公开(公告)号：US20140339146A1

公开(公告)日：2014-11-20

申请号：US14451524

申请日：2014-08-05

Applicant: EMD Millipore Corporation

Inventor： Joseph Almasian ,  Jeremy Perreault ,  Martin Szyk

IPC: B01D35/30 ,  B01D29/15

CPC classification number: B01D35/306 ,  B01D27/00 ,  B01D27/08 ,  B01D29/15 ,  B01D35/30 ,  B01D2201/291 ,  B01D2201/302 ,  B01D2201/4046 ,  B01D2201/4084 ,  B01D2313/02 ,  B01D2313/44

Abstract: A removable device that ensures that the port of a filter cartridge is liquid tightly sealed to the port of the head of a housing even when there is insufficient room beneath the bowl to allow one to physically secure the cartridge port to the head port before securing the head and bowl together. The invention uses one or more removably attached alignment devices to center the cartridge in the bowl and maintain it at a height sufficient to ensure that the two ports are aligned and liquid tightly sealed to each other when the bowl and head are mated together.

Abstract translation: 一种可移除的装置，其确保过滤器滤芯的端口液密地密封到壳体的头部的端口，即使在碗下方没有足够的空间以允许在固定之前物理地将盒式端口固定到头端口 头和碗在一起。 本发明使用一个或多个可移除地附接的对准装置将筒定位在碗中，并将其保持在足够高的高度，以确保当碗和头配合在一起时两个端口对准并且彼此液密地密封。

公开(公告)号：US20140299531A1

公开(公告)日：2014-10-09

申请号：US14311399

申请日：2014-06-23

Applicant: EMD Millipore Corporation

Inventor： Sebastien Cirou ,  Jean-Louis Weissenbach ,  Rene Reinbigler ,  Jean-Luc Beulay ,  Frans Mels ,  Cecile Delbos

IPC: B01D25/127

CPC classification number: B23P19/04 ,  B01D25/127 ,  B01D25/14 ,  B01D25/164 ,  B01D25/19 ,  B01D61/18 ,  B01D61/20 ,  B01D63/082 ,  B01D2313/02 ,  B01D2313/06 ,  B01D2313/105 ,  B01D2313/125 ,  Y10T29/49826

Abstract: The invention concerns a filtration device comprising a manifold providing fluid connection and mechanical connection comprising a clamping plate movably mounted relative to the manifold and adapted to compress at least one cassette against the manifold, means for driving and guiding the clamping plate comprising a rod extending between the manifold and the plate, an actuator provided with a body and a member moveable relative to the body, which member is adapted to move through a predetermined travel between an extended position and a retracted position, the body being carried by the manifold, and the member carrying the rod and driving the plate via the rod to a clamped position in which the member is in an intermediate retracted position in which it has moved through a shorter travel than the predetermined travel relative to its extended position.

Abstract translation: 本发明涉及一种过滤装置，其包括提供流体连接的歧管和机械连接，其包括相对于歧管可移动地安装的夹板，并且适于将至少一个盒压靠在歧管上，用于驱动和引导夹板的装置， 所述歧管和所述板，致动器，其设置有主体和可相对于所述主体移动的构件，所述构件适于在延伸位置和缩回位置之间移动通过预定行程，所述主体由所述歧管承载，并且所述主体 承载杆并且通过杆将板驱动到夹紧位置，在该夹紧位置处，构件处于中间缩回位置，在该夹紧位置中，其已经相对于其延伸位置移动比预定行程更短的行程。

公开(公告)号：US20140299530A1

公开(公告)日：2014-10-09

申请号：US14311395

申请日：2014-06-23

Applicant: EMD Millipore Corporation

Inventor： Sebastien Cirou ,  Jean-Louis Weissenbach ,  Rene Reinbigler ,  Jean-Luc Beulay ,  Frans Mels ,  Cecile Delbos

IPC: B01D25/127

CPC classification number: B23P19/04 ,  B01D25/127 ,  B01D25/14 ,  B01D25/164 ,  B01D25/19 ,  B01D61/18 ,  B01D61/20 ,  B01D63/082 ,  B01D2313/02 ,  B01D2313/06 ,  B01D2313/105 ,  B01D2313/125 ,  Y10T29/49826

Abstract: The invention concerns a filtration device comprising a providing fluid connection and mechanical connection comprising a clamping plate movably mounted relative to the manifold and adapted to compress at least one cassette against the manifold, means for driving and guiding the clamping plate comprising a rod extending between the manifold and the plate, an actuator provided with a body and a member moveable relative to the body, which member is adapted to move through a predetermined travel between an extended position and a retracted position, the body being carried by the manifold, and the member carrying the rod and driving the plate via the rod to a clamped position in which the member is in an intermediate retracted position in which it has moved through a shorter travel than the predetermined travel relative to its extended position.

