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    POLYSACCHARIDE DERIVATIVE AND HYDROGEL THEREOF
    31.
    发明申请
    POLYSACCHARIDE DERIVATIVE AND HYDROGEL THEREOF 失效
    多糖衍生物和水合物

    公开(公告)号：US20120035128A1

    公开(公告)日：2012-02-09

    申请号：US13263929

    申请日：2010-04-19

    申请人： Hiroaki Kaneko ,  Masaya Ito

    发明人： Hiroaki Kaneko ,  Masaya Ito

    IPC分类号： A61K31/726 ,  C08B37/08 ,  A61K31/728 ,  A61K6/00 ,  A61K47/36 ,  C12N1/00 ,  A61L24/08 ,  C08B37/00 ,  A61P41/00

    CPC分类号： A61L27/52 ,  A61K9/0024 ,  A61K47/36 ,  A61L27/20 ,  A61L31/042 ,  A61L31/145 ,  C08B37/0072 ,  C08J3/075 ,  C08J2305/08 ,  C08L5/08

    摘要： Disclosed are a polysaccharide derivative obtained by substituting some of the carboxyl groups of a carboxy polysaccharide with —NH—X—CO—Y—Z; and a hydrogel thereof. Here, X is a C1-10 hydrocarbon group, Y is a polyalkylene oxide having oxygen atoms at both ends, and Z is a C1-24 hydrocarbon group or —CO—R2, with R2 being a C1-23 hydrocarbon group. The hydrogel has excellent viscoelasticity and can be injected into a predetermined location with an injection device such as a syringe, and thus can be advantageously used as a medical gel or an adhesion barrier.

    摘要翻译： 公开了通过用-NH-X-CO-Y-Z取代羧基多糖的一些羧基得到的多糖衍生物; 及其水凝胶。 这里，X是C 1-10烃基，Y是在两端具有氧原子的聚环氧烷烃，Z是C1-24烃基或-CO-R2，R2是C1-23烃基。 水凝胶具有优异的粘弹性，并且可以通过诸如注射器的注射装置注射到预定位置，因此可以有利地用作医用凝胶或粘合屏障。

    HYDROGEL OF POLYSACCHARIDE DERIVATIVE
    32.
    发明申请
    HYDROGEL OF POLYSACCHARIDE DERIVATIVE 审中-公开
    多糖衍生物的氢化物

    公开(公告)号：US20110301121A1

    公开(公告)日：2011-12-08

    申请号：US13202234

    申请日：2009-09-18

    申请人： Nobuyuki Endo ,  Masaya Ito ,  Hiroaki Kaneko ,  Hitoshi Hirata ,  Michiro Yamamoto

    发明人： Nobuyuki Endo ,  Masaya Ito ,  Hiroaki Kaneko ,  Hitoshi Hirata ,  Michiro Yamamoto

    IPC分类号： A61K31/717 ,  A61P25/00 ,  A61P41/00

    CPC分类号： A61L31/042 ,  A61K31/715 ,  A61K31/717 ,  A61L31/145 ,  A61L2430/32 ,  C08B15/05

    摘要： A nerve dysfunction repairing material including a hydrogel of a polysaccharide derivative that has, in a 0.5 wt % aqueous solution, a complex modulus of 1 to 1000 N/m2 and a loss factor of 0.01 to 2.0 as measured at an angular velocity of 10 rad/sec using a dynamic viscoelasticity measuring apparatus. The nerve dysfunction repairing material can be a hydrogel injectable through a syringe, has excellent retention in the body, and has a restorative effect on the function of damaged or degenerated nerves.

