公开(公告)号：US3047992A

公开(公告)日：1962-08-07

申请号：US75568658

申请日：1958-08-18

Applicant: EXXON RESEARCH ENGINEERING CO

Inventor： JONES JR WILLIAM C

IPC: B01D53/04 ,  B01J20/281 ,  G01N30/56

CPC classification number: G01N30/56 ,  B01J20/281 ,  B01J2220/54 ,  G01N30/48

公开(公告)号：US11692979B2

公开(公告)日：2023-07-04

申请号：US16990414

申请日：2020-08-11

Applicant: Saudi Arabian Oil Company

Inventor： Joseph Joseph Puthuvelil

IPC: G01N33/18 ,  B01J20/281 ,  G01N30/16 ,  G01N30/02 ,  B01J20/292

CPC classification number: G01N30/48 ,  G01N30/16 ,  G01N33/18 ,  B01J20/292 ,  G01N2030/027

Abstract: The measurement of glutaraldehyde-based biocides in seawater without the use of a derivatization agent. The measurement of glutaraldehyde-based biocides in seawater may be performed without additional components to reduce background interferences. The concentration of a glutaraldehyde-based biocides in a seawater sample is determined using reversed phase liquid chromatography and a gradient mobile phase of acetonitrile and deionized water. Systems for determining the concentration of glutaraldehyde-based biocide in a seawater injection system are also provided.

公开(公告)号：US20190195840A1

公开(公告)日：2019-06-27

申请号：US15952367

申请日：2018-04-13

Applicant: TAIHO PHARMACEUTICAL CO., LTD.

Inventor： Yoshinori TOKIMITSU

IPC: B01J20/281 ,  C07H19/06 ,  G01N30/89

CPC classification number: G01N30/48 ,  C07H19/06 ,  G01N30/89 ,  G01N2030/027 ,  G01N2030/486

Abstract: This invention provides a method that is capable of detecting a trifluridine-related substance and a tipiracil-related substance contained in a sample containing trifluridine or a salt thereof and tipiracil or a salt thereof using the same procedure. The method is for detecting a trifluridine-related substance or a tipiracil-related substance or both, the method comprising the step of subjecting a sample containing trifluridine or a salt thereof and tipiracil or a salt thereof to high-performance liquid chromatography using a mobile phase composed of an organic phase and an aqueous phase.

公开(公告)号：US20180345174A1

公开(公告)日：2018-12-06

申请号：US16100816

申请日：2018-08-10

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Larry CUMMINGS

IPC: B01D15/20 ,  G01N30/50 ,  B01J20/281 ,  G01N30/26 ,  C01B25/455 ,  C01B25/32 ,  B01D15/36 ,  B01D15/38 ,  B01J20/04 ,  B01J20/30 ,  B01J20/34

CPC classification number: B01D15/203 ,  B01D15/361 ,  B01D15/3847 ,  B01J20/048 ,  B01J20/282 ,  B01J20/3085 ,  B01J20/34 ,  B01J20/3433 ,  B01J20/3475 ,  C01B25/32 ,  C01B25/327 ,  C01B25/455 ,  G01N30/26 ,  G01N30/48 ,  G01N30/50

Abstract: The present invention discloses methods of regenerating apatite surfaces, for example after purification of a target analyte.

公开(公告)号：US20170007981A1

公开(公告)日：2017-01-12

申请号：US15121806

申请日：2015-02-23

Applicant: SHOWA DENKO K.K.

Inventor： Naoya NAKAJIMA ,  Yoshiji OKADA ,  Hideyuki KONDO

IPC: B01J20/24 ,  B01J20/281 ,  G01N30/60 ,  B01D15/30 ,  B01J20/291

CPC classification number: B01J20/24 ,  B01D15/305 ,  B01J20/265 ,  B01J20/286 ,  B01J20/289 ,  B01J20/291 ,  B01J20/321 ,  B01J20/3219 ,  B01J20/3248 ,  B01J20/3251 ,  B01J20/34 ,  G01N30/48 ,  G01N30/482 ,  G01N30/60 ,  G01N30/88 ,  G01N33/02 ,  G01N2030/027

Abstract: A packing material for liquid chromatography, which is excellent in durability, and a column for liquid chromatography, which is filled with the packing material, are provided. The packing material for liquid chromatography is characterized by comprising a hydrophilic resin containing a polyvinyl alcohol resin, to said hydrophilic resin an amino group represented by the formula (1) having been bonded through a spacer. In the formula (1), R1 represents a hydrogen atom or an alkyl group having 1 to 4 carbon atoms, R2 represents an alkyl group having 1 to 6 carbon atoms and having one or more hydroxyl groups, and  represents a bonding position to the spacer.