Abstract translation: 本发明涉及一种过滤装置，包括提供流体连接和机械连接，其包括可相对于歧管可移动地安装的夹板，并且适于将至少一个盒体压靠在歧管上，用于驱动和引导夹板的装置， 歧管和板，致动器，其设置有主体和可相对于主体移动的构件，该构件适于在延伸位置和缩回位置之间移动通过预定行程，所述主体由歧管承载，并且构件 承载杆并经由杆驱动板到夹紧位置，在夹紧位置中，构件处于中间缩回位置，在夹紧位置中，其已经相对于其延伸位置移动经过比预定行程更短的行程。

公开(公告)号：US20140252084A1

公开(公告)日：2014-09-11

申请号：US14282831

申请日：2014-05-20

Applicant: EMD Millipore Corporation

Inventor： Aaron Burke ,  David DeCoste

IPC: B65D25/20 ,  G06K7/10

CPC classification number: B65D25/205 ,  B31B50/81 ,  B31D1/028 ,  B65D33/004 ,  B65D75/566 ,  B65D75/5877 ,  B65D2203/10 ,  G06K7/10237 ,  Y10T29/49016 ,  Y10T156/10

Abstract: The present invention provides a process for incorporating a wireless device into a plastic container as part of the steps of manufacturing the container. The plastic container can be a flexible plastic bag and are formed of one or more sheets, generally two or more sheets of plastic film or a rigid plastic container such as a tub or tote. The bags are formed by sealing together adjacent edge portions of each film layer. One embodiment of the present invention is to incorporate a wireless device between the edge portions of the film(s) before or during sealing so that the wireless device becomes permanently sealed into the film material but is isolated from both the bag interior and the outside environment. Another embodiment is to incorporate the wireless device onto or into a plastic component that is sealed to the container, such as a nipple or port, so that the wireless device becomes permanently sealed to the container but is isolated from both the container interior and the outside environment.

Abstract translation: 本发明提供了一种将无线装置结合到塑料容器中的方法，作为制造容器的步骤的一部分。 塑料容器可以是柔性塑料袋，并且由一个或多个片材形成，一般为两层或更多张塑料薄膜或诸如桶或手提箱的刚性塑料容器。 袋子通过将每个膜层的相邻边缘部分密封在一起而形成。 本发明的一个实施例是在密封之前或期间将无线设备结合在胶片的边缘部分之间，使得无线设备永久地密封到胶片材料中，但与袋内部和外部环境隔离 。 另一个实施例是将无线设备结合到密封到容器（例如乳头或端口）上的塑料部件上，使得无线设备永久地密封到容器，但是与容器内部和外部隔离 环境。

公开(公告)号：US08815067B2

公开(公告)日：2014-08-26

申请号：US13887657

申请日：2013-05-06

Applicant: EMD Millipore Corporation

Inventor： Andrej Grabowski

IPC: B01D61/54 ,  B01J49/00 ,  B01D61/52 ,  B01D61/48 ,  C02F1/469

CPC classification number: C02F1/4695 ,  B01D61/485 ,  B01D61/52 ,  B01D61/54 ,  B01J47/028 ,  B01J47/04 ,  B01J47/06 ,  B01J49/09 ,  B01J49/30 ,  C02F2209/03 ,  C02F2303/16

Abstract: Device for the removal of ions from a polar liquid, e.g. water, comprising at least one compartment which comprises at least one inlet for an entering polar liquid flow and at least one outlet for an outgoing deionized liquid flow, in which said compartment an electrochemically regenerable ion-exchange material fills a zone through which zone a liquid flow is able to pass, the device being characterized in that it comprises one sensor of at least one dimensional change of the ion-exchange material. The sensor can comprise a photo-sensor or a sensor of mechanical stress. Preferably an apparatus connected to the sensor is able to analyze this dimensional change and to control the electric current. Method of using said device, whereby the electrical current applied to the device is controlled according to the expansion of the resin.

