公开(公告)号：US20050079619A1

公开(公告)日：2005-04-14

申请号：US10882104

申请日：2004-06-29

申请人： Terry Roemer ,  Bo Jiang ,  Charles Boone ,  Howard Bussey

发明人： Terry Roemer ,  Bo Jiang ,  Charles Boone ,  Howard Bussey

IPC分类号： A61K39/00 ,  C07K14/37 ,  C07K14/40 ,  C12N15/10 ,  C12N15/65 ,  C12N15/80 ,  C12N15/90 ,  C12N1/18 ,  C12N15/74

CPC分类号： C12R1/645 ,  A61K39/00 ,  C07K14/37 ,  C07K14/40 ,  C07K2319/00 ,  C12N15/1034 ,  C12N15/65 ,  C12N15/80 ,  C12N15/90 ,  C12R1/725

摘要： The present invention provides methods and compositions that enable the experimental determination as to whether any gene in the genome of a diploid pathogenic organism is essential, and whether it is required for virulence or pathogenicity. The methods involve the construction of genetic mutants in which one allele of a specific gene is inactivated while the other allele of the gene is placed under conditional expression. The identification of essential genes and those genes critical to the development of virulent infections, provides a basis for the development of screens for new drugs against such pathogenic organisms. The present invention further provides Candida albicans genes that are demonstrated to be essential and are potential targets for drug screening. The nucleotide sequence of the target genes can be used for various drug discovery purposes, such as expression of the recombinant protein, hybridization assay and construction of nucleic acid arrays. The uses of proteins encoded by the essential genes, and genetically engineered cells comprising modified alleles of essential genes in various screening methods are also encompassed by the invention.

摘要翻译： 本发明提供了能够对二倍体致病生物体的基因组中的任何基因是否必需的实验测定以及是否需要毒力或致病性的方法和组合物。 该方法包括构建遗传突变体，其中特定基因的一个等位基因被灭活而基因的其他等位基因置于条件表达下。 识别必需基因和对致病性感染发展至关重要的那些基因，为开发针对这种致病生物的新药筛选提供了基础。 本发明进一步提供了被证实是必需的白念珠菌基因，并且是药物筛选的潜在靶标。 靶基因的核苷酸序列可以用于各种药物发现目的，例如重组蛋白的表达，杂交测定和核酸阵列的构建。 在各种筛选方法中，由必需基因编码的蛋白质的使用以及包含必需基因的修饰的等位基因的遗传工程改造的细胞也包括在本发明中。

公开(公告)号：US20050002221A1

公开(公告)日：2005-01-06

申请号：US10902450

申请日：2004-07-29

申请人： Tie Wu ,  Chien-Chang Huang ,  Yu-Wei Ting ,  Bo Jiang

发明人： Tie Wu ,  Chien-Chang Huang ,  Yu-Wei Ting ,  Bo Jiang

IPC分类号： G11C8/14 ,  H01L21/8242 ,  H01L23/544 ,  H01L27/02 ,  G11C11/24

CPC分类号： H01L27/10861 ,  G11C8/14 ,  H01L22/34 ,  H01L27/0207 ,  H01L27/1087 ,  H01L27/10891

摘要： A test key for validating the position of a word line structure overlaying a deep trench capacitor of a DRAM. The test key is deposited in the scribe line region of a wafer. The deep trench capacitor is deposited in the scribe line region and has a buried plate. A rectangular word line is deposited in the scribe line and covers a portion of the deep trench capacitor, and two passing word lines are deposited above the deep trench. A first doping region and a second doping region are deposited between the rectangular word line and the first passing word line and between the rectangular word line and the second passing word line respectively. A first plug, a second plug and a third plugs are coupled to the first doping region, the second doping region and the buried plate respectively.

