Abstract:
Compounds which inhibit the activity of anti-apoptotic Mcl-1 protein, compositions containing the compounds and methods of treating diseases during which are expressed the Mcl-1 protein are disclosed.
Abstract:
The present invention provides for a sealer/primer that is generally cured at low bake temperatures. The composition utilizes a resin system to provide both conductivity and adhesion of the coating onto plastic substrates. The present invention uses a polyester, such as one that includes unsaturated polyester, in combination with other resins, including an acrylic, crosslinking agent and conductive pigment to create a conductive primer that can be cured at low temperatures. The composition can be applied through traditional application equipment, seals the surface of the substrate to which it is applied, and cures to an acceptable surface for further processing, such as painting.
Abstract:
Disclosed are compounds which inhibit the activity of anti-apoptotic protein family members, compositions containing the compounds and uses of the compounds for preparing medicaments for treating diseases during which occurs expression one or more than one of an anti-apoptotic protein family member.
Abstract:
Compounds which inhibit the activity of anti-apoptotic family protein members, compositions containing the compounds and methods of treating diseases during which occur expression one or more than one of an anti-apoptotic family protein member are disclosed.
Abstract:
Compounds which inhibit the activity of anti-apoptotic family protein members, compositions containing the compounds and methods of treating diseases during which occur expression one or more than one of an anti-apoptotic family protein member are disclosed.
Abstract:
Disclosed are compounds which inhibit the activity of anti-apoptotic protein family members, compositions containing the compounds and uses of the compounds for preparing medicaments for treating diseases during which occurs expression one or more than one of an anti-apoptotic protein family member.
Abstract:
The invention relates to a communication method between a fixed telephone and a PHS mobile phone by means of a two-way conversation function, which comprises the steps of registering a PHS mobile phone and a fixed telephone having a PHS mobile two-way communication module installed therein in the same subsystem group to get connected, such that the PHS mobile phone and the fixed telephone can communicate with each other via a wireless channel interface; using the PHS mobile phone to send a voice to the fixed telephone; using the fixed telephone to send the voice to a communication terminal of the opposite party and then to the user's PHS mobile phone via the conversation mode; and enabling the PHS mobile phone to receive the incoming call of the fixed telephone or dial a telephone call via the fixed telephone.
Abstract:
Methods for treating metal substrates are disclosed. These methods, which comprise contacting the surface to be treated with a composition comprising a Mannich-derivatized polyether, improve the corrosion resistance and/or adhesion properties of the treated surface. Similar methods for treating polymeric substrates are disclosed.
Abstract:
Disclosed are compounds which inhibit the activity of anti-apoptotic protein family members, compositions containing the compounds and uses of the compounds for preparing medicaments for treating diseases during which occurs expression one or more than one of an anti-apoptotic protein family member.
Abstract:
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.