Abstract translation: 用于从极性液体除去离子的装置，例如 水，包括至少一个隔室，其包括用于进入的极性液体流的至少一个入口和用于输出的去离子液体流的至少一个出口，其中所述隔室为电化学可再生的离子交换材料填充通过该区域的液体 流动能够通过，该装置的特征在于它包括离子交换材料的至少一维变化的一个传感器。 传感器可以包括光传感器或机械应力传感器。 优选地，连接到传感器的装置能够分析该尺寸变化并控制电流。 使用所述装置的方法，由此根据树脂的膨胀来控制施加到装置的电流。

公开(公告)号：US20140220246A1

公开(公告)日：2014-08-07

申请号：US14189174

申请日：2014-02-25

Applicant: EMD Millipore Corporation

Inventor： Gabriel Tkacik ,  Philip Goddard ,  Willem Kools ,  Nitin Satav

IPC: B01D69/12

CPC classification number: B01D69/12 ,  B01D61/145 ,  B01D67/0013 ,  B01D67/0016 ,  B01D67/0018 ,  B01D71/34 ,  B01D71/68 ,  B01D2323/12 ,  B01D2323/42 ,  B01D2325/022 ,  C07K1/34

Abstract: The present invention is an integral multilayered composite membrane having at least one ultrafiltration layer made by cocasting or sequentially casting a plurality of polymer solutions onto a support to form a multilayered liquid sheet and immersing the sheet into a liquid coagulation bath to effect phase separation and form a multilayered composite membrane having at least one ultrafiltration layer.

Abstract translation: 本发明是一种具有至少一个超滤层的整体式多层复合膜，该超滤层是通过将多种聚合物溶液共沉淀或依次浇注到载体上形成多层液体薄片并将该薄片浸入液体凝固浴中以进行相分离和形成 具有至少一个超滤层的多层复合膜。

公开(公告)号：US20140202967A1

公开(公告)日：2014-07-24

申请号：US14119496

申请日：2012-06-08

Applicant: EMD Millipore Corporation

Inventor： Stephane Olivier ,  Didier Metz

IPC: B01D27/04

Abstract: The invention relates to the filtering of liquid samples, preferably in a laboratory environment, for example for collecting micro organisms from the liquid sample for subsequent testing. The invention provides a method for filtering a liquid sample which comprises providing a blank of a deformable sheet material and a filtration medium, deforming the blank to form a funnel extending above and about the filtration medium, introducing the liquid sample to be filtered into the so formed funnel, and filtering the liquid sample from the funnel through the filtration medium, for example to a downstream receptacle. The method is accordingly based on the concept that the funnel is not or at least not completely preformed but provided in a form of a blank of a deformable material sheet which is deformed so as to form the funnel at the point and time of use during filtration.

Abstract translation: 本发明涉及液体样品的过滤，优选在实验室环境中，例如用于从液体样品中收集微生物用于随后的测试。 本发明提供了一种用于过滤液体样品的方法，该方法包括提供可变形片材料和过滤介质的坯件，使坯料变形以形成在过滤介质上方和周围延伸的漏斗，将待过滤的液体样品引入 并且将来自漏斗的液体样品通过过滤介质过滤，例如到下游容器。 因此，该方法基于以下概念：漏斗不是或至少不完全预成型，而是以可变形材料片的坯料的形式提供，该可变形材料片在过滤期间在使用的时间点变形以形成漏斗 。

公开(公告)号：US20140173876A1

公开(公告)日：2014-06-26

申请号：US14191499

申请日：2014-02-27

Applicant: EMD Millipore Corporation

Inventor： James Hobson ,  James Austin ,  Boris Pesakovich ,  Elias G. Noukas ,  Thomas Janko ,  Shaun McMahon

IPC: B65F1/06

CPC classification number: A61J1/10 ,  B65B69/0091 ,  B65D88/20 ,  B65D90/046 ,  B65D2203/10 ,  B65D2303/00 ,  B65F1/06 ,  Y10T29/49826

Abstract: The present invention is an alignment device for a bag containing one or more ports. The alignment device is attached to either the one or more ports or to the bag adjacent the one or more ports. The plate has an indicator or a unique outer edge shape that is designed to fit into a corresponding unique opening in a holder to ensure proper alignment of the bag and its port(s) in the holder. The plate is has a Series of holes equal to and in alignment with the one or more ports of the bag and the port(s) extend through the holes of the plate,

