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公开(公告)号：US20160114319A1
公开(公告)日：2016-04-28
申请号：US14787230
申请日：2013-04-30
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor： Nicholas M. McGuinness , Manish Giri , Melinda M. Valencia , Chantelle Domingue , Andrew L. Van Brocklin , Dustin W. Blair
IPC: B01L3/00
CPC classification number: B01L3/50273 , B01L3/502715 , B01L3/502753 , B01L2200/10 , B01L2300/024 , B01L2300/0636 , B01L2300/0645 , B01L2300/0681 , B01L2400/0487 , G01N15/1031 , G01N2015/1006
Abstract: A microfluidic device can include: a channel; a fluid inlet to pass fluid into the channel from a reservoir; a sensor disposed in the channel; and a pump actuator disposed in the channel apart from the sensor to induce fluid flow into the channel.
Abstract translation: 微流体装置可以包括：通道; 流体入口将流体从储存器传送到通道中; 设置在通道中的传感器; 以及泵致动器，其布置在与传感器分开的通道中以引导流体流入通道。
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公开(公告)号：US11698332B2
公开(公告)日：2023-07-11
申请号：US15748393
申请日：2015-11-24
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor： Robert Moline , Manish Giri , Chantelle Domingue
IPC: G01N15/06 , B01L3/00 , C12Q1/25 , G01N33/487 , G01N33/543 , G01N1/38 , G01N33/50 , G01N15/00
CPC classification number: G01N15/0656 , B01L3/502715 , C12Q1/25 , G01N1/38 , G01N33/48707 , G01N33/50 , G01N33/54366 , B01L2200/027 , B01L2200/16 , B01L2300/0636 , B01L2300/0825 , B01L2300/0867 , B01L2300/1827 , B01L2400/0406 , B01L2400/0442 , B01L2400/0487 , G01N2015/0065
Abstract: Examples herein provide a device. The device includes a sample delivery component, which includes: a reagent chamber to contain at least one reagent; a sample chamber to contain a fluid sample; and a delivery channel extending from the reagent chamber and in fluid communication with the sample chamber and an output port, wherein the delivery channel is conducive mixing the at least one reagent and the fluid sample to form a mixture before the mixture reaches the output port and be discharged therefrom. The device includes a testing cassette detachable from the delivery component, which includes: an input port in fluid communication with a microfluidic reservoir, the input port to receive the discharged fluid sample from the output port; and a micro-fabricated integrated sensor in a microfluidic channel extending from the microfluidic reservoir.
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公开(公告)号：US11007529B2
公开(公告)日：2021-05-18
申请号：US16099658
申请日：2016-07-26
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor： Jeffrey A Nielsen , Manish Giri , Chantelle Domingue , Kenneth Ward , Christie Dudenhoefer , Matthew David Smith , Joshua M. Yu , Hilary Ely
Abstract: According to an example, a microfluidic apparatus may include a fluid slot, a foyer in fluid communication with the fluid slot via a channel having a relatively smaller width than the foyer, a sensor to detect a presence of a particle of interest in a fluid passing through the channel, a nozzle in fluid communication with the foyer, and an actuator positioned in line with the nozzle. The microfluidic apparatus may also include a controller to receive information from the sensor, determine, from the received information, whether a particle of interest has passed through the channel, and control the actuator to expel fluid in the foyer through the nozzle based upon the determination.
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公开(公告)号：US10725019B2
公开(公告)日：2020-07-28
申请号：US15522831
申请日：2015-01-30
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Melinda M Valencia , Chantelle E Domingue , Jeremy Sells , Manish Giri , Sadiq Bengali
Abstract: Example implementations relate to coagulation sensing. For example, a microfluidic chip for coagulation sensing may include a microfluidic channel, an outlet at an end of the microfluidic channel having an air interface, and an impedance sensor located within the microfluidic channel and within a particular proximity to the air interface, the impedance sensor to determine a stage of a coagulation cascade of a blood sample flowing through the microfluidic channel to the impedance sensor.
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公开(公告)号：US20190127219A1
公开(公告)日：2019-05-02
申请号：US16094411
申请日：2016-07-22
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor： Sadiq Bengali , Manish Giri
Abstract: Example sensor apparatus for microfluidic devices and related methods are disclosed. In examples disclosed herein, a method of fabricating a sensor apparatus for a microfluidic device includes etching a portion of an intermediate layer to form a sensor chamber in a substrate assembly, where the substrate assembly has a base layer and the intermediate layer, and where the base layer comprises a first material and the intermediate layer comprises a second material different than the first material. The method includes forming a first electrode and a second electrode in the sensor chamber. The method also includes forming a fluidic transport channel in fluid communication with the sensor chamber, where the fluidic transport channel comprises a third material different than the first material and the second material.