Abstract translation: 提供一种填充有填充材料的用于液相色谱的耐久性优异的液相色谱柱和液相色谱柱。 用于液相色谱的包装材料的特征在于包含含有聚乙烯醇树脂的亲水性树脂，所述亲水性树脂由通过间隔物结合的式（1）表示的氨基。 式（1）中，R 1表示氢原子或碳原子数1〜4的烷基，R 2表示碳原子数1〜6的烷基，具有一个以上羟基，并且表示与 间隔

公开(公告)号：US20160266074A1

公开(公告)日：2016-09-15

申请号：US15032394

申请日：2014-10-27

Applicant: SHIMADZU CORPORATION ,  AICHI PREFECTURAL GOVERNMENT

Inventor： Eiji UENO ,  Riki KITANO ,  Haruhiko MIYAGAWA

IPC: G01N30/06 ,  B01J20/281

CPC classification number: G01N30/06 ,  B01J20/283 ,  B01J2220/54 ,  G01N30/48 ,  G01N30/7206 ,  G01N30/8665 ,  G01N30/88 ,  G01N2030/486

Abstract: A number of analytes are divided into groups based on at least either the elution position determined by silica gel column chromatography under the same condition or the partition ratio in a hexane-acetonitrile partition method. To each group, a compound obtained by labeling one of the compounds in the group by deuterium and/or carbon is assigned as the surrogate. After those surrogates are added as internal standard substances to a standard sample for the creation of calibration curves, a GC/MS analysis for the sample is performed and a calibration curve is created for each analyte. In the measurement of an unknown sample, the same set of surrogates are added to the sample and the GC/MS analysis is performed. A quantitative determination processor determines the quantity of each analyte by comparing a peak area ratio calculated from the analysis result with a calibration curve read from the database.

Abstract translation: 至少基于相同条件下的硅胶柱色谱法测定的洗脱位置或在己烷 - 乙腈分配方法中的分配比例将多种分析物分成几组。 对于各组，将通过氘和/或碳标记该组中的化合物之一而获得的化合物被指定为替代物。 将这些替代物作为内标物质添加到标准样品中以创建校准曲线后，对样品进行GC / MS分析，并为每个分析物创建校准曲线。 在未知样品的测量中，将相同的替代品组添加到样品中，并进行GC / MS分析。 定量确定处理器通过将从分析结果计算的峰面积比与从数据库读取的校准曲线进行比较来确定每个分析物的量。

公开(公告)号：US20150367252A1

公开(公告)日：2015-12-24

申请号：US14747221

申请日：2015-06-23

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Mark A. Snyder ,  Kimberly C. Brisack

IPC: B01D15/20 ,  B01D15/36

CPC classification number: B01D15/203 ,  B01D15/361 ,  B01D15/3847 ,  B01J20/048 ,  B01J20/282 ,  B01J20/3085 ,  B01J20/34 ,  B01J20/3433 ,  B01J20/3475 ,  C01B25/32 ,  C01B25/327 ,  C01B25/455 ,  G01N30/26 ,  G01N30/48 ,  G01N30/50

Abstract: Disclosed herein are methods of regenerating apatite surfaces, for example after purification of a target analyte.

Abstract translation: 本文公开的是再生磷灰石表面的方法，例如在纯化目标分析物之后。

公开(公告)号：US20150300998A1

公开(公告)日：2015-10-22

申请号：US14477060

申请日：2014-09-04

Applicant: The Board of Trustees of the University of Illinois

Inventor： Kenneth S. Suslick ,  Jacqueline M. Rankin

IPC: B01J20/281 ,  C08L63/00 ,  C08L83/04 ,  G01N30/60

CPC classification number: G01N30/48 ,  B01J20/28097 ,  B01J20/285 ,  B01J2220/86 ,  C08L63/00 ,  C08L83/04 ,  G01N30/6095 ,  G01N2030/486

Abstract: A microcolumn for use in gas chromatography comprises a self-supporting polymer body that functions as a stationary phase and a structural support. The polymer body comprises an enclosed channel having a length L, height h and width w extending therethrough and one or more channel walls surrounding the enclosed channel. The one or more channel walls are integrally formed with the polymer body. The polymer body and the one or more channel walls may comprise a phase-separated polymer composition.