Abstract translation: 本发明是一种用于包含一个或多个端口的袋的对准装置。 对准装置附接到一个或多个端口或邻近一个或多个端口的袋。 该板具有指示器或独特的外边缘形状，其被设计成装配在保持器中相应的独特开口中，以确保袋和其端口在保持器中的适当对准。 板具有与袋的一个或多个端口相等并且对准的一系列孔，并且该端口延伸穿过板的孔，

公开(公告)号：US20140090735A1

公开(公告)日：2014-04-03

申请号：US14053688

申请日：2013-10-15

Applicant: EMD Millipore Corporation

Inventor： Paul Ju-Sung Hung ,  Philip Janmin Lee

IPC: F16K27/02

CPC classification number: C12M23/12 ,  B01L3/5025 ,  B01L3/502707 ,  B01L3/502715 ,  B01L3/50273 ,  B01L3/502738 ,  B01L3/502746 ,  B01L2200/12 ,  B01L2300/0681 ,  B01L2300/0816 ,  B01L2300/0819 ,  B01L2300/10 ,  B01L2300/123 ,  B01L2300/14 ,  B01L2400/0481 ,  B01L2400/0487 ,  B01L2400/0655 ,  B29C65/002 ,  C12M23/16 ,  C12M29/10 ,  C12M29/14 ,  C12M41/00 ,  C12M41/48 ,  C12Q1/025 ,  F16K27/0236 ,  F16K99/0001 ,  F16K99/0015 ,  F16K99/0059 ,  F16K2099/0074 ,  F16K2099/0078 ,  F16K2099/0084 ,  G01N33/5008 ,  G01N33/54366 ,  G01N2035/00158 ,  Y10T137/2202

Abstract: A valved microfluidics device, microfluidics cell-culture device and system incorporating the devices are disclosed. The valved microfluidics device includes a substrate, a microchannel through which liquid can be moved from one station to another within the device, and a pneumatic microvalve adapted to be switched between open and closed states to control the flow of fluid through a microchannel. The microvalve is formed of three flexible membranes, one of which is responsive to pneumatic pressure applied to the valve and the other two of which deform to produce a more sealable channel cross-section. The cell culture device provides valving to allow controlled loading of cells into the individual well of the device, and exchange of cell-culture components in the wells.

Abstract translation: 公开了一种带阀的微流体装置，微流体细胞培养装置和结合装置的系统。 带阀的微流体装置包括基底，微通道，通过该微通道液体可以在装置内从一个站移动到另一个站;以及气动微型阀，其适于在打开和关闭状态之间切换以控制通过微通道的流体流动。 微型阀由三个柔性膜形成，其中一个柔性膜响应于施加到阀上的气压，另外两个变形以产生更可密封的通道横截面。 细胞培养装置提供阀门以允许将细胞控制加载到装置的个体井中，以及在孔中交换细胞培养组分。

公开(公告)号：US08672144B2

公开(公告)日：2014-03-18

申请号：US13669494

申请日：2012-11-06

Applicant: EMD Millipore Corporation

Inventor： David P. Yavorsky

IPC: B01D39/20 ,  B01J20/14

CPC classification number: B01D39/2079 ,  B01D2239/0407 ,  B01D2239/08 ,  B01J20/10 ,  B01J20/103 ,  B01J20/14 ,  B01J20/165 ,  B01J20/18 ,  B01J20/20 ,  B01J20/28026 ,  B01J20/2803

Abstract: Adsorbent filter media particularly suited for removal of biological contaminants in process liquids. A porous fixed bed of adsorbent material is formed, using only a granular adsorbent and a water-insoluble thermoplastic binder. The resulting composite filter allows for a higher amount of adsorbent with smaller adsorbent particles than conventional depth filters. Elimination of cellulose fiber, as well as the elimination of the thermoset binder, results in reduced contamination of the process liquid.

Abstract translation: 吸附剂过滤介质特别适用于去除工艺液体中的生物污染物。 仅使用粒状吸附剂和水不溶性热塑性粘合剂形成吸附剂材料的多孔固定床。 所得到的复合过滤器允许比常规深度过滤器更大量的具有较小吸附剂颗粒的吸附剂。 消除纤维素纤维以及消除热固性粘合剂导致工艺液体的污染减少。