    摘要翻译： 一种神经功能障碍修复材料，其包括多糖衍生物的水凝胶，所述多糖衍生物在0.5重量％水溶液中的复数模量为1〜1000N / m 2，损失因子为0.01〜2.0，以角速度为10rad /秒，使用动态粘弹性测量装置。 神经功能障碍修复材料可以是通过注射器注射的水凝胶，在身体中具有优异的保留性，并且对损伤或退化的神经的功能具有恢复性作用。

    CELLULOSE DERIVATIVE AND HYDROGEL THEREOF
    33.
    发明申请
    CELLULOSE DERIVATIVE AND HYDROGEL THEREOF 失效
    纤维素衍生物和水合物

    公开(公告)号：US20110129505A1

    公开(公告)日：2011-06-02

    申请号：US12808613

    申请日：2008-12-17

    申请人： Hiroaki Kaneko ,  Nobuyuki Endo ,  Masaya Ito

    发明人： Hiroaki Kaneko ,  Nobuyuki Endo ,  Masaya Ito

    IPC分类号： C08B11/193 ,  C08B1/00 ,  C08B11/15 ,  C08B11/12 ,  A61K9/00

    CPC分类号： A61L27/20 ,  A61L27/52 ,  A61L31/042 ,  A61L31/145 ,  C08B11/12 ,  C08L1/26

    摘要： The invention is a cellulose derivative wherein some of the carboxyl groups of the cellulose derivative carboxymethylcellulose are replaced with —CO—NH—X—CO—Y—Z, and a hydrogel of the same. In the formula, X is a C1-10 divalent hydrocarbon group, Y is a divalent group derived from polyalkylene oxide having oxygen atoms at both ends, and Z is a C1-24 hydrocarbon group or —CO—R4, where R4 is a C1-23 hydrocarbon group.The hydrogel has excellent viscoelasticity and can be injected into prescribed sites with injecting devices such as syringes, and it can thus be utilized as a medical gel or adhesion barrier.

    摘要翻译： 本发明是纤维素衍生物羧甲基纤维素的一些羧基被-CO-NH-X-CO-Y-Z代替的纤维素衍生物及其水凝胶。 在该式中，X是C 1-10二价烃基，Y是衍生自在两端具有氧原子的聚环氧烷烃，Z是C1-24烃基或-CO-R4的二价基团，其中R4是C1 -23烃基。 水凝胶具有优异的粘弹性，并且可以用诸如注射器的注射装置注射到规定的位置，因此可以用作医用凝胶或粘附屏障。

    CELLULOSE DERIVATIVE
    34.
    发明申请
    CELLULOSE DERIVATIVE 有权
    纤维素衍生物

    公开(公告)号：US20100279982A1

    公开(公告)日：2010-11-04

    申请号：US11997830

    申请日：2006-08-03

    申请人： Hiroaki Kaneko ,  Eiichi Kitazono ,  Masaya Ito ,  Yoshihiko Sumi

    发明人： Hiroaki Kaneko ,  Eiichi Kitazono ,  Masaya Ito ,  Yoshihiko Sumi

    IPC分类号： A61K31/717 ,  C08B15/05 ,  A61P41/00

    CPC分类号： C08B11/20 ,  A61L31/042 ,  C08B15/05 ,  C08L1/00

    摘要： A cellulose derivative which has a suitable elastic modulus and viscosity when it is dissolved in water and is useful as an adhesion barrier.The cellulose derivative has a molecular weight of 5×103 to 5×106 and is composed of a repeating unit represented by the following formula (1): wherein R1, R2 and R3 are each independently selected from the group consisting of the following formulas (a), (b), (c) and (d) in predetermined amount: (X in the formula (c) is an alkali metal, and R4 and R5 in the formula (d) are each independently an alkyl group or alkenyl group having 10 to 28 carbon atoms).

    摘要翻译： 当纤维素衍生物溶于水中时具有合适的弹性模量和粘度并且可用作粘合屏障。 纤维素衍生物的分子量为5×10 3〜5×10 6，由下述式（1）表示的重复单元构成：其中，R 1，R 2，R 3各自独立地选自下述式 a），（b），（c）和（d））：（式（c）中的X是碱金属，式（d）中的R 4和R 5各自独立地为烷基或烯基 具有10至28个碳原子）。

    Ceramic heater and glow plug having the same
    35.
    发明授权
    Ceramic heater and glow plug having the same 有权
    陶瓷加热器和电热塞具有相同的功能