Abstract translation: 用于气相色谱的微柱包括用作固定相和结构载体的自支撑聚合物体。 聚合物主体包括封闭的通道，其具有延伸穿过其中的长度L，高度h和宽度w以及围绕封闭通道的一个或多个通道壁。 一个或多个通道壁与聚合物主体一体地形成。 聚合物体和一个或多个通道壁可以包含相分离的聚合物组合物。

公开(公告)号：US20140260535A1

公开(公告)日：2014-09-18

申请号：US14208088

申请日：2014-03-13

Applicant: R. Andrew McGill ,  Robert Furstenberg ,  Viet K. Nguyen ,  Chris Kendziora ,  Michael Papantonakis ,  Todd H. Stievater

Inventor： R. Andrew McGill ,  Robert Furstenberg ,  Viet K. Nguyen ,  Chris Kendziora ,  Michael Papantonakis ,  Todd H. Stievater

IPC: G01N30/72

CPC classification number: G01N30/02 ,  G01N21/0332 ,  G01N21/3504 ,  G01N21/39 ,  G01N21/552 ,  G01N21/658 ,  G01N21/7746 ,  G01N30/48 ,  G01N30/6034 ,  G01N30/6082 ,  G01N30/74 ,  G01N2021/4761 ,  G01N2030/025

Abstract: A chemical detector for rapid, simultaneous detection of multiple chemicals including chemical warfare agents, toxic industrial chemicals, and explosives having one or more gas chromatography columns each with a chemosorbent or a chemo-reactive stationary phase and an infrared-transparent base, a bright infrared light source, a mechanism to direct the light source to any point along any of the columns, and an infrared sensor. Another disclosed detector has one or more gas chromatography columns each on the surface of a substrate having at least one infrared-transparent waveguide pattern, a bright infrared light source, and at least one ring resonator for each column, where each ring resonator is coated with a chemosorbent or a chemo-reactive stationary phase, and where each ring resonator spectroscopically probes the stationary phase. Also disclosed are the related methods for chemical detection.

Abstract translation: 一种用于快速，同时检测多种化学品的化学检测器，包括化学战剂，有毒工业化学品和具有一个或多个气相色谱柱的爆炸物，每个气相色谱柱均具有化学吸附剂或化学反应性固定相和红外线透明底物， 光源，将光源引导到沿着任何列的任何点的机构以及红外传感器。 另一种公开的检测器具有一个或多个气相色谱柱，每个气相色谱柱各自在基板的表面上，其具有至少一个红外线透明波导图案，亮红外光源和每列的至少一个环形谐振器，其中每个环形谐振器涂覆有 化学吸附剂或化学反应性固定相，并且其中每个环状共振器光谱地探测固定相。 还公开了用于化学检测的相关方法。

公开(公告)号：US20130153479A1

公开(公告)日：2013-06-20

申请号：US13764394

申请日：2013-02-11

Applicant: INTRINSIC BIOPROBES, INC.

Inventor： Kemmons Tubbs ,  Karl F. Gruber ,  Randall W. Nelson

IPC: G01N33/68

CPC classification number: G01N33/6845 ,  B01J20/28097 ,  B01J20/281 ,  B01J20/286 ,  B01J20/32 ,  B01J20/3204 ,  B01J20/3208 ,  B01J20/3242 ,  B01J20/3259 ,  B01J20/3265 ,  B01J20/3272 ,  B01J20/3274 ,  B01J20/3282 ,  B01J2220/54 ,  B01J2220/64 ,  B82Y30/00 ,  G01N30/02 ,  G01N30/48 ,  G01N30/6095 ,  G01N33/54366 ,  G01N33/545 ,  G01N33/6803 ,  G01N2570/00 ,  H01J49/164 ,  H01J49/40 ,  Y10T436/255 ,  B01D15/3804

Abstract: Described is an affinity microcolumn comprising a high surface area material, which has high flow properties and a low dead volume, contained within a housing and having affinity reagents bound to the surface of the high surface area material that are either activated or activatable. The affinity reagents bound to the surface of the affinity microcolumn further comprise affinity receptors for the integration into high throughput analysis of biomolecules.

Abstract translation: 描述了一种亲和力微柱，其包含高表面积材料，其具有包含在壳体内的高流动性和低死体积，并且具有结合到高表面积材料的表面的亲和试剂，其被激活或可激活。 结合亲和微柱表面的亲和试剂还包含用于整合生物分子的高通量分析的亲和受体。