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Patent Agency Ranking
公开(公告)号：US10272428B2
公开(公告)日：2019-04-30
申请号：US14787230
申请日：2013-04-30
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Nicholas M. McGuinness , Manish Giri , Melinda M. Valencia , Chantelle Domingue , Andrew L. Van Brocklin , Dustin W. Blair
Abstract: A microfluidic device can include: a channel; a fluid inlet to pass fluid into the channel from a reservoir; a sensor disposed in the channel; and a pump actuator disposed in the channel apart from the sensor to induce fluid flow into the channel.
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公开(公告)号：US20190039063A1
公开(公告)日：2019-02-07
申请号：US15764975
申请日：2016-01-22
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor： Chantelle E. Domingue , Manish Giri
IPC: B01L3/00
Abstract: An apparatus includes a chamber, a nozzle connected to the chamber, a fluid driver proximate the driver to expel fluid from the chamber through the nozzle, a microfluidic passage, an inlet connecting the microfluidic passage and the chamber, a sensor proximate the inlet to sense fluid within a fluid sensing zone within the inlet, and a particle aggregation limiter to control aggregation of particles within the sensing zone.
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公开(公告)号：US20180043687A1
公开(公告)日：2018-02-15
申请号：US15546936
申请日：2015-04-30
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Alexander Govyadinov , Charles M. Santori , Anita Rogacs , Diane R. Hammerstad , Manish Giri
CPC classification number: B41J2/125 , B01L3/502707 , B01L3/502715 , B01L2300/0627 , B01L2400/0442 , B41J2/175 , B41J2/195 , G01N15/14 , G01N21/27 , G01N21/64 , G01N21/6454 , G01N21/85 , G01N2015/1486 , G01N2015/149 , G01N2015/1493 , G01N2021/8557 , G01V8/12
Abstract: Provided in one example is an apparatus, including a substrate supporting a microfluidic channel, a bubble jet inertial pump supported by the substrate adjacent the microfluidic channel to pump fluid through the microfluidic channel and an optical sensor on a first side of the microfluidic channel. A light emitter on a second side of the microfluidic channel is to pass light across the microfluidic channel to the optical sensor.
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公开(公告)号：US20180011042A1
公开(公告)日：2018-01-11
申请号：US15545406
申请日：2015-01-30
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Jeremy Sells , Chantelle E. Domingue , Manish Giri , Melinda M. Valencia
CPC classification number: G01N27/06 , B01L3/502715 , B01L2200/0652 , B01L2300/023 , B01L2300/0645 , G01N15/1031 , G01N15/1056 , G01N2015/0065 , G01N2015/1006
Abstract: A method of microfluidic detection can include detecting, using an impedance sensor, an impedance of a fluid to indicate whether a threshold amount of fluid has been received in a reservoir of a microfluidic chip. The method can include initiating a test performed by the microfluidic chip on the received fluid when the threshold amount of fluid has been received.
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公开(公告)号：US20180003614A1
公开(公告)日：2018-01-04
申请号：US15537752
申请日：2015-06-29
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Shameed Sait M. A. , Saleem Jaffer Majeeth , Manish Giri
CPC classification number: G01N15/1484 , B01L3/50273 , B01L7/00 , B01L7/52 , B01L2200/147 , B01L2300/023 , B01L2300/027 , B01L2300/1827 , B01L2400/0442 , G01N15/0266 , G01N15/1404 , G01N15/1429 , G01N15/1431 , G01N15/1459 , G01N35/00871 , G01N2015/0065 , G01N2015/1006 , G01N2015/1486 , G01N2015/1493 , G01N2035/00881 , G06F9/544 , G16H10/40 , G16H40/67 , H04L47/805 , H04L49/90
Abstract: A data receiver thread is continuously executed to receive in which signals indicating a fluid parameter. A predetermined time quantity of the signals is repeatedly buffered. Upon completion of the buffering of each predetermined time quantity of the signals, a data processing thread is initiated that executes on the just completed buffered predetermined time quantity of signals. Upon completion of each data processing thread, data from the just completed data processing thread is passed to a data plotting thread. Results of the data plotting thread are displayed on a portable electronic device while the data receiver thread is being executed.
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