摘要翻译： 用于验证覆盖DRAM的深沟槽电容器的字线结构的位置的测试键。 测试键被沉积在晶片的划线区域中。 深沟槽电容器沉积在划线区域并具有掩埋板。 在划线中沉积矩形字线并覆盖深沟槽电容器的一部分，并且在深沟槽上方沉积两条经过的字线。 第一掺杂区域和第二掺杂区域分别沉积在矩形字线和第一通过字线之间以及矩形字线和第二通过字线之间。 第一插头，第二插头和第三插头分别耦合到第一掺杂区域，第二掺杂区域和掩埋板。

公开(公告)号：US06320784B1

公开(公告)日：2001-11-20

申请号：US09524916

申请日：2000-03-14

申请人： Ramachandran Muralidhar ,  Sucharita Madhukar ,  Bo Jiang ,  Bruce E. White ,  Srikanth B. Samavedam ,  David L. O'Meara ,  Michael Alan Sadd

发明人： Ramachandran Muralidhar ,  Sucharita Madhukar ,  Bo Jiang ,  Bruce E. White ,  Srikanth B. Samavedam ,  David L. O'Meara ,  Michael Alan Sadd

IPC分类号： G11C1100

CPC分类号： B82Y10/00 ,  G11C11/56 ,  G11C11/5671 ,  G11C16/0416 ,  G11C2216/08 ,  H01L29/7887 ,  H01L29/7888

摘要： A memory cell (101), its method of formation, and operation are disclosed. In accordance with one embodiment, the memory cell (101) comprises a first and second current carrying electrode (12) a control electrode (19), and doped discontinuous storage elements (17). In accordance with an alternative embodiment, memory cell programming is accomplished by removing or adding an average of approximately at least a first charge (30, 62, 64), which can be electron(s) or hole(s) from each of the doped discontinuous storage elements (17).

摘要翻译： 公开了一种存储单元（101），其形成方法和操作。 根据一个实施例，存储单元（101）包括第一和第二载流电极（12），控制电极（19）和掺杂的非连续存储元件（17）。 根据替代实施例，存储器单元编程通过去除或添加大约至少第一电荷（30,62,64）的平均值来实现，所述第一电荷可以是来自掺杂的每一个的电子或空穴 不连续存储元件（17）。

公开(公告)号：US6107136A

公开(公告)日：2000-08-22

申请号：US134974

申请日：1998-08-17

申请人： Bradley M. Melnick ,  Bruce E. White, Jr. ,  Douglas R. Roberts ,  Bo Jiang

发明人： Bradley M. Melnick ,  Bruce E. White, Jr. ,  Douglas R. Roberts ,  Bo Jiang

IPC分类号： H01L21/02 ,  H01L21/8242

CPC分类号： H01L28/91

摘要： A dielectric film (110) is formed overlying a semiconductor device substrate (10). A dielectric post (204) having an outer peripheral boundary having sidewalls is formed over the dielectric film (110). A first conductive film (402) is deposited at least along the sidewalls of the dielectric post (204) to form a lower electrode. A capacitor dielectric film (1801) is deposited on the first conductive film, and a upper electrode (1802) is formed on the capacitor dielectric film (1801).

摘要翻译： 覆盖在半导体器件基板（10）上的绝缘膜（110）形成。 在绝缘膜（110）上方形成具有侧壁外周边界的电介质柱（204）。 至少沿着电介质柱（204）的侧壁沉积第一导电膜（402）以形成下电极。 电容器电介质膜（1801）沉积在第一导电膜上，并且在电容器电介质膜（1801）上形成上电极（1802）。

公开(公告)号：US20220328995A1

公开(公告)日：2022-10-13

申请号：US17366011

申请日：2021-07-01

申请人： BO-JIANG TECHNOLOGY CO., LTD.

发明人： Chang-Hui Chiang

IPC分类号： H01R13/41 ,  H01R24/50

摘要： A coaxial connector is provided. The coaxial connector includes a shell, a first fixing member, a second fixing member, and a core body. The first fixing member and the second fixing member are disposed in a fixing thru-hole of the shell. One end of the first fixing member abuts against one end of the second fixing member. One portion of the core body is disposed in the first fixing member and the second fixing member. An inner diameter of a first inner engaging portion of the first fixing member changes with a length thereof, and an inner diameter of a second inner engaging portion of the second fixing member is uniform. An outer diameter of an engaging portion of the core body changes with a length thereof, and an outer diameter of an auxiliary engaging portion of the core body is uniform.

