本发明涉及用于制备，制造和治疗性使用多核苷酸，初级转录物和mmRNA分子的组合物和方法。
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Patent Agency Ranking
公开(公告)号：US20250090667A1
公开(公告)日：2025-03-20
申请号：US18820652
申请日：2024-08-30
Applicant: ModernaTX, Inc.
Inventor： Antonin DE FOUGEROLLES , Sayda M. ELBASHIR
IPC: A61K47/18 , A61K31/7088 , A61K31/7115 , A61K38/19 , A61K38/48 , A61K47/22 , A61K47/28 , A61K48/00 , C07K14/535 , C12N9/64 , C12N15/67 , C12N15/87
Abstract: Provided are formulations, compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein expression. Such compositions and methods include the delivery of biological moieties, and are useful for production of proteins.
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公开(公告)号：US20250090666A1
公开(公告)日：2025-03-20
申请号：US18820609
申请日：2024-08-30
Applicant: ModernaTX, Inc.
Inventor： Antonin DE FOUGEROLLES , Sayda M. ELBASHIR
IPC: A61K47/18 , A61K31/7088 , A61K31/7115 , A61K38/19 , A61K38/48 , A61K47/22 , A61K47/28 , A61K48/00 , C07K14/535 , C12N9/64 , C12N15/67 , C12N15/87
Abstract: Provided are formulations, compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein expression. Such compositions and methods include the delivery of biological moieties, and are useful for production of proteins.
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公开(公告)号：US20240409597A1
公开(公告)日：2024-12-12
申请号：US18543930
申请日：2023-12-18
Applicant: ModernaTX, Inc.
Inventor： Antonin DE FOUGEROLLES , Justin GUILD
IPC: C07K14/535 , A61K9/00 , A61K9/127 , A61K9/14 , A61K9/50 , A61K31/7088 , A61K38/17 , A61K38/18 , A61K38/19 , A61K38/21 , A61K38/36 , A61K38/44 , A61K38/48 , A61K39/395 , A61K47/10 , A61K47/54 , A61K48/00 , C07K14/47 , C07K14/475 , C07K14/505 , C07K14/525 , C07K14/56 , C07K14/565 , C07K14/745 , C07K14/75 , C07K16/28 , C07K16/32 , C07K19/00 , C12N9/02 , C12N9/64 , C12N15/85 , C12N15/88
Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
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公开(公告)号：US20240252645A1
公开(公告)日：2024-08-01
申请号：US18417715
申请日：2024-01-19
Applicant: ModernaTx, Inc.
Inventor： Antonin DE FOUGEROLLES , Sayda M. Elbashir
IPC: A61K47/18 , A61K31/7088 , A61K31/7115 , A61K38/19 , A61K38/48 , A61K47/22 , A61K47/28 , C07K14/535 , C12N9/64 , C12N15/67 , C12N15/87 , A61K48/00
CPC classification number: A61K47/18 , A61K31/7088 , A61K31/7115 , A61K38/193 , A61K38/4846 , A61K47/22 , A61K47/28 , C07K14/535 , C12N9/644 , C12N15/67 , C12N15/87 , A61K48/00 , C12N2310/335
Abstract: Provided are formulations, compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein expression. Such compositions and methods include the delivery of biological moieties, and are useful for production of proteins.
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公开(公告)号：US20230013773A1
公开(公告)日：2023-01-19
申请号：US17162061
申请日：2021-01-29
Applicant: ModernaTX, Inc.
Inventor： Stephen G. HOGE , Tirtha CHAKRABORTY , Joshua P. FREDERICK , Matthias JOHN , Antonin DE FOUGEROLLES
IPC: C07K14/47 , A61K48/00 , C12N15/85 , C12N15/113 , A61K31/7105 , A61K31/711
Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of signal-sensor polynucleotides, primary transcripts and mmRNA molecules.
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