    公开(公告)号：US07282670B2

    公开(公告)日：2007-10-16

    申请号：US10510346

    申请日：2003-04-28

    申请人： Katsura Matsubara ,  Hiroki Watanabe ,  Masaya Ito

    发明人： Katsura Matsubara ,  Hiroki Watanabe ,  Masaya Ito

    IPC分类号： F23Q7/22 ,  F23Q7/00

    CPC分类号： H05B3/283 ,  F23Q7/001 ,  H05B3/141 ,  H05B2203/027

    摘要： The present invention relates to a ceramic heater which is capable of preventing an electric conduction defect of a heat-generating resistor from being caused by a supplied current, thus being excellent in voltage endurance, and a glow plug containing the ceramic heater. The ceramic heater 2 contained in the glow plug 1 has an insulative ceramic base material 21 and the heat-generating resistor 22 embedded in the insulative ceramic base material. The heat-generating resistor 22 has, as main components, an electrically conductive compound, silicon nitride and a grain boundary amorphous glass phase. The amount of the rare earth element contained in the heat-generating resistor is less than 2% by volume in terms of its oxide and, further, a molar ratio R=(A/A+B) of the mol number A of the amount of the rare earth element in terms of its oxide to a total of the mol number A and a mol number B, which is the amount of excess oxygen in terms of silicon dioxide, is 0.3 or less. By achieving such a constitution, the heat-generating resistor is capable of preventing electric conduction defects and of being excellent in voltage endurance.

    摘要翻译： 陶瓷加热器技术领域本发明涉及一种陶瓷加热器，其能够防止发热电阻器的导电缺陷由供电电流引起，因此耐电压优异，以及包含陶瓷加热器的电热塞。 包含在电热塞1中的陶瓷加热器2具有嵌入在绝缘陶瓷基材中的绝缘陶瓷基材21和发热电阻22。 作为主要成分的发热电阻体22具有导电性化合物，氮化硅和晶界非晶质玻璃相。 发热电阻体中含有的稀土元素的含量以氧化物计小于2体积％，另外摩尔数A的摩尔比R =（A / A + B） 的稀土元素的氧化物总计为摩尔数A，摩尔数B为二氧化硅换算的过量氧的量为0.3以下。 通过实现这样的结构，发热电阻器能够防止导电缺陷和耐压性优异。

    Method of forming tappet of the kind having ceramic seat plate
    36.
    发明授权
    Method of forming tappet of the kind having ceramic seat plate 失效
    形成具有陶瓷座板的挺杆的方法

    公开(公告)号：US5253418A

    公开(公告)日：1993-10-19

    申请号：US830340

    申请日：1992-01-31

    申请人： Masato Taniguchi ,  Masaya Ito

    发明人： Masato Taniguchi ,  Masaya Ito

    IPC分类号： B23P15/00 ,  F01L1/14 ,  F02B3/06

    CPC分类号： B23P15/00 ,  F01L1/14 ,  F01L2101/00 ,  F01L2103/00 ,  F02B3/06 ,  Y10T29/49295 ,  Y10T29/49304

    摘要： A tappet for an internal combustion engine consists of a tappet main body and a ceramic seat plate brazed to the tappet main body. The tappet main body is made up of a first part made of low carbon steel and a second part made of metal. In manufacture, the first and second parts are first welded together to constitute the tappet main body, and then the ceramic seat is brazed to the tappet main body. The low carbon steel forming the first part of the tappet main body has such a property that when carburized it can be hardened by making use of the heat for the brazing, and the metal forming the second part of the tappet main body has such a property that it can be hardened by making use of the heat for the brazing.

    摘要翻译： 用于内燃机的挺杆由挺杆主体和钎焊到挺杆主体的陶瓷座板组成。 挺杆主体由低碳钢制成的第一部分和金属制成的第二部分构成。 在制造时，第一和第二部分首先被焊接在一起以构成挺杆主体，然后陶瓷座被钎焊到挺杆主体上。 形成挺杆主体的第一部分的低碳钢具有这样的特性：当渗碳时，可以通过利用用于钎焊的热来硬化，并且形成挺杆主体的第二部分的金属具有这样的性质 它可以通过利用热量进行硬化来进行钎焊。

    Ceramic and metal joining structure
    38.
    发明授权
    Ceramic and metal joining structure 失效
    陶瓷和金属接合结构