公开(公告)号：US10132463B2

公开(公告)日：2018-11-20

申请号：US12222825

申请日：2008-08-18

申请人： Chi Fai Cheung ,  Sandy To ,  Wing Bun Lee ,  Jin Bo Jiang ,  Bo Wang

发明人： Chi Fai Cheung ,  Sandy To ,  Wing Bun Lee ,  Jin Bo Jiang ,  Bo Wang

IPC分类号： F21V5/00 ,  F21V5/04 ,  F21V7/00 ,  G02B19/00 ,  F21S43/14 ,  F21S43/20 ,  F21S43/31 ,  F21Y115/10

摘要： The present invention relates to LED lamps suitable for forming automotive lighting systems, made of high power lambertian LEDs and a TIR collimator lens. In the present invention, a novel TIR collimator lens is developed to collect the light emitted from the LED source and through a pillow lens array; redistribution occurs to form a light pattern meeting ECE requirements.

公开(公告)号：US20160045104A1

公开(公告)日：2016-02-18

申请号：US14779558

申请日：2015-04-16

申请人： Bo JIANG ,  Jianhui ZHANG

发明人： Bo JIANG ,  Jianhui ZHANG

IPC分类号： A61B1/273 ,  A61B1/06 ,  A61B1/00 ,  A61B1/04

CPC分类号： A61B1/273 ,  A61B1/00006 ,  A61B1/00018 ,  A61B1/00032 ,  A61B1/00096 ,  A61B1/0011 ,  A61B1/00128 ,  A61B1/00137 ,  A61B1/00142 ,  A61B1/041 ,  A61B1/0684

摘要： The present invention discloses a flexible-wire traction-type capsule endoscope and a manufacture method thereof, which mainly includes a capsule endoscope housed in a pockety body and leads out a flexible wire for traction. The manufacture method of the flexible-wire traction-type capsule endoscope includes steps of mold integrating, film coating, adhering, shaping, assembling, sealing and wire fixing. According to the present invention, a finished product of the flexible-wire traction-type capsule endoscope is prepared by assembling a conventional capsule endoscope with a processed pockety body, and finally sealing and fixing. The manufacturing technique of the product is simple and easy, raw materials used are natural without pollution and are cheap, and the processing procedure is easy to be automatized, i.e., the productivity is easy to improve; from the aspect of application, the flexible-wire traction-type capsule endoscope has a small structure volume, is easy to swallow, and causes small negative reactions to patients.

摘要翻译： 本发明公开了一种柔性牵引型胶囊型内窥镜及其制造方法，其主要包括：容纳在一个体积小的胶囊型内窥镜，并引出用于牵引的柔性线。 柔性牵引式胶囊型内窥镜的制造方法包括模具一体化，薄膜涂布，粘接，成型，组装，密封，线固定等步骤。 根据本发明，通过将传统的胶囊型内窥镜与经处理的袋装组装在一起，最后进行密封固定，制成柔性线牵引型胶囊型内窥镜的成品。 该产品的制造工艺简单易行，原材料天然无污染，价格便宜，加工工艺容易自动化，生产率易于提高; 从应用方面来说，柔性牵引式胶囊型内窥镜的结构体积小，容易吞咽，对患者产生小的负面反应。

公开(公告)号：US09201448B2

公开(公告)日：2015-12-01

申请号：US13536148

申请日：2012-06-28

申请人： Sankaran M. Menon ,  Binta M. Patel ,  Bo Jiang ,  Nancy G. Woodbridge

发明人： Sankaran M. Menon ,  Binta M. Patel ,  Bo Jiang ,  Nancy G. Woodbridge

IPC分类号： G06F1/12 ,  G06F13/42

CPC分类号： G06F1/12

摘要： Observability of internal system-on-chip signals is a difficult problem and it is particularly difficult to observe and debug transactions with different clock domains. However, one embodiment provides observability of internal signals from multiple internal blocks having varying clock domains such as synchronous (common clock) and asynchronous (non common clock) domains. An embodiment provides simultaneous observability of debug data from both synchronous and asynchronous clock domains. An embodiment may also allow sending debug data from both synchronous and asynchronous domains from the SoC. One embodiment outputs internal signals on output pins of the SoC, thereby allowing transactions from one clock domain to be tracked to another clock domain and allowing for the determination of the relationship between the data of differing clock domains. Other embodiments are described herein.

摘要翻译： 内部片上系统信号的可观察性是一个困难的问题，特别难以观察和调试与不同时钟域的交易。 然而，一个实施例提供了具有变化的时钟域（例如同步（公共时钟））和异步（非公共时钟）域的多个内部块的内部信号的可观察性。 一个实施例提供来自同步和异步时钟域的调试数据的同时可观察性。 一个实施例还可以允许从SoC发送来自同步和异步域的调试数据。 一个实施例在SoC的输出引脚上输出内部信号，从而允许来自一个时钟域的事务被跟踪到另一个时钟域，并允许确定不同时钟域的数据之间的关系。 本文描述了其它实施例。

公开(公告)号：US09197731B2

公开(公告)日：2015-11-24

申请号：US14235456

申请日：2012-04-20

申请人： Bo Jiang

发明人： Bo Jiang

IPC分类号： H04M1/725 ,  G10L21/00

CPC分类号： H04M1/72519 ,  G10L21/00 ,  H04M1/72544 ,  H04M2250/74

摘要： This disclosure relates to methods and devices for changing dynamic display effect of mobile phone application by way of voice control. The method includes a recording step, recording an audio file of a voice external to a mobile phone; a judgment step, calculating a voice energy value linearly dependent upon sound volume in the audio file, comparing the voice energy value to a pre-set noise threshold value and performing a rate calculation step when it is greater than the pre-set noise threshold value; a rate calculation step, calculating a corresponding changing rate according to the voice energy value; and an application display step, setting the changing rate of the current application as a calculated changing rate and displaying same for the current application. This disclosure increases the approaches whereby a user controls the dynamic application changing effect and it can be applied to a mobile phone without a touch screen.

摘要翻译： 本公开涉及通过语音控制来改变移动电话应用的动态显示效果的方法和装置。 该方法包括：记录步骤，将移动电话外部的语音的音频文件记录; 判断步骤，计算与所述音频文件中的音量线性相关的语音能量值，将所述语音能量值与预设噪声阈值进行比较，并且当其大于所述预设噪声阈值时执行速率计算步骤 ; 速率计算步骤，根据语音能量值计算相应的变化率; 以及应用显示步骤，将当前应用的变化率设置为计算的变化率，并对当前应用进行显示。 本公开增加了用户控制动态应用改变效果的方法，并且可以将其应用于没有触摸屏的移动电话。

公开(公告)号：US20150299690A1

公开(公告)日：2015-10-22

申请号：US14439746

申请日：2013-12-05

申请人： Bo JIANG ,  Jun ZHUANG ,  MERCK SHARP & DOHME CORP.

发明人： Bo Jiang ,  Jun Zhuang

IPC分类号： C12N9/00 ,  C12P21/00

CPC分类号： C12N9/93 ,  C07K14/39 ,  C12P21/00 ,  C12P21/005 ,  C12Y603/02019

摘要： The present invention relates to novel engineered lower eukaryotic host cells for expressing heterologous proteins and to methods of generating such strains. Lower eukaryotic host cells can be engineered to produce heterologous proteins. Further, lower eukaryotic host cells can be glyco-engineered to produce glycoproteins where the N- or O-linked glycosylation are modified from their native forms.

摘要翻译： 本发明涉及用于表达异源蛋白质的新型工程化低级真核宿主细胞和产生这种菌株的方法。 较低的真核宿主细胞可以被工程化以产生异源蛋白质。 此外，低级真核宿主细胞可以糖加工以产生糖蛋白，其中N-或O-连接的糖基化从其天然形式修饰。