    公开(公告)号：US4984927A

    公开(公告)日：1991-01-15

    申请号：US312383

    申请日：1989-02-17

    申请人： Takio Kojima ,  Masaya Ito

    发明人： Takio Kojima ,  Masaya Ito

    IPC分类号： B23K20/00 ,  C04B37/02 ,  F01D5/04 ,  F16D1/068

    CPC分类号： C04B37/026 ,  F16D1/068 ,  C04B2237/123 ,  C04B2237/125 ,  C04B2237/126 ,  C04B2237/368 ,  C04B2237/403 ,  C04B2237/406 ,  C04B2237/72 ,  C04B2237/76 ,  C04B2237/88 ,  Y10T403/217 ,  Y10T403/479 ,  Y10T403/48 ,  Y10T403/74

    摘要： Ceramic and metal shafts are joined at their ends by brazing, with a buffer member being interposed therebetween. The joined ends of the ceramic and metal shafts and the buffer member are received within a metal sleeve and joined by brazing to part of the inner circumferential wall of the metal sleeve in such a manner than an axial end of the joint where the inner circumferential wall is securely joined to the ceramic and metal shafts is positioned between opposite axial ends of the metal sleeve and at the same time between opposite axial ends of the ceramic shaft. The outer circumferential wall of the metal sleeve is formed with an annular groove in the place corresponding to the above mentioned axial end of the joint with respect to the axial direction of the metal sleeve.

    摘要翻译： 陶瓷和金属轴在其端部通过钎焊接合，缓冲构件插入其间。 陶瓷和金属轴和缓冲构件的接合端容纳在金属套筒内，并且以与接头的轴向端部不同的方式通过钎焊连接到金属套筒的内周壁的一部分，其中内周壁 被牢固地接合到陶瓷上，并且金属轴定位在金属套筒的相对的轴向端部之间并且同时位于陶瓷轴的相对的轴向端部之间。 金属套筒的外周壁相对于金属套筒的轴向在与接头的上述轴向端相对应的位置上形成有环形槽。

    Wire-cut electric discharge machine
    39.
    发明授权
    Wire-cut electric discharge machine 失效
    线切割放电机

    公开(公告)号：US4689457A

    公开(公告)日：1987-08-25

    申请号：US878837

    申请日：1986-06-12

    申请人： Shunzo Izumiya ,  Yuji Okuyama ,  Masaya Ito

    发明人： Shunzo Izumiya ,  Yuji Okuyama ,  Masaya Ito

    IPC分类号： B23H7/02 ,  B23H3/00 ,  B23H7/10 ,  B23H1/02 ,  B23H7/04

    CPC分类号： B23H7/10 ,  B23H3/00

    摘要： A wire-cut electric discharge machine, which displays a workable time (T) of a currently used wire electrode (2). A wire length when the wire is mounted on a bobbin (B1) and a wire feed speed are input through a manual input unit (7) and are stored in memory (6). During working (i.e., machining), a CPU (5) calculates a new, remaining wire length (L) from the wire length when the wire is mounted on the bobbin or a remaining wire length (L) and a wire feed speed (V) for predetermined time periods (step S1). A workable time (T) is calculated from the new, remaining wire length (L) and the wire feed speed (V) by the CPU (5), and is displayed by a display unit (8) (steps S2 and S3).

    摘要翻译： PCT No.PCT / JP85 / 00564 Sec。 371日期：1986年6月12日 102（e）日期1986年6月12日PCT提交1985年10月11日PCT公布。 第WO86 / 02299号公报 日期：1986年04月24日。一种线切割放电机，其显示当前使用的线电极（2）的可工作时间（T）。 通过手动输入单元（7）输入电线安装在线轴（B1）上的导线长度和送丝速度，并存储在存储器（6）中。 在加工（即加工）期间，CPU（5）在将线安装在线轴上时的线长度或剩余线长度（L）和送丝速度（V）中计算新的剩余线长度（L） ）预定时间段（步骤S1）。 根据CPU（5）的新的剩余电线长度（L）和送丝速度（V）计算可行时间（T），并由显示单元（8）显示（步骤S2和S3）。